Garik V. Mkrtchyan1Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark, Kotb Abdelmohsen2Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA, Pénélope Andreux3Amazentis SA, EPFL Innovation Park, Bâtiment C, Lausanne, Switzerland, Ieva Bagdonaite4Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark, Nir Barzilai5,Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA6Institute for Aging Research, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA, Søren Brunak7Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark, Filipe Cabreiro8Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, London, W12 0NN, UK, Rafael de Cabo9Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA, Judith Campisi10Buck Institute for Research on Aging, Novato, CA 94945, USA, Ana Maria Cuervo11Department of Developmental and Molecular Biology, Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, NY 10461, USA, Marco Demaria12European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, The Netherlands, Collin Y. Ewald13Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute for Technology Zürich, Switzerland, Evandro Fei Fang14Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478 Lørenskog, Norway, Richard Faragher15School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK, Luigi Ferrucci16Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA, Adam Freund17Calico Life Sciences, LLC, South San Francisco, CA 94080, USA, Carlos G. Silva-García18Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA, Anastasia Georgievskaya19HautAI OÜ, Tallinn, Estonia, Vadim N. Gladyshev20Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA, David J. Glass21Regeneron Pharmaceuticals, Inc. Tarrytown, NY 10591, USA, Vera Gorbunova22Departments of Biology and Medicine, University of Rochester, Rochester, NY 14627, USA, Aubrey de Grey23SENS Research Foundation, Mountain View, CA 94041, USA, Wei-Wu He24Human Longevity Inc., San Diego, CA 92121, USA, Jan Hoeijmakers25Department of Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands, Eva Hoffmann26DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, Steve Horvath27Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA, Riekelt H. Houtkooper28Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands, Majken K. Jensen29Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark, Martin Borch Jensen30Gordian Biotechnology, San Francisco, CA 94107, USA, Alice Kane31Blavatnik Institute, Department of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, MA 94107, USA, Moustapha Kassem32Molecular Endocrinology Unit, Department of Endocrinology, University Hospital of Odense and University of Southern Denmark, Odense, Denmark, Peter de Keizer33Department of Molecular Cancer Research, Center for Molecular Medicine, Division of Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands, Brian Kennedy10,Buck Institute for Research on Aging, Novato, CA 94945, USA34,Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University Singapore, Singapore35Centre for Healthy Ageing, National University Healthy System, Singapore, Gerard Karsenty36Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA, Dudley W. Lamming37Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53792, USA, Kai-Fu Lee38Sinovation Ventures and Sinovation AI Institute, Beijing, China, Nanna MacAulay39Department of Neuroscience, University of Copenhagen, Denmark, Polina Mamoshina40Deep Longevity Inc., Hong Kong Science and Technology Park, Hong Kong, Jim Mellon41Juvenescence Limited, Douglas, Isle of Man, UK, Marte Molenaars28Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands, Alexey Moskalev42Institute of Biology of FRC Komi Science Center of Ural Division of RAS, Syktyvkar, Russia, Andreas Mund7Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark, Laura Niedernhofer43Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA, Brenna Osborne1Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark, Heidi H. Pak37Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53792, USA, Andrey Parkhitko44University of Pittsburgh, Pittsburgh, PA 15260, USA, Nuno Raimundo45Institute of Cellular Biochemistry, University Medical Center Goettingen, Goettingen, Germany, Thomas A. Rando46Department of Neurology and Neurological Sciences and Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305, USA, Lene Juel Rasmussen1Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark, Carolina Reis47OneSkin Inc., San Francisco, CA 94107, USA, Christian G. Riedel48Department of Biosciences and Nutrition, Karolinska Institute, Stockholm, Sweden, Anais Franco-Romero49Department of Biomedical Sciences, University of Padova, Italy, Björn Schumacher50Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany, David A. Sinclair31,Blavatnik Institute, Department of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, MA 94107, USA51Department of Pharmacology, School of Medical Sciences, The University of New South Wales, Sydney, NSW, Australia, Yousin Suh52Departments of Obstetrics and Gynecology, Genetics and Development, Columbia University, New York, NY 10027, USA, Pam R. Taub53Division of Cardiovascular Medicine, University of California, San Diego, CA 92093, USA, Debra Toiber54Department of Life Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel, Jonas T. Treebak55Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark, Dario Riccardo Valenzano56Max Planck Institute for Biology of Ageing, Cologne, Germany, Eric Verdin10Buck Institute for Research on Aging, Novato, CA 94945, USA, Jan Vijg5Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA, Sergey Young57Longevity Vision Fund, New York, NY 10022, USA, Lei Zhang43Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA, Daniela Bakula1Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark, Alex Zhavoronkov58Insilico Medicine, Hong Kong Science and Technology Park, Hong Kong, Morten Scheibye-Knudsen1Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark
