Online ISSN: 1945-4589
The cover features Figure 1 "Protective effects of NMN administration in the early phase of retinal detachment (RD)“ from Chen et al.

Volume 12, Issue 24

31 December, 2020
pp 24476—26279

About the Cover

The cover features Figure 1 "Protective effects of NMN administration in the early phase of retinal detachment (RD)“ from Chen et al.


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Editorials

Arterial elementary calcium signaling in aging

Mario Kassmann, Gang Fan, Maik Gollasch,
https://doi.org/10.18632/aging.104220 pp 24476—24478
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Sugar-induced dysregulation of purine metabolism impacts lifespan

Claudia Lennicke, Eliano dos Santos, Helena M. Cochemé,
https://doi.org/10.18632/aging.104223 pp 24479—24480
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Research Perspective

The Ercc1-/Δ mouse model of accelerated senescence and aging for identification and testing of novel senotherapeutic interventions

Alec Wong, Tra Kieu, Paul D. Robbins,
https://doi.org/10.18632/aging.202321 pp 24481—24483
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Meeting Report

ARDD 2020: from aging mechanisms to interventions

Garik V. Mkrtchyan, Kotb Abdelmohsen, Pénélope Andreux, Ieva Bagdonaite, Nir Barzilai, Søren Brunak, Filipe Cabreiro, Rafael de Cabo, Judith Campisi, Ana Maria Cuervo, Marco Demaria, Collin Y. Ewald, Evandro Fei Fang, Richard Faragher, Luigi Ferrucci, Adam Freund, Carlos G. Silva-García, Anastasia Georgievskaya, Vadim N. Gladyshev, David J. Glass, Vera Gorbunova, Aubrey de Grey, Wei-Wu He, Jan Hoeijmakers, Eva Hoffmann, Steve Horvath, Riekelt H. Houtkooper, Majken K. Jensen, Martin Borch Jensen, Alice Kane, Moustapha Kassem, Peter de Keizer, Brian Kennedy, Gerard Karsenty, Dudley W. Lamming, Kai-Fu Lee, Nanna MacAulay, Polina Mamoshina, Jim Mellon, Marte Molenaars, Alexey Moskalev, Andreas Mund, Laura Niedernhofer, Brenna Osborne, Heidi H. Pak, Andrey Parkhitko, Nuno Raimundo, Thomas A. Rando, Lene Juel Rasmussen, Carolina Reis, Christian G. Riedel, Anais Franco-Romero, Björn Schumacher, David A. Sinclair, Yousin Suh, Pam R. Taub, Debra Toiber, Jonas T. Treebak, Dario Riccardo Valenzano, Eric Verdin, Jan Vijg, Sergey Young, Lei Zhang, Daniela Bakula, Alex Zhavoronkov, Morten Scheibye-Knudsen,
https://doi.org/10.18632/aging.202454 pp 24484—24503
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Priority Research Paper

Neuroprotective effects and mechanisms of action of nicotinamide mononucleotide (NMN) in a photoreceptor degenerative model of retinal detachment

Xiaohong Chen, João A. Amorim, Giannis A. Moustafa, Jong-Jer Lee, Zhen Yu, Kenji Ishihara, Yasuhiro Iesato, Paulo Barbisan, Takashi Ueta, Konstantina A. Togka, Lin Lu, David A. Sinclair, Demetrios G. Vavvas,
https://doi.org/10.18632/aging.202453 pp 24504—24521
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Research Papers

COVID-19
Mortality in an Italian nursing home during COVID-19 pandemic: correlation with gender, age, ADL, vitamin D supplementation, and limitations of the diagnostic tests

Biagio Cangiano, Letizia Maria Fatti, Leila Danesi, Giacomo Gazzano, Marina Croci, Giovanni Vitale, Luisa Gilardini, Stefania Bonadonna, Iacopo Chiodini, Chiara Francesca Caparello, Antonio Conti, Luca Persani, Marco Stramba-Badiale, Marco Bonomi,
https://doi.org/10.18632/aging.202307 pp 24522—24534
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COVID-19
Coagulopathy in patients with COVID-19: a systematic review and meta-analysis

Xiaolin Zhang, Xue Yang, Hongmei Jiao, Xinmin Liu,
https://doi.org/10.18632/aging.104138 pp 24535—24551
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COVID-19
Clinical outcomes of patients hospitalized for COVID-19 versus SARS: a meta-analysis

Po-Cheng Chang, Chien-Chang Yang, Kuo-Chin Kao, Ming-Shien Wen,
https://doi.org/10.18632/aging.104139 pp 24552—24569
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COVID-19
Association between ageing population, median age, life expectancy and mortality in coronavirus disease (COVID-19)

Xue-Qiang Wang, Ge Song, Zheng Yang, Ren-Jie Chen, Yi-Li Zheng, Hao-Yu Hu, Xuan Su, Pei-Jie Chen,
https://doi.org/10.18632/aging.104193 pp 24570—24578
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COVID-19
Characteristics of mortal COVID-19 cases compared to the survivors

Xianghui Zhou, Zhipeng Cheng, Dan Shu, Wenyi Lin, Zhangyin Ming, Wei Chen, Yu Hu,
https://doi.org/10.18632/aging.202216 pp 24579—24595
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COVID-19
Dynamic monitoring of immune function indexes in COVID-19 patients

