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The cover features Figure 1 "Expression of Dlx5 in adult brain" from de Lombarese et al.

Volume 11, Issue 17

15 September, 2019
pp 6614—7328

About the Cover

The cover features Figure 1 "Expression of Dlx5 in adult brain" from de Lombarese et al.


Explore This Issue

Editorials

TLR8 reprograms human Treg metabolism and function

Xia Liu, Lingyun Li, Guangyong Peng,
https://doi.org/10.18632/aging.102223 pp 6614—6615
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Neuronal microtubules impact lifespan

Ellen Apple, Lizhen Chen,
https://doi.org/10.18632/aging.102224 pp 6616—6617
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Aspirin for primary prevention in the elderly

Marwan Saad, Hesham K. Abdelaziz, Jawahar L. Mehta,
https://doi.org/10.18632/aging.102255 pp 6618—6619
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Is RAGE the receptor for inflammaging?

Marie Frimat, Thibault Teissier, Eric Boulanger,
https://doi.org/10.18632/aging.102256 pp 6620—6621
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Perfect energy stability in neurons

L. Felipe Barros, Felipe Baeza-Lehnert,
https://doi.org/10.18632/aging.102257 pp 6622—6623
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Neutrophils fertilize the pre-metastatic niche

WonJae Lee, Honami Naora,
https://doi.org/10.18632/aging.102258 pp 6624—6625
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Research Papers

Age-specific urinary metabolite signatures and functions in patients with major depressive disorder

Jian-Jun Chen, Jing Xie, Wen-Wen Li, Shun-Jie Bai, Wei Wang, Peng Zheng, Peng Xie,
https://doi.org/10.18632/aging.102133 pp 6626—6637
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Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan

Camille de Lombares, Eglantine Heude, Gladys Alfama, Anastasia Fontaine, Rim Hassouna, Cécile Vernochet, Fabrice de Chaumont, Christophe Olivo-Marin, Elodie Ey, Sébastien Parnaudeau, François Tronche, Thomas Bourgeron, Serge Luquet, Giovanni Levi, Nicolas Narboux-Nême,
https://doi.org/10.18632/aging.102141 pp 6638—6656
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LncRNA MIR4435-2HG targets desmoplakin and promotes growth and metastasis of gastric cancer by activating Wnt/β-catenin signaling

Haiyong Wang, Mengjie Wu, Yimin Lu, Kuifeng He, Xiaolu Cai, Xiongfei Yu, Jun Lu, Lisong Teng,
https://doi.org/10.18632/aging.102164 pp 6657—6673
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RPN2 promotes metastasis of hepatocellular carcinoma cell and inhibits autophagy via STAT3 and NF-κB pathways

Linsheng Huang, Zhiyuan Jian, Yi Gao, Ping Zhou, Gan Zhang, Bin Jiang, Yi Lv,
https://doi.org/10.18632/aging.102167 pp 6674—6690
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PU-91 drug rescues human age-related macular degeneration RPE cells; implications for AMD therapeutics

Sonali Nashine, Sudhakar R. Subramaniam, Marilyn Chwa, Anthony Nesburn, Baruch D. Kuppermann, Howard Federoff, M. Cristina Kenney,
https://doi.org/10.18632/aging.102179 pp 6691—6713
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MeCP2 inhibits cell functionality through FoxO3a and autophagy in endothelial progenitor cells

Siyuan Zha, Zhen Li, Shuyan Chen, Fang Liu, Fei Wang,
https://doi.org/10.18632/aging.102183 pp 6714—6733
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MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer

Chunhua Wei, Ruiguang Zhang, Qian Cai, Xican Gao, Fan Tong, Jihua Dong, Yu Hu, Gang Wu, Xiaorong Dong,
https://doi.org/10.18632/aging.102201 pp 6734—6761
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Knockout of p75 neurotrophin receptor attenuates the hyperphosphorylation of Tau in pR5 mouse model

Noralyn B. Mañucat-Tan, Lin-Lin Shen, Larisa Bobrovskaya, Mohammed Al-hawwas, Fiona H. Zhou, Yan-Jiang Wang, Xin-Fu Zhou,
https://doi.org/10.18632/aging.102202 pp 6762—6791
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Stress adaptation in older adults with and without cognitive impairment: an fMRI pattern-based similarity analysis

