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The cover features Figure 3 "COVID-19 vulnerability as an age-related disease“ from Blagosklonny

Volume 12, Issue 11

15 June, 2020
pp 10001—11160

About the Cover

The cover features Figure 3 "COVID-19 vulnerability as an age-related disease“ from Blagosklonny


Explore This Issue

Editorial

In silico phenotype projection of endothelial ERK1/2 signaling

Michael Simons, Jeffrey R. Gulcher, Thomas W. Chittenden,
https://doi.org/10.18632/aging.103529 pp 10001—10003
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Reviews

COVID-19
From causes of aging to death from COVID-19

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.103493 pp 10004—10021
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COVID-19
Potential mechanisms of hemorrhagic stroke in elderly COVID-19 patients

Haili Wang, Xiaojia Tang, Hongyang Fan, Yuhan Luo, Yuxia Song, Yao Xu, Yingzhu Chen,
https://doi.org/10.18632/aging.103335 pp 10022—10034
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Research Perspective

COVID-19
Microdose lithium reduces cellular senescence in human astrocytes - a potential pharmacotherapy for COVID-19?

Tania Viel, Shankar Chinta, Anand Rane, Manish Chamoli, Hudson Buck, Julie Andersen,
https://doi.org/10.18632/aging.103449 pp 10035—10040
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Priority Research Paper

Lactate dehydrogenase expression modulates longevity and neurodegeneration in Drosophila melanogaster

Dani M. Long, Ariel K. Frame, Patrick N. Reardon, Robert C. Cumming, David A. Hendrix, Doris Kretzschmar, Jadwiga M. Giebultowicz,
https://doi.org/10.18632/aging.103373 pp 10041—10058
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Research Papers

COVID-19
Infection with SARS-CoV-2 causes abnormal laboratory results of multiple organs in patients

Ai-Ping Yang, Hui-Ming Li, Wen-Qiang Tao, Xue-Jing Yang, Min Wang, Wen-Juan Yang, Jian-Ping Liu,
https://doi.org/10.18632/aging.103255 pp 10059—10069
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COVID-19
Comparison of clinical characteristics and outcomes of patients with coronavirus disease 2019 at different ages

Mengmeng Zhao, Menglong Wang, Jishou Zhang, Jian Gu, Pingan Zhang, Yao Xu, Jing Ye, Zhen Wang, Di Ye, Wei Pan, Bo Shen, Hua He, Mingxiao Liu, Menglin Liu, Zhen Luo, Dan Li, Jianfang Liu, Jun Wan,
https://doi.org/10.18632/aging.103298 pp 10070—10086
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COVID-19
ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy

Rosanna Asselta, Elvezia Maria Paraboschi, Alberto Mantovani, Stefano Duga,
https://doi.org/10.18632/aging.103415 pp 10087—10098
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Age-related cognitive decline in baboons: modeling the prodromal phase of Alzheimer's disease and related dementias

Stephanny Lizarraga, Etienne W. Daadi, Gourav Roy-Choudhury, Marcel M. Daadi,
https://doi.org/10.18632/aging.103272 pp 10099—10116
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Salvianolic Acid B improves cognitive impairment by inhibiting neuroinflammation and decreasing Aβ level in Porphyromonas gingivalis-infected mice

Jianwei Liu, Yiling Wang, Jing Guo, Jinyan Sun, Qinfeng Sun,
https://doi.org/10.18632/aging.103306 pp 10117—10128
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Clusterin exerts a cytoprotective and antioxidant effect in human osteoarthritic cartilage

Chiara Tarquini, Sabina Pucci, Maria Giovanna Scioli, Elena Doldo, Sara Agostinelli, Federico D’Amico, Alessandra Bielli, Amedeo Ferlosio, Emanuele Caredda, Umberto Tarantino, Augusto Orlandi,
https://doi.org/10.18632/aging.103310 pp 10129—10146
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Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice

