Online ISSN: 1945-4589
The cover for issue 5 of Aging features Figure 2A, 'Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan' from Patrick et al.

Volume 8, Issue 5

May 2016
pp 833—1158

About the Cover

The cover for issue 5 of Aging features Figure 2A, 'Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan' from Patrick et al.

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Editorials

Rapamycin slows down gut aging

Uma Gaur, Xiaolan Fan, Mingyao Yang,
https://doi.org/10.18632/aging.100963 pp 833—834
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Cancer comes of age embryonically

Vi K. Chiu, Anne-France Le Rolle,
https://doi.org/10.18632/aging.100959 pp 835—836
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SHIP prevents metastasis

Gerald Krystal, Melisa J Hamilton, Kevin L Bennewith,
https://doi.org/10.18632/aging.100964 pp 837—838
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Microbes and healthful longevity

Susan E. Erdman,
https://doi.org/10.18632/aging.100969 pp 839—840
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Research Papers

Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan

Alison Patrick, Michael Seluanov, Chaewon Hwang, Jonathan Tam, Tanya Khan, Ari Morgenstern, Lauren Wiener, Juan M. M. Vazquez, Hiba Zafar, Robert Wen, Malika Muratkalyeva, Katherine Doerig, Maria Zagorulya, Lauren Cole, Sophia Catalano, Aliny AB AB Lobo Ladd, A. Augusto Augusto Coppi, Yüksel Coşkun, Xiao Tian, Julia Ablaeva, Eviatar Nevo, Vadim N. N. Gladyshev, Zhengdong D. D. Zhang, Jan Vijg, Andrei Seluanov, Vera Gorbunova,
https://doi.org/10.18632/aging.100958 pp 841—847
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Aging of immune system: immune signature from peripheral blood lymphocyte subsets in 1068 healthy adults

Ling Qin, Xie Jing, Zhifeng Qiu, Wei Cao, Yang Jiao, Jean-Pierre Routy, Taisheng Li,
https://doi.org/10.18632/aging.100894 pp 848—859
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Exercise: a “new drug” for elderly patients with chronic heart failure

Roberto Antonicelli, Liana Spazzafumo, Simonetta Scalvini, Fabiola Olivieri, Maria Vittoria Matassini, Gianfranco Parati, Donatella Del Sindaco, Raffaella Gallo, Fabrizia Lattanzio,
https://doi.org/10.18632/aging.100901 pp 860—872
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Mutual inhibition of insulin signaling and PHLPP-1 determines cardioprotective efficiency of Akt in aged heart

Yuan Xing, Wanqing Sun, Yishi Wang, Feng Gao, Heng Ma,
https://doi.org/10.18632/aging.100933 pp 873—887
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Autofluorescence as a measure of senescence in C. elegans: look to red, not blue or green

Zachary Pincus, Travis C Mazer, Frank J Slack,
https://doi.org/10.18632/aging.100936 pp 889—898
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Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet

Michel Bernier, Devin Wahl, Ahmed Ali, Joanne Allard, Shakeela Faulkner, Artur Wnorowski, Mitesh Sanghvi, Ruin Moaddel, Irene Alfaras, Julie A. Mattison, Stefano Tarantini, Zsuzsanna Tucsek, Zoltan Ungvari, Anna Csiszar, Kevin J. Pearson, Rafael de Cabo,
https://doi.org/10.18632/aging.100942 pp 899—916
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The effects of graded levels of calorie restriction: VII. Topological rearrangement of hypothalamic aging networks

Davina Derous, Sharon E Mitchell, Cara L Green, Yingchun Wang, Jing Dong J Han, Luonan Chen, Daniel E.L Promislow, David Lusseau, John R Speakman, Alex Douglas,
https://doi.org/10.18632/aging.100944 pp 917—931
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MMP-9 overexpression is associated with intragenic hypermethylation of MMP9 gene in melanoma

Luca Falzone, Rossella Salemi, Salvatore Travali, Aurora Scalisi, James A. A. McCubrey, Saverio Candido, Massimo Libra,
https://doi.org/10.18632/aging.100951 pp 933—940
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Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells

Sandy S.C Hung, Nicole J Van Bergen, Stacey Jackson, Helena Liang, David A. A Mackey, Damián Hernández, Shiang Y Lim, Alex W Hewitt, Ian Trounce, Alice Pébay, Raymond C.B Wong,
https://doi.org/10.18632/aging.100950 pp 945—957
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Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer

Ilenia Segatto, Samuele Massarut, Robert Boyle, Gustavo Baldassarre, David Walker, Barbara Belletti,
https://doi.org/10.18632/aging.100954 pp 958—973
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Defects in MAP1S-mediated autophagy turnover of fibronectin cause renal fibrosis

Guibin Xu, Fei Yue, Hai Huang, Yongzhong He, Xun Li, Haibo Zhao, Zhengming Su, Xianhan Jiang, Wenjiao Li, Jing Zou, Qi Chen, Leyuan Liu,
https://doi.org/10.18632/aging.100957 pp 977—985
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Inverse correlation between longevity and developmental rate among wild C. elegans strains

