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The cover features Figure 1 "Rejuvenation by cell reprogramming of fibroblasts from healthy centenarian individuals“ from Chiavellini et al.

Volume 13, Issue 4

28 February, 2021
pp 4734—6230

About the Cover

The cover features Figure 1 "Rejuvenation by cell reprogramming of fibroblasts from healthy centenarian individuals“ from Chiavellini et al.


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Research Perspective

Aging and rejuvenation - a modular epigenome model

Priscila Chiavellini, Martina Canatelli-Mallat, Marianne Lehmann, Maria D. Gallardo, Claudia B. Herenu, Jose L. Cordeiro, James Clement, Rodolfo G. Goya,
https://doi.org/10.18632/aging.202712 pp 4734—4746
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Priority Research Papers

Insights into epithelial cell senescence from transcriptome and secretome analysis of human oral keratinocytes

Rachael E. Schwartz, Maxim N. Shokhirev, Leonardo R. Andrade, J. Silvio Gutkind, Ramiro Iglesias-Bartolome, Gerald S. Shadel,
https://doi.org/10.18632/aging.202658 pp 4747—4777
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A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells

Rajiv L. Tiwari, Pratibha Mishra, Nicola Martin, Nikhil Oommen George, Vadim Sakk, Karin Soller, Kodandaramireddy Nalapareddy, Kalpana Nattamai, Karin Scharffetter-Kochanek, Maria Carolina Florian, Hartmut Geiger,
https://doi.org/10.18632/aging.202694 pp 4778—4793
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Research Papers

COVID-19
Association of D-dimer elevation with inflammation and organ dysfunction in ICU patients with COVID-19 in Wuhan, China: a retrospective observational study

Wang Zhang, Ling Sang, Jiaran Shi, Ming Zhong, Li Jiang, Bin Song, Liang Kang, Yun Zhang, Dingyu Zhang, Yunsong Yu, Xia Zheng,
https://doi.org/10.18632/aging.202496 pp 4794—4810
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COVID-19
Chemical composition and pharmacological mechanism of ephedra-glycyrrhiza drug pair against coronavirus disease 2019 (COVID-19)

Xiaoling Li, Qin Qiu, Mingyue Li, Haowen Lin, Shilin Cao, Qu Wang, Zishi Chen, Wenhao Jiang, Wen Zhang, Yuge Huang, Hui Luo, Lianxiang Luo,
https://doi.org/10.18632/aging.202622 pp 4811—4830
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An aging and p53 related marker: HOXA5 promoter methylation negatively correlates with mRNA and protein expression in old age

Laura-Kim Feiner, Sascha Tierling, Sebastian Holländer, Matthias Glanemann, Claudia Rubie,
https://doi.org/10.18632/aging.202621 pp 4831—4849
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Metabolic footprint of aging and obesity in red blood cells

Inés Domingo-Ortí, Rubén Lamas-Domingo, Andreea Ciudin, Cristina Hernández, José Raúl Herance, Martina Palomino-Schätzlein, Antonio Pineda-Lucena,
https://doi.org/10.18632/aging.202693 pp 4850—4880
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MiR-141-3p promotes mitochondrial dysfunction in ovariectomy-induced sarcopenia via targeting Fkbp5 and Fibin

Hyunjung Lee, Young In Kim, Farida S. Nirmala, Ji-Sun Kim, Hyo-Deok Seo, Tae Youl Ha, Young-Jin Jang, Chang Hwa Jung, Jiyun Ahn,
https://doi.org/10.18632/aging.202617 pp 4881—4894
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Cholecalciferol (vitamin D3) has a direct protective activity against interleukin 6-induced atrophy in C2C12 myotubes

Maraiza Alves Teixeira, Marilisa De Feudis, Simone Reano, Tommaso Raiteri, Andrea Scircoli, Ivan Zaggia, Sara Ruga, Laura Salvadori, Flavia Prodam, Paolo Marzullo, Claudio Molinari, Davide Corà, Nicoletta Filigheddu,
https://doi.org/10.18632/aging.202669 pp 4895—4910
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Sex and age-related differences in cerebral blood flow investigated using pseudo-continuous arterial spin labeling magnetic resonance imaging

