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Page: 1234 of 4

• Theory ArticleVolume 10, Issue 10pp 2557-2569

  Aging and aging-associated diseases: a microRNA-based endocrine regulation hypothesis

  Relevance score: 0.00

  Samuil Umansky

  Keywords: geroscience, miRNA hormones, pituitary gland, sex-dependent differences, degeneration and carcinogenesis, Down syndrome

  Published in Aging on October 29, 2018

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• Research PaperVolume 9, Issue 10pp 2190-2208

  Degeneration of the osteocyte network in the C57BL/6 mouse model of aging

  Relevance score: 0.00

  LeAnn M. Tiede-Lewis, Yixia Xie, Molly A. Hulbert, Richard Campos, Mark R. Dallas, Vladimir Dusevich, Lynda F. Bonewald, Sarah L. Dallas

  Keywords: aging, osteocytes, osteoporosis, dendrite degeneration, bone fragility

  Published in Aging on October 26, 2017

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• EditorialVolume 14, Issue 12pp 4933-4934

  Heavy lipids protect against heavy metals

  Relevance score: 0.00

  Joshua L. Dunaief

  Keywords: macular degeneration, AMD, oxidative stress, anti-oxidant, drug

  Published in Aging on June 22, 2022

• Research PaperVolume 17, Issue 9pp 2369-2391

  Runx1 overexpression induces early onset of intervertebral disc degeneration

  Relevance score: 0.00

  Takanori Fukunaga, Martha Elena Diaz-Hernandez, John G. Heller, Changli Zhang, Hicham Drissi

  Keywords: cell senescence, aging, Runx1, nucleus pulposus, intervertebral disc degeneration

  Published in Aging on September 8, 2025

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• Research PaperVolume 16, Issue 12pp 10216-10238

  Oxidative stress-induced EGR1 upregulation promotes NR4A3-mediated nucleus pulposus cells apoptosis in intervertebral disc degeneration

  Relevance score: 0.00

  Si-Kuan Zheng, Xiao-Kun Zhao, Hui Wu, Ding-Wen He, Long Xiong, Xi-Gao Cheng

  Keywords: intervertebral disc degeneration, EGR1, NR4A3, nucleus pulposus, apoptosis

  Published in Aging on June 28, 2024

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• RetractionVolume 16, Issue 10pp 9305-9305

  Retraction for: DNMT3B decreases extracellular matrix degradation and alleviates intervertebral disc degeneration through TRPA1 methylation to inhibit the COX2/YAP axis

  Relevance score: 0.00

  Zhiqiang Luo, Yanchao Ma, Tianning Di, Bing Ma, Hongwei Li, Jiangdong An, Yonggang Wang, Haihong Zhang

  Keywords: intervertebral disc degeneration, nucleus pulposus, extracellular matrix, inflammation, DNA methyltransferase

  Published in Aging on May 31, 2024

• Research PaperVolume 16, Issue 9pp 8044-8069

  Bioinformatics analysis for constructing a cellular senescence-related age-related macular degeneration diagnostic model and identifying relevant disease subtypes to guide treatment

  Relevance score: 0.00

  Shan Luo, Qiang Hu, Bo Jiang, Zhongyu Zhang, Dawei Sun

  Keywords: age-related macular degeneration, cellular senescence, programmed cell death, inflammatory response, molecular subtypes

  Published in Aging on May 10, 2024

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• Research PaperVolume 16, Issue 6pp 5050-5064

  Omilancor mitigates the senescence of nucleus pulposus cells induced by DDP through targeting MAP2K6

  Relevance score: 0.00

  Fang Yafeng, Shi Xinpeng, Wei Rong, Cui Guofeng

  Keywords: intervertebral disc degeneration, Omilancor, cellular senescence, MAP2K6

  Published in Aging on March 20, 2024

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• Research PaperVolume 16, Issue 6pp 5370-5386

  Comprehensive analysis of gene expression profiles of annulus fibrosus subtypes and hub genes in intervertebral disc degeneration

  Relevance score: 0.00

  Xiaokun Zhao, Jian Zhang, Jiahao Liu, Jinghong Yuan, Tianlong Wu, Xigao Cheng

  Keywords: intervertebral disc degeneration, annulus fibrosus, molecular subtype, WGCNA, machine learning

  Published in Aging on March 13, 2024

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• Research PaperVolume 16, Issue 2pp 1145-1160

  Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation

  Relevance score: 0.00

  Baining Zhang, Zhiwei He, Jialin Guo, Feng Li, Zhi Huang, Wenkai Zheng, Wenhua Xing, Manglai Li, Yong Zhu, Xuejun Yang

  Keywords: Sesamin, BECN2, cartilage endplate degeneration, autophagy, inflammation

  Published in Aging on January 26, 2024

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• Research PaperVolume 15, Issue 24pp 15599-15623

  Unravelling diagnostic clusters and immune landscapes of cuproptosis patterns in intervertebral disc degeneration through dry and wet experiments

  Relevance score: 0.00

  Peng Zhang, Jiahui He, Yanchi Gan, Qi Shang, Honglin Chen, Wenhua Zhao, Jianchao Cui, Gengyang Shen, Yuwei Li, Xiaobing Jiang, Guangye Zhu, Hui Ren