Yujin Lee, Wooseon Hwang, Juyoung Jung, Sangsoon Park, Josephine Jill T. Cabatbat, Pan-Jun Kim, Seung-Jae V Lee,
https://doi.org/10.18632/aging.100960 pp 986—994
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Metabolic drift in the aging brain

Julijana Ivanisevic, Kelly L Stauch, Michael Petrascheck, H Paul Benton, Adrian A Epstein, Mingliang Fang, Santhi Gorantla, Minerva Tran, Linh Hoang, Michael E Kurczy, Michael D Boska, Howard E Gendelman, Howard S Fox, Gary Siuzdak,
https://doi.org/10.18632/aging.100961 pp 1000—1020
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Deep biomarkers of human aging: Application of deep neural networks to biomarker development

Evgeny Putin, Polina Mamoshina, Alexander Aliper, Mikhail Korzinkin, Alexey Moskalev, Alexey Kolosov, Alexander Ostrovskiy, Charles Cantor, Jan Vijg, Alex Zhavoronkov,
https://doi.org/10.18632/aging.100968 pp 1021—1030
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Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures

Monika Eipel, Felix Mayer, Tanja Arent, Marcelo R. P. R.P. Ferreira, Carina Birkhofer, Uwe Gerstenmaier, Ivan G. G. Costa, Stefanie Ritz-Timme, Wolfgang Wagner,
https://doi.org/10.18632/aging.100972 pp 1034—1044
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Ischemic stroke induces gut permeability and enhances bacterial translocation leading to sepsis in aged mice

Joshua Crapser, Rodney Ritzel, Rajkumar Verma, Venugopal R. R. Venna, Fudong Liu, Anjali Chauhan, Edward Koellhoffer, Anita Patel, Austin Ricker, Kendra Maas, Joerg Graf, Louise D. D. McCullough,
https://doi.org/10.18632/aging.100952 pp 1049—1060
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SIRT6 protects against endothelial dysfunction and atherosclerosis in mice

Suowen Xu, Meimei Yin, Marina Koroleva, Michael A. A. Mastrangelo, Wenbo Zhang, Peter Bai, Peter J. J. Little, Zheng Gen Gen Jin,
https://doi.org/10.18632/aging.100975 pp 1064—1078
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Lack of collagen VI promotes neurodegeneration by impairing autophagy and inducing apoptosis during aging

Matilde Cescon, Peiwen Chen, Silvia Castagnaro, Ilaria Gregorio, Paolo Bonaldo,
https://doi.org/10.18632/aging.100924 pp 1083—1098
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Rapamycin reverses the senescent phenotype and improves immuno-regulation of mesenchymal stem cells from MRL/lpr mice and systemic lupus erythematosus patients through inhibition of the mTOR signaling pathway

Zhifeng Gu, Wei Tan, Juan Ji, Guijian Feng, Yan Meng, Zhanyun Da, Genkai Guo, Yunfei Xia, Xinhang Zhu, Guixiu Shi, Chun Cheng,
https://doi.org/10.18632/aging.100925 pp 1102—1114
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Transgenerational programming of longevity and reproduction by post-eclosion dietary manipulation in Drosophila

Brian Xia, Steven de Belle,
https://doi.org/10.18632/aging.100932 pp 1115—1134
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Accelerated ageing and renal dysfunction links lower socioeconomic status and dietary phosphate intake

Ruth McClelland, Kelly Christensen, Suhaib Mohammed, Dagmara McGuinness, Josephine Cooney, Andisheh Bakshi, Evangelia Demou, Ewan MacDonald, Muriel Caslake, Peter Stenvinkel, Paul G. G. Shiels,
https://doi.org/10.18632/aging.100948 pp 1135—1148
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Letters to the Editor

Bonnie and Clyde: Vitamin C and iron are partners in crime in iron deficiency anaemia and its potential role in the elderly

Darius J.R Lane, Patric J Jansson, Des R Richardson,
https://doi.org/10.18632/aging.100966 pp 1150—1152
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Mir 145/143: tumor suppressor, oncogenic microenvironmental factor or ...both?

Mario Cioce, Sabrina Strano, Paola Muti, Giovanni Blandino,
https://doi.org/10.18632/aging.100965 pp 1153—1155
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Errata

Erratum: Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles

Sylvia Weilner, Verena Keider, Melanie Winter, Eva Harreither, Benjamin Salzer, Florian Weiss, Elisabeth Schraml, Paul Messner, Peter Pietschmann, Florian Hildner, Christian Gabriel, Heinz Redl, Regina Grillari-Voglauer, Johannes Grillari,
https://doi.org/10.18632/aging.100917 pp 1156—1157
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Erratum: Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid

Yuanyuan Li, Xing Yuan, Yunheng Shen, Jing Zhao, Rongcai Yue, Fang Liu, Weiwei He, Rui Wang, Lei Shan, Weidong Zhang,
https://doi.org/10.18632/aging.100956 pp 1158
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