Volume 10, Issue 1

January 2018
pp 1—153

About the Cover

The cover for issue 1 of Aging features Figure 6 "Schematic summary of effects of senescence, Ang II and BACE1 inhibitor IV on expression and processing of APP in human BMECs" from Sun et al.

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Editorials

Epigenetics: the panacea for cognitive decline?

Mahima Sharma, Radha Raghuraman, Sreedharan Sajikumar,

https://doi.org/10.18632/aging.101366 pp 1—2

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Epithelial plasticity in cancer: beyond metastasis

Timothy M. Thomson, Pedro L. Fernández,

https://doi.org/10.18632/aging.101367 pp 3—4

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The neuronal Shc adaptor in Alzheimer’s Disease

Viviana Triaca, Roberto Coccurello, Giacomo Giacovazzo,

https://doi.org/10.18632/aging.101368 pp 5—6

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rRNA-gene methylation and biological aging

Patrizia D’Aquila, Dina Bellizzi, Giuseppe Passarino,

https://doi.org/10.18632/aging.101369 pp 7—8

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The stromal fibrosis in aging ovary

Takashi Umehara, JoAnne S. Richards, Masayuki Shimada,

https://doi.org/10.18632/aging.101370 pp 9—10

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Targeting LSD2 in breast cancer

Yi Huang, Yongmei Yin, Min Sun,

https://doi.org/10.18632/aging.101371 pp 11—12

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SLPI: a new target for stopping metastasis

Lance L. Munn, Igor Garkavtsev,

https://doi.org/10.18632/aging.101372 pp 13—14

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Cross-organelle communication at the core of longevity

Nuno Raimundo, Anita Kriško,

https://doi.org/10.18632/aging.101373 pp 15—16

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Stem cell depletion by inflammation-associated miR-155

Takeshi Teramura, Yuta Onodera,

https://doi.org/10.18632/aging.101374 pp 17—18

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Research Papers

Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline

Claudia Schwarz, Slaven Stekovic, Miranka Wirth, Gloria Benson, Philipp Royer, Stephan J Sigrist, Thomas Pieber, Christopher Dammbrueck, Christoph Magnes, Tobias Eisenberg, Tobias Pendl, Jens Bohlken, Theresa Köbe, Frank Madeo, Agnes Flöel,

https://doi.org/10.18632/aging.101354 pp 19—33

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Muscle function decline and mitochondria changes in middle age precede sarcopenia in mice

Andrea del Campo, Ignacio Contreras-Hernández, Mauricio Castro-Sepúlveda, Cristian A. Campos, Reinaldo Figueroa, María Florencia Tevy, Verónica Eisner, Mariana Casas, Enrique Jaimovich,

https://doi.org/10.18632/aging.101358 pp 34—55

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NKILA inhibits NF-κB signaling and suppresses tumor metastasis

Shun Ke, Rui-chao Li, Fan-kai Meng, Ming-hao Fang,

https://doi.org/10.18632/aging.101359 pp 56—71

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Associations between the components of metabolic syndrome and the polymorphisms in the peroxisome proliferator-activated receptor gamma (PPAR-γ), the fat mass and obesity-associated (FTO), and the melanocortin-4 receptor (MC4R) genes

Małgorzata Szkup, Aleksander Jerzy Owczarek, Daria Schneider-Matyka, Jacek Brodowski, Beata Łój, Elżbieta Grochans,

https://doi.org/10.18632/aging.101360 pp 72—82

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Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury

Eun Nim Kim, Ji Hee Lim, Min Young Kim, Tae Hyun Ban, In-Ae Jang, Hye Eun Yoon, Cheol Whee Park, Yoon Sik Chang, Bum Soon Choi,

https://doi.org/10.18632/aging.101361 pp 83—99

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Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells

Ruohan Sun, Tongrong He, Yujun Pan, Zvonimir S. Katusic,

https://doi.org/10.18632/aging.101362 pp 100—114

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HOXC6 predicts invasion and poor survival in hepatocellular carcinoma by driving epithelial-mesenchymal transition

Pin-Dong Li, Peng Chen, Xin Peng, Charlie Ma, Wen-Jie Zhang, Xiao-Fang Dai,

https://doi.org/10.18632/aging.101363 pp 115—130

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Rapamycin prevents the intervertebral disc degeneration via inhibiting differentiation and senescence of annulus fibrosus cells

Changhong Gao, Bin Ning, Chenglin Sang, Ying Zhang,

https://doi.org/10.18632/aging.101364 pp 131—143

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Predictors of gait speed and its change over three years in community-dwelling older people

Daniela Pinter, Stuart J. Ritchie, Thomas Gattringer, Mark E. Bastin, Maria del C. Valdés Hernández, Janie Corley, Susana Muñoz Maniega, Alison Pattie, David A. Dickie, Alan J. Gow, John M. Starr, Ian J. Deary, Christian Enzinger, Franz Fazekas, Joanna Wardlaw,

https://doi.org/10.18632/aging.101365 pp 144—153

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