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Page: 12345 of 5

• Research PaperVolume 17, Issue 5pp 1091-1104

  Defining the hypoxic thresholds that trigger blood-brain barrier disruption: the effect of age

  Relevance score: 0.00

  Arjun Sapkota, Sebok K. Halder, Richard Milner

  Keywords: blood-brain barrier integrity, endothelial, proliferation, microglia, chronic mild hypoxia, hypoxic threshold

  Published in Aging on May 1, 2025

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• EditorialVolume 15, Issue 3pp 597-598

  Harnessing the vasculo-protective potential of microglia

  Relevance score: 0.00

  Sebok K. Halder, Arjun Sapkota, Richard Milner

  Keywords: blood-brain barrier integrity, chronic mild hypoxia, microglia, aging, endothelial cells

  Published in Aging on February 1, 2023

• Research PaperVolume 11, Issue 23pp 11391-11415

  Melatonin protects blood-brain barrier integrity and permeability by inhibiting matrix metalloproteinase-9 via the NOTCH3/NF-κB pathway

  Relevance score: 0.00

  Weiwei Qin, Jing Li, Rongjia Zhu, Suhua Gao, Junfen Fan, Mingrong Xia, Robert Chunhua Zhao, Jiewen Zhang

  Keywords: blood-brain barrier, pericytes, matrix metalloproteinase-9, nuclear factor κB, NOTCH3

  Published in Aging on December 7, 2019

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• Research PaperVolume 11, Issue 22pp 10167-10182

  Tissue plasminogen activator disrupts the blood-brain barrier through increasing the inflammatory response mediated by pericytes after cerebral ischemia

  Relevance score: 0.00

  Eryan Yang, Ying Cai, Xiuhua Yao, Ji Liu, Qixue Wang, Weili Jin, Qiaoli Wu, Weijia Fan, Lina Qiu, Chunsheng Kang, Jialing Wu

  Keywords: blood-brain barrier, cerebrovascular disease, inflammation, pericyte, tPA

  Published in Aging on November 18, 2019

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• Research PaperVolume 16, Issue 4pp 3750-3762

  Suppression of cerebral ischemia injury induced blood brain barrier breakdown by dexmedetomidine via promoting CCN1

  Relevance score: 0.00

  Shuangmei Liu, Xuepeng Jia, Bo Liu, Yue Liu, Hong Yin

  Keywords: dexmedetomidine, cerebral ischemia injury, blood brain barrier, CCN1, middle cerebral artery occlusion

  Published in Aging on February 15, 2024

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• Research PaperVolume 16, Issue 7pp 6135-6146

  Lifibrate attenuates blood-brain barrier damage following ischemic stroke via the MLCK/p-MLC/ZO-1 axis

  Relevance score: 0.00

  Yu Duan, Yao Deng, Feng Tang, Jian Li

  Keywords: Lifibrate, stroke, blood-brain barrier, tight junction proteins, ZO-1

  Published in Aging on March 27, 2024

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• Research PaperVolume 15, Issue 20pp 10972-10995

  Chronic kidney disease causes blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2 and insolubility of tau protein

  Relevance score: 0.00

  Hisazumi Matsuki, Shintaro Mandai, Hiroki Shiwaku, Takaaki Koide, Naohiro Takahashi, Tomoki Yanagi, Shunsuke Inaba, Saaya Ida, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Eisei Sohara, Hidehiko Takahashi, Shinichi Uchida

  Keywords: chronic kidney disease, cognitive impairment, blood brain barrier, proteomics, urea

  Published in Aging on October 25, 2023

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• Research PaperVolume 16, Issue 7pp 5905-5915

  Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway

  Relevance score: 0.00

  Yunfang Yang, Changjiang Li, Sijin Yang, Zhuo Zhang, Xue Bai, Hongmei Tang, Jiang Huang

  Keywords: stroke, Cepharanthine, zonula occludens-1 (ZO-1), blood-brain barrier (BBB), hypoxia/reperfusion (H/R)

  Published in Aging on March 21, 2024

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• Research PaperVolume 13, Issue 4pp 4999-5019

  HOXB9 enhances the ability of lung cancer cells to penetrate the blood-brain barrier

  Relevance score: 0.00

  HongShan Zheng, ChenLong Li, ZhenZhe Li, KaiBin Zhu, HongBo Bao, JinSheng Xiong, Peng Liang

  Keywords: brain metastasis, non-small cell lung cancer, blood-brain barrier, HOXB9, epithelial-to-mesenchymal transition

  Published in Aging on December 19, 2020

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• Research PaperVolume 15, Issue 6pp 1931-1943

  Exosomal miR-370-3p increases the permeability of blood-brain barrier in ischemia/reperfusion stroke of brain by targeting MPK1

  Relevance score: 0.00

  Caifeng Gu, Weichun Mo, Kunlun Wang, Mingqiang Gao, Junfeng Chen, Feng Zhang, Jie Shen

  Keywords: stroke, blood-brain barrier, ischemia/reperfusion, exosomes, mir-370-3p

  Published in Aging on March 8, 2023

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• Research PaperVolume 13, Issue 12pp 16816-16833