Yaohui Song, Huixiu Zhong, Lin Li, Minggang Yin, Yi Yin, Xiaolong Guo, Bo Zhang, Weiping Liu,
https://doi.org/10.18632/aging.202362 pp 24596—24603
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Control of lifespan and survival by Drosophila NF-κB signaling through neuroendocrine cells and neuroblasts

Sinan Khor, Dongsheng Cai,
https://doi.org/10.18632/aging.104196 pp 24604—24622
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The reliability, validity, and sensitivity of the Edmonton Frail Scale (EFS) in older adults with foot disorders

Emmanuel Navarro-Flores, Ricardo Becerro de Bengoa Vallejo, Marta Elena Losa-Iglesias, Patricia Palomo-López, César Calvo-Lobo, Daniel López-López, Eva Maria Martínez-Jiménez, Carlos Romero-Morales,
https://doi.org/10.18632/aging.202140 pp 24623—24632
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The impact of physical frailty on the response to inactivated influenza vaccine in older adults

Krissy K. Moehling, Bo Zhai, William E. Schwarzmann, Uma R. Chandran, Marianna Ortiz, Mary Patricia Nowalk, David Nace, Chyongchiou J. Lin, Michael Susick, Min Z. Levine, John F. Alcorn, Richard K. Zimmerman,
https://doi.org/10.18632/aging.202207 pp 24633—24650
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Downregulated genes by silencing MYC pathway identified with RNA-SEQ analysis as potential prognostic biomarkers in gastric adenocarcinoma

Jersey Heitor da Silva Maués, Helem Ferreira Ribeiro, Raquel de Maria Maués Sacramento, Rafael Maia de Sousa, Raíssa Pereira de Tommaso, Bruno Dourado Kovacs Machado Costa, Paulo Cardoso Soares, Paulo Pimentel Assumpção, Caroline de Fátima Aquino Moreira-Nunes, Rommel Mário Rodriguez Burbano,
https://doi.org/10.18632/aging.202260 pp 24651—24670
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Progesterone receptor isoform-dependent cross-talk between prolactin and fatty acid synthase in breast cancer

Javier A. Menendez, Susan K. Peirce, Adriana Papadimitropoulou, Elisabet Cuyàs, Travis Vander Steen, Sara Verdura, Luciano Vellon, Wen Y. Chen, Ruth Lupu,
https://doi.org/10.18632/aging.202289 pp 24671—24692
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Beyond the social gradient: the role of lifelong socioeconomic status in older adults’ health trajectories

Lisa Harber-Aschan, Amaia Calderón-Larrañaga, Alexander Darin-Mattson, Xiaonan Hu, Laura Fratiglioni, Serhiy Dekhtyar,
https://doi.org/10.18632/aging.202342 pp 24693—24708
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Post-transplant colitis after kidney transplantation: clinical, endoscopic and histological features

Rossella Gioco, Lidia Puzzo, Marco Patanè, Daniela Corona, Giuseppe Trama, Pierfrancesco Veroux, Massimiliano Veroux,
https://doi.org/10.18632/aging.202345 pp 24709—24720
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Age and gender related differences in load-strain response in C57Bl/6 mice

Hammad Mumtaz, Nuria Lara-Castillo, JoAnna M. Scott, Mark Begonia, Mark Dallas, Mark L. Johnson, Thiagarajan Ganesh,
https://doi.org/10.18632/aging.202350 pp 24721—24733
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Biological characteristics of aging in human acute myeloid leukemia cells: the possible importance of aldehyde dehydrogenase, the cytoskeleton and altered transcriptional regulation

Maria Hernandez-Valladares, Elise Aasebø, Frode Berven, Frode Selheim, Øystein Bruserud,
https://doi.org/10.18632/aging.202361 pp 24734—24777
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L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis

Yassine Ouhaddi, Mehdi Najar, Frédéric Paré, Bertrand Lussier, Yoshihiro Urade, Mohamed Benderdour, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Hassan Fahmi,
https://doi.org/10.18632/aging.202367 pp 24778—24797
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Effects of choral singing versus health education on cognitive decline and aging: a randomized controlled trial

Lei Feng, Rafael Romero-Garcia, John Suckling, Jasmine Tan, Anis Larbi, Irwin Cheah, Glenn Wong, Maurine Tsakok, Bernard Lanskey, Darius Lim, Jialiang Li, Joanna Yang, Benjamin Goh, Tristan Gwee Chen Teck, Allan Ho, Xiu Wang, Jin-Tai Yu, Can Zhang, Crystal Tan, Michelle Chua, Junhua Li, John J Totman, Caroline Wong, Marie Loh, Roger Foo, Chay Hoon Tan, Lee Gan Goh, Rathi Mahendran, Brian K. Kennedy, Ee-Heok Kua,
https://doi.org/10.18632/aging.202374 pp 24798—24816
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A DNA methylation age predictor for zebrafish

Benjamin Mayne, Darren Korbie, Lisa Kenchington, Ben Ezzy, Oliver Berry, Simon Jarman,
https://doi.org/10.18632/aging.202400 pp 24817—24835
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miR-106b suppresses pathological retinal angiogenesis