Joseph S. R. Alisch, Nikkita Khattar, Richard W. Kim, Luis E. Cortina, Abinand C. Rejimon, Wenshu Qian, Luigi Ferrucci, Susan M. Resnick, Richard G. Spencer, Mustapha Bouhrara,
https://doi.org/10.18632/aging.202673 pp 4911—4925
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Functional analysis of POLD1 p.ser605del variant: the aging phenotype of MDPL syndrome is associated with an impaired DNA repair capacity

Michela Murdocca, Paola Spitalieri, Claudia De Masi, Ion Udroiu, Jessica Marinaccio, Massimo Sanchez, Rosa Valentina Talarico, Chiara Fiorillo, Monica D’Adamo, Paolo Sbraccia, Maria Rosaria D’Apice, Giuseppe Novelli, Antonella Sgura, Federica Sangiuolo,
https://doi.org/10.18632/aging.202680 pp 4926—4945
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Fibroblasts from different body parts exhibit distinct phenotypes in adult progeria Werner syndrome

Hisaya Kato, Yoshiro Maezawa, Naoya Takayama, Yasuo Ouchi, Hiyori Kaneko, Daisuke Kinoshita, Aki Takada-Watanabe, Motohiko Oshima, Masaya Koshizaka, Hideyuki Ogata, Yoshitaka Kubota, Nobuyuki Mitsukawa, Koji Eto, Atsushi Iwama, Koutaro Yokote,
https://doi.org/10.18632/aging.202696 pp 4946—4961
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Methylation-dependent MCM6 repression induced by LINC00472 inhibits triple-negative breast cancer metastasis by disturbing the MEK/ERK signaling pathway

Guoli Shao, Xulong Fan, Pusheng Zhang, Xuewen Liu, Lei Huang, Shufeng Ji,
https://doi.org/10.18632/aging.103568 pp 4962—4975
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GPR173 agonist phoenixin 20 promotes osteoblastic differentiation of MC3T3-E1 cells

Zhengtao Gu, Denghui Xie, Rui Ding, Caiqiang Huang, Yiyan Qiu,
https://doi.org/10.18632/aging.103717 pp 4976—4985
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Loss of FBP1 promotes proliferation, migration, and invasion by regulating fatty acid metabolism in esophageal squamous cell carcinoma

Yi He, Rong Hua, Bin Li, Haiyong Gu, Yifeng Sun, Zhigang Li,
https://doi.org/10.18632/aging.103916 pp 4986—4998
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HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier

HongShan Zheng, ChenLong Li, ZhenZhe Li, KaiBin Zhu, HongBo Bao, JinSheng Xiong, Peng Liang,
https://doi.org/10.18632/aging.202324 pp 4999—5019
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Toxic effect of titanium dioxide nanoparticles on corneas in vitro and in vivo

Junxing Yang, Jianliang Liu, Ping Wang, Juanjuan Sun, Xiaohui Lv, Yumei Diao,
https://doi.org/10.18632/aging.202412 pp 5020—5033
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Transcriptional dysregulation of TRIM29 promotes colorectal cancer carcinogenesis via pyruvate kinase-mediated glucose metabolism

Jing Han, Zitong Zhao, Nan Zhang, Yang Yang, Liying Ma, Li Feng, Xue Zhang, Jing Zuo, Zhisong Fan, Yudong Wang, Yongmei Song, Guiying Wang,
https://doi.org/10.18632/aging.202414 pp 5034—5054
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MicroRNA-29a-3p delivery via exosomes derived from engineered human mesenchymal stem cells exerts tumour suppressive effects by inhibiting migration and vasculogenic mimicry in glioma

Zongpu Zhang, Xing Guo, Xiaofan Guo, Rui Yu, Mingyu Qian, Shaobo Wang, Xiao Gao, Wei Qiu, Qindong Guo, Jianye Xu, Zihang Chen, Huizhi Wang, Yanhua Qi, Rongrong Zhao, Hao Xue, Gang Li,
https://doi.org/10.18632/aging.202424 pp 5055—5068
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Inhibiting Th1/2 cells influences hepatic capillarization by adjusting sinusoidal endothelial fenestrae through Rho-ROCK-myosin pathway

