Volume 8, Issue 6

June 2016pp 1159—1286

About the Cover

The cover for issue 6 of Aging features Figure 6B, 'Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues' from Hisamatsu et al.

Editorials

Targeting mutant p53 for cancer therapy

Moshe Oren, Perry Tal, Varda Rotter

https://doi.org/10.18632/aging.100992pp 1159—1160

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Zinc intake, microRNA dysregulation, and esophageal cancer

Louise Y. Fong, John L. Farber, Carlo M. Croce

https://doi.org/10.18632/aging.100978pp 1161—1162

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Aging: T cell metabolism within tumors

Ying Zhang, Hildegund CJ Ertl

https://doi.org/10.18632/aging.100979pp 1163—1164

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mTORC1 regulates nutrient access in Ras-mediated tumors

Heesun Cheong

https://doi.org/10.18632/aging.100974pp 1165—1166

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Research Papers

Oral trehalose supplementation improves resistance artery endothelial function in healthy middle-aged and older adults

Rachelle E. Kaplon, Sierra D. Hill, Nina Z. Bispham, Jessica R. Santos-Parker, Molly J. Nowlan, Laura L. Snyder, Michel Chonchol, Thomas J. LaRocca, Matthew B. McQueen, Douglas R. Seals

https://doi.org/10.18632/aging.100962pp 1167—1183

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Reduced SOD2 expression is associated with mortality of hepatocellular carcinoma patients in a mutant p53-dependent manner

Ren Wang, Chen Yin, Xiao-Xing Li, Xian-Zi Yang, Yang Yang, Mei-Yin Zhang, Hui-Yun Wang, X.F. Steven Steven Zheng

https://doi.org/10.18632/aging.100967pp 1184—1197

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Fat-specific Dicer deficiency accelerates aging and mitigates several effects of dietary restriction in mice

Felipe C. G. C. Reis, Jéssica L. O. L. Branquinho, Bruna B. B. Brandão, Beatriz A. A. Guerra, Ismael D. D. Silva, Andrea Frontini, Thomas Thomou, Loris Sartini, Saverio Cinti, C. Ronald Ronald Kahn, William T. T. Festuccia, Alicia J. J. Kowaltowski, Marcelo A. A. Mori

https://doi.org/10.18632/aging.100970pp 1201—1215

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Retinoic acid treated human dendritic cells induce T regulatory cells via the expression of CD141 and GARP which is impaired with age

Sudhanshu Agrawal, Sreerupa Ganguly, Alexander Tran, Padmaja Sundaram, Anshu Agrawal

https://doi.org/10.18632/aging.100973pp 1223—1235

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Overexpressed HDAC4 is associated with poor survival and promotes tumor progression in esophageal carcinoma

Li-Si Zeng, Xian-Zi Yang, Yue-Feng Wen, Shi-Juan Mai, Meng-He Wang, Mei-Yin Zhang, X.F. Steven Zheng, Hui-Yun Wang

https://doi.org/10.18632/aging.100980pp 1236—1248

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Reversal of cognitive decline in Alzheimer's disease

Dale E. E. Bredesen, Edwin C. C. Amos, Jonathan Canick, Mary Ackerley, Cyrus Raji, Milan Fiala, Jamila Ahdidan

https://doi.org/10.18632/aging.100981pp 1250—1258

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Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues

Daisuke Hisamatsu, Michiko Ohno-Oishi, Shiho Nakamura, Yo Mabuchi, Hayato Naka-Kaneda

https://doi.org/10.18632/aging.100982pp 1259—1269

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ERP44 inhibits human lung cancer cell migration mainly via IP3R2

Xue Huang, Meng Jin, Ying-Xiao Chen, Jun Wang, Kui Zhai, Yan Chang, Qi Yuan, Kai-Tai Yao, Guangju Ji

https://doi.org/10.18632/aging.100984pp 1276—1285

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