Catherine Ménard, Ariel M. Wilson, Agnieszka Dejda, Khalil Miloudi, François Binet, Sergio Crespo-Garcia, Célia Parinot, Frédérique Pilon, Rachel Juneau, Elisabeth MMA Andriessen, Gaëlle Mawambo, John Paul SanGiovanni, Vincent De Guire, Przemyslaw Sapieha,
https://doi.org/10.18632/aging.202404 pp 24836—24852
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Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice

Xiaodong Mu, Chi-Yi Lin, William S. Hambright, Ying Tang, Sudheer Ravuri, Aiping Lu, Polina Matre, Wanqun Chen, Xueqin Gao, Yan Cui, Ling Zhong, Bing Wang, Johnny Huard,
https://doi.org/10.18632/aging.202413 pp 24853—24871
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Age-associated deficient recruitment of 53BP1 in G1 cells directs DNA double-strand break repair to BRCA1/CtIP-mediated DNA-end resection

Teresa Anglada, Anna Genescà, Marta Martín,
https://doi.org/10.18632/aging.202419 pp 24872—24893
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Obesity induced by high-fat diet is associated with critical changes in biological and molecular functions of mesenchymal stromal cells present in visceral adipose tissue

Mustafa Burak Acar, Şerife Ayaz-Güner, Giovanni Di Bernardo, Hüseyin Güner, Ayşegül Murat, Gianfranco Peluso, Servet Özcan, Umberto Galderisi,
https://doi.org/10.18632/aging.202423 pp 24894—24913
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Age-related transcriptome changes in melanoma patients with tumor-positive sentinel lymph nodes

Derek S. Menefee, Austin McMasters, Jianmin Pan, Xiaohong Li, Deyi Xiao, Sabine Waigel, Wolfgang Zacharias, Shesh N. Rai, Kelly M. McMasters, Hongying Hao,
https://doi.org/10.18632/aging.202435 pp 24914—24939
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Time gap between the onset and diagnosis in Werner syndrome: a nationwide survey and the 2020 registry in Japan

Masaya Koshizaka, Yoshiro Maezawa, Yukari Maeda, Mayumi Shoji, Hisaya Kato, Hiyori Kaneko, Takahiro Ishikawa, Daisuke Kinoshita, Kazuki Kobayashi, Junji Kawashima, Akiko Sekiguchi, Sei-ichiro Motegi, Hironori Nakagami, Yoshihiko Yamada, Shinji Tsukamoto, Akira Taniguchi, Ken Sugimoto, Yukiko Shoda, Kunihiko Hashimoto, Toru Yoshimura, Daisuke Suzuki, Masafumi Kuzuya, Minoru Takemoto, Koutaro Yokote,
https://doi.org/10.18632/aging.202441 pp 24940—24956
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LINC01410 accelerated the invasion and proliferation of osteosarcoma by sponging miR-3128

Quanxiao Xu, Limin He, Lei Ma, Lin Fan, Lihua Yan, Xulin Zhao, Yuanyuan Li,
https://doi.org/10.18632/aging.103464 pp 24957—24966
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HBXIP promotes gastric cancer via METTL3-mediated MYC mRNA m6A modification

Zhi Yang, Xiaodi Jiang, Deming Li, Xiaofeng Jiang,
https://doi.org/10.18632/aging.103767 pp 24967—24982
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A glycolysis-related gene expression signature in predicting recurrence of breast cancer

Jianing Tang, Yongwen Luo, Gaosong Wu,
https://doi.org/10.18632/aging.103806 pp 24983—24994
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DZIP3 is a key factor to stratify IDH1 wild-type lower-grade gliomas

Tingyu Liang, Xingang Zhou, Peiliang Li, Gan You, Fang Wang, Peng Wang, Enshan Feng,
https://doi.org/10.18632/aging.103817 pp 24995—25004
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Sleep quality and risk of coronary heart disease - a prospective cohort study from the English longitudinal study of ageing

Chenxi Song, Rui Zhang, Jiaqiang Liao, Rui Fu, Chunyue Wang, Qianqian Liu, Weihua Song, Hongjian Wang, Kefei Dou,
https://doi.org/10.18632/aging.103866 pp 25005—25019
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TRIB3 facilitates glioblastoma progression via restraining autophagy

Zhanbin Tang, Hongping Chen, Di Zhong, Wan Wei, Lili Liu, Qiong Duan, Baichao Han, Guozhong Li,
https://doi.org/10.18632/aging.103969 pp 25020—25034
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δ-opioid receptor activation protects against Parkinson’s disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy

Yuan Xu, Feng Zhi, Jiahao Mao, Ya Peng, Naiyuan Shao, Gianfranco Balboni, Yilin Yang, Ying Xia,
https://doi.org/10.18632/aging.103970 pp 25035—25059
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LINC01235-TWIST2 feedback loop facilitates epithelial–mesenchymal transition in gastric cancer by inhibiting THBS2

Yu-En Tan, Yao Xing, Ban-Lai Ran, Chao Zhang, Si-Wei Pan, Wen An, Qing-Chuan Chen, Hui-Mian Xu,
https://doi.org/10.18632/aging.103979 pp 25060—25075
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Secondary data mining of GEO database for long non-coding RNA and Competing endogenous RNA network in keloid-prone individuals

