Volume 1, Issue 2

February 2009pp 146—274

Perspective

Is thymocyte development functional in the aged?

Danielle Aw, Alberto B. Silva, Donald B. Palmer

https://doi.org/10.18632/aging.100027pp 146—153

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Endogenous DNA breaks: γH2AX and the role of telomeres

Peggy L. Olive

https://doi.org/10.18632/aging.100025pp 154—156

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Reviews

Immune physiology in tissue regeneration and aging, tumor growth, and regenerative medicine

Antonin Bukovsky, Michael R. Caudle, Ray J. Carson, Francisco Gaytán, Mahmoud Huleihel, Andrea Kruse, Heide Schatten, Carlos M. Telleria

https://doi.org/10.18632/aging.100024pp 157—181

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Chromatin modifications: The driving force of senescence and aging?

Teresa DiMauro, Gregory David

https://doi.org/10.18632/aging.100023pp 182—190

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Research Papers

A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila

Jie Shen, Christina Curtis, Simon Tavaré, John Tower

https://doi.org/10.18632/aging.100018pp 191—211

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Telomere-dependent and telomere-independent origins of endogenous DNA damage in tumor cells

Asako J. Nakamura, Christophe E. Redon, William M. Bonner, Olga A. Sedelnikova

https://doi.org/10.18632/aging.100019pp 212—218

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WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3

Monika Aggarwal, Robert M. Brosh

https://doi.org/10.18632/aging.100020pp 219—233

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Cyclooxygenase-1 null mice show reduced neuroinflammation in response to β-amyloid

Sang-Ho Choi, Francesca Bosetti

https://doi.org/10.18632/aging.100021pp 234—244

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Knockout of Ku86 accelerates cellular senescence induced by high NaCl

Natalia I. Dmitrieva, Hua Tang Chen, André Nussenzweig, Maurice B. Burg

https://doi.org/10.18632/aging.100022pp 245—253

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Identification of Peroxiredoxin 1 as a novel interaction partner for the lifespan regulator protein p66Shc

Melanie Gertz, Frank Fischer, Martina Leipelt, Dirk Wolters, Clemens Steegborn

https://doi.org/10.18632/aging.100017pp 254—265

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Positive association of common variants in CD36 with neovascular age-related macular degeneration

Naoshi Kondo, Shigeru Honda, Shin-ichi Kuno, Akira Negi

https://doi.org/10.18632/aging.100006pp 266—274

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