Yuesi Zhong, Mingxing Xu, Jingxiong Hu, Xi Huang, Nan Lin, Meihai Deng,
https://doi.org/10.18632/aging.202425 pp 5069—5086
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Integrative transcriptomic and metabonomic profiling analyses reveal the molecular mechanism of Chinese traditional medicine huankuile suspension on TNBS-induced ulcerative colitis

Zhenglan Han, Hanyan Wang, Dongmei Guo, Jingping Zhang,
https://doi.org/10.18632/aging.202427 pp 5087—5103
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Prognostic value of an autophagy-related long-noncoding-RNA signature for endometrial cancer

Xiufang Wang, Chenyang Dai, Minqing Ye, Jingyun Wang, Weizhao Lin, Ruiman Li,
https://doi.org/10.18632/aging.202431 pp 5104—5119
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Identification of hub genes and key pathways in the emphysema phenotype of COPD

Qiunan Zuo, Youyu Wang, Deqing Yang, Shujin Guo, Xiaohui Li, Jiajia Dong, Chun Wan, Yongchun Shen, Fuqiang Wen,
https://doi.org/10.18632/aging.202432 pp 5120—5135
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Association between PPAR-γ2 gene polymorphisms and diabetic retinopathy risk: a meta-analysis

Xue-Feng Li, Guang-Bin Jiang, Shi-Yan Cheng, Ya-Feng Song, Cai Deng, Yu-Ming Niu, Jun-Wei Cai,
https://doi.org/10.18632/aging.202433 pp 5136—5149
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Nampt promotes osteogenic differentiation and lipopolysaccharide-induced interleukin-6 secretion in osteoblastic MC3T3-E1 cells

Shan He, Hanxiang Zhang, Yang Lu, Zhaosi Zhang, Xiang Zhang, Nian Zhou, Zhenming Hu,
https://doi.org/10.18632/aging.202434 pp 5150—5163
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Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway

Xian-Qiang Ni, Ya-Rong Zhang, Li-Xin Jia, Wei-Wei Lu, Qing Zhu, Jin-Ling Ren, Yao Chen, Lin-Shuang Zhang, Xin Liu, Yan-Rong Yu, Mo-Zhi Jia, Zhong-Ping Ning, Jie Du, Chao-Shu Tang, Yong-Fen Qi,
https://doi.org/10.18632/aging.202436 pp 5164—5184
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A short deletion in the DNA-binding domain of STAT3 suppresses growth and progression of colon cancer cells

Yi-Jia Xiong, Dong-Yang Liu, Rong-Rong Shen, Yong Xiong,
https://doi.org/10.18632/aging.202439 pp 5185—5196
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High expression of vinculin predicts poor prognosis and distant metastasis and associates with influencing tumor-associated NK cell infiltration and epithelial-mesenchymal transition in gastric cancer

Huafu Li, Chunming Wang, Linxiang Lan, Axel Behrens, Mona Tomaschko, Josue Ruiz, Qiao Su, Guangying Zhao, Cheng Yuan, Xing Xiao, Bo Li, Leping Yan, Wang Wu, Wuguo Li, Junzong Chen, Yulong He, Changhua Zhang,
https://doi.org/10.18632/aging.202440 pp 5197—5225
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Associations between smoking, sex hormone levels and late-onset hypogonadism in men differ depending on age

Qian Liu, Xiangchi Peng, Yiqun Gu, Xuejun Shang, Yuanzhong Zhou, Huiping Zhang, Liandong Zuo, Guangan Mei, Chengliang Xiong, Honggang Li, Xiangbin Kong,
https://doi.org/10.18632/aging.202442 pp 5226—5237
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A simple-to-use web-based calculator for survival prediction in Parkinson’s disease

Yunliang Tang, Jiao Wang, Gengfa Chen, Wen Ye, Nao Yan, Zhen Feng,
https://doi.org/10.18632/aging.202443 pp 5238—5249
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Clinical application values of neutrophil-to-lymphocyte ratio in intracranial aneurysms

