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• Research PaperVolume 10, Issue 1pp 72-82

  Associations between the components of metabolic syndrome and the polymorphisms in the peroxisome proliferator-activated receptor gamma (PPAR-γ), the fat mass and obesity-associated (FTO), and the melanocortin-4 receptor (MC4R) genes

  Relevance score: 0.00

  Małgorzata Szkup, Aleksander Jerzy Owczarek, Daria Schneider-Matyka, Jacek Brodowski, Beata Łój, Elżbieta Grochans

  Keywords: PPAR gamma, receptor, melanocortin, type 4, FTO protein, human, metabolic syndrome X

  Published in Aging on January 9, 2018

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• Research PaperVolume 7, Issue 5pp 334-339

  Epigenetic age analysis of children who seem to evade aging

  Relevance score: 0.00

  Richard F. Walker, Jia Sophie Liu, Brock A. Peters, Beate R. Ritz, Timothy Wu, Roel A. Ophoff, Steve Horvath

  Keywords: slow aging, epigenetic clock, DNA methylation, biomarker of aging, syndrome X

  Published in Aging on May 15, 2015

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• Research PaperVolume 16, Issue 18pp 12593-12607

  Study of the role of leukocyte telomere length-related lncRNA NBR2 in Alzheimer’s disease

  Relevance score: 0.00

  Wenjie Li, Haoyan Chen, Xiaofan Yuan, Qi Yao, Mingjiong Zhang

  Keywords: Alzheimer’s syndrome, leukocyte telomere length, mendelian randomization analysis, lncRNA NBR2, GJA1

  Published in Aging on September 16, 2024

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• Research PaperVolume 13, Issue 1pp 1071-1095

  Integrated proteome and phosphoproteome analyses of peripheral blood mononuclear cells in primary Sjögren syndrome patients

  Relevance score: 0.00

  Shaoying Huang, Fengping Zheng, Lixiong Liu, Shuhui Meng, Wanxia Cai, Cantong Zhang, Weier Dai, Dongzhou Liu, Xiaoping Hong, Donge Tang, Yong Dai

  Keywords: primary Sjögren syndrome, peripheral blood mononuclear cells, phosphoproteome, biomarker

  Published in Aging on December 3, 2020

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• Research PaperVolume 13, Issue 19pp 22710-22731

  Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model

  Relevance score: 0.00

  Gustavo Satoru Kajitani, Lear Brace, Jose Humberto Trevino-Villarreal, Kaspar Trocha, Michael Robert MacArthur, Sarah Vose, Dorathy Vargas, Roderick Bronson, Sarah Jayne Mitchell, Carlos Frederico Martins Menck, James Robert Mitchell

  Keywords: Cockayne syndrome, CSA, XPA, segmental progeria, inflammation, vascular dysfunction

  Published in Aging on October 10, 2021

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• Research PaperVolume 13, Issue 5pp 7084-7095

  Paeoniflorin attenuates DHEA-induced polycystic ovary syndrome via inactivation of TGF-β1/Smads signaling pathway in vivo

  Relevance score: 0.00

  Jie Zhou, Yong Tan, Xudong Wang, Meihong Zhu

  Keywords: paeoniflorin, ovarian fibrosis, polycystic ovary syndrome, TGF-β1/Smads signaling pathway

  Published in Aging on February 26, 2021

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• Research PaperVolume 15, Issue 6pp 1734-1747

  Selenium as a predictor of metabolic syndrome in middle age women

  Relevance score: 0.00

  Daria Schneider-Matyka, Anna Maria Cybulska, Małgorzata Szkup, Bogumiła Pilarczyk, Mariusz Panczyk, Agnieszka Tomza-Marciniak, Elżbieta Grochans

  Keywords: selenium, metabolic syndrome, PPAR-γ, middle aged women

  Published in Aging on March 21, 2023

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• ReviewVolume 1, Issue 1pp 28-37

  Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A

  Relevance score: 0.00

  Phillip R. Musich, Yue Zou

  Keywords: Lamin A, Hutchinson-Gilford progeria syndrome, premature aging, Genome instability, DNA damage responses, XPA, DNA double strand breaks, DNA repair