Francesca Eroli, Kristina Johnell, María Latorre Leal, Chiara Adamo, Sarah Hilmer, Jonas W. Wastesson, Angel Cedazo-Minguez, Silvia Maioli,
https://doi.org/10.18632/aging.103315 pp 10147—10161
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First-in-class candidate therapeutics that target mitochondria and effectively prevent cancer cell metastasis: mitoriboscins and TPP compounds

Béla Ózsvári, Federica Sotgia, Michael P. Lisanti,
https://doi.org/10.18632/aging.103336 pp 10162—10179
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Reduced expression of microRNA-130a promotes endothelial cell senescence and age-dependent impairment of neovascularization

Wahiba Dhahri, Sylvie Dussault, Éliane Légaré, François Rivard, Michel Desjarlais, Raphael Mathieu, Alain Rivard,
https://doi.org/10.18632/aging.103340 pp 10180—10193
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Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines

William H. Chappell, Saverio Candido, Stephen L. Abrams, Shaw M. Akula, Linda S. Steelman, Alberto M. Martelli, Stefano Ratti, Lucio Cocco, Melchiorre Cervello, Giuseppe Montalto, Ferdinando Nicoletti, Massimo Libra, James A. McCubrey,
https://doi.org/10.18632/aging.103377 pp 10194—10210
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Effects of intraovarian injection of autologous platelet rich plasma on ovarian reserve and IVF outcome parameters in women with primary ovarian insufficiency

Yigit Cakiroglu, Ayse Saltik, Aysen Yuceturk, Ozge Karaosmanoglu, Sule Yildirim Kopuk, Richard T. Scott Jr., Bulent Tiras, Emre Seli,
https://doi.org/10.18632/aging.103403 pp 10211—10222
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Long non-coding RNA SNHG1 activates HOXA1 expression via sponging miR-193a-5p in breast cancer progression

Jun Li, Tianyu Zeng, Wei Li, Hao Wu, Chunxiao Sun, Fan Yang, Mengzhu Yang, Ziyi Fu, Yongmei Yin,
https://doi.org/10.18632/aging.103123 pp 10223—10234
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miR-195-5p alleviates acute kidney injury through repression of inflammation and oxidative stress by targeting vascular endothelial growth factor A

Yong Xu, Wei Jiang, Lili Zhong, Hailun Li, Lin Bai, Xiaoling Chen, Yongtao Lin, Donghui Zheng,
https://doi.org/10.18632/aging.103160 pp 10235—10245
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miR-623 suppresses cell proliferation, migration and invasion through direct inhibition of XRCC5 in breast cancer

Qing Li, Jiangtao Liu, Yanli Jia, Tingting Li, Mei Zhang,
https://doi.org/10.18632/aging.103182 pp 10246—10258
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Structural plasticity of the bilateral hippocampus in glioma patients

Taoyang Yuan, Jianyou Ying, Zhentao Zuo, Songbai Gui, Zhixian Gao, Guilin Li, Yazhuo Zhang, Chuzhong Li,
https://doi.org/10.18632/aging.103212 pp 10259—10274
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UBE2T promotes glioblastoma invasion and migration via stabilizing GRP78 and regulating EMT

Peng Huang, Yuduo Guo, Zitong Zhao, Weihai Ning, Haoran Wang, Chunyu Gu, Mingshan Zhang, Yanming Qu, Hongwei Zhang, Yongmei Song,
https://doi.org/10.18632/aging.103239 pp 10275—10289
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Interactive effect of MTHFR C677T polymorphism and sex on symptoms and cognitive functions in Chinese patients with chronic schizophrenia

Jie Gao, Mei Hong Xiu, Dian Ying Liu, Chang Wei Wei, Xiangyang Zhang,
https://doi.org/10.18632/aging.103248 pp 10290—10299
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Alterations in glycolytic/cholesterogenic gene expression in hepatocellular carcinoma

Jianwen Jiang, Qiuxian Zheng, Weiwei Zhu, Xinhua Chen, Haifeng Lu, Deying Chen, Hua Zhang, Min Shao, Lin Zhou, Shusen Zheng,
https://doi.org/10.18632/aging.103254 pp 10300—10316
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Nomogram for the prediction of diabetic nephropathy risk among patients with type 2 diabetes mellitus based on a questionnaire and biochemical indicators: a retrospective study