Xixi Wang, Kathi L. Heffner, Mia Anthony, Feng Lin,
https://doi.org/10.18632/aging.102204 pp 6792—6804
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Long non-coding RNA, HOTAIRM1, promotes glioma malignancy by forming a ceRNA network

Qingyu Liang, Xue Li, Gefei Guan, Xiaoyan Xu, Chen Chen, Peng Cheng, Wen Cheng, Anhua Wu,
https://doi.org/10.18632/aging.102205 pp 6805—6838
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Prognostic value of subclinical thyroid dysfunction in ischemic stroke patients treated with intravenous thrombolysis

Xiaohao Zhang, Pengyu Gong, Lei Sheng, Yanni Lin, Qiqi Fan, Yun Zhang, Yuanfei Bao, Shizhan Li, Hongcai Du, Zhonglun Chen, Caixia Ding, Huaiming Wang, Pengfei Xu, Min Zhang, Fabien Scalzo, David S. Liebeskind, Yi Xie, Dezhi Liu,
https://doi.org/10.18632/aging.102215 pp 6839—6850
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Apolipoprotein B/AI ratio as an independent risk factor for intracranial atherosclerotic stenosis

Yan Sun, Xiao-He Hou, Dong-Dong Wang, Ya-Hui Ma, Chen-Chen Tan, Fu-Rong Sun, Mei Cui, Qiang Dong, Lan Tan, Jin-Tai Yu,
https://doi.org/10.18632/aging.102216 pp 6851—6862
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Risk of sepsis among patients with COPD treated with fixed combinations of inhaled corticosteroids and long-acting Beta2 agonists

Cheng-Yi Wang, You Shuei Lin, Ya-Hui Wang, Chih-Cheng Lai, Hao-Chien Wang, Likwang Chen, Chong-Jen Yu,
https://doi.org/10.18632/aging.102217 pp 6863—6871
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Cholesterol lowering attenuates pressure overload-induced heart failure in mice with mild hypercholesterolemia

Ilayaraja Muthuramu, Mudit Mishra, Joseph Pierre Aboumsallem, Andrey Postnov, Olivier Gheysens, Bart De Geest,
https://doi.org/10.18632/aging.102218 pp 6872—6891
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Construction of a comprehensive observer-based scale assessing aging-related health and functioning in captive rhesus macaques

Wei Deng, Guoying Guan, Chong Xiao, Guangjin Qu, Jing Xue, Chuan Qin, Hui Han, Yuhong Wang,
https://doi.org/10.18632/aging.102219 pp 6892—6903
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Neurofilament light chain plasma concentration predicts neurodegeneration and clinical progression in nondemented elderly adults

Hao Hu, Ke-Liang Chen, Ya-Nan Ou, Xi-Peng Cao, Shi-Dong Chen, Mei Cui, Qiang Dong, Lan Tan, Jin-Tai Yu, Alzheimer’s Disease Neuroimaging Initiative,
https://doi.org/10.18632/aging.102220 pp 6904—6914
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Antibiotic-induced microbiome depletion protects against MPTP-induced dopaminergic neurotoxicity in the brain

Yaoyu Pu, Lijia Chang, Youge Qu, Siming Wang, Kai Zhang, Kenji Hashimoto,
https://doi.org/10.18632/aging.102221 pp 6915—6929
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An eight-long non-coding RNA signature as a candidate prognostic biomarker for bladder cancer

Penghu Lian, Qian Wang, Ya Zhao, Cheng Chen, Xiacheng Sun, Hanzhong Li, Jianhua Deng, Hongmei Zhang, Zhigang Ji, Xuebin Zhang, Qichao Huang,
https://doi.org/10.18632/aging.102225 pp 6930—6940
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Erythropoietin prevents dementia in hemodialysis patients: a nationwide population-based study

Peir-Haur Hung, Chih-Ching Yeh, Fung-Chang Sung, Chih-Yen Hsiao, Chih-Hsin Muo, Kuan-Yu Hung, Kuen-Jer Tsai,
https://doi.org/10.18632/aging.102227 pp 6941—6950
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Kindlin-3 in platelets and myeloid cells differentially regulates deep vein thrombosis in mice