Yu Deng, Yangbin Xu, Shuqia Xu, Yujing Zhang, Bing Han, Zheng Liu, Xiangxia Liu, Zhaowei Zhu,
https://doi.org/10.18632/aging.104054 pp 25076—25089
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miR-100-3p inhibits the adipogenic differentiation of hMSCs by targeting PIK3R1 via the PI3K/AKT signaling pathway

Tao Wang, Donghuo Zhong, Zhongjun Qin, Shan He, Ying Gong, Weidong Li, Xingnuan Li,
https://doi.org/10.18632/aging.104074 pp 25090—25100
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Could microtubule inhibitors be the best choice of therapy in gastric cancer with high immune activity: mutant DYNC1H1 as a biomarker

Jin Bai, BoWen Yang, Ruichuan Shi, Xinye Shao, Yujing Yang, Fang Wang, Jiawen Xiao, Xiujuan Qu, Yunpeng Liu, Ye Zhang, Zhi Li,
https://doi.org/10.18632/aging.104084 pp 25101—25119
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Apelin protects against ischemia-reperfusion injury in diabetic myocardium via inhibiting apoptosis and oxidative stress through PI3K and p38-MAPK signaling pathways

Songtao An, Xi Wang, Huairui, Shi, Xueqiang Zhang, Hua Meng, Wenbo Li, Dongchang Chen, Junbo Ge,
https://doi.org/10.18632/aging.104106 pp 25120—25137
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Bone marrow mesenchymal stem cell-derived exosomes prevent osteoarthritis by regulating synovial macrophage polarization

Jiyong Zhang, Yuluo Rong, Chunyang Luo, Weiding Cui,
https://doi.org/10.18632/aging.104110 pp 25138—25152
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Integrated analysis of a competing endogenous RNA network reveals an 11-lncRNA prognostic signature in ovarian cancer

Yongjian Zhang, Hu Zhou, Meiyin Zhang, Linan Xing, Chang Yang, Bairong Xia, Ge Lou,
https://doi.org/10.18632/aging.104116 pp 25153—25171
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Vascular endothelial growth factor receptor-2 and its association with tumor immune regulatory gene expression in hepatocellular carcinoma

Ze-Long Liu, Ling-Ling Zhu, Jing-Hua Liu, Zhang-Ya Pu, Zhi-Ping Ruan, Jiang Chen,
https://doi.org/10.18632/aging.104119 pp 25172—25188
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Histone methyltransferase SETD2 inhibits tumor growth via suppressing CXCL1-mediated activation of cell cycle in lung adenocarcinoma

You Zhou, Xiao Zheng, Bin Xu, Haifeng Deng, Lujun Chen, Jingting Jiang,
https://doi.org/10.18632/aging.104120 pp 25189—25206
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Impairment of Pol β-related DNA base-excision repair leads to ovarian aging in mice

Ke Hua, Liping Wang, Junhua Sun, Nanhai Zhou, Yilan Zhang, Feng Ji, Li Jing, Yang Yang, Wen Xia, Zhigang Hu, Feiyan Pan, Xi Chen, Bing Yao, Zhigang Guo,
https://doi.org/10.18632/aging.104123 pp 25207—25228
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Exposure to ozone impacted Th1/Th2 imbalance of CD4+ T cells and apoptosis of ASMCs underlying asthmatic progression by activating lncRNA PVT1-miR-15a-5p/miR-29c-3p signaling

Yangyang Wei, Baofen Han, Wenjuan Dai, Shufang Guo, Caiping Zhang, Lixuan Zhao, Yan Gao, Yi Jiang, Xiaomei Kong,
https://doi.org/10.18632/aging.104124 pp 25229—25255
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A systematic review and network meta-analysis of single nucleotide polymorphisms associated with pancreatic cancer risk

Zhuo-Miao Ye, Li-Juan Li, Ming-Bo Luo, Hong-Yuan Qing, Jing-Hui Zheng, Chi Zhang, Yun-Xin Lu, You-Ming Tang,
https://doi.org/10.18632/aging.104128 pp 25256—25274
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DNA methylation-based lung adenocarcinoma subtypes can predict prognosis, recurrence, and immunotherapeutic implications

Feng Xu, Lulu He, Xueqin Zhan, Jiexin Chen, Huan Xu, Xiaoling Huang, Yangyi Li, Xiaohe Zheng, Ling Lin, Yongsong Chen,
https://doi.org/10.18632/aging.104129 pp 25275—25293
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Multiwalled carbon nanotubes inhibit cell migration and invasion by destroying actin cytoskeleton via mitochondrial dysfunction in ovarian cancer cells

Ping Zhang, Jiangyan Teng, Lijuan Wang,
https://doi.org/10.18632/aging.104130 pp 25294—25303
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Identification of novel prognostic biomarkers in renal cell carcinoma

Yuanzhang Zou, Qiu Lu, Qin Yao, Di Dong, Binghai Chen,
https://doi.org/10.18632/aging.104131 pp 25304—25318
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Cerebellar-limbic neurocircuit is the novel biosignature of physio-cognitive decline syndrome