Baorui Zhang, Lin Lin, Fei Yuan, Guangrong Song, Qing Chang, Zhongxue Wu, Zhongrong Miao, Dapeng Mo, Xiaochuan Huo, Aihua Liu,
https://doi.org/10.18632/aging.202445 pp 5250—5262
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Value of KPNA4 as a diagnostic and prognostic biomarker for hepatocellular carcinoma

Mingxing Xu, Hao Liang, Kun Li, Shu Zhu, Zhicheng Yao, Ruiyun Xu, Nan Lin,
https://doi.org/10.18632/aging.202447 pp 5263—5283
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Matrix stiffness promotes glioma cell stemness by activating BCL9L/Wnt/β-catenin signaling

Bei Tao, Yi Song, Yao Wu, Xiaobo Yang, Tangming Peng, Lilei Peng, Kaiguo Xia, Xiangguo Xia, Ligang Chen, Chuanhong Zhong,
https://doi.org/10.18632/aging.202449 pp 5284—5296
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LncRNA MIR205HG regulates melanomagenesis via the miR-299-3p/VEGFA axis

Jinlan Guo, Quan Gan, Caibin Gan, Xiaoning Zhang, Xinping Ma, Mingliang Dong,
https://doi.org/10.18632/aging.202450 pp 5297—5311
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Evaluation of the prognostic values of solute carrier (SLC) family 39 genes for patients with lung adenocarcinoma

Heng Zhou, Yaoqi Zhu, Huizhong Qi, Liang Liang, Hao Wu, Jingping Yuan, Qingyong Hu,
https://doi.org/10.18632/aging.202452 pp 5312—5331
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A novel risk model to predict first-ever ischemic stroke in heart failure with reduced ejection fraction

Xiaodong Zhou, Lingfang Yu, Weizhen Hu, Ruiyu Shi, Yinan Ji, Changzuan Zhou, Chenglong Xue, Guojia Yu, Weijian Huang, Peiren Shan,
https://doi.org/10.18632/aging.202458 pp 5332—5341
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Coumestrol mitigates retinal cell inflammation, apoptosis, and oxidative stress in a rat model of diabetic retinopathy via activation of SIRT1

Yanchao Xu, Yusong Zhang, Hongwei Liang, Xiaomeng Liu,
https://doi.org/10.18632/aging.202467 pp 5342—5357
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The lymphocyte-C-reactive protein ratio as the optimal inflammation-based score in patients with hepatocellular carcinoma underwent TACE

Liang-He Lu, Wei Wei, Shao-Hua Li, Yong-Fa Zhang, Rong-Ping Guo,
https://doi.org/10.18632/aging.202468 pp 5358—5368
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Inhibiting TLR4 signaling by linarin for preventing inflammatory response in osteoarthritis

Weihui Qi, Yanlin Chen, Shuaibo Sun, Xinxian Xu, Jingdi Zhan, Zijian Yan, Ping Shang, Xiaoyun Pan, Haixiao Liu,
https://doi.org/10.18632/aging.202469 pp 5369—5382
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CircMRE11A_013 binds to UBXN1 and integrates ATM activation enhancing lens epithelial cells senescence in age-related cataract

Junliang Liu, Jinling Zhang, Guowei Zhang, Tianqiu Zhou, Xi Zou, Huaijin Guan, Yong Wang,
https://doi.org/10.18632/aging.202470 pp 5383—5402
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RNF168 is highly expressed in esophageal squamous cell carcinoma and contributes to the malignant behaviors in association with the Wnt/β-catenin signaling pathway

Yunjiu Gou, Dacheng Jin, Shengliang He, Songchen Han, Qizhou Bai,
https://doi.org/10.18632/aging.202471 pp 5403—5414
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A retrospective study of long term follow-up of 2283 vitiligo patients treated by autologous, non-cultured melanocyte–keratinocyte transplantation

Dimin Zhang, Xiaodong Wei, Weisong Hong, Lifang Fu, Guopei Qian, Ai-e Xu,
https://doi.org/10.18632/aging.202472 pp 5415—5425
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Sequential tirofiban infusions combined with endovascular treatment may improve outcomes in acute ischemic stroke - a meta-analysis