Yanyan Yan, Hongqin Yang, Xiao Hu, Zeping Zhang, Shushu Ge, Zhen Xu, Juan Gao, Junling Liu, Gilbert C. White, Yan-Qing Ma,
https://doi.org/10.18632/aging.102229 pp 6951—6959
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TPM2 as a potential predictive biomarker for atherosclerosis

Ling-Bing Meng, Meng-Jie Shan, Yong Qiu, Ruomei Qi, Ze-Mou Yu, Peng Guo, Chen-Yi Di, Tao Gong,
https://doi.org/10.18632/aging.102231 pp 6960—6982
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Curcumin suppresses osteogenesis by inducing miR-126a-3p and subsequently suppressing the WNT/LRP6 pathway

Hongling Li, Lifeng Yue, Haoying Xu, Na Li, Jing Li, Zhiguo Zhang, Robert Chunhua Zhao,
https://doi.org/10.18632/aging.102232 pp 6983—6998
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Prognostic value and immune infiltration of novel signatures in clear cell renal cell carcinoma microenvironment

Wen-Hao Xu, Yue Xu, Jun Wang, Fang-Ning Wan, Hong-Kai Wang, Da-Long Cao, Guo-Hai Shi, Yuan-Yuan Qu, Hai-Liang Zhang, Ding-Wei Ye,
https://doi.org/10.18632/aging.102233 pp 6999—7020
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Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging

Ruiyun Wang, Lihua Liu, Hongxia Liu, Kefei Wu, Yun Liu, Lijuan Bai, Qian Wang, Benming Qi, Benling Qi, Lei Zhang,
https://doi.org/10.18632/aging.102234 pp 7021—7035
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Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells

Jie Liang, Fanlin Zhou, Xiaomin Xiong, Xiong Zhang, Shijie Li, Xiaoju Li, Minna Gao, Yu Li,
https://doi.org/10.18632/aging.102235 pp 7036—7050
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Effects of age-dependent changes in cell size on endothelial cell proliferation and senescence through YAP1

Tadanori Mammoto, Yu-Suke Torisawa, Megan Muyleart, Kathryn Hendee, Charles Anugwom, David Gutterman, Akiko Mammoto,
https://doi.org/10.18632/aging.102236 pp 7051—7069
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Chondrocyte sheet in vivo cartilage regeneration technique using miR-193b-3p to target MMP16

Xia Chen, Ruhong Zhang, Qun Zhang, Zhicheng Xu, Feng Xu, Datao Li, Yiyuan Li,
https://doi.org/10.18632/aging.102237 pp 7070—7082
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Telomere length, vitamin B12 and mortality in persons undergoing coronary angiography: the Ludwigshafen risk and cardiovascular health study

Irene Pusceddu, Wolfgang Herrmann, Marcus E. Kleber, Hubert Scharnagl, Winfried März, Markus Herrmann,
https://doi.org/10.18632/aging.102238 pp 7083—7097
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lncRNA miat functions as a ceRNA to upregulate sirt1 by sponging miR-22-3p in HCC cellular senescence

Lijun Zhao, Kexin Hu, Jianzhong Cao, Pan Wang, Jun Li, Kewu Zeng, Xiaodong He, Peng-Fei Tu, Tanjun Tong, Limin Han,
https://doi.org/10.18632/aging.102240 pp 7098—7122
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Chromobox homolog 8 (CBX8) Interacts with Y-Box binding protein 1 (YBX1) to promote cellular proliferation in hepatocellular carcinoma cells

Lushan Xiao, Zixiao Zhou, Wenwen Li, Jie Peng, Qingcan Sun, Hongbo Zhu, Yang Song, Jin-Lin Hou, Jingyuan Sun, Hui-Chuan Cao, Dong Zhongyi, Dehua Wu, Li Liu,
https://doi.org/10.18632/aging.102241 pp 7123—7149
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Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan

Julia Adelöf, Jaime M. Ross, Stanley E. Lazic, Madeleine Zetterberg, John Wiseman, Malin Hernebring,
https://doi.org/10.18632/aging.102242 pp 7150—7168
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Cognitive efficiency in late midlife is linked to lifestyle characteristics and allostatic load

Justinas Narbutas, Maxime Van Egroo, Daphne Chylinski, Pamela Villar González, Claudia Garcia Jimenez, Gabriel Besson, Pouya Ghaemmaghami, Grégory Hammad, Vincenzo Muto, Christina Schmidt, André Luxen, Eric Salmon, Pierre Maquet, Christine Bastin, Gilles Vandewalle, Fabienne Collette,
https://doi.org/10.18632/aging.102243 pp 7169—7186
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STAT3 inhibitor sensitized KRAS-mutant lung cancers to RAF inhibitor by activating MEK/ERK signaling pathway

Zhenlin Wang, Mengchen Yin, Peilin Chu, Meiqing Lou,
https://doi.org/10.18632/aging.102244 pp 7187—7196
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A cohort study of antihyperglycemic medication exposure and survival in patients with gastric cancer

Audrius Dulskas, Ausvydas Patasius, Donata Linkeviciute-Ulinskiene, Lina Zabuliene, Giedre Smailyte,
https://doi.org/10.18632/aging.102245 pp 7197—7205
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Dynamic PML protein nucleolar associations with persistent DNA damage lesions in response to nucleolar stress and senescence-inducing stimuli

Terezie Imrichova, Sona Hubackova, Alena Kucerova, Jan Kosla, Jiri Bartek, Zdenek Hodny, Pavla Vasicova,
https://doi.org/10.18632/aging.102248 pp 7206—7235
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Mouse mammary tumor virus (MMTV) - like exogenous sequences are associated with sporadic but not hereditary human breast carcinoma

Antonio Giuseppe Naccarato, Francesca Lessi, Katia Zavaglia, Cristian Scatena, Mohammad A. Al Hamad, Paolo Aretini, Michele Menicagli, Manuela Roncella, Matteo Ghilli, Maria Adelaide Caligo, Chiara Maria Mazzanti, Generoso Bevilacqua,
https://doi.org/10.18632/aging.102252 pp 7236—7241
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Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions

Unbin Chae, Jeen-Woo Park, Sang-Rae Lee, Hong Jun Lee, Hyun-Shik Lee, Dong-Seok Lee,
https://doi.org/10.18632/aging.102259 pp 7242—7256
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Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer’s disease

Chao Zhou, Xiaoyu Sun, Yuting Hu, Jiaxing Song, Shuyu Dong, Delian Kong, Yuqiao Wang, Xiaodong Hua, Jingjing Han, Yan Zhou, Guoliang Jin, Xinxin Yang, Hongjuan Shi, Zuohui Zhang, Fang Hua,
https://doi.org/10.18632/aging.102260 pp 7257—7273
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The activation of cardiac dSir2-related pathways mediates physical exercise resistance to heart aging in old Drosophila

Deng-Tai Wen, Lan Zheng, Jin-Xiu Li, Kai Lu, Wen-Qi Hou,
https://doi.org/10.18632/aging.102261 pp 7274—7293
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Impact of NF-κB pathway on the apoptosis-inflammation-autophagy crosstalk in human degenerative nucleus pulposus cells

Weiwei Yi, Yafeng Wen, Fuqiang Tan, Xi Liu, Haiyang Lan, He Ye, Bo Liu,
https://doi.org/10.18632/aging.102266 pp 7294—7306
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Review

Metabolic remodeling induced by mitokines in heart failure

Jiahao Duan, Zijun Chen, Yeshun Wu, Bin Zhu, Ling Yang, Chun Yang,
https://doi.org/10.18632/aging.102247 pp 7307—7327
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Correction

Correction for: The combination of lonafarnib and sorafenib induces cyclin D1 degradation via ATG3-mediated autophagic flux in hepatocellular carcinoma cells

Jialiang Wang, Huan Wei, Yanlin Huang, Dongmei Chen, Guofen Zeng, Yifan Lian, Yuehua Huang,
https://doi.org/10.18632/aging.102289 pp 7328
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