Yuhong Hu, Rong Shi, Ruohui Mo, Fan Hu,
https://doi.org/10.18632/aging.103259 pp 10317—10336
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Altered expression of fibroblast activation protein-α (FAP) in colorectal adenoma-carcinoma sequence and in lymph node and liver metastases

Jon Danel Solano-Iturri, Maider Beitia, Peio Errarte, Julio Calvete-Candenas, María C. Etxezarraga, Alberto Loizate, Enrique Echevarria, Iker Badiola, Gorka Larrinaga,
https://doi.org/10.18632/aging.103261 pp 10337—10358
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Resveratrol promotes osteogenesis and alleviates osteoporosis by inhibiting p53

Tao Yu, Zaiyan Wang, Xiaomeng You, Haichao Zhou, Wenbao He, Bing Li, Jiang Xia, Hui Zhu, Youguang Zhao, Guangrong Yu, Yuan Xiong, Yunfeng Yang,
https://doi.org/10.18632/aging.103262 pp 10359—10369
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Keap1-Nrf2 signaling activation by Bardoxolone-methyl ameliorates high glucose-induced oxidative injury in human umbilical vein endothelial cells

Jing-Lei Yang, Meng-Yue Sun, Qi Yuan, Shan Tang, Mei-Juan Dong, Ri-Dong Zhang, Yuan-Yuan Liu, Li Mao,
https://doi.org/10.18632/aging.103263 pp 10370—10380
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High circ-SEC31A expression predicts unfavorable prognoses in non-small cell lung cancer by regulating the miR-520a-5p/GOT-2 axis

Mingming Jin, Chunzi Shi, Qian Hua, Tian Li, Chen Yang, Yue Wu, Licong Zhao, Hao Yang, Jiaqi Zhang, Cheng Hu, Gang Huang,
https://doi.org/10.18632/aging.103264 pp 10381—10397
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Testosterone enhances mitochondrial complex V function in the substantia nigra of aged male rats

Tianyun Zhang, Yu Wang, Yunxiao Kang, Li Wang, Hui Zhao, Xiaoming Ji, Yuanxiang Huang, Wensheng Yan, Rui Cui, Guoliang Zhang, Geming Shi,
https://doi.org/10.18632/aging.103265 pp 10398—10414
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CHK2 is essential for spindle assembly and DNA repair during the first cleavage of mouse embryos

Xiao-Han Li, Wen-Jing Li, Jia-Qian Ju, Meng-Hao Pan, Yao Xu, Ming-Hong Sun, Mo Li, Shao-Chen Sun,
https://doi.org/10.18632/aging.103267 pp 10415—10426
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LncRNA PVT1 promotes exosome secretion through YKT6, RAB7, and VAMP3 in pancreatic cancer

Chengming Sun, Peng Wang, Wei Dong, Haishi Liu, Jianmin Sun, Liang Zhao,
https://doi.org/10.18632/aging.103268 pp 10427—10440
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LncRNA SNHG7 promotes cardiac remodeling by upregulating ROCK1 via sponging miR-34-5p

Jie Wang, Shouwen Zhang, Xinhua Li, Maolei Gong,
https://doi.org/10.18632/aging.103269 pp 10441—10456
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Ellagic acid protects mice against sleep deprivation-induced memory impairment and anxiety by inhibiting TLR4 and activating Nrf2

Wenjun Wang, Liudi Yang, Tianlong Liu, Jingwen Wang, Aidong Wen, Yi Ding,
https://doi.org/10.18632/aging.103270 pp 10457—10472
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p53 plays a central role in the development of osteoporosis