Hongchen Zhao, Yiwei Feng, Xiaoming Rong, Yiting Mao, Zigao Wang, Yifeng Ling, Qiang Dong, Wenjie Cao,
https://doi.org/10.18632/aging.202473 pp 5426—5441
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Clinical and genomic characteristics of metabolic syndrome in colorectal cancer

Yanyan Li, Jungang Zhao, Xiaoli Wu, Yini Zhang, Yin Jin, Weiyang Cai,
https://doi.org/10.18632/aging.202474 pp 5442—5460
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Identification of prognostic immune-related genes in rhabdoid tumor of kidney based on TARGET database analysis

Huimou Chen, Suying Lu, Jinqiu Guan, Xiaoqin Zhu, Feifei Sun, Junting Huang, Jia Zhu, Juan Wang, Zijun Zhen, Yi Que, Xiaofei Sun, Yizhuo Zhang,
https://doi.org/10.18632/aging.202475 pp 5461—5474
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LncRNA PCGEM1 contributes to malignant behaviors of glioma by regulating miR-539-5p/CDK6 axis

Shu-Li Liu, Mao-Hua Chen, Xiao-Bo Wang, Rong-Kai You, Xue-Wei An, Qiu Zhao, Ren-Shu Wang,
https://doi.org/10.18632/aging.202476 pp 5475—5484
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Tumor microenvironment characterization in triple-negative breast cancer identifies prognostic gene signature

Yan Qin, Jiehua Deng, Lihua Zhang, Jiaxing Yuan, Huawei Yang, Qiuyun Li,
https://doi.org/10.18632/aging.202478 pp 5485—5505
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Comprehensive analysis of prognostic immune-related genes in the tumor microenvironment of colorectal cancer

Wei Li, Xiaojing Jin, Shang Guo, Fei Xu, Xingkai Su, Xia Jiang, Guiqi Wang,
https://doi.org/10.18632/aging.202479 pp 5506—5524
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QiShenYiQi pill activates autophagy to attenuate reactive myocardial fibrosis via the PI3K/AKT/mTOR pathway

Shichao Lv, Peng Yuan, Chunmiao Lu, Jianping Dong, Meng Li, Fan Qu, Yaping Zhu, Junping Zhang,
https://doi.org/10.18632/aging.202482 pp 5525—5538
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Development and validation of RNA binding protein-applied prediction model for gastric cancer

Shuang Dai, Yan Huang, Ting Liu, Zi-Han Xu, Tao Liu, Lan Chen, Zhi-Wu Wang, Feng Luo,
https://doi.org/10.18632/aging.202483 pp 5539—5552
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Melatonin protects against defects induced by Enniatin B1 during porcine early embryo development

Xiangyu Wang, Mingju Sun, Jingyu Li, Xuexiong Song, Hongbin He, Yanjun Huan,
https://doi.org/10.18632/aging.202484 pp 5553—5570
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The joint effect of energy reduction with calcium supplementation on the risk factors of type 2 diabetes in the overweight population: a two-year randomized controlled trial

Wei Wei, Wenbo Jiang, Wenbo Gu, Huanyu Wu, Haiyang Jiang, Guili Li, Qingrao Song, Jiaxin Huang, Xuanyang Wang, Lulu Wang, Changhao Sun, Tianshu Han, Ying Li,
https://doi.org/10.18632/aging.202485 pp 5571—5584
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TMEM106C contributes to the malignant characteristics and poor prognosis of hepatocellular carcinoma

Jicheng Duan, Youwen Qian, Xiaohui Fu, Meiling Chen, Kai Liu, Hu Liu, Jiahe Yang, Chen Liu, Yanxin Chang,
https://doi.org/10.18632/aging.202487 pp 5585—5606
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Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer

Jianwen Ye, Lei Qi, Zhicheng Du, Long Yu, Kunlun Chen, Renfeng Li, Ruo Feng, Wenlong Zhai,
https://doi.org/10.18632/aging.202488 pp 5607—5620
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Expression and prognostic values of ARID family members in breast cancer

