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• Research PaperVolume 16, Issue 9pp 8044-8069

  Bioinformatics analysis for constructing a cellular senescence-related age-related macular degeneration diagnostic model and identifying relevant disease subtypes to guide treatment

  Relevance score: 0.00

  Shan Luo, Qiang Hu, Bo Jiang, Zhongyu Zhang, Dawei Sun

  Keywords: age-related macular degeneration, cellular senescence, programmed cell death, inflammatory response, molecular subtypes

  Published in Aging on May 10, 2024

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• Research PaperVolume 15, Issue 6pp 1713-1733

  Knockout of AMD-associated gene POLDIP2 reduces mitochondrial superoxide in human retinal pigment epithelial cells

  Relevance score: 0.00

  Tu Nguyen, Daniel Urrutia-Cabrera, Luozixian Wang, Jarmon G. Lees, Jiang-Hui Wang, Sandy S.C. Hung, Alex W. Hewitt, Thomas L. Edwards, Sam McLenachan, Fred K. Chen, Shiang Y. Lim, Chi D. Luu, Robyn Guymer, Raymond C.B. Wong

  Keywords: age-related macular degeneration, retina, CRISPR/Cas, mitochondria superoxide, POLDIP2

  Published in Aging on February 16, 2023

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• Research PaperVolume 15, Issue 1pp 37-52

  Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

  Relevance score: 0.00

  Chi-Hsiu Liu, Felix Yemanyi, Kiran Bora, Neetu Kushwah, Alexandra K. Blomfield, Theodore M. Kamenecka, John Paul SanGiovanni, Ye Sun, Laura A. Solt, Jing Chen

  Keywords: age-related macular degeneration, angiogenesis, choroidal neovascularization, inflammation, nuclear receptors, RORα, VEGFR2, TNFα

  Published in Aging on January 10, 2023

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• Research PaperVolume 13, Issue 24pp 25763-25777

  Retinal drusen in patients with chronic myeloproliferative blood cancers are associated with an increased proportion of senescent T cells and signs of an aging immune system

  Relevance score: 0.00

  Charlotte Liisborg, Vibe Skov, Lasse Kjær, Hans Carl Hasselbalch, Torben Lykke Sørensen

  Keywords: age-related macular degeneration, drusen, myeloproliferative neoplasms, chronic low-grade inflammation, immunosenescence, T cells

  Published in Aging on December 26, 2021

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• Research PaperVolume 13, Issue 9pp 12359-12377

  Intravitreal injection of anti-miRs against miR-142-3p reduces angiogenesis and microglia activation in a mouse model of laser-induced choroidal neovascularization

  Relevance score: 0.00

  Quentin Roblain, Thomas Louis, Cassandre Yip, Louis Baudin, Ingrid Struman, Vincenza Caolo, Vincent Lambert, Julie Lecomte, Agnès Noël, Stephane Heymans

  Keywords: miR-142-3p, age-related macular degeneration, angiogenesis, inflammation, microglia

  Published in Aging on May 5, 2021

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• Research PaperVolume 13, Issue 8pp 10866-10890

  Pharmacologic activation of autophagy without direct mTOR inhibition as a therapeutic strategy for treating dry macular degeneration

  Relevance score: 0.00

  Qitao Zhang, Feriel Presswalla, Robin R. Ali, David N. Zacks, Debra A. Thompson, Jason ML. Miller

  Keywords: age-related macular degeneration (AMD), drusen, lipofuscin, retinal pigment epithelium (RPE), autophagy

  Published in Aging on April 19, 2021

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• Research PaperVolume 12, Issue 24pp 24836-24852

  miR-106b suppresses pathological retinal angiogenesis

  Relevance score: 0.00

  Catherine Ménard, Ariel M. Wilson, Agnieszka Dejda, Khalil Miloudi, François Binet, Sergio Crespo-Garcia, Célia Parinot, Frédérique Pilon, Rachel Juneau, Elisabeth MMA Andriessen, Gaëlle Mawambo, John Paul SanGiovanni, Vincent De Guire, Przemyslaw Sapieha

  Keywords: age related macular degeneration, miR-106b, PERK, choroidal neovascularization, angiogenesis

  Published in Aging on December 23, 2020

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• Research PaperVolume 12, Issue 14pp 13905-13923

  Activation of C-reactive protein proinflammatory phenotype in the blood retinal barrier in vitro: implications for age-related macular degeneration

  Relevance score: 0.00

  Sara Romero-Vázquez, Alfredo Adán, Marc Figueras-Roca, Victor Llorenç, Mark Slevin, Gemma Vilahur, Lina Badimon, Andrew D Dick, Blanca Molins

  Keywords: age-related macular degeneration, retinal pigment epithelium, inflammation, C-reactive protein

  Published in Aging on July 16, 2020

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• Research PaperVolume 11, Issue 17pp 6691-6713

  PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

  Relevance score: 0.00

  Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney

  Keywords: age-related macular degeneration (AMD), RPE, PGC-1α, mitochondria, FDA-approved drugs

  Published in Aging on September 2, 2019

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• Research PaperVolume 10, Issue 12pp 4241-4247

  Circulating insulin-like growth factor-1: a new clue in the pathogenesis of age-related macular degeneration

  Relevance score: 0.00

  Niccolò Castellino, Antonio Longo, Teresio Avitabile, Andrea Russo, Matteo Fallico, Vincenza Bonfiglio, Mario Damiano Toro, Robert Rejdak, Katarzyna Nowomiejska, Paolo Murabito, Claudio Furino, Michele Reibaldi

