Volume 8, Issue 7

July 2016
pp 1287—1571

About the Cover

The cover for issue 7 of Aging features Figure S4, 'Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells' from Hall et al.

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Table of Contents

Editorials

Mitochondria in aging cell differentiation

Zdena Palková, Libuše Váchová,

https://doi.org/10.18632/aging.100993 pp 1287—1288

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Repurposing Tecfidera for cancer

Laurence Booth, Mark Malkin, Paul Dent,

https://doi.org/10.18632/aging.101001 pp 1289—1290

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The Na⁺/H⁺ exchanger in metastasis

Schammim Ray Amith, Larry Fliegel,

https://doi.org/10.18632/aging.101002 pp 1291

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Lymphoid malignancies ARNT unstoppable

Kacie A. Gardella, Richa Tiwary, Casey W. Wright,

https://doi.org/10.18632/aging.101010 pp 1292—1293

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Research Papers

Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells

Brandon M. Hall, Vitaly Balan, Anatoli S. Gleiberman, Evguenia Strom, Peter Krasnov, Lauren P. Virtuoso, Elena Rydkina, Slavoljub Vujcic, Karina Balan, Ilya Gitlin, Katerina Leonova, Alexander Polinsky, Olga B. Chernova, Andrei V. Gudkov,

https://doi.org/10.18632/aging.100991 pp 1294—1315

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Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses

Servet Özcan, Nicola Alessio, Mustafa B. B. Acar, Eda Mert, Fatih Omerli, Gianfranco Peluso, Umberto Galderisi,

https://doi.org/10.18632/aging.100971 pp 1316—1327

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Mitophagy-driven mitochondrial rejuvenation regulates stem cell fate

Alejandro Vazquez-Martin, Chris Van Van den Haute, Sílvia Cufí, Bruna Corominas Corominas-Faja, Elisabet Cuyàs, Eugeni Lopez-Bonet, Esther Rodriguez-Gallego, Salvador Fernández-Arroyo, Jorge Joven, Veerle Baekelandt, Javier A. A. Menendez,

https://doi.org/10.18632/aging.100976 pp 1330—1349

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Telomerase and estrogen-sensing activities are essential for continued mammary growth in vivo but dispensable for “reprogramming” neural stem cells

Andrea L. L. George, Corinne A. A. Boulanger, Gilbert H. H. Smith,

https://doi.org/10.18632/aging.100985 pp 1353—1362

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Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study

Jacob J.E. J.E. Koopman, Jeroen Pijpe, Stefan Böhringer, David van van Bodegom, Ulrika K. K. Eriksson, Hernando Sanchez-Faddeev, Juventus B. B. Ziem, Bas Zwaan, P. Eline Eline Slagboom, Peter de de Knijff, Rudi G.J. G.J. Westendorp,

https://doi.org/10.18632/aging.100986 pp 1364—1374

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FOXM1 regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells

Artem Smirnov, Emanuele Panatta, AnnaMaria Lena, Daniele Castiglia, Nicola Di Daniele, Gerry Melino, Eleonora Candi,

https://doi.org/10.18632/aging.100988 pp 1384—1397

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Longitudinal decline of leukocyte telomere length in old age and the association with sex and genetic risk

Kari Berglund, Chandra A. Reynolds, Alexander Ploner, Lotte Gerritsen, Iiris Hovatta, Nancy L. Pedersen, Sara Hägg,

https://doi.org/10.18632/aging.100995 pp 1398—1415

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Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans

Simin N. Meydani, Sai K. Das, Carl F. Pieper, Michael R. Lewis, Sam Klein, Vishwa D. Dixit, Alok K. Gupta, Dennis T. Villareal, Manjushri Bhapkar, Megan Huang, Paul J. Fuss, Susan B. Roberts, John O. Holloszy, Luigi Fontana,

https://doi.org/10.18632/aging.100994 pp 1416—1431

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Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones

Louise D. McCullough, Mehwish A. Mirza, Yan Xu, Kathryn Bentivegna, Eleanor B. Steffens, Rodney Ritzel, Fudong Liu,

https://doi.org/10.18632/aging.100997 pp 1432—1441

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miR-638 suppresses DNA damage repair by targeting SMC1A expression in terminally differentiated cells

Mingyang He, Yi Lin, Yunlan Tang, Yi Liu, Weiwei Zhou, Chuang Li, Guihong Sun, Mingxiong Guo,

https://doi.org/10.18632/aging.100998 pp 1442—1456

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Skin aging: are adipocytes the next target?

Ilja L. Kruglikov, Philipp E. Scherer,

https://doi.org/10.18632/aging.100999 pp 1457—1469

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Caloric restriction stimulates autophagy in rat cortical neurons through neuropeptide Y and ghrelin receptors activation

Marisa Ferreira-Marques, Célia A. Aveleira, Sara Carmo-Silva, Mariana Botelho, Luís Pereira de Almeida, Cláudia Cavadas,

https://doi.org/10.18632/aging.100996 pp 1470—1484

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Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels

Steve Horvath, Peter Langfelder, Seung Kwak, Jeff Aaronson, Jim Rosinski, Thomas F. Vogt, Marika Eszes, Richard L.M. Faull, Maurice A. Curtis, Henry J. Waldvogel, Oi-Wa Choi, Spencer Tung, Harry V. Vinters, Giovanni Coppola, X. William Yang,

https://doi.org/10.18632/aging.101005 pp 1485—1512

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Dietary and microbiome factors determine longevity in Caenorhabditis elegans

Adolfo Sánchez-Blanco, Alberto Rodríguez-Matellán, Ana González-Paramás, Susana González-Manzano, Stuart K. Kim, Faustino Mollinedo,

https://doi.org/10.18632/aging.101008 pp 1513—1539

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Cyclin A2 promotes DNA repair in the brain during both development and aging

Patrick E. Gygli, Joshua C. Chang, Hamza N. Gokozan, Fay P. Catacutan, Theresa A. Schmidt, Behiye Kaya, Mustafa Goksel, Faisal S. Baig, Shannon Chen, Amelie Griveau, Wojciech Michowski, Michael Wong, Kamalakannan Palanichamy, Piotr Sicinski, Randy J. Nelson, Catherine Czeisler, José J. Otero,

https://doi.org/10.18632/aging.100990 pp 1540—1570

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Erratum

Erratum: Mitochondrial Hormesis links nutrient restriction to improved metabolism in fat cell

Daniele Lettieri Barbato, Giuseppe Tatulli, Katia Aquilano, Maria R. Ciriolo,

https://doi.org/10.18632/aging.101003 pp 1571

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