Volume 16, Issue 12

June 30, 2024pp 10201—10669

About the Cover

The cover features Figure 1 "Senescent cell-derived vaccines: sources of specific antigens for cancer immunotherapy" from Pessoa et al.

Editorial

Aging retinal pigmented epithelium: omics-based insights into vision decline

Ioan V. Matei, Luminita Paraoan

https://doi.org/10.18632/aging.205914pp 10201—10202

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Research Papers

Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome

Sebastiano Giallongo, Jessica Ferrigno, Rosario Caltabiano, Giuseppe Broggi, Amer M. Alanazi, Alfio Distefano, Emanuela Tropea, Antonella Tramutola, Marzia Perluigi, Giovanni Li Volti, Eugenio Barone, Ignazio Alberto Barbagallo

https://doi.org/10.18632/aging.205970pp 10203—10215

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Oxidative stress-induced EGR1 upregulation promotes NR4A3-mediated nucleus pulposus cells apoptosis in intervertebral disc degeneration

Si-Kuan Zheng, Xiao-Kun Zhao, Hui Wu, Ding-Wen He, Long Xiong, Xi-Gao Cheng

https://doi.org/10.18632/aging.205920pp 10216—10238

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MiR-33a-5p in stored red blood cells regulates genes of innate immune response and promotes inflammation

Jingrui Zhang, Dan Zhang, Jing Zhao, Wei Zheng

https://doi.org/10.18632/aging.205925pp 10239—10251

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Characterization of tumor endothelial cells (TEC) in gastric cancer and development of a TEC-based risk signature using single-cell RNA-seq and bulk RNA-seq data

Meng Fan, Xiaofei Xu, Yu Hu

https://doi.org/10.18632/aging.205928pp 10252—10270

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Reduced expression of E-cadherin correlates with poor prognosis and unfavorable clinicopathological features in gastric carcinoma: a meta-analysis

Genlin Lu, Zhai Cai, Renya Jiang, Fei Tong, Jinming Tu, Yandong Chen, Yinglan Fu, Jingyi Sun, Tao Zhang

https://doi.org/10.18632/aging.205929pp 10271—10298

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Mining key circadian biomarkers for major depressive disorder by integrating bioinformatics and machine learning

Yuhe Shi, Jue Zhu, Chaowen Hou, Xiaoling Li, Qiaozhen Tong

https://doi.org/10.18632/aging.205930pp 10299—10320

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Identification of VEGFs-related gene signature for predicting microangiogenesis and hepatocellular carcinoma prognosis

Shengpan Jiang, Guoting Zhu, Yiqing Tan, Tao Zhou, Shilin Zheng, Fuhua Wang, Wenfeng Lei, Xuan Liu, Jinjun Du, Manman Tian

https://doi.org/10.18632/aging.205931pp 10321—10347

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Identification of JUN gene and cellular microenvironment in response to PD-1 blockade treatment in lung cancer patients via single-cell RNA sequencing

Yuxuan Wang, Tao Ran, Yunke Li, Lei Tian, Lifeng Yang, Zhidong Liu, Biao Yao

https://doi.org/10.18632/aging.205932pp 10348—10365

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Genetically predicted 91 circulating inflammatory proteins in relation to risk of urological malignancies: a Mendelian randomization study

Jianxiong Xu, Ru Chen, Yucheng Yang, Sufang Xu, Lijing Yao

https://doi.org/10.18632/aging.205934pp 10366—10379

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Therapeutic targets of formononetin for treating prostate cancer at the single-cell level

Jiawei Li, Zhaoquan Huang, Ping Wang, Rong Li, Li Gao, Keng Po Lai

https://doi.org/10.18632/aging.205935pp 10380—10401

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Application of angiogenesis-related genes associated with immune infiltration in the molecular typing and diagnosis of acute myocardial infarction

Guoqing Liu, Wang Liao, Xiangwen Lv, Miaomiao Zhu, Xingqing Long, Jian Xie

https://doi.org/10.18632/aging.205936pp 10402—10423

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The beneficial effects of Rosuvastatin in inhibiting inflammation in sepsis

Ziming Tang, Zheng Ning, Zexuan Li

https://doi.org/10.18632/aging.205937pp 10424—10434

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Inhibition of non-small cell lung cancer metastasis by knocking down APE1 through regulating myeloid-derived suppressor cells-induced immune disorders

Zhenlong Zhang, Yuchen Lin, Xiaojie Pan, Shuchen Chen

https://doi.org/10.18632/aging.205938pp 10435—10445

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Notoginsenoside R1 (NGR1) regulates the AGE-RAGE signaling pathway by inhibiting RUNX2 expression to accelerate ferroptosis in breast cancer cells

