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The cover features Figure 6 " Green tea catechins enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition“ from Tian et al.

Volume 13, Issue 19

15 October, 2021
pp 22625—23434

About the Cover

The cover features Figure 6 " Green tea catechins enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition“ from Tian et al.


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Editorials

Adipokines, cell polarity disruption and breast cancer

Danila Coradini,
https://doi.org/10.18632/aging.203621 pp 22625—22626
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Preventing metastatic emergence of breast cancer

Alan Wells, Colin Beckwitt, Juan Luis Gomez Marti,
https://doi.org/10.18632/aging.203631 pp 22627—22628
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Priority Research Paper

Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition

Jing Tian, Caroline Geiss, Kim Zarse, Corina T. Madreiter-Sokolowski, Michael Ristow,
https://doi.org/10.18632/aging.203597 pp 22629—22648
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Research Papers

Effects of periostin deficiency on kidney aging and lipid metabolism

Jung Nam An, Hyoseon Kim, Eun Nim Kim, Ara Cho, Yeongeun Cho, Young Wook Choi, Jin Hyuk Kim, Seung Hee Yang, Bum Soon Choi, Chun Soo Lim, Yon Su Kim, Kwang Pyo Kim, Jung Pyo Lee,
https://doi.org/10.18632/aging.203580 pp 22649—22665
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Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in mild cognitive impairment: a case-control study

Ted Kheng Siang Ng, Christina Coughlan, Patricia C. Heyn, Alex Tagawa, James J. Carollo, Ee Heok Kua, Rathi Mahendran,
https://doi.org/10.18632/aging.203598 pp 22666—22689
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Circulating CD5L is associated with cardiovascular events and all-cause mortality in individuals with chronic kidney disease

Esmeralda Castelblanco, Maria R. Sarrias, Àngels Betriu, Berta Soldevila, Maria Barranco-Altirriba, Josep Franch-Nadal, Jose M. Valdivielso, Marcelino Bermudez-Lopez, Per-Henrik Groop, Elvira Fernández, Núria Alonso, Didac Mauricio,
https://doi.org/10.18632/aging.203615 pp 22690—22709
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Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model

Gustavo Satoru Kajitani, Lear Brace, Jose Humberto Trevino-Villarreal, Kaspar Trocha, Michael Robert MacArthur, Sarah Vose, Dorathy Vargas, Roderick Bronson, Sarah Jayne Mitchell, Carlos Frederico Martins Menck, James Robert Mitchell,
https://doi.org/10.18632/aging.203617 pp 22710—22731
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The central role of the glutamate metabolism in long-term antiretroviral treated HIV-infected individuals with metabolic syndrome

Marco Gelpi, Flora Mikaeloff, Andreas D. Knudsen, Rui Benfeitas, Shuba Krishnan, Sara Svenssson Akusjärvi, Julie Høgh, Daniel D. Murray, Henrik Ullum, Ujjwal Neogi, Susanne D. Nielsen,
https://doi.org/10.18632/aging.203622 pp 22732—22751
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Exposure to ionizing radiation disrupts normal epigenetic aging in Japanese medaka

Emily M. Bertucci, Marilyn W. Mason, Olin E. Rhodes, Benjamin B. Parrott,
https://doi.org/10.18632/aging.203624 pp 22752—22771
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Immunological age prediction in HIV-infected, ART-treated individuals

Lesley R. de Armas, Suresh Pallikkuth, Li Pan, Stefano Rinaldi, Rajendra Pahwa, Savita Pahwa,
https://doi.org/10.18632/aging.203625 pp 22772—22791
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Identification of hub genes and key pathways of paraquat-induced human embryonic pulmonary fibrosis by bioinformatics analysis and in vitro studies

Xiangxia Zeng, Jinlun Hu, Mei Yan, Chunming Xie, Weigan Xu, Qiaohua Hu, Jinxia Feng, Zi Cong Gu, Yue Fu,
https://doi.org/10.18632/aging.203570 pp 22792—22801
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Highly expressed centromere protein L indicates adverse survival and associates with immune infiltration in hepatocellular carcinoma