- 1Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark
- 2Laboratory of Genetics and Genomics, National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD 21224, USA
- 3Amazentis SA, EPFL Innovation Park, Bâtiment C, Lausanne, Switzerland
- 4Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark
- 5Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- 6Institute for Aging Research, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- 7Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark
- 8Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, London, W12 0NN, UK
- 9Experimental Gerontology Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
- 10Buck Institute for Research on Aging, Novato, CA 94945, USA
- 11Department of Developmental and Molecular Biology, Institute for Aging Studies, Albert Einstein College of Medicine, Bronx, NY 10461, USA
- 12European Research Institute for the Biology of Ageing, University Medical Center Groningen, University of Groningen, The Netherlands
- 13Institute of Translational Medicine, Department of Health Sciences and Technology, Swiss Federal Institute for Technology Zürich, Switzerland
- 14Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, 1478 Lørenskog, Norway
- 15School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK
- 16Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA
- 17Calico Life Sciences, LLC, South San Francisco, CA 94080, USA
- 18Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA
- 19HautAI OÜ, Tallinn, Estonia
- 20Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA
- 21Regeneron Pharmaceuticals, Inc. Tarrytown, NY 10591, USA
- 22Departments of Biology and Medicine, University of Rochester, Rochester, NY 14627, USA
- 23SENS Research Foundation, Mountain View, CA 94041, USA
- 24Human Longevity Inc., San Diego, CA 92121, USA
- 25Department of Genetics, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
- 26DNRF Center for Chromosome Stability, Department of Cellular and Molecular Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
- 27Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
- 28Laboratory Genetic Metabolic Diseases, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands
- 29Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
- 30Gordian Biotechnology, San Francisco, CA 94107, USA
- 31Blavatnik Institute, Department of Genetics, Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School, Boston, MA 94107, USA
- 32Molecular Endocrinology Unit, Department of Endocrinology, University Hospital of Odense and University of Southern Denmark, Odense, Denmark
- 33Department of Molecular Cancer Research, Center for Molecular Medicine, Division of Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
- 34Departments of Biochemistry and Physiology, Yong Loo Lin School of Medicine, National University Singapore, Singapore
- 35Centre for Healthy Ageing, National University Healthy System, Singapore
- 36Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA
- 37Department of Medicine, University of Wisconsin-Madison and William S. Middleton Memorial Veterans Hospital, Madison, WI 53792, USA
- 38Sinovation Ventures and Sinovation AI Institute, Beijing, China
- 39Department of Neuroscience, University of Copenhagen, Denmark
- 40Deep Longevity Inc., Hong Kong Science and Technology Park, Hong Kong
- 41Juvenescence Limited, Douglas, Isle of Man, UK
- 42Institute of Biology of FRC Komi Science Center of Ural Division of RAS, Syktyvkar, Russia
- 43Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
- 44University of Pittsburgh, Pittsburgh, PA 15260, USA
- 45Institute of Cellular Biochemistry, University Medical Center Goettingen, Goettingen, Germany
- 46Department of Neurology and Neurological Sciences and Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305, USA
- 47OneSkin Inc., San Francisco, CA 94107, USA
- 48Department of Biosciences and Nutrition, Karolinska Institute, Stockholm, Sweden
- 49Department of Biomedical Sciences, University of Padova, Italy
- 50Institute for Genome Stability in Ageing and Disease, Medical Faculty, University of Cologne, Cologne, Germany
- 51Department of Pharmacology, School of Medical Sciences, The University of New South Wales, Sydney, NSW, Australia
- 52Departments of Obstetrics and Gynecology, Genetics and Development, Columbia University, New York, NY 10027, USA
- 53Division of Cardiovascular Medicine, University of California, San Diego, CA 92093, USA
- 54Department of Life Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel
- 55Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark
- 56Max Planck Institute for Biology of Ageing, Cologne, Germany
- 57Longevity Vision Fund, New York, NY 10022, USA
- 58Insilico Medicine, Hong Kong Science and Technology Park, Hong Kong