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• Research PaperVolume 14, Issue 19pp 8077-8094

  Novel small molecular compound 2JY-OBZ4 alleviates AD pathology in cell models via regulating multiple targets

  Relevance score: 0.00

  Qian Guo, Gang Wu, Fang Huang, Zhen Wei, Jian-Zhi Wang, Bin Zhang, Rong Liu, Yang Yang, Xiaochuan Wang, Hong-Lian Li

  Keywords: Alzheimer’s disease (AD), Huperzine A (Hup-A), beta-secretase 1 (BACE1), protein phosphatase- 2A (PP2A), cholinesterase inhibitor

  Published in Aging on October 12, 2022

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• Research PaperVolume 13, Issue 14pp 18993-19012

  A network pharmacology approach to uncover the key ingredients in Ginkgo Folium and their anti-Alzheimer’s disease mechanisms

  Relevance score: 0.00

  Peng Zeng, Meng Fang, Han Zhao, Jing Guo

  Keywords: Alzheimer’s disease, Ginkgo Folium, network pharmacology, genkwanin, AD pathology

  Published in Aging on July 27, 2021

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• Research PaperVolume 17, Issue 5pp 1105-1138

  APOE genotype and biological age impact inter-omic associations related to bioenergetics

  Relevance score: 0.00

  Dylan Ellis, Kengo Watanabe, Tomasz Wilmanski, Michael S. Lustgarten, Andres V. Ardisson Korat, Gwênlyn Glusman, Jennifer Hadlock, Oliver Fiehn, Paola Sebastiani, Nathan D. Price, Leroy Hood, Andrew T. Magis, Simon J. Evans, Lance Pflieger, Jennifer C. Lovejoy, Sean M. Gibbons, Cory C. Funk, Priyanka Baloni, Noa Rappaport

  Keywords: apolipoprotein E (APOE), biological age, metabolism, Alzheimer’s disease (AD), insulin resistance

  Published in Aging on May 3, 2025

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• Research PaperVolume 16, Issue 3pp 1983-2004

  GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects

  Relevance score: 0.00

  Hyun-Hee Park, Hyuk Sung Kwon, Kyu-Yong Lee, Ye Eun Kim, Jeong-Woo Son, Na-Young Choi, Myung-Hoon Han, Dong Woo Park, Sangjae Kim, Seong-Ho Koh

  Keywords: 3xTg-AD mice, GV1001, neurodegeneration, anti-aging, Alzheimer’s disease

  Published in Aging on January 31, 2024

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• Research PaperVolume 17, Issue 11pp 2664-2687

  Infusion of blood from young and old mice modulates amyloid pathology

  Relevance score: 0.00

  Matias Pizarro, Ruben Gomez-Gutierrez, Ariel Caviedes, Catalina Valdes, Ute Woehlbier, Cristian Vargas, Mauricio Hernandez, Claudia Duran-Aniotz, Rodrigo Morales

  Keywords: Alzheimer’s disease, amyloid-β, neurodegeneration, protein misfolding, blood infusion, therapeutic targets

  Published in Aging on September 12, 2025

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• Research PaperVolume 16, Issue 21pp 13340-13355

  Identification of the m6A/m5C/m1A methylation modification genes in Alzheimer’s disease based on bioinformatic analysis

  Relevance score: 0.00

  Qifa Tan, Desheng Zhou, Yuan Guo, Haijun Chen, Peng Xie

  Keywords: Alzheimer’s disease, cluster analysis, machine learning, immune characteristics, diagnostic model

  Published in Aging on October 31, 2024

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• Research PaperVolume 16, Issue 10pp 9216-9227

  The protective effects of Chromofungin in oligomeric amyloid β₄₂ (Aβ₄₂)-induced toxicity in neurons in Alzheimer’s disease

  Relevance score: 0.00

  Qingwei Li, Ji Sun, Qin Ran, Ziming Liu, Jinmei Chen

  Keywords: Alzheimer’s disease, Chromofungin, senescence, oxidative stress, oligomeric Aβ₄₂

  Published in Aging on May 24, 2024

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• Research PaperVolume 16, Issue 10pp 9072-9105

  Sensitivity of substrate translocation in chaperone-mediated autophagy to Alzheimer’s disease progression

  Relevance score: 0.00

  Lei Yu, Xinping Pang, Lin Yang, Kunpei Jin, Wenbo Guo, Yanyu Wei, Chaoyang Pang

  Keywords: Alzheimer’s disease, chaperone-mediated autophagy, lysosome, GFAP

  Published in Aging on May 23, 2024

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• Research PaperVolume 16, Issue 2pp 1374-1389

  Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis

  Relevance score: 0.00

  Shunling Yuan, Yirong Wang, Jialun Yang, Yingzhe Tang, Weijia Wu, Xiangyuan Meng, Ye Jian, Yong Lei, Yang Liu, Changfa Tang, Zhe Zhao, Fei Zhao, Wenfeng Liu

  Keywords: Alzheimer’s disease, treadmill exercise, hepatic oxidative stress, intestinal-liver axis, Kupffer cells

  Published in Aging on January 29, 2024

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• Research PaperVolume 15, Issue 22pp 13239-13264

  Qi Fu Yin ameliorates neuroinflammation through inhibiting RAGE and TLR4/NF-κB pathway in AD model rats

  Relevance score: 0.00

  Chunxiang He, Wenjing Yu, Miao Yang, Ze Li, Jingping Yu, Dayuan Zhong, Sisi Deng, Zhenyan Song, Shaowu Cheng

