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Page: 12 of 2

• Research PaperVolume 17, Issue 9pp 2369-2391

  Runx1 overexpression induces early onset of intervertebral disc degeneration

  Relevance score: 0.00

  Takanori Fukunaga, Martha Elena Diaz-Hernandez, John G. Heller, Changli Zhang, Hicham Drissi

  Keywords: cell senescence, aging, Runx1, nucleus pulposus, intervertebral disc degeneration

  Published in Aging on September 8, 2025

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• Research PaperVolume 16, Issue 12pp 10216-10238

  Oxidative stress-induced EGR1 upregulation promotes NR4A3-mediated nucleus pulposus cells apoptosis in intervertebral disc degeneration

  Relevance score: 0.00

  Si-Kuan Zheng, Xiao-Kun Zhao, Hui Wu, Ding-Wen He, Long Xiong, Xi-Gao Cheng

  Keywords: intervertebral disc degeneration, EGR1, NR4A3, nucleus pulposus, apoptosis

  Published in Aging on June 28, 2024

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• RetractionVolume 16, Issue 10pp 9305-9305

  Retraction for: DNMT3B decreases extracellular matrix degradation and alleviates intervertebral disc degeneration through TRPA1 methylation to inhibit the COX2/YAP axis

  Relevance score: 0.00

  Zhiqiang Luo, Yanchao Ma, Tianning Di, Bing Ma, Hongwei Li, Jiangdong An, Yonggang Wang, Haihong Zhang

  Keywords: intervertebral disc degeneration, nucleus pulposus, extracellular matrix, inflammation, DNA methyltransferase

  Published in Aging on May 31, 2024

• Research PaperVolume 16, Issue 6pp 5050-5064

  Omilancor mitigates the senescence of nucleus pulposus cells induced by DDP through targeting MAP2K6

  Relevance score: 0.00

  Fang Yafeng, Shi Xinpeng, Wei Rong, Cui Guofeng

  Keywords: intervertebral disc degeneration, Omilancor, cellular senescence, MAP2K6

  Published in Aging on March 20, 2024

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• Research PaperVolume 16, Issue 6pp 5370-5386

  Comprehensive analysis of gene expression profiles of annulus fibrosus subtypes and hub genes in intervertebral disc degeneration

  Relevance score: 0.00

  Xiaokun Zhao, Jian Zhang, Jiahao Liu, Jinghong Yuan, Tianlong Wu, Xigao Cheng

  Keywords: intervertebral disc degeneration, annulus fibrosus, molecular subtype, WGCNA, machine learning

  Published in Aging on March 13, 2024

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• Research PaperVolume 15, Issue 24pp 15599-15623

  Unravelling diagnostic clusters and immune landscapes of cuproptosis patterns in intervertebral disc degeneration through dry and wet experiments

  Relevance score: 0.00

  Peng Zhang, Jiahui He, Yanchi Gan, Qi Shang, Honglin Chen, Wenhua Zhao, Jianchao Cui, Gengyang Shen, Yuwei Li, Xiaobing Jiang, Guangye Zhu, Hui Ren

  Keywords: intervertebral disc degeneration, cuproptosis biomarkers, subtype classification, immune microenvironment infiltration, experimental validation

  Published in Aging on December 29, 2023

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• Research PaperVolume 15, Issue 24pp 14764-14790

  Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement

  Relevance score: 0.00

  Yingjing Zhao, Yuxue Mu, Yujia Zou, Zhijian He, Tianxing Lu, Xinhui Wang, Weihang Li, Bo Gao

  Keywords: intervertebral disc degeneration, weighted gene co-expression network analysis, Janus kinase family, high-throughput virtual screening, single-cell transcriptome

  Published in Aging on December 12, 2023

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• Research PaperVolume 15, Issue 23pp 13693-13709

  The antioxidant Glycitin protects against intervertebral disc degeneration through antagonizing inflammation and oxidative stress in nucleus pulposus cells

  Relevance score: 0.00

  Wei Zhao, Yanpei Li, Xiang Cheng, Hui Wei, Peng Li, Lixia Fan, Kaiwen Liu, Shuai Zhang, Hao Wang

  Keywords: intervertebral disc degeneration, Glycitin, inflammation, TNF-α, ROS

  Published in Aging on November 28, 2023

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• Research PaperVolume 15, Issue 10pp 4288-4303

  DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo

  Relevance score: 0.00

  Yang Hou, Jiangang Shi, Yongfei Guo, Guodong Shi

  Keywords: intervertebral disc degeneration, macrophage polarization, DNA methyltransferase 1, sirtuin 6

  Published in Aging on May 17, 2023

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• Research PaperVolume 13, Issue 18pp 22459-22473

  miR-19b-3p relieves intervertebral disc degeneration through modulating PTEN/PI3K/Akt/mTOR signaling pathway

  Relevance score: 0.00

  Yulin Zhao, Aimin Li

  Keywords: intervertebral disc degeneration, miR-19b-3p, PTEN, apoptosis, signaling pathways

  Published in Aging on September 23, 2021

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• Research PaperVolume 13, Issue 16pp 20258-20276

  DNMT3B decreases extracellular matrix degradation and alleviates intervertebral disc degeneration through TRPA1 methylation to inhibit the COX2/YAP axis