  Keywords: intervertebral disc degeneration, cuproptosis biomarkers, subtype classification, immune microenvironment infiltration, experimental validation

  Published in Aging on December 29, 2023

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• Research PaperVolume 15, Issue 24pp 14764-14790

  Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement

  Relevance score: 0.00

  Yingjing Zhao, Yuxue Mu, Yujia Zou, Zhijian He, Tianxing Lu, Xinhui Wang, Weihang Li, Bo Gao

  Keywords: intervertebral disc degeneration, weighted gene co-expression network analysis, Janus kinase family, high-throughput virtual screening, single-cell transcriptome

  Published in Aging on December 12, 2023

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• Research PaperVolume 15, Issue 23pp 13693-13709

  The antioxidant Glycitin protects against intervertebral disc degeneration through antagonizing inflammation and oxidative stress in nucleus pulposus cells

  Relevance score: 0.00

  Wei Zhao, Yanpei Li, Xiang Cheng, Hui Wei, Peng Li, Lixia Fan, Kaiwen Liu, Shuai Zhang, Hao Wang

  Keywords: intervertebral disc degeneration, Glycitin, inflammation, TNF-α, ROS

  Published in Aging on November 28, 2023

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• Research PaperVolume 15, Issue 10pp 4288-4303

  DNMT1 regulates polarization of macrophage-induced intervertebral disc degeneration by modulating SIRT6 expression and promoting pyroptosis in vivo

  Relevance score: 0.00

  Yang Hou, Jiangang Shi, Yongfei Guo, Guodong Shi

  Keywords: intervertebral disc degeneration, macrophage polarization, DNA methyltransferase 1, sirtuin 6

  Published in Aging on May 17, 2023

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• Research PaperVolume 15, Issue 6pp 1713-1733

  Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells

  Relevance score: 0.00

  Tu Nguyen, Daniel Urrutia-Cabrera, Luozixian Wang, Jarmon G. Lees, Jiang-Hui Wang, Sandy S.C. Hung, Alex W. Hewitt, Thomas L. Edwards, Sam McLenachan, Fred K. Chen, Shiang Y. Lim, Chi D. Luu, Robyn Guymer, Raymond C.B. Wong

  Keywords: age-related macular degeneration, retina, CRISPR/Cas, mitochondria superoxide, POLDIP2

  Published in Aging on February 16, 2023

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• Research PaperVolume 15, Issue 1pp 37-52

  Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

  Relevance score: 0.00

  Chi-Hsiu Liu, Felix Yemanyi, Kiran Bora, Neetu Kushwah, Alexandra K. Blomfield, Theodore M. Kamenecka, John Paul SanGiovanni, Ye Sun, Laura A. Solt, Jing Chen

  Keywords: age-related macular degeneration, angiogenesis, choroidal neovascularization, inflammation, nuclear receptors, RORα, VEGFR2, TNFα

  Published in Aging on January 10, 2023

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• Research PaperVolume 14, Issue 10pp 4572-4585

  Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis

  Relevance score: 0.00

  Xiao-Bo Zhang, Si-Qi Xu, Yi-Geng Hui, Hai-Yu Zhou, Yi-Cun Hu, Rui-Hao Zhang, Xi-Dan Gao, Chang-Ming Zheng

  Keywords: lactotransferrin, intervertebral disc degeneration, bioinformatics, nucleus pulposus cell, mechanism

  Published in Aging on May 25, 2022

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• Research PaperVolume 13, Issue 24pp 25763-25777

  Retinal drusen in patients with chronic myeloproliferative blood cancers are associated with an increased proportion of senescent T cells and signs of an aging immune system

  Relevance score: 0.00

  Charlotte Liisborg, Vibe Skov, Lasse Kjær, Hans Carl Hasselbalch, Torben Lykke Sørensen

  Keywords: age-related macular degeneration, drusen, myeloproliferative neoplasms, chronic low-grade inflammation, immunosenescence, T cells

  Published in Aging on December 26, 2021

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• Research PaperVolume 13, Issue 19pp 23182-23192

  Decreased gray matter volume and increased white matter volume in patients with neovascular age-related macular degeneration: a voxel-based morphometry study

  Relevance score: 0.00

  Yan-Kun Shen, Qian-Min Ge, Yi-Cong Pan, Hui-Ye Shu, Li-Juan Zhang, Qiu-Yu Li, Rong-Bin Liang, Yi Shao, Yao Yu

  Keywords: neovascular age-related macular degeneration, choroidal neovascularization, mental disorder

  Published in Aging on October 6, 2021

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• Research PaperVolume 13, Issue 18pp 22459-22473

  miR-19b-3p relieves intervertebral disc degeneration through modulating PTEN/PI3K/Akt/mTOR signaling pathway

  Relevance score: 0.00

  Yulin Zhao, Aimin Li

  Keywords: intervertebral disc degeneration, miR-19b-3p, PTEN, apoptosis, signaling pathways

  Published in Aging on September 23, 2021

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