  Keywords: age‐related macular degeneration, neovascular AMD, IGF-1, anti‐VEGF, senescence, somatomedin C

  Published in Aging on December 29, 2018

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• Research ArticleVolume 8, Issue 9pp 1952-1978

  PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration

  Relevance score: 0.00

  Mayur Choudhary, Jin-dong Ding, Xiaoping Qi, Michael E. Boulton, Pei-Li Yao, Jeffrey M. Peters, Goldis Malek

  Keywords: age-related macular degeneration, PPARβ/δ, nuclear receptors, inflammation, angiogenesis, choroidal neovascularization

  Published in Aging on September 8, 2016

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• Research PaperVolume 6, Issue 12pp 1064-1075

  Pathway activation profiling reveals new insights into Age-related Macular Degeneration and provides avenues for therapeutic interventions

  Relevance score: 0.00

  Evgeny Makarev, Charles Cantor, Alex Zhavoronkov, Anton Buzdin, Alexander Aliper, Antonei Benjamin Csoka

  Keywords: AMD, Age-related Macular Degeneration, gene expression, Transcriptome profiling, signaling pathway activation strength

  Published in Aging on December 22, 2014

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• Research PaperVolume 4, Issue 1pp 49-59

  Quantitative trait loci on chromosome 1 for cataract and AMD-like retinopathy in senescence-accelerated OXYS rats

  Relevance score: 0.00

  Elena E. Korbolina, Ouyna S. Kozhevnikova, Nataliya A. Stefanova, Natalia G. Kolosova

  Keywords: age-related macular degeneration, cataract, senescence-accelerated OXYS rats, QTL analysis, congenic strains

  Published in Aging on January 31, 2012

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• Research PaperVolume 3, Issue 1pp 44-54

  Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS rats

  Relevance score: 0.00

  Anton M. Markovets, Valeriya B. Saprunova, Anna A. Zhdankina, Anzhella Zh. Fursova, Lora E. Bakeeva, Natalia G. Kolosova

  Keywords: age-related macular degeneration, OXYS rats, molecular mechanism of pathogenesis, vascular endothelial growth factor, pigment epithelium-derived factor

  Published in Aging on December 12, 2010

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• Research PaperVolume 2, Issue 12pp 981-989

  CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits

  Relevance score: 0.00

  Emilie Picard, Marianne Houssier, Kim Bujold, Przemyslaw Sapieha, William Lubell, Allison Dorfman, Julie Racine, Pierre Hardy, Maria Febbraio, Pierre Lachapelle, Huy Ong, Florian Sennlaub, Sylvain Chemtob

  Keywords: CD36, oxidized lipids, Bruch's membrane, age-related macular degeneration

  Published in Aging on November 9, 2010

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• Research PerspectiveVolume 1, Issue 8pp 740-745

  What determines the switch between atrophic and neovascular forms ofage related macular degeneration? - the role of BMP4 induced senescence

  Relevance score: 0.00

  DanHong Zhu, Xuemei Deng, Jing Xu, David R Hinton

  Keywords: BMP4, age related macular degeneration, senescence, retinal pigment epithelial cell, oxidative stress

  Published in Aging on August 12, 2009

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• Research PaperVolume 1, Issue 2pp 266-274

  Positive association of common variants in CD36 with neovascular age-related macular degeneration

  Relevance score: 0.00

  Naoshi Kondo, Shigeru Honda, Shin-ichi Kuno, Akira Negi

  Keywords: age-related macular degeneration, choroidal neovascularization, CD36, genetics, single nucleotide polymorphism, association

  Published in Aging on February 12, 2009

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• Research PaperVolume 13, Issue 19pp 23182-23192

  Decreased gray matter volume and increased white matter volume in patients with neovascular age-related macular degeneration: a voxel-based morphometry study

  Relevance score: 0.00

  Yan-Kun Shen, Qian-Min Ge, Yi-Cong Pan, Hui-Ye Shu, Li-Juan Zhang, Qiu-Yu Li, Rong-Bin Liang, Yi Shao, Yao Yu

  Keywords: neovascular age-related macular degeneration, choroidal neovascularization, mental disorder

  Published in Aging on October 6, 2021

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• Research PaperVolume 9, Issue 1pp 133-141

  Association of neovascular age-related macular degeneration with month and season of birth in Italy

  Relevance score: 0.00

  Antonio Longo, Alessandra Casuccio, Luca Pani, Teresio Avitabile, Salvatore Cillino, Maurizio G. Uva, Vincenza Bonfiglio, Andrea Russo, Guglielmo Parisi, Gilda Cennamo, Claudio Furino, Mariacristina Parravano, Entela Xoxi, Michele Reibaldi

  Keywords: neovascular age-related macular degeneration, neovascular AMD, anti-VEGF, season of birth, month of birth

  Published in Aging on December 19, 2016

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• Research PaperVolume 16, Issue 6pp 5435-5451

  Identification of key lncRNAs in age-related macular degeneration through integrated bioinformatics and experimental validation

  Relevance score: 0.00

  Yuying Ji, Chengguo Zuo, Nanying Liao, Liwei Yao, Ruijun Yang, Hui Chen, Feng Wen

  Keywords: noncoding RNA, age-related macular degeneration, bioinformatics, LINC00276, senescence

  Published in Aging on March 14, 2024

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