Li-Kuo Liu, Kun-Hsien Chou, Chih-Chin Heather Hsu, Li-Ning Peng, Wei-Ju Lee, Wei-Ta Chen, Ching-Po Lin, Chih-Ping Chung, Pei-Ning Wang, Liang-Kung Chen,
https://doi.org/10.18632/aging.104135 pp 25319—25336
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Single cell sequencing reveals cell populations that predict primary resistance to imatinib in chronic myeloid leukemia

Weilong Zhang, Beibei Yang, Linqian Weng, Jiangtao Li, Jiefei Bai, Ting Wang, Jingwen Wang, Jin Ye, Hongmei Jing, Yuchen Jiao, Xixi Chen, Hui Liu, Yi-Xin Zeng,
https://doi.org/10.18632/aging.104136 pp 25337—25355
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Development and validation of a prognostic model for kidney renal clear cell carcinoma based on RNA binding protein expression

Yuzhu Xiang, Shengcai Zhou, Jian Hao, Chunhong Zhong, Qimei Ma, Zhuolun Sun, Chunxiao Wei,
https://doi.org/10.18632/aging.104137 pp 25356—25372
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Effect of paternal age on offspring birth defects: a systematic review and meta-analysis

Yiwei Fang, Yongfeng Wang, Meilin Peng, Jia Xu, Zunpan Fan, Chunyan Liu, Kai Zhao, Huiping Zhang,
https://doi.org/10.18632/aging.104141 pp 25373—25394
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Steroid 5 alpha-reductase 3 (SRD5A3) promotes tumor growth and predicts poor survival of human hepatocellular carcinoma (HCC)

Qicong Mai, Dafeng Sheng, Chengcong Chen, Qing Gou, Meng Chen, Xiaoting Huang, Heng Yin, Xiaoming Chen, Zide Chen,
https://doi.org/10.18632/aging.104142 pp 25395—25411
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DNA methylomic homogeneity and heterogeneity in muscles and testes throughout pig adulthood

Min Zheng, Shijun Xiao, Tianfu Guo, Lin Rao, Longyun Li, Zhiyan Zhang, Lusheng Huang,
https://doi.org/10.18632/aging.104143 pp 25412—25431
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Different doses of ovalbumin exposure on dendritic cells determine their genetic/epigenetic regulation and T cell differentiation

Ying Wang, Zizhong Yu, Yue Zhou, Yun Zhu, Jinhui Wang, Junmei Fu, Yang Yuan, Shan Chen, Yanjun Wang, Wenting Yu, Pei Gao, Wanting Zhu, Qing Cheng, Seong H Cho, Weijia Kong, Jianjun Chen,
https://doi.org/10.18632/aging.104145 pp 25432—25451
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Sevoflurane postconditioning reduces myocardial ischemia reperfusion injury-induced necroptosis by up-regulation of OGT-mediated O-GlcNAcylated RIPK3

Jing Zhang, Peng Yu, Fuzhou Hua, Yanhui Hu, Fan Xiao, Qin Liu, Dan Huang, Fumou Deng, Gen Wei, Wei Deng, Jianyong Ma, Wengen Zhu, Jiru Zhang, Shuchun Yu,
https://doi.org/10.18632/aging.104146 pp 25452—25468
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Tumor necrosis factor superfamily 14 is critical for the development of renal fibrosis

You Li, Ming Tang, Bo Han, Shun Wu, Shu-jing Li, Qian-hui He, Feng Xu, Gui-qing Li, Kun Zhang, Xu Cao, Quan-you Zheng, Jian Chen, Di Yang, Gui-lian Xu, Ke-qin Zhang,
https://doi.org/10.18632/aging.104151 pp 25469—25486
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Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits

Yu Wang, Yunxiao Kang, Chunxiao Qi, Tianyun Zhang, Hui Zhao, Xiaoming Ji, Wensheng Yan, Yuanxiang Huang, Rui Cui, Guoliang Zhang, Geming Shi,
https://doi.org/10.18632/aging.104155 pp 25487—25504
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Sesn2 attenuates the damage of endothelial progenitor cells induced by angiotensin II through regulating the Keap1/Nrf2 signal pathway

Shiao Ding, Nan Ma, Hao Liu, Min Tang, Ju Mei,
https://doi.org/10.18632/aging.104156 pp 25505—25527
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miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7

Fan Zhou, Wei Chen, Yinghong Cui, Bang Liu, Qingqing Yuan, Zheng Li, Zuping He,
https://doi.org/10.18632/aging.104158 pp 25528—25546
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LncRNA MAGI2-AS3 inhibits bladder cancer progression by targeting the miR-31-5p/TNS1 axis

Congyi Tang, Yi Cai, Huichuan Jiang, Zhengtong Lv, Changzhao Yang, Haozhe Xu, Zhi Li, Yuan Li,
https://doi.org/10.18632/aging.104162 pp 25547—25563
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TRIM27 acts as an oncogene and regulates cell proliferation and metastasis in non-small cell lung cancer through SIX3-β-catenin signaling