  Relevance score: 0.00

  Zhiqiang Luo, Yanchao Ma, Tianning Di, Bing Ma, Hongwei Li, Jiangdong An, Yonggang Wang, Haihong Zhang

  Keywords: intervertebral disc degeneration, nucleus pulposus, extracellular matrix, inflammation, DNA methyltransferase

  Published in Aging on August 24, 2021

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• Research PaperVolume 13, Issue 10pp 14185-14197

  Circular RNA ITCH promotes extracellular matrix degradation via activating Wnt/β-catenin signaling in intervertebral disc degeneration

  Relevance score: 0.00

  Feng Zhang, Feili Lin, Zhiwen Xu, Zheng Huang

  Keywords: intervertebral disc degeneration, extracellular matrix ECM degradation, circITCH, miR-17-5p, SOX4

  Published in Aging on May 18, 2021

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• Research PaperVolume 13, Issue 7pp 10703-10723

  ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration

  Relevance score: 0.00

  Jingyu Ding, Renjie Zhang, Huimin Li, Qiang Ji, Xiaomin Cheng, Rick Francis Thorne, Hubert Hondermarck, Xiaoying Liu, Cailiang Shen

  Keywords: intervertebral disc degeneration (IVDD), nucleus pulposus mesenchymal stem cells (NP-MSCs), acid sensing ion channels (ASICs), cellular senescence

  Published in Aging on April 6, 2021

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• Research PaperVolume 12, Issue 8pp 7534-7548

  Protective effects of autophagy and NFE2L2 on reactive oxygen species-induced pyroptosis of human nucleus pulposus cells

  Relevance score: 0.00

  Zhibiao Bai, Wei Liu, Danshuang He, Yiyang Wang, Weiwei Yi, Changqi Luo, Jieliang Shen, Zhenming Hu

  Keywords: intervertebral disc degeneration, nucleus pulposus cells, pyroptosis, transcription factor, autophagy

  Published in Aging on April 22, 2020

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• Research PaperVolume 11, Issue 23pp 10814-10825

  Long noncoding RNA LINC00958 accelerates the proliferation and matrix degradation of the nucleus pulposus by regulating miR-203/SMAD3

  Relevance score: 0.00

  Kunchi Zhao, Yang Zhang, Hongping Yuan, Mingming Zhao, Dongxu Zhao

  Keywords: intervertebral disc degeneration, LINC00958, miR-203, nucleus pulposus

  Published in Aging on December 5, 2019

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• Research PaperVolume 11, Issue 22pp 10499-10512

  Melatonin modulates IL-1β-induced extracellular matrix remodeling in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration and inflammation

  Relevance score: 0.00

  Yan Zhang, Fan He, Zhi Chen, Qihang Su, Meijun Yan, Qiang Zhang, Jun Tan, Lie Qian, Yingchao Han

  Keywords: intervertebral disc degeneration, nucleus pulposus cells, melatonin, inflammation

  Published in Aging on November 26, 2019

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• Research PaperVolume 11, Issue 22pp 10252-10265

  Metformin decreases LPS-induced inflammatory response in rabbit annulus fibrosus stem/progenitor cells by blocking HMGB1 release

  Relevance score: 0.00

  Yingchao Han, Feng Yuan, Chao Deng, Fan He, Yan Zhang, Hongxing Shen, Zhi Chen, Lie Qian

  Keywords: intervertebral disc degeneration, annulus fibrosis stem cells, cell senescence, HMGB1, metformin

  Published in Aging on November 26, 2019

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• Research PaperVolume 11, Issue 18pp 7961-7977

  Kinsenoside ameliorates intervertebral disc degeneration through the activation of AKT-ERK1/2-Nrf2 signaling pathway

  Relevance score: 0.00

  Yanqiu Wang, Rui Zuo, Ziwen Wang, Liwen Luo, Junlong Wu, Chao Zhang, Minghan Liu, Chunmeng Shi, Yue Zhou

  Keywords: kinsenoside, intervertebral disc degeneration, apoptosis, senescence, Nrf2, oxidative stress

  Published in Aging on September 23, 2019

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• Research PaperVolume 10, Issue 8pp 2001-2015

  MicroRNA-221 silencing attenuates the degenerated phenotype of intervertebral disc cells

  Relevance score: 0.00

  Letizia Penolazzi, Elisabetta Lambertini, Leticia Scussel Bergamin, Tosca Roncada, Pasquale De Bonis, Michele Cavallo, Roberta Piva

  Keywords: intervertebral disc cells, intervertebral disc degeneration, gene silencing, microRNA-221, FOXO3

  Published in Aging on August 20, 2018

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• Research PaperVolume 14, Issue 10pp 4572-4585

  Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis

  Relevance score: 0.00

  Xiao-Bo Zhang, Si-Qi Xu, Yi-Geng Hui, Hai-Yu Zhou, Yi-Cun Hu, Rui-Hao Zhang, Xi-Dan Gao, Chang-Ming Zheng

  Keywords: lactotransferrin, intervertebral disc degeneration, bioinformatics, nucleus pulposus cell, mechanism

  Published in Aging on May 25, 2022

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