Jinfeng Zhang, Siyu Hou, Zilong You, Guozheng Li, Shouping Xu, Xianyong Li, Xianyu Zhang, Bo Lei, Da Pang,
https://doi.org/10.18632/aging.202489 pp 5621—5637
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Long non-coding RNA TP73-AS1 is a potential immune related prognostic biomarker for glioma

Bo Zhang, Qinglin Li, Bin Wu, Shuyuan Zhang, Liwen Li, Kai Jin, Sheng Li, Kai Li, Zeng Wang, Yi Lu, Liang Xia, Caixing Sun,
https://doi.org/10.18632/aging.202490 pp 5638—5649
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Synergistic inflammatory signaling by cGAS may be involved in the development of atherosclerosis

Guan-Feng Lu, Sheng-Cai Chen, Yuan-Peng Xia, Zi-Ming Ye, Fei Cao, Bo Hu,
https://doi.org/10.18632/aging.202491 pp 5650—5673
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High expression of heme oxygenase-1 in tumor-associated macrophages characterizes a poor-prognosis subtype in nasopharyngeal carcinoma

Jianfeng Huang, Binbin Wan, Sha Li, Gang Liu, Qingfeng Pang, Jia Wu, Erwen Bao, Changling Sun, Yan Qin, Kewei Wang, Fei Yang, Yaxian Wu, Fuzheng Zhang, Bo Yang,
https://doi.org/10.18632/aging.202492 pp 5674—5685
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Identification of hub genes associated with adult acute myeloid leukemia progression through weighted gene co-expression network analysis

Ruiqi Zhu, Wenyi Lin, Liang Tang, Yu Hu,
https://doi.org/10.18632/aging.202493 pp 5686—5697
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Identification of novel candidate biomarkers for pancreatic adenocarcinoma based on TCGA cohort

Yang Jie, Wang Peng, Yuan-Yuan Li,
https://doi.org/10.18632/aging.202494 pp 5698—5717
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Comprehensive analysis of macrophage-related multigene signature in the tumor microenvironment of head and neck squamous cancer

Bo Lin, Hao Li, Tianwen Zhang, Xin Ye, Hongyu Yang, Yuehong Shen,
https://doi.org/10.18632/aging.202499 pp 5718—5747
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Global incidence and mortality of breast cancer: a trend analysis

Junjie Huang, Paul SF Chan, Veeleah Lok, Xiao Chen, Hanyue Ding, Yinzi Jin, Jinqiu Yuan, Xiang-qian Lao, Zhi-Jie Zheng, Martin CS Wong,
https://doi.org/10.18632/aging.202502 pp 5748—5803
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Macrophage migration inhibitory factor activates the inflammatory response in joint capsule fibroblasts following post-traumatic joint contracture

Yuxin Zhang, Shenji Lu, Shuai Fan, Lili Xu, Xin Jiang, Kexin Wang, Bin Cai,
https://doi.org/10.18632/aging.202505 pp 5804—5823
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Development and validation of an individual alternative splicing prognostic signature in gastric cancer

Shenghan Lou, Jian Zhang, Zhao Zhai, Xin Yin, Yimin Wang, Tianyi Fang, Yingwei Xue,
https://doi.org/10.18632/aging.202507 pp 5824—5844
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Down-regulation of estrogen-related receptor alpha (ERRα) inhibits gastric cancer cell migration and invasion in vitro and in vivo

Yuejiao Zhong, Kang He, Lin Shi, Lingxiang Chen, Bin Zhou, Rong Ma, Hui Yu, Jia Zhang, You Shuai, Yan Fei, Jianwei Lu,
https://doi.org/10.18632/aging.202508 pp 5845—5857
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GABARAP suppresses EMT and breast cancer progression via the AKT/mTOR signaling pathway

Ying Liu, Dandan Wang, Mengxia Lei, Jiayi Gao, Yuqing Cui, Xiaoying Jin, Qiujie Yu, Ying Jiang, Yan Guo, Yali Liu, Li Cai, Xuesong Chen,
https://doi.org/10.18632/aging.202510 pp 5858—5874
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Blockade of Indoleamine 2, 3-dioxygenase 1 ameliorates hippocampal neurogenesis and BOLD-fMRI signals in chronic stress precipitated depression

