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• Research PaperVolume 13, Issue 17pp 20935-20961

  Hyperbaric oxygen therapy alleviates vascular dysfunction and amyloid burden in an Alzheimer’s disease mouse model and in elderly patients

  Relevance score: 0.00

  Ronit Shapira, Amos Gdalyahu, Irit Gottfried, Efrat Sasson, Amir Hadanny, Shai Efrati, Pablo Blinder, Uri Ashery

  Keywords: Alzheimer's disease, hyperbaric oxygen therapy, vascular dysfunction, cerebral blood flow, amyloid burden

  Published in Aging on September 9, 2021

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• Research PaperVolume 13, Issue 19pp 22710-22731

  Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model

  Relevance score: 0.00

  Gustavo Satoru Kajitani, Lear Brace, Jose Humberto Trevino-Villarreal, Kaspar Trocha, Michael Robert MacArthur, Sarah Vose, Dorathy Vargas, Roderick Bronson, Sarah Jayne Mitchell, Carlos Frederico Martins Menck, James Robert Mitchell

  Keywords: Cockayne syndrome, CSA, XPA, segmental progeria, inflammation, vascular dysfunction

  Published in Aging on October 10, 2021

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• Research PaperVolume 11, Issue 18pp 7620-7638

  Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice

  Relevance score: 0.00

  Huimin Li, Xinhui Wang, Xinyue Lu, Hongxin Zhu, Sheng Li, Shiwei Duan, Xinzhi Zhao, Fuquan Zhang, Gil Alterovitz, Fudi Wang, Qiang Li, Xiao-Li Tian, Mingqing Xu

  Keywords: co-expression network, hub gene, module, aging, vascular dysfunction, mouse

  Published in Aging on September 12, 2019

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• Research PaperVolume 15, Issue 23pp 13608-13627

  Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction

  Relevance score: 0.00

  Geum-Hwa Lee, Hwa-Young Lee, Young-Je Lim, Ji-Hyun Kim, Su-Jin Jung, Eun-Soo Jung, Soo-Wan Chae, Juwon Lee, Junghyun Lim, Mohammad Mamun Ur Rashid, Kyung Hyun Min, Han-Jung Chae

  Keywords: Angelica gigas, decursin, IRE1α sulfonation, RIDD, SIRT1, vascular dysfunction

  Published in Aging on December 13, 2023

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• Research PaperVolume 17, Issue 11pp 2717-2743

  Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence

  Relevance score: 0.00

  Parminder Singh, Ravinandan Venkatasubramanian, Sophia A. Mahoney, Mary A. Darrah, Katelyn R. Ludwig, Alice Zhang, Kiyomi Kaneshiro, Lizbeth Enriquez Najera, Lauren Wimer, Muniesh M. Shanmugam, Edgard Morazan, James J. Galligan, Marrisa N. Trujillo, Richmond Sarpong, Douglas R. Seals, Pankaj Kapahi, Zachary S. Clayton

  Keywords: glycation stress, methylglyoxal, pulse wave velocity, gly-low, vascular dysfunction

  Published in Aging on November 14, 2025

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• EditorialVolume 11, Issue 2pp 299-300

  Endothelial stiffening in dyslipidemia

  Relevance score: 0.00

  Elizabeth Le Master, Irena Levitan

  Keywords: endothelial stiffness, oxLDL, CD36, vascular dysfunction

  Published in Aging on January 22, 2019

• Research PaperVolume 8, Issue 5pp 1064-1078

  SIRT6 protects against endothelial dysfunction and atherosclerosis in mice

  Relevance score: 0.00

  Suowen Xu, Meimei Yin, Marina Koroleva, Michael A. A. Mastrangelo, Wenbo Zhang, Peter Bai, Peter J. J. Little, Zheng Gen Gen Jin

  Keywords: atherosclerosis, endothelial dysfunction, SIRT6, vascular inflammation, RNA-seq

  Published in Aging on May 30, 2016

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• Research PaperVolume 17, Issue 4pp 885-907

  Fisetin ameliorates vascular smooth muscle cell calcification via DUSP1-dependent p38 MAPK inhibition

  Relevance score: 0.00

  Mehdi Razazian, Sheyda Bahiraii, Azmat Sohail, Markus Mandl, Isratul Jannat, Georg Beilhack, Ioana Alesutan, Jakob Voelkl

  Keywords: vascular calcification, vascular smooth muscle cells, fisetin, dual-specificity phosphatase 1, p38 MAPK

  Published in Aging on April 2, 2025

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• Research PaperVolume 17, Issue 2pp 448-463

  Chronic β3 adrenergic agonist treatment improves neurovascular coupling responses, attenuates blood-brain barrier leakage and neuroinflammation, and enhances cognition in aged mice

  Relevance score: 0.00

  Duraipandy Natarajan, Shoba Ekambaram, Stefano Tarantini, Raghavendra Y. Nagaraja, Andriy Yabluchanskiy, Andria F. Hedrick, Vibhudutta Awasthi, Madhan Subramanian, Anna Csiszar, Priya Balasubramanian

  Keywords: vascular cognitive impairment, endothelial function, glucose uptake, beta 3 adrenergic receptor agonist, blood-brain barrier leakage

  Published in Aging on February 19, 2025

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• Research PaperVolume 16, Issue 11pp 9369-9385

  Identification of key genes and biological pathways associated with vascular aging in diabetes based on bioinformatics and machine learning

