Volume 14, Issue 10

31 May, 2022
pp 4189—4617

About the Cover

The cover features Figure 6 "Schematic showing the function(s) of cell adhesion molecules, cytokines, and chemokines" from Nashine et al.

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Editorials

Aging, cardiorespiratory fitness and sympathetic transduction

Myles W. O’Brien, Said Mekary, Derek S. Kimmerly,

https://doi.org/10.18632/aging.204091 pp 4189—4190

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Molecular markers associated with cognitive impairment in centenarians

Tinna Stevnsner, Ines Sanchez-Roman,

https://doi.org/10.18632/aging.204094 pp 4191—4192

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Epigenetics-based treatment strategies for Alzheimer’s disease

Qing Cao, Wei Wang, Zhen Yan,

https://doi.org/10.18632/aging.204096 pp 4193—4194

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Priority Research Paper

Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism

Thorsten R. Doeppner, Cristin Coman, Daiana Burdusel, Diana-Larisa Ancuta, Ulf Brockmeier, Daniel Nicolae Pirici, Kuang Yaoyun, Dirk M. Hermann, Aurel Popa-Wagner,

https://doi.org/10.18632/aging.204069 pp 4195—4210

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Research Papers

COVID-19
The roles of inactivated vaccines in older patients with infection of Delta variant in Nanjing, China

Xiao-Chun Song, Xue-Hui Zhou, Jing-Hui Cheng, Wen-Hao Zhang, Xiao Shen, Huan Xu, Shuai Nie, Ji-Lai Xiao, Fang Sun, Chang Shu, Jiu-Dong Chen, Yan Tang, Xiang Wang, Xin-Pei Sun, Jia-Kui Sun, Ping Feng, Qian-Kun Shi,

https://doi.org/10.18632/aging.204085 pp 4211—4219

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Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence

Ryan Wallis, Deborah Milligan, Bethany Hughes, Hannah Mizen, José Alberto López-Domínguez, Ugochim Eduputa, Eleanor J. Tyler, Manuel Serrano, Cleo L. Bishop,

https://doi.org/10.18632/aging.204072 pp 4220—4246

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Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)

Sonali Nashine, Pinchas Cohen, Junxiang Wan, M. Cristina Kenney,

https://doi.org/10.18632/aging.204074 pp 4247—4269

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Identification of combined biomarkers for predicting the risk of osteoporosis using machine learning

Zhenlong Zheng, Xianglan Zhang, Bong-Kyeong Oh, Ki-Yeol Kim,

https://doi.org/10.18632/aging.204084 pp 4270—4280

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Aryl hydrocarbon receptor blocks aging-induced senescence in the liver and fibroblast cells

Ana Nacarino-Palma, Eva M. Rico-Leo, Judith Campisi, Arvind Ramanathan, Francisco J. González-Rico, Claudia M. Rejano-Gordillo, Ana Ordiales-Talavero, Jaime M. Merino, Pedro M. Fernández-Salguero,

https://doi.org/10.18632/aging.204103 pp 4281—4304

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MRTF-A-mediated protection against amyloid-β-induced neuronal injury correlates with restoring autophagy via miR-1273g-3p/mTOR axis in Alzheimer models

Wei Zhang, Yuewang Yang, Zifei Xiang, Jinping Cheng, Zhijun Yu, Wen Wang, Ling Hu, Fuyun Ma, Youping Deng, Zhigang Jin, Xiamin Hu,

https://doi.org/10.18632/aging.203883 pp 4305—4325

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Sperm DNA integrity is critically impacted by male age but does not influence outcomes of artificial insemination by husband in the Chinese infertile couples

Yumei Luo, Shunhong Wu, Mimi Zhang, Hua Zhou, Jingru Yuan, Yiying Yang, Yufang Zhong, Qing Li, Xiaofang Sun, Xia Xu, Detu Zhu,

https://doi.org/10.18632/aging.204058 pp 4326—4335

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Identification and validation of aging-related genes in COPD based on bioinformatics analysis

Shan Zhong, Li Yang, Naijia Liu, Guangkeng Zhou, Zhangli Hu, Chengshui Chen, Yun Wang,

https://doi.org/10.18632/aging.204064 pp 4336—4356

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Glioblastoma: two immune subtypes under the surface of the cold tumor

Wu Xiong, Cong Li, Guang Kong, Bowen Wan, Siming Wang, Jin Fan,

https://doi.org/10.18632/aging.204067 pp 4357—4375

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CircRNA has_circ_0069313 induced OSCC immunity escape by miR-325-3p-Foxp3 axes in both OSCC cells and Treg cells

Yiyang Chen, Zeyu Li, Jianfeng Liang, Jiayu Liu, Jiansuo Hao, Quan Wan, Jiameng Liu, Chongdai Luo, Zhiyuan Lu,

https://doi.org/10.18632/aging.204068 pp 4376—4389

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Exercise intervention prevents early aged hypertension-caused cardiac dysfunction through inhibition of cardiac fibrosis