Shiyuan Liu, Ying Tian, Ying Zheng, Yao Cheng, Danjie Zhang, Jiantao Jiang, Shaomin Li,
https://doi.org/10.18632/aging.104163 pp 25564—25580
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A dual inhibitor targeting HMG-CoA reductase and histone deacetylase mitigates neurite degeneration in LRRK2-G2019S parkinsonism

Chin-Hsien Lin, Han-Yi Lin, Jim-Min Fang, Ching-Chow Chen,
https://doi.org/10.18632/aging.104165 pp 25581—25598
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Silencing hTERT attenuates cancer stem cell-like characteristics and radioresistance in the radioresistant nasopharyngeal carcinoma cell line CNE-2R

Kaihua Chen, Ling Li, Song Qu, Xinbin Pan, Yongchu Sun, Fangzhu Wan, Binbin Yu, Lei Zhou, Xiaodong Zhu,
https://doi.org/10.18632/aging.104167 pp 25599—25613
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Identification of prognostic chromatin-remodeling genes in clear cell renal cell carcinoma

Yujing Yang, Chengyuan Wang, Ningde Wei, Ting Hong, Zuyu Sun, Jiawen Xiao, Jiaxi Yao, Zhi Li, Tao Liu,
https://doi.org/10.18632/aging.104170 pp 25614—25642
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Neurofilament degradation is involved in laparotomy-induced cognitive dysfunction in aged rats

Yiyun Cao, Taotao Liu, Zhengqian Li, Jiao Yang, Lijun Ma, Xinning Mi, Ning Yang, Aihua Qi, Xiangyang Guo, Aizhong Wang,
https://doi.org/10.18632/aging.104172 pp 25643—25657
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Up-regulation of circRNA-0003528 promotes mycobacterium tuberculosis associated macrophage polarization via down-regulating miR-224-5p, miR-324-5p and miR-488-5p and up-regulating CTLA4

Zikun Huang, Fangyi Yao, Jun Liu, Jianqing Xu, Yang Guo, Rigu Su, Qing Luo, Junming Li,
https://doi.org/10.18632/aging.104175 pp 25658—25672
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Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b+Ly6G- myeloid cells

Yixuan Fang, Yue Gu, Lei Li, Lingjiang Zhu, Jiawei Qian, Chen Zhao, Li Xu, Wen Wei, Yanhua Du, Na Yuan, Suping Zhang, Ye Yuan, Youjia Xu, Cizhong Jiang, Jianrong Wang,
https://doi.org/10.18632/aging.104176 pp 25673—25683
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A SNP involved in alternative splicing of ABCB1 is associated with clopidogrel resistance in coronary heart disease in Chinese population

Shasha Zhang, Jing Wang, Anan Zhang, Xiaowei Zhang, Tao You, Dingxiong Xie, Wenke Yang, Yuhong Chen, Xuetian Zhang, Cuixia Di, Xiaodong Xie,
https://doi.org/10.18632/aging.104177 pp 25684—25699
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Inhibition of PAR-1 delays aging via activating AMPK in C. elegans

Di Wu, Waijiao Cai, Xuan Zhang, Jianfeng Lan, Lina Zou, Samuel J. Chen, Zixing Wu, Di Chen,
https://doi.org/10.18632/aging.104180 pp 25700—25717
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Central motor conduction time in spinocerebellar ataxia: a meta-analysis

Zhi-Chao Tang, Zhao Chen, Yu-Ting Shi, Lin-Lin Wan, Ming-Jie Liu, Xuan Hou, Chun-Rong Wang, Hui-Rong Peng, Lin-Liu Peng, Rong Qiu, Bei-Sha Tang, Hong Jiang,
https://doi.org/10.18632/aging.104181 pp 25718—25729
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Cardamonin induces G2/M phase arrest and apoptosis through inhibition of NF-κB and mTOR pathways in ovarian cancer

Jiang Ruibin, Jin Bo, Wan Danying, Feng Jianguo, Gu Linhui,
https://doi.org/10.18632/aging.104184 pp 25730—25743
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Alisol B 23-acetate activates ABCG5/G8 in the jejunum via the LXRα/ACAT2 pathway to relieve atherosclerosis in ovariectomized ApoE-/- mice

Xi-Chao Yu, Yu Fu, Yun-Hui Bi, Wei-Wei Zhang, Jun Li, Tingting Ji, Ying Chao, Qing-Hai Meng, Qi Chen, Meng-Hua Ma, Yu-Han Zhang, Jinjun Shan, Hui-Min Bian,
https://doi.org/10.18632/aging.104185 pp 25744—25766
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Zinc oxide nanoparticles (ZnO NPs) combined with cisplatin and gemcitabine inhibits tumor activity of NSCLC cells

Chenping Hu, Wenxiu Du,
https://doi.org/10.18632/aging.104187 pp 25767—25777
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Identification of prognostic aging-related genes associated with immunosuppression and inflammation in head and neck squamous cell carcinoma

Jing Yang, Qingshan Jiang, Lijun Liu, Hong Peng, Yaya Wang, Shuyan Li, Yanhua Tang, Jing Yu, Runliang Gan, Zhifeng Liu,
https://doi.org/10.18632/aging.104199 pp 25778—25804
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MRI-visible perivascular spaces are associated with cerebrospinal fluid biomarkers in Parkinson’s disease