  Relevance score: 0.00

  Sha Wang, Xia Wang, Jing Chen, Min Wang, Chi Zhang

  Keywords: diabetes, cardiovascular disease, vascular aging, vascular smooth muscle cell (VSMC), bioinformatics, machine learning

  Published in Aging on May 27, 2024

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• Research PaperVolume 16, Issue 6pp 5065-5076

  The protective effects of Irbesartan in cognitive impairment in hypertension

  Relevance score: 0.00

  Shengyun Hao, Qian He, Yuan Yuan, Qiong Mu

  Keywords: vascular cognitive impairment (VCI), Irbesartan, hypertension, cognitive impairment, cAMP/CREB

  Published in Aging on March 23, 2024

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• Research PaperVolume 16, Issue 5pp 4363-4377

  Probucol protects against brain damage caused by intra-neural pyroptosis in rats with vascular dementia through inhibition of the Syk/Ros pathway

  Relevance score: 0.00

  Jingyi Zhu, Jing Du, Wenhui Kou, Chenling Liu, Jianchun Fan, Ziyan Zhu, Lexiu Deng, Lingling Guan, Yuandi Wang, Aimei Yu

  Keywords: vascular dementia, pyroptosis, probucol, spleen tyrosine kinase, oxidative stress

  Published in Aging on February 23, 2024

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• Research PaperVolume 16, Issue 3pp 2438-2456

  Interaction of Sp1 and Setd8 promotes vascular smooth muscle cells apoptosis by activating Mark4 in vascular calcification

  Relevance score: 0.00

  Yun Li, Meijuan Cheng, Jingjing Jin, Dongxue Zhang, Shenglei Zhang, Yaling Bai, Jinsheng Xu

  Keywords: vascular calcification, apoptosis, Mark4, Sp1, Setd8

  Published in Aging on February 1, 2024

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• Research PaperVolume 15, Issue 21pp 12264-12274

  Influences and mechanism of erythropoietin on the cognitive function of vascular dementia rats

  Relevance score: 0.00

  Zhipeng Tang, Xiuqin Li, Nan Yin, Ming Zhao, Qingchuan Hu, Peiyuan Lv

  Keywords: vascular dementia, erythropoietin, oxidative stress, cell apoptosis

  Published in Aging on November 6, 2023

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• Research PaperVolume 15, Issue 1pp 70-91

  Histone methyltransferase Smyd2 drives vascular aging by its enhancer-dependent activity

  Relevance score: 0.00

  Zhenghua Su, Haibi Su, Jie Xu, Gang Wei, Lefeng Qu, Ting Ni, Di Yang, Yizhun Zhu

  Keywords: vascular aging, Smyd2, H3K4me1, enhancer-dependent activity

  Published in Aging on December 28, 2022

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• Research PaperVolume 15, Issue 4pp 982-1003

  Identification of cellular heterogeneity and key signaling pathways associated with vascular remodeling and calcification in young and old primate aortas based on single-cell analysis

  Relevance score: 0.00

  Yehu Yin, Congcong Huang, Zidi Wang, Pan Huang, Shanshan Qin

  Keywords: vascular aging, scRNA-seq, cellular heterogeneity, cell-cell communication, EGF

  Published in Aging on December 23, 2022

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• Research PaperVolume 14, Issue 9pp 3910-3920

  Vascular function in the aging human brain during muscle exertion

  Relevance score: 0.00

  Maijian Zhu, Tania Xu Yar Lee, Yu-Wen Hsieh, Li-Fan Lai, Giancarlo Condello, Cyril J. Donnelly, Marc Smith, Sareena Hanim Hamzah, Boon-Hooi Lim, Chih-Yang Huang, Nai-Fang Chi, Chia-Hua Kuo

  Keywords: frailty, vascular function, muscle strength, endothelial function, NIRS

  Published in Aging on May 2, 2022

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• Research PaperVolume 13, Issue 11pp 14651-14674

  Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

  Relevance score: 0.00

  Sang-Ha Baik, Sharmelee Selvaraji, David Y. Fann, Luting Poh, Dong-Gyu Jo, Deron R. Herr, Shenpeng R. Zhang, Hyun Ah Kim, Michael De Silva, Mitchell K.P. Lai, Christopher Li-Hsian Chen, Grant R. Drummond, Kah-Leong Lim, Christopher G. Sobey, Thiruma V. Arumugam

  Keywords: aging, vascular dementia, transcriptome, chronic cerebral hypoperfusion, brain

  Published in Aging on June 1, 2021

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• Research PaperVolume 13, Issue 10pp 14001-14014

  Adalimumab ameliorates memory impairments and neuroinflammation in chronic cerebral hypoperfusion rats

  Relevance score: 0.00

  Jing-Jing Xu, Si Guo, Rui Xue, Lin Xiao, Jun-Na Kou, Yu-Qiong Liu, Jun-Ya Han, Jing-Jie Fu, Na Wei

  Keywords: adalimumab, vascular dementia, neuroinflammation

  Published in Aging on May 24, 2021

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• Research PaperVolume 13, Issue 7pp 9542-9565

  Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca²⁺/CaMKII signal pathway

  Relevance score: 0.00

  Ting-Ting Chen, Xue Zhou, Yi-Ni Xu, Yue Li, Xiao-Ying Wu, Quan Xiang, Ling-Yun Fu, Xiao-Xia Hu, Ling Tao, Xiang-Chun Shen

  Keywords: gastrodin, vascular dementia, autophagic flux, Ca²⁺, CaMKII

  Published in Aging on March 10, 2021

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