Lei Gao, Tingting Gao, Ting Zeng, Peng Huang, Nai-Kei Wong, Zhaoyang Dong, Yunjia Li, Guanghui Deng, Zhiyong Wu, Zhiping Lv,
https://doi.org/10.18632/aging.202511 pp 5875—5891
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Circ_ 0115744 acts as miR-144 sponge to promote and predict the metastasis of colorectal cancer

Xiaoming Ma, Long Lv, Chungen Xing,
https://doi.org/10.18632/aging.202513 pp 5892—5905
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Associations between TUBB-WWOX SNPs, their haplotypes, gene-gene, and gene-environment interactions and dyslipidemia

Chun-Xiao Liu, Rui-Xing Yin, Zong-Hu Shi, Peng-Fei Zheng, Guo-Xiong Deng, Yao-Zong Guan, Bi-Liu Wei,
https://doi.org/10.18632/aging.202514 pp 5906—5927
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Cell differentiation trajectory predicts patient potential immunotherapy response and prognosis in gastric cancer

Renshen Xiang, Yuping Rong, Yuhang Ge, Wei Song, Jun Ren, Tao Fu,
https://doi.org/10.18632/aging.202515 pp 5928—5945
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Multi-omics analysis identifies potential mechanisms of AURKB in mediating poor outcome of lung adenocarcinoma

Jie Huang, Qianyun Zhang, Juan Shen, Xueqin Chen, Shenglin Ma,
https://doi.org/10.18632/aging.202517 pp 5946—5966
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Transfer of lncRNA UCA1 by hUCMSCs-derived exosomes protects against hypoxia/reoxygenation injury through impairing miR-143-targeted degradation of Bcl-2

Liwei Diao, Qinghua Zhang,
https://doi.org/10.18632/aging.202520 pp 5967—5985
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Overexpression of hsa_circ_0002874 promotes resistance of non-small cell lung cancer to paclitaxel by modulating miR-1273f/MDM2/p53 pathway

Jianhao Xu, Liwei Ni, Fenglun Zhao, Xiaoxiao Dai, Jialong Tao, Jia Pan, Aiming Shi, Zhu Shen, Cunjin Su, Yusong Zhang,
https://doi.org/10.18632/aging.202521 pp 5986—6009
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Exosomal long non-coding RNA LINC00662 promotes non-small cell lung cancer progression by miR-320d/E2F1 axis

Xin Lv, Yingjie Lian, Zhanye Liu, Jianguang Xiao, Donghua Zhang, Xiaohua Yin,
https://doi.org/10.18632/aging.202522 pp 6010—6024
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SIRT6 enhances telomerase activity to protect against DNA damage and senescence in hypertrophic ligamentum flavum cells from lumbar spinal stenosis patients

Jianwei Chen, Zude Liu, Hantao Wang, Lie Qian, Zhanchun Li, Qingxin Song, Guibin Zhong,
https://doi.org/10.18632/aging.202536 pp 6025—6040
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Long non-coding RNA CERS6-AS1 facilitates the oncogenicity of pancreatic ductal adenocarcinoma by regulating the microRNA-15a-5p/FGFR1 axis

Zhennan Yun, Fanqi Meng, Shiquan Li, Ping Zhang,
https://doi.org/10.18632/aging.202540 pp 6041—6054
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miR-29b restrains cholangiocarcinoma progression by relieving DNMT3B-mediated repression of CDKN2B expression

Kun Cao, Bo Li, Ye-Wei Zhang, Hui Song, Yi-Gang Chen, Yong-Jun Gong, Hai-Yang Li, Shi Zuo,
https://doi.org/10.18632/aging.202549 pp 6055—6065
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Estimation of sarcopenia prevalence in individuals at different ages from Zheijang province in China

Jie Huang, Fan He, Xue Gu, Shoushun Chen, Zhendong Tong, Suya Zhong,
https://doi.org/10.18632/aging.202567 pp 6066—6075
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Hsa_circ_0038383-mediated competitive endogenous RNA network in recurrent implantation failure

Huishan Zhao, Lili Chen, Yinghua Shan, Gang Chen, Yongli Chu, Huangguan Dai, Xuemei Liu, Hongchu Bao,
https://doi.org/10.18632/aging.202590 pp 6076—6090
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Circ_0000527 promotes osteosarcoma cell progression through modulating miR-646/ARL2 axis