Tao Yu, Xiaomeng You, Haichao Zhou, Alex Kang, Wenbao He, Zihua Li, Bing Li, Jiang Xia, Hui Zhu, Youguang Zhao, Guangrong Yu, Yuan Xiong, Yunfeng Yang,
https://doi.org/10.18632/aging.103271 pp 10473—10487
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Overexpression of hsa_circ_0136666 predicts poor prognosis and initiates osteosarcoma tumorigenesis through miR-593-3p/ZEB2 pathway

Chao Zhang, Haibo Zhou, Kaizhen Yuan, Raoying Xie, Chun Chen,
https://doi.org/10.18632/aging.103273 pp 10488—10496
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Both objective and paradoxical insomnia elicit a stress response involving mitokine production

Morena Martucci, Maria Conte, Rita Ostan, Antonio Chiariello, Filomena Miele, Claudio Franceschi, Stefano Salvioli, Aurelia Santoro, Federica Provini,
https://doi.org/10.18632/aging.103274 pp 10497—10505
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Modification of graphene oxide by angiopep-2 enhances anti-glioma efficiency of the nanoscaled delivery system for doxorubicin

Yue Zhao, Hang Yin, Xiaoyu Zhang,
https://doi.org/10.18632/aging.103275 pp 10506—10516
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LncRNA SOCS2-AS1 inhibits progression and metastasis of colorectal cancer through stabilizing SOCS2 and sponging miR-1264

Zhihai Zheng, Xiaoxiao Li, Heyi You, Xiaofeng Zheng, Xiaojiao Ruan,
https://doi.org/10.18632/aging.103276 pp 10517—10526
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Human amnion-derived mesenchymal stem cells promote osteogenic differentiation of human bone marrow mesenchymal stem cells via H19/miR-675/APC axis

Xiaojie Ma, Yifeng Bian, Hua Yuan, Ning Chen, Yongchu Pan, Weina Zhou, Shiyu Gao, Xin Du, Shushu Hao, Zixin Yan, Xuan Li, Keyue Liu, Fan Xu, Yuli Wang, Yifei Du,
https://doi.org/10.18632/aging.103277 pp 10527—10543
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Long noncoding RNA LINC00460 conduces to tumor growth and metastasis of hepatocellular carcinoma through miR-342-3p-dependent AGR2 up-regulation

Han Hong, Chengjun Sui, Tao Qian, Xiaoyong Xu, Xiang Zhu, Qiang Fei, Jiamei Yang, Minhui Xu,
https://doi.org/10.18632/aging.103278 pp 10544—10555
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T1-11, an adenosine derivative, ameliorates aging-related behavioral physiology and senescence markers in aging mice

Wei-Hsiang Hsu, Young-Ji Shiao, Yen-Ming Chao, Yi-Jeng Huang, Yun-Lian Lin,
https://doi.org/10.18632/aging.103279 pp 10556—10577
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CARM1 promotes non-small cell lung cancer progression through upregulating CCNE2 expression

Deqin Wu, Jing He, Wei Zhang, Kai Wang, Shidai Jin, Jun Li, Wen Gao,
https://doi.org/10.18632/aging.103280 pp 10578—10593
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Coagulation factor 2 thrombin receptor promotes malignancy in glioma under SOX2 regulation

Guojun Gao, Ming Yang, Fan Wang, Ge Dang, Xiaoling Zhang, Jing Zhao, Xiangyang Wang, Baozhe Jin,
https://doi.org/10.18632/aging.103281 pp 10594—10613
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Ursolic acid reverses liver fibrosis by inhibiting interactive NOX4/ROS and RhoA/ROCK1 signalling pathways

Sizhe Wan, Fangyun Luo, Chenkai Huang, Cong Liu, Qingtian Luo, Xuan Zhu,
https://doi.org/10.18632/aging.103282 pp 10614—10632
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Gut microbiota–dependent Trimethylamine N-Oxide are related with hip fracture in postmenopausal women: a matched case-control study

Yakun Liu, Yan-Long Guo, Shan Meng, Hua Gao, Li-Juan Sui, Shaobin Jin, Yang Li, Shao-Guang Fan,
https://doi.org/10.18632/aging.103283 pp 10633—10641
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Epigenome-wide gene–age interaction analysis reveals reversed effects of PRODH DNA methylation on survival between young and elderly early-stage NSCLC patients

