This article has been corrected: The authors requested the replacement of Figure 1D, E, F, G, Figure 2I, Figure 3H and Table 1. The authors made changes to improve presentation of the panels. They removed duplications and overlaps of the images with minor modifications of the original data. The revised table reflects the updated properties of the patients sample pool.

These corrections do not change the content of the publication and do not affect the conclusion of this research. The authors apologize for the unintentional mistakes.

The corrected Figures and Table are provided below.

Lower circ5912 levels are associated with advanced bladder cancer. (D) Expression of circ5912 in 45 paired bladder cancer tissues; 58 bladder cancer tissues were evaluated and analyzed by: (E) stages, (F) tumor grade and (G) metastasis; (H) overall survival of 43 bladder cancer patients in following was analyzed based on the level of circ5912.

Figure 1. Lower circ5912 levels are associated with advanced bladder cancer. (D) Expression of circ5912 in 45 paired bladder cancer tissues; 58 bladder cancer tissues were evaluated and analyzed by: (E) stages, (F) tumor grade and (G) metastasis; (H) overall survival of 43 bladder cancer patients in following was analyzed based on the level of circ5912.

Silencing circ5912 promotes bladder cancer cell growth and metastasis in vitro. (I) migration and invasion were assessed by counting cells that were able to penetrate the trans-well membrane, scale bar: 25μm.

Figure 2. Silencing circ5912 promotes bladder cancer cell growth and metastasis in vitro. (I) migration and invasion were assessed by counting cells that were able to penetrate the trans-well membrane, scale bar: 25μm.

Overexpression of circ5912 suppresses bladder cancer growth and metastasis. (H) migration and invasion were assessed by counting cells that penetrated the trans-well membrane, scale bar: 25μm.

Figure 3. Overexpression of circ5912 suppresses bladder cancer growth and metastasis. (H) migration and invasion were assessed by counting cells that penetrated the trans-well membrane, scale bar: 25μm.

Table 1. Relationship between circ5912 level and clinical characteristics in bladder cancer.

TotalPatientsExpression of cic5912
HighLowp
Age(mean)5652.5259.480.200
Gender
Male4620260.052
Female1293
Tumor stage
Tis/Ta/T1282080.003
T221813
T3/T4918
Grade
High27621<0.001
Low31238
Number of tumors
Solitary4121200.773
Multiple1789
Lymph node metastasis
Negative261880.008
Positive321121
Follow-up (month, mean)38.46543.09534.0450.016