Xiangkun Wu, Lihua Yan, Yongxi Liu, Lilin Shang,
https://doi.org/10.18632/aging.202602 pp 6091—6102
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Functional analysis of brain derived neurotrophic factor (BDNF) in Huntington’s disease

Zhike Zhou, Shanshan Zhong, Rongwei Zhang, Kexin Kang, Xiaoqian Zhang, Ying Xu, Chuansheng Zhao, Mei Zhao,
https://doi.org/10.18632/aging.202603 pp 6103—6114
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Identification of miRNAs as diagnostic and prognostic markers in hepatocellular carcinoma

Hao Liang, Mingxing Xu, Zhiyong Xiong, Kunpeng Hu, Jiarui Yang, Mingbo Cao, Zhaozhong Zhong, Zhicheng Yao, Meihai Deng, Bo Liu,
https://doi.org/10.18632/aging.202606 pp 6115—6133
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P2Y12 receptor-mediated microglia activation involved in delayed encephalopathy after acute carbon monoxide poisoning

Wenping Xiang, Zhigang Yang, Hui Xue, Jingbo Wang, Fanyan Niu, Jie Wang, Chao Chen, Yaming Wang, Jiangxia Pang, Baojun Wang,
https://doi.org/10.18632/aging.202607 pp 6134—6143
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Effect of age and isolated systolic or diastolic hypertension on target organ damage in non-dialysis patients with chronic kidney disease

Yu Hao, Xue Li, Ye Zhu, Jianting Ke, Tanqi Lou, Man Li, Cheng Wang,
https://doi.org/10.18632/aging.202609 pp 6144—6155
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Extracellular vesicles from anoxia preconditioned mesenchymal stem cells alleviate myocardial ischemia/reperfusion injury

Chengyu Mao, Dongjiu Li, En Zhou, Erhe Gao, Tiantian Zhang, Shufang Sun, Lin Gao, Yuqi Fan, Changqian Wang,
https://doi.org/10.18632/aging.202611 pp 6156—6170
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Gene expression barcode values reveal a potential link between Parkinson’s disease and gastric cancer

Suyan Tian, Shishun Zhao, Mingbo Tang, Chi Wang,
https://doi.org/10.18632/aging.202623 pp 6171—6181
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Dexmedetomidine reverses MTX-induced neurotoxicity and inflammation in hippocampal HT22 cell lines via NCOA4-mediated ferritinophagy

Jingli Chen, Juan Wang, Chenxi Li, Huang Ding, Jishi Ye, Zhongyuan Xia,
https://doi.org/10.18632/aging.202626 pp 6182—6193
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USP30 protects against oxygen-glucose deprivation/reperfusion induced mitochondrial fragmentation and ubiquitination and degradation of MFN2

Chunli Chen, Haiyun Qin, Jiayu Tang, Zhiping Hu, Jieqiong Tan, Liuwang Zeng,
https://doi.org/10.18632/aging.202629 pp 6194—6204
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A history of cigarette smoking is associated with faster functional decline and reduction of entorhinal cortex volume in mild cognitive impairment

Mayun Chen, Chaoming Hu, Haoru Dong, Hanhan Yan, Peiliang Wu, Alzheimer’s Disease Neuroimaging Initiative,
https://doi.org/10.18632/aging.202646 pp 6205—6213
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Review

Early diagnosis of lung cancer: which is the optimal choice?

Jing Ning, Tao Ge, Minlin Jiang, Keyi Jia, Lei Wang, Wei Li, Bin Chen, Yu Liu, Hao Wang, Sha Zhao, Yayi He,
https://doi.org/10.18632/aging.202504 pp 6214—6227
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Correction

Correction for: circ5912 suppresses cancer progression via inducing MET in bladder cancer

Yinjie Su, Zehu Du, Guanglei Zhong, Yiyao Ya, B Junming, Juanyi Shi, Luping Chen, Wen Dong, Tianxin Lin,
https://doi.org/10.18632/aging.102886 pp 6228—6230
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