Chao Chen, Yongyue Wei, Liangmin Wei, Jiajin Chen, Xin Chen, Xuesi Dong, Jieyu He, Lijuan Lin, Ying Zhu, Hui Huang, Dongfang You, Linjing Lai, Sipeng Shen, Weiwei Duan, Li Su, Andrea Shafer, Thomas Fleischer, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Rui Wang, Johan Staaf, Åslaug Helland, Manel Esteller, Ruyang Zhang, Feng Chen, David C. Christiani,
https://doi.org/10.18632/aging.103284 pp 10642—10662
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Association between immune-related adverse events and efficacy of PD-1 inhibitors in Chinese patients with advanced melanoma

Jing-Jing Zhao, Xi-Zhi Wen, Ya Ding, Dan-Dan Li, Bao-Yan Zhu, Jing-Jing Li, De-Sheng Weng, Xing Zhang, Xiao-Shi Zhang,
https://doi.org/10.18632/aging.103285 pp 10663—10675
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Modelling biological age based on plasma peptides in Han Chinese adults

Weijie Cao, Deqiang Zheng, Guohua Wang, Jie Zhang, Siqi Ge, Manjot Singh, Hao Wang, Manshu Song, Dong Li, Wei Wang, Xizhu Xu, Youxin Wang,
https://doi.org/10.18632/aging.103286 pp 10676—10686
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Leisure activities and disability in activities of daily living among the oldest-old Chinese population: evidence from the Chinese Longitudinal Healthy Longevity Study

Zhi-Hao Li, Qing Chen, Virginia Byers Kraus, Dong Shen, Xi-Ru Zhang, Pei-Dong Zhang, Wen-Fang Zhong, Yue-Bin Lv, Qing-Mei Huang, Wei-Qi Song, Dong Wang, Xian-Bo Wu, Xiao-Ming Shi, Chen Mao,
https://doi.org/10.18632/aging.103287 pp 10687—10703
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Walking ability and functional status after post-acute care for stroke rehabilitation in different age groups: a prospective study based on propensity score matching

Chung-Yuan Wang, Seido Miyoshi, Chang-Hung Chen, Kai-Chun Lee, Long-Chung Chang, Jo-Hsuan Chung, Hon-Yi Shi,
https://doi.org/10.18632/aging.103288 pp 10704—10714
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Subgroup analysis of proinsulin and insulin levels reveals novel correlations to metabolic indicators of type 2 diabetes

Tangying Li, Huibiao Quan, Huachuan Zhang, Leweihua Lin, Lu Lin, Qianying Ou, Kaining Chen,
https://doi.org/10.18632/aging.103289 pp 10715—10735
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Structural and functional changes of gut microbiota in ovariectomized rats and their correlations with altered bone mass

Sicong Ma, Jinhong Qin, Yongqiang Hao, Ying Shi, Lingjie Fu,
https://doi.org/10.18632/aging.103290 pp 10736—10753
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How non-drug interventions affect the quality of life of patients suffering from progressive cognitive decline and their main caregiver

Benedetta Leidi-Maimone, Marie-Laure Notter-Bielser, Marie-Hélène Laouadi, Sarah Perrin, Hélène Métraux, Daniel Damian, Camille F. Chavan, Mélanie Nsir, Gwendoline Cibelli, Marie-Jo Tâche, Marie-Louise Montandon, Joseph Ghika, Jean-François Démonet, Anne-Véronique Dürst, Andrea Brioschi Guevara,
https://doi.org/10.18632/aging.103291 pp 10754—10771
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Meta-analysis of the association between nut consumption and the risks of cancer incidence and cancer-specific mortality

Dai Zhang, Cong Dai, Linghui Zhou, Yiche Li, Kang Liu, Yu-Jiao Deng, Na Li, Yi Zheng, Qian Hao, Si Yang, Dingli Song, Ying Wu, Zhen Zhai, Shiyi Cao, Zhijun Dai,
https://doi.org/10.18632/aging.103292 pp 10772—10794
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Association of gut microbiota composition and function with an aged rat model of senile osteoporosis using 16S rRNA and metagenomic sequencing analysis