  Published in Aging on January 16, 2009

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• Research PaperVolume 17, Issue 4pp 937-959

  Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferation

  Relevance score: 0.00

  Sofie Lautrup, Shi-Qi Zhang, Shinichiro Funayama, Lisa Lirussi, Tina Visnovska, Hoi-Hung Cheung, Marc Niere, Yuyao Tian, Hilde Loge Nilsen, Geir Selbæk, Janna Saarela, Yoshiro Maezawa, Koutaro Yokote, Per Nilsson, Wai-Yee Chan, Hisaya Kato, Mathias Ziegler, Vilhelm A. Bohr, Evandro F. Fang

  Keywords: Werner syndrome, premature aging, NAD+, mitochondria, proliferation

  Published in Aging on April 2, 2025

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• Research PaperVolume 16, Issue 22pp 13526-13533

  Less frequent skin ulcers among patients with Werner syndrome treated with pioglitazone: findings from the Japanese Werner Syndrome Registry

  Relevance score: 0.00

  Kazuto Aono, Masaya Koshizaka, Mayumi Shoji, Hiyori Kaneko, Yukari Maeda, Hisaya Kato, Yoshiro Maezawa, Makoto Miyabayashi, Mai Ishikawa, Akiko Sekiguchi, Sei-Ichiro Motegi, Shinji Tsukamoto, Akira Taniguchi, Yukiko Shoda, Toru Yoshimura, Junji Kawashima, Kayo Yoshinaga, Hironori Nakagami, Yoichi Takami, Ken Sugimoto, Kunihiko Hashimoto, Naoki Okubo, Takashi Yoshida, Masato Ohara, Asako Kogure, Daisuke Suzuki, Masafumi Kuzuya, Kazuhisa Watanabe, Minoru Takemoto, Junko Oshima, Koutaro Yokote

  Keywords: Werner syndrome, skin ulcer, metformin, pioglitazon, progeroid syndrome

  Published in Aging on December 2, 2024

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• Research PaperVolume 16, Issue 22pp 13505-13525

  When do the pathological signs become evident? Study of human mesenchymal stem cells in MDPL syndrome

  Relevance score: 0.00

  Spitalieri Paola, Guerrieri Lara, Murdocca Michela, Di Cesare Silvia, Maccaroni Serena, Pecorari Rosalba, Nardone Anna Maria, Candi Eleonora, Colasuonno Fiorella, Gori Giulia, Traficante Giovanna, Novelli Giuseppe, Sangiuolo Federica

  Keywords: MDPL syndrome, MSCs, aging, hiPSCs, POLD1 gene

  Published in Aging on November 26, 2024

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• Research PaperVolume 16, Issue 21pp 13271-13287

  Supplementation with nicotinamide limits accelerated aging in affected individuals with cockayne syndrome and restores antioxidant defenses

  Relevance score: 0.00

  Asma Chikhaoui, Kouloud Zayoud, Ichraf Kraoua, Sami Bouchoucha, Anis Tebourbi, Ilhem Turki, Houda Yacoub-Youssef

  Keywords: cockayne syndrome, segmental progeroid syndrome, oxidative-stress, niocotinamide, aging

  Published in Aging on November 26, 2024

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• Research PaperVolume 16, Issue 12pp 10203-10215

  Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome

  Relevance score: 0.00

  Sebastiano Giallongo, Jessica Ferrigno, Rosario Caltabiano, Giuseppe Broggi, Amer M. Alanazi, Alfio Distefano, Emanuela Tropea, Antonella Tramutola, Marzia Perluigi, Giovanni Li Volti, Eugenio Barone, Ignazio Alberto Barbagallo

  Keywords: Down Syndrome, oxidative stress, liver, aging

  Published in Aging on June 26, 2024

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• Research PaperVolume 16, Issue 10pp 8417-8445

  Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model

  Relevance score: 0.00

  Lucie Aumailley, Marie Julie Dubois, André Marette, Michel Lebel

  Keywords: proteomics, Werner syndrome, fatty liver, sexual dimorphism, immunoglobulins

  Published in Aging on May 24, 2024

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• Research PaperVolume 15, Issue 19pp 9948-9964

  Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome

  Relevance score: 0.00

  Daisuke Sawada, Hisaya Kato, Hiyori Kaneko, Daisuke Kinoshita, Shinichiro Funayama, Takuya Minamizuka, Atsushi Takasaki, Katsushi Igarashi, Masaya Koshizaka, Aki Takada-Watanabe, Rito Nakamura, Kazuto Aono, Ayano Yamaguchi, Naoya Teramoto, Yukari Maeda, Tomohiro Ohno, Aiko Hayashi, Kana Ide, Shintaro Ide, Mayumi Shoji, Takumi Kitamoto, Yusuke Endo, Hideyuki Ogata, Yoshitaka Kubota, Nobuyuki Mitsukawa, Atsushi Iwama, Yasuo Ouchi, Naoya Takayama, Koji Eto, Katsunori Fujii, Tomozumi Takatani, Tadashi Shiohama, Hiromichi Hamada, Yoshiro Maezawa, Koutaro Yokote

  Keywords: Werner syndrome, premature aging, lipodystrophy, stromal vascular fraction, SASP

  Published in Aging on October 3, 2023

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• Research PaperVolume 15, Issue 9pp 3273-3294

  Renal dysfunction, malignant neoplasms, atherosclerotic cardiovascular diseases, and sarcopenia as key outcomes observed in a three-year follow-up study using the Werner Syndrome Registry

  Relevance score: 0.00

  Yukari Maeda, Masaya Koshizaka, Mayumi Shoji, Hiyori Kaneko, Hisaya Kato, Yoshiro Maezawa, Junji Kawashima, Kayo Yoshinaga, Mai Ishikawa, Akiko Sekiguchi, Sei-Ichiro Motegi, Hironori Nakagami, Yoshihiko Yamada, Shinji Tsukamoto, Akira Taniguchi, Ken Sugimoto, Yoichi Takami, Yukiko Shoda, Kunihiko Hashimoto, Toru Yoshimura, Asako Kogure, Daisuke Suzuki, Naoki Okubo, Takashi Yoshida, Kazuhisa Watanabe, Masafumi Kuzuya, Minoru Takemoto, Junko Oshima, Koutaro Yokote

  Keywords: disease profile, long-term follow-up, malignant neoplasm, renal function, Werner syndrome

  Published in Aging on May 1, 2023

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• Research PaperVolume 15, Issue 7pp 2485-2502

  NR5A2 as a potential target for exercise to improve metabolic syndrome

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  Lingxiu Meng, Fusheng Dong, Junguo Deng

  Keywords: metabolic syndrome, movement, NR5A2, potential targets, cardiovascular diseases

  Published in Aging on March 26, 2023

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• EditorialVolume 15, Issue 2pp 295-297

  Pathological trajectory in the Ts65Dn model of Down syndrome

  Relevance score: 0.00

  Savannah Tallino, Wendy Winslow, Ramon Velazquez

  Keywords: Down syndrome, Ts65Dn, amyloid-beta, cholinergic

  Published in Aging on January 20, 2023

• Research PaperVolume 14, Issue 13pp 5299-5310

  Cockayne syndrome without UV-sensitivity in Vietnamese siblings with novel ERCC8 variants

  Relevance score: 0.00

  Nguyen Thuy Duong, Tran Huu Dinh, Britta S. Möhl, Stefan Hintze, Do Hai Quynh, Duong Thi Thu Ha, Ngo Diem Ngoc, Vu Chi Dung, Noriko Miyake, Nong Van Hai, Naomichi Matsumoto, Peter Meinke

  Keywords: Cockayne syndrome, DNA excision repair, ERCC8, segmental progeroid disease

  Published in Aging on June 22, 2022

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• Research PaperVolume 14, Issue 3pp 1351-1373

  Identification and external validation of the hub genes associated with cardiorenal syndrome through time-series and network analyses

  Relevance score: 0.00

  Jingjing Liang, Xiaohui Huang, Weiwen Li, Yunzhao Hu

  Keywords: cardiorenal syndrome, FN1, POSTN, diagnosis, biomarker

  Published in Aging on February 8, 2022

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