Zhili Zeng, Xiao Jiang, Zhibin Pan, Ruisheng Zhou, Zhuangteng Lin, Ying Tang, Ying Cui, Enxin Zhang, Zebiao Cao,
https://doi.org/10.18632/aging.203574 pp 22802—22829
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Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer

Xuhui Fan, Haotian Fu, Ni Xie, Hangcheng Guo, Tiantian Fu, Yunfeng Shan,
https://doi.org/10.18632/aging.203575 pp 22830—22842
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Allicin protects against myocardial I/R by accelerating angiogenesis via the miR-19a-3p/PI3K/AKT axis

Mengru Liu, Peng Yang, Dongliang Fu, Tong Gao, Xinyi Deng, Mingjing Shao, Jiangquan Liao, Hong Jiang, Xianlun Li,
https://doi.org/10.18632/aging.203578 pp 22843—22855
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Retrospective analysis of renal prognosis in elderly coronary artery disease patients complicated with renal insufficiency

Jun Li, Fa-Hu Liu, Jing Guo, Ya-Fen Yu, Chun-Qing Li,
https://doi.org/10.18632/aging.203579 pp 22856—22866
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Computational study of effective matrix metalloproteinase 9 (MMP9) targeting natural inhibitors

Naimeng Liu, Xinhui Wang, Hao Wu, Xiaye Lv, Haoqun Xie, Zhen Guo, Jing Wang, Gaojing Dou, Chenxi Zhang, Mindan Sun,
https://doi.org/10.18632/aging.203581 pp 22867—22882
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Transcriptome study of oleanolic acid in the inhibition of breast tumor growth based on high-throughput sequencing

Zhuoran Liang, Ruolan Pan, Xia Meng, Jinxing Su, Yong Guo, Gang Wei, Zhi Zhang, Kan He,
https://doi.org/10.18632/aging.203582 pp 22883—22897
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Downregulation of KIF2C and TEKT2 is associated with male infertility and testicular carcinoma

Haiming Cao, Zi Wan, Fei Wang, Ziyin Liu, Xiaofeng Li, Jianquan Hou,
https://doi.org/10.18632/aging.203583 pp 22898—22911
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Significance of CD8+ T cell infiltration-related biomarkers and the corresponding prediction model for the prognosis of kidney renal clear cell carcinoma

Yuan Tian, Yumei Wei, Hongmei Liu, Heli Shang, Yuedong Xu, Tong Wu, Wei Liu, Alan Huang, Qi Dang, Yuping Sun,
https://doi.org/10.18632/aging.203584 pp 22912—22933
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Agomelatine might be more appropriate for elderly, depressed, type 2 diabetes mellitus patients than paroxetine/fluoxetine

Zihong Liang, Yanbo Jia, Lizhen Zhao, Runxiu Zhu, Xuemei He, Bagen Tong, Fan Yang, Lixia Hao, Pengfei Cui, Jun Yuan,
https://doi.org/10.18632/aging.203586 pp 22934—22946
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A novel prognostic signature based on immune-related genes of diffuse large B-cell lymphoma

Zizheng Wu, Qingpei Guan, Xue Han, Xianming Liu, Lanfang Li, Lihua Qiu, Zhengzi Qian, Shiyong Zhou, Xianhuo Wang, Huilai Zhang,
https://doi.org/10.18632/aging.203587 pp 22947—22962
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RUNX2 and LAMC2: promising pancreatic cancer biomarkers identified by an integrative data mining of pancreatic adenocarcinoma tissues

Guihua Jin, Qingqing Ruan, Fugen Shangguan, Linhua Lan,
https://doi.org/10.18632/aging.203589 pp 22963—22984
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Vitellogenin 2 promotes muscle development and stimulates the browning of white fat

Yilei Li, Xiaoli Sun, Yun Bai, Yunyan Ji, Huawei Ren, Xiuju Yu, Yi Yan, Xiaoyan He, Yanjun Dong, Liping Zhang, Xiaomao Luo, Haidong Wang,
https://doi.org/10.18632/aging.203590 pp 22985—23003
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lncRNA MEG3 aggravated neuropathic pain and astrocyte overaction through mediating miR-130a-5p/CXCL12/CXCR4 axis

Jiacai Dong, Rui Xia, Zhonggui Zhang, Cheng Xu,
https://doi.org/10.18632/aging.203592 pp 23004—23019
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DCP1A is an unfavorable prognostic-related enhancer RNA in hepatocellular carcinoma

