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Volume 3, Issue 1

January 2011pp 1—76

Commentaries

SIRT3: Striking at the heart of aging

Yufei Liu, Dan Zhang, Danica Chen

https://doi.org/10.18632/aging.100256pp 1—2

Be quiet and you'll keep young: does mTOR underlie p53 action in protecting against senescence by favoring quiescence?

Vjekoslav Dulic

https://doi.org/10.18632/aging.100257pp 3—4

The role of glyoxalases for sugar stress and aging, with relevance for dyskinesia, anxiety, dementia and Parkinson's disease

Georg Auburger, Alexander Kurz

https://doi.org/10.18632/aging.100258pp 5—9

Regulation of the mitochondrial transition pore: impact on mammalian aging

Heinz D. Osiewacz

https://doi.org/10.18632/aging.100259pp 10—11

Sirt3 targets mPTP and prevents aging in the heart

Junichi Sadoshima

https://doi.org/10.18632/aging.100266pp 12—13

Treating transgenic Alzheimer mice with a β-secretase inhibitor, what have we learned?

Jordan Tang, Arun Ghosh

https://doi.org/10.18632/aging.100267pp 14—16

The glyoxalase system as an example of a cellular maintenance pathway with relevance to aging

Axel Kowald

https://doi.org/10.18632/aging.100268pp 17—18

Manipulating ovarian aging: A new frontier in fertility preservation

Kutluk Oktay, Sumanta Goswami, Zbigniew Darzynkiewicz

https://doi.org/10.18632/aging.100269pp 19—21

Essay

Cellular proteome, coregulators, endocrine system and the human brain: the Regulatory biology of humanism

Bert W. O'Malley

https://doi.org/10.18632/aging.100270pp 22—25

Research Perspective

p53 governs telomere regulation feedback too, via TRF2

Izumi Horikawa, Kaori Fujita, Curtis C. Harris

https://doi.org/10.18632/aging.100271pp 26—32

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Research Papers

HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation

Lavinia Nardinocchi, Rosa Puca, Gabriella D'Orazi

https://doi.org/10.18632/aging.100254pp 33—43

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Alterations of retinal pigment epithelium cause AMD-like retinopathy in senescence-accelerated OXYS rats

Anton M. Markovets, Valeriya B. Saprunova, Anna A. Zhdankina, Anzhella Zh. Fursova, Lora E. Bakeeva, Natalia G. Kolosova

https://doi.org/10.18632/aging.100243pp 44—54

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Polymorphisms associated with type 2 diabetes in familial longevity: The Leiden Longevity Study

Simon P. Mooijaart, Diana van Heemst, Raymond Noordam, Maarten P. Rozing, Carolien A. Wijsman, Anton J.M. de Craen, Rudi G.J. Westendorp, Marian Beekman, Eline P. Slagboom

https://doi.org/10.18632/aging.100250pp 55—62

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Clinical Research Paper

Health and function of participants in the Long Life Family Study: A comparison with other cohorts

Anne B. Newman, Nancy W. Glynn, Christopher A. Taylor, Paola Sebastiani, Thomas T. Perls, Richard Mayeux, Kaare Christensen, Joseph M. Zmuda, Sandra Barral, Joseph H. Lee, Eleanor M. Simonsick, Jeremy D. Walston, Anatoli I. Yashin, Evan Hadley

https://doi.org/10.18632/aging.100242pp 63—76

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