Sicong Ma, Jinhong Qin, Yongqiang Hao, Lingjie Fu,
https://doi.org/10.18632/aging.103293 pp 10795—10808
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LncRNA and mRNA expression profiles reveal the potential roles of lncRNA contributing to regulating dural penetration in clival chordoma

Jiwei Bai, Yixuan Zhai, Shuai Wang, Mingxuan Li, Shuheng Zhang, Chuzhong Li, Songbai Gui, Qi Li, Yazhuo Zhang,
https://doi.org/10.18632/aging.103294 pp 10809—10826
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High mutation load, immune-activated microenvironment, favorable outcome, and better immunotherapeutic efficacy in melanoma patients harboring MUC16/CA125 mutations

Qinghua Wang, Yichen Yang, Meng Yang, Xiangchun Li, Kexin Chen,
https://doi.org/10.18632/aging.103296 pp 10827—10843
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Aberrantly glycosylated integrin α3β1 is a unique urinary biomarker for the diagnosis of bladder cancer

Di Jin, Ruiyun Zhang, Haige Chen, Chong Li,
https://doi.org/10.18632/aging.103297 pp 10844—10862
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Association between renal function impairment and multivessel involvement in patients with acute ST-elevation myocardial infarction

Rei-Yeuh Chang, Han-Lin Tsai, Malcolm Koo, How-Ran Guo,
https://doi.org/10.18632/aging.103299 pp 10863—10872
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miR-137 prevents inflammatory response, oxidative stress, neuronal injury and cognitive impairment via blockade of Src-mediated MAPK signaling pathway in ischemic stroke

Runhui Tian, Bo Wu, Cong Fu, Kaimin Guo,
https://doi.org/10.18632/aging.103301 pp 10873—10895
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SPTBN1 suppresses the progression of epithelial ovarian cancer via SOCS3-mediated blockade of the JAK/STAT3 signaling pathway

Mo Chen, Jia Zeng, Shuyi Chen, Jiajia Li, Huijie Wu, Xuhui Dong, Yuan Lei, Xiuling Zhi, Liangqing Yao,
https://doi.org/10.18632/aging.103303 pp 10896—10911
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Dynamic changes of autophagic flux induced by Abeta in the brain of postmortem Alzheimer’s disease patients, animal models and cell models

Zhimin Long, Jingfei Chen, Yueyang Zhao, Wen Zhou, Qiuhui Yao, Yingxiong Wang, Guiqiong He,
https://doi.org/10.18632/aging.103305 pp 10912—10930
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Hypoxia-preconditioned olfactory mucosa mesenchymal stem cells abolish cerebral ischemia/reperfusion-induced pyroptosis and apoptotic death of microglial cells by activating HIF-1α

Yan Huang, Fengbo Tan, Yi Zhuo, Jianyang Liu, Jialin He, Da Duan, Ming Lu, Zhiping Hu,
https://doi.org/10.18632/aging.103307 pp 10931—10950
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Fibroblast growth factor 2 contributes to the effect of salidroside on dendritic and synaptic plasticity after cerebral ischemia/reperfusion injury

Sisi Li, Yechen Lu, Daofang Ding, Zhenzhen Ma, Xiangxin Xing, Xuyun Hua, Jianguang Xu,
https://doi.org/10.18632/aging.103308 pp 10951—10968
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P22077 inhibits LPS-induced inflammatory response by promoting K48-linked ubiquitination and degradation of TRAF6

Xi-Bao Zhao, Fei-Yang Ji, Hong-Rui Li, Hui-Hui Zhu, Zi-Zhao Zhao, Jing Ling, Qian-Qian Di, Xing-Yu Ma, Wei-Lin Chen,
https://doi.org/10.18632/aging.103309 pp 10969—10982
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The circRNA circIFI30 promotes progression of triple-negative breast cancer and correlates with prognosis

