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Volume 2, Issue 12

December 2010
pp 884—1029
Explore This Issue

BioEssay

Why the disposable soma theory cannot explain why women live longer and why we age

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100253 pp 884—887
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Commentaries

The role of CD36 receptor in the phagocytosis of oxidized lipids and AMD

Yves Courtois,
https://doi.org/10.18632/aging.100237 pp 888—889
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STAT3, HIF-1, glucose addiction and Warburg effect

James E. Darnell Jr,
https://doi.org/10.18632/aging.100239 pp 890—891
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mTOR and its link to the picture of Dorian Gray - re-activation of mTOR promotes aging

Józefa Węsierska-Gądek,
https://doi.org/10.18632/aging.100240 pp 892—893
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Perspectives on cellular senescence and short term dietary restriction in adults

James L. Kirkland,
https://doi.org/10.18632/aging.100247 pp 894—896
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Preview

Metformin and sex: why suppression of aging may be harmful to young male mice

Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100264 pp 897—899
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Review

The DNA damage response: Balancing the scale between cancer and ageing

Elena G. Seviour, Shiaw-Yih Lin,
https://doi.org/10.18632/aging.100248 pp 900—907
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Research Papers

The age of the target cell affects B-cell leukaemia malignancy

Carolina Vicente-Dueñas, Fernando Abollo-Jiménez, Lucía Ruiz-Roca, Esther Alonso-Escudero, Rafael Jiménez, María Begoña García Cenador, Francisco Javier García Criado, César Cobaleda, Isidro Sánchez-García,
https://doi.org/10.18632/aging.100244 pp 908—913
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Regulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy

Angela V. Hafner, Jing Dai, Ana P. Gomes, Chun-Yang Xiao, Carlos M. Palmeira, Anthony Rosenzweig, David A. Sinclair,
https://doi.org/10.18632/aging.100252 pp 914—923
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DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence

Olga V. Leontieva, Mikhail V. Blagosklonny,
https://doi.org/10.18632/aging.100265 pp 924—935
View Abstract PDF Full-Text How to Cite Special Collection on Cell Senescence and Rapamycin

Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice

Yuliya V. Dubrovsky, William E. Samsa, Roman V. Kondratov,
https://doi.org/10.18632/aging.100241 pp 936—944
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Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice

Vladimir N. Anisimov, Tatiana S. Piskunova, Irina G. Popovich, Mark A. Zabezhinski, Margarita L. Tyndyk, Peter A. Egormin, Maria N. Yurova, Svetlana V. Rosenfeld, Anna V. Semenchenko, Irina G. Kovalenko, Tatiana E. Poroshina, Lev M. Berstein,
https://doi.org/10.18632/aging.100245 pp 945—958
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Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells

Yiping Huang, Edward A. Ratovitski,
https://doi.org/10.18632/aging.100249 pp 959—968
View Abstract PDF Full-Text How to Cite Special Collection on Cancer and mTOR

Modulation of the glyoxalase system in the aging model Podospora anserina: effects on growth and lifespan

Christian Q. Scheckhuber, Sandra J. Mack, Ingmar Strobel, Filomena Ricciardi, Suzana Gispert, Heinz D. Osiewacz,
https://doi.org/10.18632/aging.100251 pp 969—980
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CD36 plays an important role in the clearance of oxLDL and associated age-dependent sub-retinal deposits

Emilie Picard, Marianne Houssier, Kim Bujold, Przemyslaw Sapieha, William Lubell, Allison Dorfman, Julie Racine, Pierre Hardy, Maria Febbraio, Pierre Lachapelle, Huy Ong, Florian Sennlaub, Sylvain Chemtob,
https://doi.org/10.18632/aging.100218 pp 981—989
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Statin prevents chondrocyte aging and degeneration of articular cartilage in osteoarthritis (OA)

Kazuo Yudoh, Rie Karasawa,
https://doi.org/10.18632/aging.100213 pp 990—998
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Systemic signals in aged males exert potent rejuvenating effects on the ovarian follicle reserve in mammalian females

Yuichi Niikura, Teruko Niikura, Ning Wang, Chonthicha Satirapod, Jonathan L. Tilly,
https://doi.org/10.18632/aging.100255 pp 999—1003
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Research Perspectives

Opposing function of mitochondrial prohibitin in aging

Marta Artal-Sanz, Nektarios Tavernarakis,
https://doi.org/10.18632/aging.100246 pp 1004—1011
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The NADPH Oxidase Nox4 and Aging in the Heart

Tetsuro Ago, Shouji Matsushima, Junya Kuroda, Daniela Zablocki, Takanari Kitazono, Junichi Sadoshima,
https://doi.org/10.18632/aging.100261 pp 1012—1016
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Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?

Alejandro P. Ugalde, Guillermo Mariño, Carlos López-Otín,
https://doi.org/10.18632/aging.100262 pp 1017—1022
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Zfra is a small wizard in the mitochondrial apoptosis

Subhan Dudekula, Ming-Hui Lee, Li-Jin Hsu, Shean-Jen Chen, Nan-Shan Chang,
https://doi.org/10.18632/aging.100263 pp 1023—1029
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