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Research Paper|Volume 13, Issue 4|pp 6066—6075

Estimation of sarcopenia prevalence in individuals at different ages from Zheijang province in China

Jie Huang1, Fan He2, Xue Gu2, Shoushun Chen3, Zhendong Tong4, Suya Zhong3
  • 1The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China
  • 2Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China
  • 3Putuo Mountain Community Center for Health and Service, Zhoushan, Zhejiang, China
  • 4Zhoushan Center for Disease Control and Prevention, Zhoushan, Zhejiang, China
* Equal contribution
Received: June 30, 2020Accepted: January 13, 2021Published: February 18, 2021
https://doi.org/10.18632/aging.202567

Copyright: © 2021 Huang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

In this study, we analyzed sarcopenia prevalence and the cut-off points for skeletal muscle mass index (SMI), gait speed, and handgrip strength in young (18-39 years), middle-aged (40-59 years), and elderly (>60 years) individuals (n=1685) from Zhejiang Province in China. The prevalence of sarcopenia among individuals above 65 years was 2.21%, 4.87%, 5.31%, 14.16%, and 16.37% according to five diagnostic criteria (AWGS2019, AWGS2014, EWGSOP1, EWGSOP2, and local standard). The mean SMI (Kg/m2) was 7.961±0.7966, 7.801±0.7276, and 7.544±0.7493, respectively, in young, middle-aged, and elderly males. The mean SMI in young, middle-aged, and elderly females was 6.1570±0.5658, 6.604±0.5658, and 6.248±0.7483, respectively. SMI correlated negatively with age (r=-0.2344, P<0.001), but was not associated with age in females (r=0.0573, P=0.1463). The cut-off point of SMI for sarcopenia was ≤6.3678 kg/m2 in males and ≤5.0254 kg/m2 in females. These findings shows that the prevalence of sarcopenia increased gradually with age and varied significantly based on the diagnostic criteria used for this analysis. The mean SMI of young women was lower than in middle-aged women, making them an unsuitable reference population for determining cut-off values for sarcopenia diagnosis.