Hao Wu, Jinrui Zhang, Yi Bai, Sai Zhang, Zhixin Zhang, Wen Tong, Pinsheng Han, Bing Fu, Yamin Zhang, Zhongyang Shen,
https://doi.org/10.18632/aging.203593 pp 23020—23035
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Low expression of endoplasmic reticulum stress-related gene SERP1 is associated with poor prognosis and immune infiltration in skin cutaneous melanoma

Yuchao Fan, Xiao Liang, Deshui Yu,
https://doi.org/10.18632/aging.203594 pp 23036—23071
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Establishment of a novel ferroptosis-related lncRNA pair prognostic model in colon adenocarcinoma

Hong Li, Lili Liu, Tianyi Huang, Ming Jin, Zhen Zheng, Hui Zhang, Meng Ye, Kaitai Liu,
https://doi.org/10.18632/aging.203599 pp 23072—23095
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Zhoushi Qi Ling decoction represses docetaxel resistance and glycolysis of castration-resistant prostate cancer via regulation of SNHG10/miR-1271-5p/TRIM66 axis

Hongwen Cao, Dan Wang, Peng Sun, Lei Chen, Yigeng Feng, Renjie Gao,
https://doi.org/10.18632/aging.203602 pp 23096—23107
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METTL3 regulates hippocampal gene transcription via N6-methyladenosine methylation in sevoflurane-induced postoperative cognitive dysfunction mouse

Baiqing He, Jian Wang,
https://doi.org/10.18632/aging.203604 pp 23108—23118
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Ribosome profiling reveals translatome remodeling in cancer cells in response to zinc oxide nanoparticles

Saisai Wei, Wenhao Guo, Yu Qian, Jie Xiang, Kangli Liu, Xiang-Jing Gao, Xiangwei Gao, Yicheng Chen,
https://doi.org/10.18632/aging.203606 pp 23119—23132
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Short-term high-fat diet favors the appearances of apoptosis and gliosis by activation of ERK1/2/p38MAPK pathways in brain

Chao-Jin Xu, Mei-Qi Li, Li-Zhao, Wei-Guang Chen, Jun-Ling Wang,
https://doi.org/10.18632/aging.203607 pp 23133—23148
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Comprehensive analysis of aberrant alternative splicing related to carcinogenesis and prognosis of papillary thyroid cancer

Xiaobo Zheng, Li Feng, Yunfan Yin, Chune Yu, Xiujing He, Jiao Zhu, Ming Zhang, Jing Yu, Mingqing Xu,
https://doi.org/10.18632/aging.203608 pp 23149—23168
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LncRNA-SNHG1 promotes macrophage M2-like polarization and contributes to breast cancer growth and metastasis

Shoukai Zong, Wei Dai, Xiangting Guo, Kai Wang,
https://doi.org/10.18632/aging.203609 pp 23169—23181
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Decreased gray matter volume and increased white matter volume in patients with neovascular age-related macular degeneration: a voxel-based morphometry study

Yan-Kun Shen, Qian-Min Ge, Yi-Cong Pan, Hui-Ye Shu, Li-Juan Zhang, Qiu-Yu Li, Rong-Bin Liang, Yi Shao, Yao Yu,
https://doi.org/10.18632/aging.203610 pp 23182—23192
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Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial cells injury of colitis through regulating pyroptosis by AMPK/Nrf2/NLRP3 inflammasome

Weiwei Zhang, Wusan Wang, Chaozhuang Shen, Xiaohu Wang, Zhichen Pu, Qin Yin,
https://doi.org/10.18632/aging.203611 pp 23193—23209
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Integrated analysis of tumor-associated macrophage infiltration and prognosis in ovarian cancer

Qianxia Tan, Huining Liu, Jie Xu, Yanqun Mo, Furong Dai,
https://doi.org/10.18632/aging.203613 pp 23210—23232
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Long non-coding RNA CRNDE as potential biomarkers facilitate inflammation and apoptosis in alcoholic liver disease