Yi Fang, Lu-Yan Gu, Jun Tian, Shao-Bing Dai, Ying Chen, Ran Zheng, Xiao-Li Si, Chong-Yao Jin, Zhe Song, Ya-Ping Yan, Xin-Zhen Yin, Jia-Li Pu, Bao-Rong Zhang,
https://doi.org/10.18632/aging.104200 pp 25805—25818
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Association and functional study between ADIPOQ and metabolic syndrome in elderly Chinese Han population

Qiao Wang, Decheng Ren, Yan Bi, Ruixue Yuan, Dong Li, Jianying Wang, Ruirui Wang, Lei Zhang, Guang He, Baocheng Liu,
https://doi.org/10.18632/aging.104203 pp 25819—25827
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A glycolysis-related gene signature predicts prognosis of patients with esophageal adenocarcinoma

Huafeng Kang, Nan Wang, Xuan Wang, Yu Zhang, Shuai Lin, Guochao Mao, Di Liu, Chengxue Dang, Zhangjian Zhou,
https://doi.org/10.18632/aging.104206 pp 25828—25844
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The long noncoding RNA LINC01140/miR-140-5p/FGF9 axis modulates bladder cancer cell aggressiveness and macrophage M2 polarization

Shuiqing Wu, Ran Xu, Xuan Zhu, Haiqing He, Jinhua Zhang, Qi Zeng, Yinhuai Wang, Xiaokun Zhao,
https://doi.org/10.18632/aging.202147 pp 25845—25864
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Downregulation of enhancer RNA EMX2OS is associated with poor prognosis in kidney renal clear cell carcinoma

Huiming Jiang, Haibin Chen, Pei Wan, Shengda Song, Nanhui Chen,
https://doi.org/10.18632/aging.202151 pp 25865—25877
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Upregulation of KIF20A promotes tumor proliferation and invasion in renal clear cell carcinoma and is associated with adverse clinical outcome

Xiaohan Ren, Xinglin Chen, Yisheng Ji, Lin Li, Yunxin Li, Chao Qin, Kai Fang,
https://doi.org/10.18632/aging.202153 pp 25878—25894
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Effect of menopausal status on the survival and recurrence of sex-classified hepatocellular carcinoma after liver resection: a case-matched study with propensity score matching

Wenli Zhang, Fuchen Liu, Jian Huang, Xinggang Guo, Wei Dong, Shuxun Wei, Li Li, Xiuli Zhu, Weiping Zhou, Hui Liu,
https://doi.org/10.18632/aging.202155 pp 25895—25915
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Exploring diagnostic m6A regulators in endometriosis

Li Jiang, Mengmeng Zhang, Jingni Wu, Sixue Wang, Xiang Yang, Mingyu Yi, Xinyue Zhang, Xiaoling Fang,
https://doi.org/10.18632/aging.202163 pp 25916—25938
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Sexual dimorphism in aging hematopoiesis: an earlier decline of hematopoietic stem and progenitor cells in male than female mice

Eui-Young So, Euy-Myoung Jeong, Keith Q. Wu, Patrycja M. Dubielecka, Anthony M. Reginato, Peter J. Quesenberry, Olin D. Liang,
https://doi.org/10.18632/aging.202167 pp 25939—25955
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Periodontitis in elderly patients with type 2 diabetes mellitus: impact on gut microbiota and systemic inflammation

Jinyou Li, Haifeng Lu, Huanwen Wu, Shunmei Huang, Lufang Chen, Qifeng Gui, Wenjing Zhou, Yichen Yang, Yue Wu, Hua Zhang, Qin Zhang, Yunmei Yang,
https://doi.org/10.18632/aging.202174 pp 25956—25980
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Profilin 2 promotes growth, metastasis, and angiogenesis of small cell lung cancer through cancer-derived exosomes

Qi Cao, Yihan Liu, Ying Wu, Caijiao Hu, Lei Sun, Jinghui Wang, Changlong Li, Meng Guo, Xin Liu, Jianyi Lv, Xueyun Huo, Junming Yue, Xiaoyan Du, Zhenwen Chen,
https://doi.org/10.18632/aging.202213 pp 25981—25999
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Suppression of long noncoding RNA LINC00324 restricts cell proliferation and invasion of papillary thyroid carcinoma through downregulation of TRIM29 via upregulating microRNA-195-5p

Jinkai Xu, Zongyu Li, Qinghua Su, Jun Zhao, Jiancang Ma,
https://doi.org/10.18632/aging.202219 pp 26000—26011
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Decreased testosterone secretion index and free testosterone level with multiple symptoms for late-onset hypogonadism identification: a nationwide multicenter study with 5980 aging males in China

Honggang Li, Yiqun Gu, Xuejun Shang, Yuanzhong Zhou, Huiping Zhang, Liandong Zuo, Guangan Mei, Wei Xia, Huangtao Guan, Wenpei Xiang, Shanjie Zhou, Changchun Wan, Baojin Hao, Xubo Shen, Linguo Tang, Weixiong Wu, Ying Qi, Na Yu, Xiangbin Kong, Yaoping Chen, Yihong Yang, Xingrong Qing, Chengliang Xiong,
https://doi.org/10.18632/aging.202227 pp 26012—26028
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DUSP5 suppresses interleukin-1β-induced chondrocyte inflammation and ameliorates osteoarthritis in rats

