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Volume 8, Issue 8

August 2016pp 1572—1829

About the Cover

The cover for issue 8 of Aging features Figure 6, 'A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts' from Kabir et al.

HER2-positive feline mammary carcinoma

Cláudia Marques, Jorge Correia, Fernando Ferreira

https://doi.org/10.18632/aging.101015pp 1574—1575
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Research Perspective

Fish oil supplements, longevity and aging

João Pedro de Magalhães, Michael Müller, G. Ed. Rainger, Wilma Steegenga

https://doi.org/10.18632/aging.101021pp 1578—1582
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Priority Research Paper

Impact of biological aging on arterial aging in American Indians: findings from the Strong Heart Family Study

Hao Peng, Yun Zhu, Fawn Yeh, Shelley A. Cole, Lyle G. Best, Jue Lin, Elizabeth Blackburn, Richard B. Devereux, Mary J. Roman, Elisa T. Lee, Barbara V. Howard, Jinying Zhao

https://doi.org/10.18632/aging.101013pp 1583—1592
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Research Papers

Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)

Marco Fiorillo, Rebecca Lamb, Herbert B. B. Tanowitz, Anna Rita Rita Cappello, Ubaldo E. E. Martinez-Outschoorn, Federica Sotgia, Michael P. P. Lisanti

https://doi.org/10.18632/aging.100983pp 1593—1606
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A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts

Tasnuva D. D. Kabir, Ross J. J. Leigh, Hataitip Tasena, Massimiliano Mellone, Ricardo D. D. Coletta, Eric K. K. Parkinson, Stephen S. S. Prime, Gareth J. J. Thomas, Ian C. C. Paterson, Donghui Zhou, John McCall, Paul M. M. Speight, Daniel W. W. Lambert

https://doi.org/10.18632/aging.100987pp 1608—1624
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Ionizing radiation-mediated premature senescence and paracrine interactions with cancer cells enhance the expression of syndecan 1 in human breast stromal fibroblasts: the role of TGF-β

Eleni Liakou, Eleni Mavrogonatou, Harris Pratsinis, Sophia Rizou, Konstantinos Evangelou, Petros N. Panagiotou, Nikos K. Karamanos, Vassilis G. Gorgoulis, Dimitris Kletsas

https://doi.org/10.18632/aging.100989pp 1650—1669
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BMI1 inhibits senescence and enhances the immunomodulatory properties of human mesenchymal stem cells via the direct suppression of MKP-1/DUSP1

Jin Young Lee, Kyung-Rok Yu, Hyung-Sik Kim, Insung Kang, Jae-Jun Kim, Byung-Chul Lee, Soon Won Choi, Ji-Hee Shin, Yoojin Seo, Kyung-Sun Kang

https://doi.org/10.18632/aging.101000pp 1670—1689
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Loss of oxidative defense and potential blockade of satellite cell maturation in the skeletal muscle of patients with cancer but not in the healthy elderly

Joanna Brzeszczyńska, Neil Johns, Alain Schilb, Simone Degen, Martin Degen, Ramon Langen, Annemie Schols, David J Glass, Ronenn Roubenoff, Carolyn A. Greig, Carsten Jacobi, Kenneth CH. Fearon, James A. Ross

https://doi.org/10.18632/aging.101006pp 1690—1702
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Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes

Julia Platas, Maria Isabel Guillén, Maria Dolores Pérez del Caz, Francisco Gomar, Miguel Angel Castejón, Vicente Mirabet, Maria José Alcaraz

https://doi.org/10.18632/aging.101007pp 1703—1717
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Biological and biophysics aspects of metformin-induced effects: cortex mitochondrial dysfunction and promotion of toxic amyloid pre-fibrillar aggregates

Pasquale Picone, Silvia Vilasi, Fabio Librizzi, Marco Contardi, Domenico Nuzzo, Luca Caruana, Sara Baldassano, Antonella Amato, Flavia Mulè, Pier Luigi San Biagio, Daniela Giacomazza, Marta Di Carlo

https://doi.org/10.18632/aging.101004pp 1718—1734
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Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7

Thuy T. Nguyen, Samuel W. Caito, William E. Zackert, James D. West, Shijun Zhu, Michael Aschner, Joshua P. Fessel, L. Jackson Roberts II

https://doi.org/10.18632/aging.101011pp 1759—1780
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Duplication of the mitochondrial control region is associated with increased longevity in birds

Ilze Skujina, Robert McMahon, Vasileios Panagiotis E. Lenis, Georgios V. Gkoutos, Matthew Hegarty

https://doi.org/10.18632/aging.101012pp 1781—1789
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Assessment of the contribution of APOE gene variants to metabolic phenotypes associated with familial longevity at middle age

Raymond Noordam, Charlotte H. Oudt, Joris Deelen, P. Eline Slagboom, Marian Beekman, Diana van Heemst

https://doi.org/10.18632/aging.101017pp 1790—1801
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Aging: a portrait from gene expression profile in blood cells

Elisa Calabria, Emilia Maria Cristina Mazza, Kenneth Allen Dyar, Silvia Pogliaghi, Paolo Bruseghini, Carlo Morandi, Gian Luca Salvagno, Matteo Gelati, Gian Cesare Guidi, Silvio Bicciato, Stefano Schiaffino, Federico Schena, Carlo Capelli

https://doi.org/10.18632/aging.101016pp 1802—1821
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