Yifeng Yan, Liang Ren, Yan Liu, Liang Liu,
https://doi.org/10.18632/aging.203614 pp 23233—23244
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Identification of potential target genes of non-small cell lung cancer in response to resveratrol treatment by bioinformatics analysis

Peng Gao, Guanghui Ren,
https://doi.org/10.18632/aging.203616 pp 23245—23261
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Whole-exome sequencing of rectal cancer identifies locally recurrent mutations in the Wnt pathway

Yi Yang, Xiaodong Gu, Zhenyang Li, Chuang Zheng, Zihao Wang, Minwei Zhou, Zongyou Chen, Mengzhen Li, Dongbing Li, Jianbin Xiang,
https://doi.org/10.18632/aging.203618 pp 23262—23283
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Transcriptome research identifies four hub genes related to primary myelofibrosis: a holistic research by weighted gene co-expression network analysis

Weihang Li, Yingjing Zhao, Dong Wang, Ziyi Ding, Chengfei Li, Bo Wang, Xiong Xue, Jun Ma, Yajun Deng, Quancheng Liu, Guohua Zhang, Ying Zhang, Kai Wang, Bin Yuan,
https://doi.org/10.18632/aging.203619 pp 23284—23307
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Transcriptome and proteome analysis of the antitumor activity of maslinic acid against pancreatic cancer cells

Hewei Zhang, Lijun Kong, Yan Zhang, Cheng Wang, Linxiao Sun,
https://doi.org/10.18632/aging.203623 pp 23308—23327
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Effects of Yu Linzhu on ovarian function and oocyte mitochondria in natural aging mice

Zhen Yang, Mao-Lin Wei, Xiao-Ying Dong,
https://doi.org/10.18632/aging.203626 pp 23328—23337
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A novel mutation in PCK2 gene causes primary angle-closure glaucoma

Menghan Xu, Jin Yang, Jiayue Sun, Xuemei Xing, Zheng Liu, Tao Liu,
https://doi.org/10.18632/aging.203627 pp 23338—23347
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Differential moderation effects of ApoE and 5-HTTLPR genotypes on social vulnerability in predicting mortality among community-dwelling middle-aged and older adults: a nationwide population-based study

Hsin-Yu Liu, Li-Ning Peng, Wei-Ju Lee, Ming-Yueh Chou, Chih-Kuang Liang, Fei-Yuan Hsiao, Ming-Hsien Lin, Liang-Kung Chen,
https://doi.org/10.18632/aging.203629 pp 23348—23360
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piRNA-36741 regulates BMP2-mediated osteoblast differentiation via METTL3 controlled m6A modification

Jianmin Liu, Ming Chen, Longyang Ma, Xingbo Dang, Gongliang Du,
https://doi.org/10.18632/aging.203630 pp 23361—23375
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Potentiated lung adenocarcinoma (LUAD) cell growth, migration and invasion by lncRNA DARS-AS1 via miR-188-5p/ KLF12 axis

Yangyang Liu, Lu Liang, Liang Ji, Fuquan Zhang, Donglai Chen, Shanzhou Duan, Hao Shen, Yao Liang, Yongbing Chen,
https://doi.org/10.18632/aging.203632 pp 23376—23392
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Cosmc transfection decreases malignant behavior of Tn+ cells and enhances sensitivity to apoptosis when induced by Apo2L/TRAIL via alteration of O-glycan structure

Ruisong Ding, Xingyou Hu, Wen Hu, Zhenzhen Du, Panpan Huang, Mengyang Wang, Jiaoyue Sheng, Yanchao Ma, Ailing Wang, Xiying Luan, Menghua Dong, Qizhi Cao, Yanfen Zou, Tao Hu,
https://doi.org/10.18632/aging.203633 pp 23393—23406
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Theory Article

Iron: an underrated factor in aging

Dennis Mangan,
https://doi.org/10.18632/aging.203612 pp 23407—23415
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Review

Impact of aging on primary liver cancer: epidemiology, pathogenesis and therapeutics

Rocio I.R. Macias, Maria J. Monte, Maria A. Serrano, Jesús M. González-Santiago, Isabel Martín-Arribas, André L. Simão, Rui E. Castro, Javier González-Gallego, José L. Mauriz, Jose J.G. Marin,
https://doi.org/10.18632/aging.203620 pp 23416—23434
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