Zhipeng Wu, Langhai Xu, Yuzhe He, Kai Xu, Zhonggai Chen, Safwat Adel Abdo Moqbel, Chiyuan Ma, Lifeng Jiang, Jisheng Ran, Lidong Wu, Ying Zhong,
https://doi.org/10.18632/aging.202252 pp 26029—26046
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6-Bromoindirubin-3’-oxime (6BIO) prevents myocardium from aging by inducing autophagy

Donghao Guo, Lizhen Cheng, Yun Shen, Wei Li, Qinjie Li, Yuan Zhong, Ya Miao,
https://doi.org/10.18632/aging.202253 pp 26047—26062
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An Immuno-Clinic score model for evaluating T cell immunity and predicting early antiviral therapy effectiveness in chronic hepatitis B

Yurong Gu, Xiaoyan Li, Lin Gu, Yifan Lian, Ke Wang, Youming Chen, Jing Lai, Yongyu Mei, Jing Liu, Zexuan Huang, Min Zhang, Lubiao Chen, Yuehua Huang,
https://doi.org/10.18632/aging.202274 pp 26063—26079
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Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism

Qun-yan Xiang, Feng Tian, Xiao Du, Jin Xu, Li-yuan Zhu, Li-ling Guo, Tie Wen, You-shuo Liu, Ling Liu,
https://doi.org/10.18632/aging.202298 pp 26080—26094
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Identification and validation of an immune-related gene signature predictive of overall survival in colon cancer

Xuening Zhang, Hao Zhao, Xuezhong Shi, Xiaocan Jia, Yongli Yang,
https://doi.org/10.18632/aging.202317 pp 26095—26120
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Subanesthetic isoflurane abates ROS-activated MAPK/NF-κB signaling to repress ischemia-induced microglia inflammation and brain injury

Zhiqiang Yao, Ningning Liu, Xiaoshan Zhu, Ling Wang, Yali Zhao, Qinqin Liu, Chunfang Gao, Juntang Li,
https://doi.org/10.18632/aging.202349 pp 26121—26139
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Role of electrocardiographic early repolarization pattern in long-term outcomes of a community-based middle-aged and geriatric ambulatory population: a prospective cohort study

Jyh-Ming Jimmy Juang, Yu-Jyun Huang, I-Shou Chang, Ching-Yu Julius Chen, I-Chien Wu, Chih-Cheng Hsu, Tzu-Yu Chen, Wei-Ting Tseng, Shih-Fan Sherri Yeh, Chao Agnes Hsiung,
https://doi.org/10.18632/aging.202369 pp 26140—26187
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MiR-223/NFAT5 signaling suppresses arterial smooth muscle cell proliferation and motility in vitro

Feifei Su, Miaoqian Shi, Jian Zhang, Qiangsun Zheng, Haichang Wang, Xue Li, Jianghong Chen,
https://doi.org/10.18632/aging.202395 pp 26188—26198
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Ring finger protein 2 promotes colorectal cancer progression by suppressing early growth response 1

Feilong Wei, Haoren Jing, Ming Wei, Lei Liu, Jieheng Wu, Meng Wang, Donghui Han, Fa Yang, Bo Yang, Dian Jiao, Guoxu Zheng, Lingling Zhang, Wenjin Xi, Zhangyan Guo, An-Gang Yang, Weijun Qin, Yi Zhou, Weihong Wen,
https://doi.org/10.18632/aging.202396 pp 26199—26220
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Construction and analysis of a joint diagnosis model of random forest and artificial neural network for heart failure

Yuqing Tian, Jiefu Yang, Ming Lan, Tong Zou,
https://doi.org/10.18632/aging.202405 pp 26221—26235
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Exosomal linc-FAM138B from cancer cells alleviates hepatocellular carcinoma progression via regulating miR-765

Chenyi Zhuo, Tingzhuang Yi, Jian Pu, Xiaoning Cen, Yang Zhou, Shi Feng, Cheng Wei, Pengyu Chen, Wei Wang, Chongchan Bao, Jianchu Wang, Qianli Tang,
https://doi.org/10.18632/aging.202430 pp 26236—26247
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Reviews

COVID-19
Influence of aging on deterioration of patients with COVID-19

Limin Pang, Yi Liu, Maoze Shen, Jujian Ye, Ruirong Chen, Zhien Lan, Zhijian Wu, Yang Guo, Peidong Zhang,
https://doi.org/10.18632/aging.202136 pp 26248—26262
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COVID-19
Immunometabolism at the cornerstone of inflammaging, immunosenescence, and autoimmunity in COVID-19

Loukman Omarjee, Frédérique Perrot, Olivier Meilhac, Guillaume Mahe, Guilhem Bousquet, Anne Janin,
https://doi.org/10.18632/aging.202422 pp 26263—26278
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Correction

Correction for: Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation

Fan Ouyang, Xiangyang Liu, Guoan Liu, Haihua Qiu, Yi He, Hongyu Hu, Ping Jiang,
https://doi.org/10.18632/aging.104222 pp 26279
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