Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

Volume 14, Issue 12

30 June, 2022
pp 4929—5291

About the Cover

The cover features Figure 4 " Chromatin state definition and transitions between states with age" from Hillje et al.

Explore This Issue

Editorials

Janus-faced citrate in aging and metabolism

Wei-Sheng Lin, Pei-Yu Wang,

https://doi.org/10.18632/aging.204138 pp 4929—4930

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Translating bone marrow rejuvenation from the bench to bedside

Faisal J. Alibhai, Ren-Ke Li,

https://doi.org/10.18632/aging.204142 pp 4931—4932

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Heavy lipids protect against heavy metals

Joshua L. Dunaief,

https://doi.org/10.18632/aging.204143 pp 4933—4934

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Research Papers

Optimizing future well-being with artificial intelligence: self-organizing maps (SOMs) for the identification of islands of emotional stability

Fedor Galkin, Kirill Kochetov, Michelle Keller, Alex Zhavoronkov, Nancy Etcoff,

https://doi.org/10.18632/aging.204061 pp 4935—4958

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Time makes histone H3 modifications drift in mouse liver

Roman Hillje, Lucilla Luzi, Stefano Amatori, Giuseppe Persico, Francesca Casciaro, Martina Rusin, Mirco Fanelli, Piergiuseppe Pelicci, Marco Giorgio,

https://doi.org/10.18632/aging.204107 pp 4959—4975

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Differential impact of glycemic control and comorbid conditions on the neurophysiology underlying task switching in older adults with type 2 diabetes

Christine M. Embury, Grace H. Lord, Andjela T. Drincic, Cyrus V. Desouza, Tony W. Wilson,

https://doi.org/10.18632/aging.204129 pp 4976—4989

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Sus1 maintains a normal lifespan through regulation of TREX-2 complex-mediated mRNA export

Suji Lim, Yan Liu, Byung-Ho Rhie, Chun Kim, Hong-Yeoul Ryu, Seong Hoon Ahn,

https://doi.org/10.18632/aging.204146 pp 4990—5012

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Huangqi Guizhi Wuwu Decoction can prevent and treat oxaliplatin-induced neuropathic pain by TNFα/IL-1β/IL-6/MAPK/NF-kB pathway

Mingzhu Li, Zheng Li, Xiande Ma, Shengbo Jin, Yang Cao, Xuebing Wang, Jian Zhao, Jianbo Wang, Xin Wang, Jian Xu,

https://doi.org/10.18632/aging.203794 pp 5013—5022

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Nomogram predicting leukopenia in osteosarcoma after high-dose methotrexate chemotherapy

Haixiao Wu, Guijun Xu, Zhijun Li, Yao Xu, Yile Lin, Vladimir P. Chekhonin, Karl Peltzer, Jun Wang, Shu Li, Huiyang Li, Jin Zhang, Yuan Xue, Wenjuan Ma, Xin Wang, Chao Zhang,

https://doi.org/10.18632/aging.203978 pp 5023—5033

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Multi-omics analysis reveals the panoramic picture of necroptosis-related regulators in pan-cancer

Guanghao Li, Xiaoxuan Wang, Yongheng Liu, Huikai Li, Han Mu, Yanting Zhang, Qiang Li,

https://doi.org/10.18632/aging.204124 pp 5034—5058

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The circular RNA hsa_circ_0003091 regulates sepsis-induced lung injury by sponging the miR-149/Smad2 axis

Mei-Jia Shen, Shen-Tao Yan, Xiao-Yan Zhang, Wen Li, Xu Chen, Xiao-Xiao Zheng, Guo-Qiang Zhang, Li-Chao Sun,

https://doi.org/10.18632/aging.204125 pp 5059—5074

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The minor allele of rs17427875 in long non-coding RNA-HOXA11-AS influences the prognosis of subarachnoid hemorrhage (SAH) via modulating miR-15a and STAT3 expression

Yong Zhou, Zhiming Xu, Shengli Li,

https://doi.org/10.18632/aging.204126 pp 5075—5085

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Galectin-3 induces vascular smooth muscle cells calcification via AMPK/TXNIP pathway

Lei Tian, Yong Wang, Ruiyan Zhang,

https://doi.org/10.18632/aging.204130 pp 5086—5096

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Calreticulin nuclear translocalization alleviates CaM/CaMKII/CREB signaling pathway to enhance chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells

Yi-Sheng Liu, Yu-Chun Chang, Wei-Wen Kuo, Ming-Cheng Chen, Tso-Fu Wang, Tung-Sheng Chen, Yueh-Min Lin, Chi-Cheng Li, Po-Hsiang Liao, Chih-Yang Huang,

https://doi.org/10.18632/aging.204131 pp 5097—5115

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Risk of dialysis in patients receiving intravitreal anti–vascular endothelial growth factor treatment: a population-based cohort study

Shun-Fa Yang, Yu-Chen Su, Chen-Chee Lim, Jing-Yang Huang, Sheng-Min Hsu, Li-Wha Wu, Yi-Sheng Chang, Jia-Horung Hung,

https://doi.org/10.18632/aging.204133 pp 5116—5130

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Exploring immune-related signatures for predicting immunotherapeutic responsiveness, prognosis, and diagnosis of patients with colon cancer

Lichao Cao, Ying Ba, Jin Yang, Hezi Zhang,

https://doi.org/10.18632/aging.204134 pp 5131—5152

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Long non-coding RNA NUT family member 2A-antisense RNA 1 sponges microRNA-613 to increase the resistance of gastric cancer cells to matrine through regulating oxidative stress and vascular endothelial growth factor A

Haifeng Ying, Yinchun Jin, Yuanbiao Guo, Qiong Li, Ming Ruan, Wenhua Zhu, Chen Yang, Qinyu Li, Lan Zheng,

https://doi.org/10.18632/aging.204135 pp 5153—5162

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Differential gene expression orchestrated by transcription factors in osteoporosis: bioinformatics analysis of associated polymorphism elaborating functional relationships

Chih-Chien Wang, Jen-Jie Weng, Hsiang-Cheng Chen, Meng-Chang Lee, Pi-Shao Ko, Sui-Lung Su,

https://doi.org/10.18632/aging.204136 pp 5163—5176

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LncRNA PEG11as silencing sponges miR-874-3p to alleviate cerebral ischemia stroke via regulating autophagy in vivo and in vitro

Xiamin Hu, Fuyun Ma, Zhongliang Cheng, Suyou Zeng, Ruling Shen, Xuan Li, Junqi Hu, Zhigang Jin, Jinping Cheng,

https://doi.org/10.18632/aging.204140 pp 5177—5194

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POC1A, prognostic biomarker of immunosuppressive microenvironment in cancer

Qi Zhao, Shuping Gao, Xin Chen, Xiyan Zhu,

https://doi.org/10.18632/aging.204141 pp 5195—5210

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DNA methylation-regulated SNX20 overexpression correlates with poor prognosis, immune cell infiltration, and low-grade glioma progression

Xi Chen, Xiulin Jiang, Heping Wang, Chunyan Wang, Chenyang Wang, Chenglong Pan, Fan Zhou, Jintao Tian, Xiaoqun Niu, Zhi Nie, Wei Chen, Xiaobin Huang, Jun Pu, Chen Li,

https://doi.org/10.18632/aging.204144 pp 5211—5222

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The efficacy of adding hyperthermia to the treatment of advanced NSCLC patients based on the states of EGFR

Yanhua Zhou, Qiulu Zhong, Dongning Huang, Li Qin, Jian Huang, Chunhui Wang, Binglin Chen, Menghua Chen, Yihe Li, Wenqi Liu,

https://doi.org/10.18632/aging.204148 pp 5223—5232

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Identification of m7G-associated lncRNA prognostic signature for predicting the immune status in cutaneous melanoma

Jielin Rong, Hui Wang, Yi Yao, Zhengyuan Wu, Leilei Chen, Chaojie Jin, Zhaoyang Shi, Cheng Wu, Xueqing Hu,

https://doi.org/10.18632/aging.204151 pp 5233—5249

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TRPM7 via calcineurin/NFAT pathway mediates metastasis and chemotherapeutic resistance in head and neck squamous cell carcinoma

Tsung-Ming Chen, Chih-Ming Huang, Ming-Shou Hsieh, Chun-Shu Lin, Wei-Hwa Lee, Chi-Tai Yeh, Shao-Cheng Liu,

https://doi.org/10.18632/aging.204154 pp 5250—5270

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Molecular subtypes, prognostic and immunotherapeutic relevant gene signatures mediated by DNA methylation regulators in hepatocellular carcinoma

Rongfeng Shi, Hui Zhao, Suming Zhao, Hongxin Yuan,

https://doi.org/10.18632/aging.204155 pp 5271—5291

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