  Keywords: Alzheimer’s disease, traditional Chinese medicine, neuroinflammation, RAGE, TLR4/NF-κB signaling pathway

  Published in Aging on November 22, 2023

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• Research PaperVolume 15, Issue 22pp 13077-13099

  Identification of tryptophan metabolism-related genes in immunity and immunotherapy in Alzheimer’s disease

  Relevance score: 0.00

  Zhenyan Song, Zixuan Wu, Rongsiqing Luo, Chunxiang He, Ze Li, Miao Yang, Wenjing Yu, Jiawei He, Sisi Deng, Shaowu Cheng

  Keywords: Alzheimer’s disease, tryptophan metabolism-related genes, DEGs, WGCNA, bioinformatics

  Published in Aging on November 20, 2023

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• Research PaperVolume 15, Issue 21pp 12085-12103

  Identification and diagnostic potential of serum microRNAs as biomarkers for early detection of Alzheimer’s disease

  Relevance score: 0.00

  Ying-Hao Han, Hong-Yi Xiang, Dong Hun Lee, Lin Feng, Hu-Nan Sun, Mei-Hua Jin, Taeho Kwon

  Keywords: Alzheimer’s disease, serum, microRNA, diagnostic models, biomarkers

  Published in Aging on November 1, 2023

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• Research PaperVolume 15, Issue 19pp 10389-10406

  Novel diagnostic biomarkers of oxidative stress, immunological characterization and experimental validation in Alzheimer’s disease

  Relevance score: 0.00

  Di Hu, Xiaocong Mo, Luo Jihang, Cheng Huang, Hesong Xie, Ling Jin

  Keywords: Alzheimer’s disease, oxidative stress, molecular clusters, prediction model, immune infiltration

  Published in Aging on October 5, 2023

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• Research PaperVolume 15, Issue 19pp 10237-10252

  Ginkgolide attenuates memory impairment and neuroinflammation by suppressing the NLRP3/caspase-1 pathway in Alzheimer’s disease

  Relevance score: 0.00

  Guang-Zhi Liu, Tian-Tong Niu, Qian Yu, Bao-Lei Xu, Xiao-Qing Li, Bo-Yi Yuan, Guo-Bin Yuan, Ting-Ting Yang, Hui-Qin Li, Yi Sun

  Keywords: Alzheimer’s disease, amyloid beta, ginkgolide, microglia, NLRP3 inflammasome

  Published in Aging on October 3, 2023

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• Research PaperVolume 15, Issue 9pp 3715-3737

  Plasmon-activated water as a therapeutic strategy in Alzheimer’s disease by altering gut microbiota

  Relevance score: 0.00

  Chia-Hsiung Cheng, Yu-Chuan Liu, Yu-Chen S.H. Yang, Kun-Ju Lin, Dean Wu, Yun-Ru Liu, Chun-Chao Chang, Chien-Tai Hong, Chaur-Jong Hu

  Keywords: Alzheimer’s disease, plasmon-activated water, fecal microbiota transplantation, microbiota, beta amyloid, tau

  Published in Aging on May 8, 2023

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• Research PaperVolume 15, Issue 6pp 2158-2169

  Reduction of NgR in perforant path protects neuronal morphology and function in APP/PS1 transgenic mice

  Relevance score: 0.00

  Rong Jiang, Xiao-Dong Chi, Yulong Jing, Bin Wang, Shao Li

  Keywords: Alzheimer’s disease, Nogo receptor, perforant path, neuron, synapse

  Published in Aging on March 23, 2023

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• Research PaperVolume 15, Issue 3pp 630-649

  Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice

  Relevance score: 0.00

  Diana M. Bessa de Sousa, Ariane Benedetti, Barbara Altendorfer, Heike Mrowetz, Michael S. Unger, Katharina Schallmoser, Ludwig Aigner, Kathrin Maria Kniewallner

  Keywords: Alzheimer’s disease, platelets, amyloid-beta, microglia, astrocytes

  Published in Aging on February 1, 2023

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• Research PaperVolume 15, Issue 2pp 459-471

  Characterizing the gut microbiome changes with aging in a novel Alzheimer’s disease rat model

  Relevance score: 0.00

  Akash Nagarajan, Hemant Srivastava, Casey D. Morrow, Liou Y. Sun

  Keywords: Alzheimer’s disease, gut microbiome, gut-brain axis, aging, F344 rats

  Published in Aging on January 13, 2023

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• Research PaperVolume 14, Issue 20pp 8221-8242

  AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy

  Relevance score: 0.00

  Paul Dent, Laurence Booth, Jane L. Roberts, Andrew Poklepovic, Jennifer Martinez, Derek Cridebring, Eric M. Reiman

  Keywords: Alzheimer’s disease, macroautophagy, LAP / LANDO, GRP78, AR12

  Published in Aging on October 13, 2022

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• Research PaperVolume 14, Issue 18pp 7568-7586

  Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity

  Relevance score: 0.00

  Ya-Jen Chiu, Te-Hsien Lin, Kuo-Hsuan Chang, Wenwei Lin, Hsiu Mei Hsieh-Li, Ming-Tsan Su, Chiung-Mei Chen, Ying-Chieh Sun, Guey-Jen Lee-Chen

  Keywords: Alzheimer’s disease, TRKB agonists, Aβ, neuroprotection, therapeutics

  Published in Aging on September 26, 2022

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