Volume 4, Issue 1

January 2012pp 1—73

Editorial

Starting 2012: Sod2, DGAT1, p53, SPARC, QTL and reprogramming in aging

https://doi.org/10.18632/aging.100429pp 1

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Editorial Interview

Interview with Michael Ristow

https://doi.org/10.18632/aging.100430pp 2

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Research Papers

Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin

Michael C. Velarde, James M. Flynn, Nicholas U. Day, Simon Melov, Judith Campisi

https://doi.org/10.18632/aging.100423pp 3—12

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Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice

Ryan S. Streeper, Carrie A. Grueter, Nathan Salomonis, Sylvaine Cases, Malin C. Levin, Suneil K. Koliwad, Ping Zhou, Matthew D. Hirschey, Eric Verdin, Robert V. Farese Jr.

https://doi.org/10.18632/aging.100424pp 13—27

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TP53 codon 72 polymorphism affects accumulation of mtDNA damage in human cells

Serena Altilia, Aurelia Santoro, Davide Malagoli, Catia Lanzarini, Josué Adolfo Ballesteros Álvarez, Gianluca Galazzo, Donald Carl Porter, Paolina Crocco, Giuseppina Rose, Giuseppe Passarino, Igor Boris Roninson, Claudio Franceschi, Stefano Salvioli

https://doi.org/10.18632/aging.100425pp 28—39

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Age-related resistance of skeletal muscle-derived progenitor cells to SPARC may explain a shift from myogenesis to adipogenesis

Serena Katsuyuki Nakamura, Shin-ichi Nakano, Takahiro Miyoshi, Keitaro Yamanouchi, Takashi Matsuwaki, Masugi Nishihara

https://doi.org/10.18632/aging.100426pp 40—48

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Quantitative trait loci on chromosome 1 for cataract and AMD-like retinopathy in senescence-accelerated OXYS rats

Elena E. Korbolina, Ouyna S. Kozhevnikova, Nataliya A. Stefanova, Natalia G. Kolosova

https://doi.org/10.18632/aging.100427pp 49—59

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Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency

Seiga Ohmine, Karen A. Squillace, Katherine A. Hartjes, Michael C. Deeds, Adam S. Armstrong, Tayaramma Thatava, Toshie Sakuma, Andre Terzic, Yogish Kudva, Yasuhiro Ikeda

https://doi.org/10.18632/aging.100428pp 60—73

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