Lei Xing, Rui Yang, Xiaosong Wang, Xiaying Zheng, Xin Yang, Luyu Zhang, Rong Jiang, Guosheng Ren, Junxia Chen,
https://doi.org/10.18632/aging.103311 pp 10983—11003
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Upregulation of Mlxipl induced by cJun in the spinal dorsal horn after peripheral nerve injury counteracts mechanical allodynia by inhibiting neuroinflammation

Hongrui Zhan, Yaping Wang, Shi Yu, Guiyuan Cai, Yanyan Zeng, Junqin Ma, Wei Liu, Wen Wu,
https://doi.org/10.18632/aging.103313 pp 11004—11024
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LncRNA ADAMTS9-AS2 inhibits gastric cancer (GC) development and sensitizes chemoresistant GC cells to cisplatin by regulating miR-223-3p/NLRP3 axis

Niansheng Ren, Tao Jiang, Chengbo Wang, Shilin Xie, Yanwei Xing, Daxun Piao, Tiemin Zhang, Yuekun Zhu,
https://doi.org/10.18632/aging.103314 pp 11025—11041
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Highly expressed STAT1 contributes to the suppression of stemness properties in human paclitaxel-resistant ovarian cancer cells

Fanchen Wang, Lingyun Zhang, Jiao Liu, Jinguo Zhang, Guoxiong Xu,
https://doi.org/10.18632/aging.103317 pp 11042—11060
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T cell stimulation and expansion by SunTag-based clustering of anti-CD3/CD28 scFv

Kunhong Zhong, Zhiyong Liu, Hongjian Li, Shasha Zhao, Yuelong Wang, Wenhao Guo, Xi Zheng, Hui Yang, Gang Guo, Liangxue Zhou, Jianguo Xu, Aiping Tong,
https://doi.org/10.18632/aging.103318 pp 11061—11070
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LINC01419 facilitates hepatocellular carcinoma growth and metastasis through targeting EZH2-regulated RECK

Gong Zhang, Ximin Chen, Lei Ma, Rui Ding, Lihong Zhao, Feng Ma, Xubin Deng,
https://doi.org/10.18632/aging.103321 pp 11071—11084
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The effect of swimming exercise and diet on the hypothalamic inflammation of ApoE-/- mice based on SIRT1-NF-κB-GnRH expression

Xialei Wang, Jingda Yang, Taotao Lu, Zengtu Zhan, Wei Wei, Xinru Lyu, Yijing Jiang, Xiehua Xue,
https://doi.org/10.18632/aging.103323 pp 11085—11099
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ANXA7 promotes the cell cycle, proliferation and cell adhesion-mediated drug resistance of multiple myeloma cells by up-regulating CDC5L

Haiyan Liu, Dan Guo, Yuou Sha, Chenlu Zhang, Yijing Jiang, Lemin Hong, Jie Zhang, Yuwen Jiang, Ling Lu, Hongming Huang,
https://doi.org/10.18632/aging.103326 pp 11100—11115
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Deoxyelephantopin induces apoptosis via oxidative stress and enhances gemcitabine sensitivity in vitro and in vivo through targeting the NF-κB signaling pathway in pancreatic cancer

Daolin Ji, Xiangyu Zhong, Peng Huang, Pengcheng Kang, Kaiming Leng, Wangyang Zheng, Zhidong Wang, Yi Xu, Yunfu Cui,
https://doi.org/10.18632/aging.103327 pp 11116—11138
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Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases

Xixi Zhang, Deming Zhao, Wei Wu, Syed Zahid Ali Shah, Mengyu Lai, Dongming Yang, Jie Li, Zhiling Guan, Wen Li, Hongli Gao, Huafen Zhao, Xiangmei Zhou, Lifeng Yang,
https://doi.org/10.18632/aging.103328 pp 11139—11151
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Theory Article

LSEC model of aging

Laurent Grosse, Dmitry V. Bulavin,
https://doi.org/10.18632/aging.103492 pp 11152—11160
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