Wenxin Li, Yan Guo, Zhuangyu Xu, Fubo Li, Yi Dong, Fan Xu

https://doi.org/10.18632/aging.205940pp 10446—10461

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MATN4 as a target gene of HIF-1α promotes the proliferation and metastasis of osteosarcoma

Lu Zhang, Yujie Pan, Feng Pan, Songsong Huang, Fengyan Wang, Zhirui Zeng, Houping Chen, Xiaobin Tian

https://doi.org/10.18632/aging.205941pp 10462—10476

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Causal role of immune cells in prostate cancer: a bidirectional Mendelian-randomization analyses

Mingyan Zhong, Xiangpeng Zhan, Fang-Ping Zhong

https://doi.org/10.18632/aging.205942pp 10477—10488

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Identification of a signature of histone modifiers in kidney renal clear cell carcinoma

Yongming Huang, Zhongsheng Yang, Ying Tang, Hua Chen, Tairong Liu, Guanghua Peng, Xin Huang, Xiaolong He, Ming Mei, Chuance Du

https://doi.org/10.18632/aging.205944pp 10489—10511

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The crosstalk role of CDKN2A between tumor progression and cuproptosis resistance in colorectal cancer

Xifu Cheng, Famin Yang, Yuanheng Li, Yuke Cao, Meng Zhang, Jiameng JI, Yuxiao Bai, Qing Li, Qiongfang Yu, Dian Gao

https://doi.org/10.18632/aging.205945pp 10512—10538

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Diagnostic value of galectin-3, fractalkine, IL-6, miR-21 and cardiac troponin I in human ischemic cardiomyopathy

Le Wang, Min Li, Mingqi Zheng, Yida Tang, Zhiyu Yang, Guoping Ma, Qinghou Zheng, Liu Li, Yu Wang, Fangfang Ma, Gang Liu

https://doi.org/10.18632/aging.205953pp 10539—10545

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NAT1 inhibits liver metastasis of colorectal cancer by regulating EMT and glycolysis

Wang Gu, Chen Li, Tingting Shen, Li Tong, Wenkang Yuan, Xiaofei Zheng, Tianqi Wang, Siyu Wang, Benshuai Zhu, Chong Zhang, Chao Zhang

https://doi.org/10.18632/aging.205957pp 10546—10562

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Prescription glucocorticoid medication and iridocyclitis are associated with an increased risk of senile cataract occurrence: a Mendelian randomization study

Rui Wen, Yu-Jia Xi, Ran Zhang, Si-Jia Hou, Jin-Yu Shi, Jin-Yi Chen, He-Yi Zhang, Jun Qiao, Yi-Qian Feng, Sheng-Xiao Zhang

https://doi.org/10.18632/aging.205963pp 10563—10578

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Multi omics analysis of mitophagy subtypes and integration of machine learning for predicting immunotherapy responses in head and neck squamous cell carcinoma

Junzhi Liu, Huimin Li, Qiuping Dong, Zheng Liang

https://doi.org/10.18632/aging.205964pp 10579—10614

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Identification and validation of key genes in gastric cancer: insights from in silico analysis, clinical samples, and functional assays

Xiaofeng Pei, Yuanling Luo, Huanwen Zeng, Muhammad Jamil, Xiaodong Liu, Bo Jiang

https://doi.org/10.18632/aging.205965pp 10615—10635

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Comprehensive single-cell and bulk RNA-seq analyses reveal a novel CD8⁺ T cell-associated prognostic signature in ovarian cancer

Yi-Ling Han, Zhou Fang, Zhi-Jie Gao, Wen-Ge Li, Jing Yang

https://doi.org/10.18632/aging.205966pp 10636—10656

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Review

Senescent cell-derived vaccines: a new concept towards an immune response against cancer and aging?

João Pessoa, Sandrina Nóbrega-Pereira, Bruno Bernardes de Jesus

https://doi.org/10.18632/aging.205975pp 10657—10665

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Correction

Correction for: TMX family genes and their association with prognosis, immune infiltration, and chemotherapy in human pan-cancer

Na Luo, Zhiqiang Mei, Qiqi Zhang, Hong Tang, Runlan Wan, Anni Deng, Xiaopan Zou, Chaoxiang Lv

https://doi.org/10.18632/aging.205990pp 10666—10667

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Retraction

Retraction of: Silencing of circular RNA_0000326 inhibits cervical cancer cell proliferation, migration and invasion by boosting microRNA-338-3p-dependent down-regulation of CDK4

Zhaoxin Wang, Chenchen Ren, Li Yang, Xiaoan Zhang, Jiaxi Liu, Yuanhang Zhu, Dongyuan Jiang

https://doi.org/10.18632/aging.206014pp 10668—10669

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