Yi Hong, Ai-Lun Yang, James K.S. Wong, Kunanya Masodsai, Shin-Da Lee, Yi-Yuan Lin,

https://doi.org/10.18632/aging.204077 pp 4390—4401

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Intra-tumoral angiogenesis correlates with immune features and prognosis in glioma

Qing Zhang, Yao-Xing Guo, Wan-Lin Zhang, Hai-Yan Lian, Natasha Iranzad, Endi Wang, Ying-Chun Li, Hai-Chao Tong, Le-Yao Li, Ling-Yun Dong, Lian-He Yang, Shuang Ma,

https://doi.org/10.18632/aging.204079 pp 4402—4424

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Transcriptional ITPR3 as potential targets and biomarkers for human pancreatic cancer

Wangyang Zheng, Xue Bai, Yongxu Zhou, Liang Yu, Daolin Ji, Yuling Zheng, Nanfeng Meng, Hang Wang, Ziyue Huang, Wangming Chen, Judy Wai Ping Yam, Yi Xu, Yunfu Cui,

https://doi.org/10.18632/aging.204080 pp 4425—4444

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A real-time pluripotency reporter for the long-term and real-time monitoring of pluripotency changes in induced pluripotent stem cells

Hong-Fen Shen, Yong-Long Li, Shi-Hao Huang, Jia-Wei Xia, Zhi-Fang Yao, Gao-Fang Xiao, Ying Zhou, Ying-Chun Li, Jun-Wen Shi, Xiao-Lin Lin, Wen-Tao Zhao, Yan Sun, Yu-Guang Tian, Jun-Shuang Jia, Dong Xiao,

https://doi.org/10.18632/aging.204083 pp 4445—4458

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Are beta blockers effective in preventing stroke-associated infections? - a systematic review and meta-analysis

Li Yang, Xiang Wenping, Zhang Jinfeng, Pang Jiangxia, Wang Jingbo, Wang Baojun,

https://doi.org/10.18632/aging.204086 pp 4459—4470

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NcRNAs-mediated P2RX1 expression correlates with clinical outcomes and immune infiltration in patients with breast invasive carcinoma

Yiyue Xu, Bing Zou, Bingjie Fan, Butuo Li, Jinming Yu, Linlin Wang, Jin Zhang,

https://doi.org/10.18632/aging.204087 pp 4471—4485

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Long noncoding RNA KCNQ1OT1 inhibits osteoclast differentiation by regulating the miR-128-3p/NFAT5 axis

Hengshuo Zhang, Lu Chen, Ziyu Wang, Zhenqian Sun, Yu Shan, Qinghui Li, Linzeng Qi, Hongliang Wang, Yunzhen Chen,

https://doi.org/10.18632/aging.204088 pp 4486—4499

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Combined impacts of histamine receptor H1 gene polymorphisms and an environmental carcinogen on the susceptibility to and progression of oral squamous cell carcinoma

Yi-Fang Ding, Yung-Wei Lin, Wen-Kuan Chiu, Chiao-Wen Lin, Yi-Chieh Yang, Lun-Ching Chang, Jungshan Chang, Shun-Fa Yang, Ming-Hsien Chien,

https://doi.org/10.18632/aging.204089 pp 4500—4512

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The bioinformatics and experimental analysis of the novel roles of virus infection-associated gene CDC20 for prognosis and immune infiltration in hepatocellular carcinoma

Juanni Li, Xiaofang Zhang, Lei Yao, Kuan Hu,

https://doi.org/10.18632/aging.204093 pp 4513—4529

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Identification of hub biomarkers and immune cell infiltration in polymyositis and dermatomyositis

Si Chen, Haolong Li, Haoting Zhan, Xiaoli Zeng, Hui Yuan, Yongzhe Li,

https://doi.org/10.18632/aging.204098 pp 4530—4555

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The impact of ALDH7A1 variants in oral cancer development and prognosis

Hsueh-Ju Lu, Chun-Yi Chuang, Mu-Kuan Chen, Chun-Wen Su, Wei-En Yang, Chia-Ming Yeh, Kuan-Ming Lai, Chih-Hsin Tang, Chiao-Wen Lin, Shun-Fa Yang,

https://doi.org/10.18632/aging.204099 pp 4556—4571

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Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis

Xiao-Bo Zhang, Si-Qi Xu, Yi-Geng Hui, Hai-Yu Zhou, Yi-Cun Hu, Rui-Hao Zhang, Xi-Dan Gao, Chang-Ming Zheng,

https://doi.org/10.18632/aging.204100 pp 4572—4585

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers

Xiaofan Su, Haoxuan Jin, Jiaqian Wang, Huiping Lu, Tiantian Gu, Zhibo Gao, Manxiang Li,

https://doi.org/10.18632/aging.204101 pp 4586—4605

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Comprehensive analysis of expression profiles and prognosis of TRIM genes in human kidney clear cell carcinoma

Junwen Shen, Rongjiang Wang, Yu Chen, Zhihai Fang, Jianer Tang, Jianxiang Yao, Jianguo Gao, Wenxia Zhou, Xiongnong Chen,

https://doi.org/10.18632/aging.204102 pp 4606—4617

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