  Celastrol protects against early brain injury after subarachnoid hemorrhage in rats through alleviating blood-brain barrier disruption and blocking necroptosis

  Relevance score: 0.00

  Hangzhe Xu, Yong Cai, Mengyan Yu, Jing Sun, Jing Cai, Jingbo Li, Bing Qin, Guangyu Ying, Ting Chen, Yongfeng Shen, Liyong Jie, Demin Xu, Chi Gu, Chun Wang, XiaoYi Hu, Jingsen Chen, Lin Wang, Gao Chen

  Keywords: subarachnoid hemorrhage, early brain injury, celastrol, blood-brain barrier, necroptosis

  Published in Aging on June 28, 2021

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• Research PaperVolume 13, Issue 5pp 7644-7659

  Platelets transport β-amyloid from the peripheral blood into the brain by destroying the blood-brain barrier to accelerate the process of Alzheimer's disease in mouse models

  Relevance score: 0.00

  Tong Wu, Lizhi Chen, Lingqi Zhou, Jie Xu, Kaihua Guo

  Keywords: Alzheimer’s disease, platelets, blood-brain barrier, aspirin, β-amyloid

  Published in Aging on March 5, 2021

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• Research PaperVolume 12, Issue 12pp 11768-11780

  L-3-n-butylphthalide attenuates inflammation response and brain edema in rat intracerebral hemorrhage model

  Relevance score: 0.00

  Zhou Zeng, Xiyu Gong, Zhiping Hu

  Keywords: L-3-n-butylphthalide, intracerebral hemorrhage, blood-brain barrier, brain edema, anti-inflammation

  Published in Aging on June 21, 2020

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• Research PaperVolume 17, Issue 2pp 448-463

  Chronic β3 adrenergic agonist treatment improves neurovascular coupling responses, attenuates blood-brain barrier leakage and neuroinflammation, and enhances cognition in aged mice

  Relevance score: 0.00

  Duraipandy Natarajan, Shoba Ekambaram, Stefano Tarantini, Raghavendra Y. Nagaraja, Andriy Yabluchanskiy, Andria F. Hedrick, Vibhudutta Awasthi, Madhan Subramanian, Anna Csiszar, Priya Balasubramanian

  Keywords: vascular cognitive impairment, endothelial function, glucose uptake, beta 3 adrenergic receptor agonist, blood-brain barrier leakage

  Published in Aging on February 19, 2025

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• Research PaperVolume 8, Issue 11pp 2814-2826

  Caloric restriction preserves memory and reduces anxiety of aging mice with early enhancement of neurovascular functions

  Relevance score: 0.00

  Ishita Parikh, Janet Guo, Kai-Hsiang Chuang, Yu Zhong, Ralf G. Rempe, Jared D. Hoffman, Rachel Armstrong, Björn Bauer, Anika M.S. Hartz, Ai-Ling Lin

  Keywords: caloric restriction, magnetic resonance imaging (MRI), cerebral blood flow, blood-brain barrier, mammalian target of rapamcyin (mTOR), cognition, anxiety

  Published in Aging on November 8, 2016

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• Research PaperVolume 15, Issue 18pp 9426-9437

  The mechanism of simultaneous intake of Jujuboside A and B in the regulation of sleep at the hypothalamic level

  Relevance score: 0.00

  Wei Wang, Yi Wang, Hongyan Pei, Mingming Li, Aozhe Zhu, Rui Du, Gao Jun Peng

  Keywords: jujuboside, quantitative proteomics, bioinformatics, improvement sleep, blood-brain barrier

  Published in Aging on September 5, 2023

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• EditorialVolume 14, Issue 9pp 3726-3727

  Developments in NEW triad research

  Relevance score: 0.00

  Shawn N. Whitehead, Vladimir Hachinski, Alexander Levit

  Keywords: dementia, executive function, white matter, neurovascular unit, blood-brain barrier

  Published in Aging on May 4, 2022

• EditorialVolume 11, Issue 5pp 1331-1332

  mTOR in cerebrovascular disease

  Relevance score: 0.00

  Candice E. Van Skike, Veronica Galvan

  Keywords: mTOR, Alzheimer’s disease, vascular cognitive impairment, atherosclerosis, blood-brain barrier

  Published in Aging on March 13, 2019

• EditorialVolume 11, Issue 5pp 1329-1330

  microRNA-based biomarker for dementia

  Relevance score: 0.00

  Kensuke Toyama, Masaki Mogi, Philip S. Tsao

  Keywords: microRNAs, exosome, dementia, blood-brain barriers, miR-501-3p

  Published in Aging on March 12, 2019

• Research PaperVolume 12, Issue 5pp 4348-4356

  Brain hemodynamic changes in amnestic mild cognitive impairment measured by pulsed arterial spin labeling

  Relevance score: 0.00

  Xiangbin Wang, Ding Ding, Qianhua Zhao, Xiaoniu Liang, Ling Peng, Xiaohu Zhao, Qian Xi, Zhang Min, Wei Wang, Xiaowen Xu, Qihao Guo, Pei-Jun Wang

  Keywords: amnestic mild cognitive impairment, pulsed arterial spin labeling, magnetic resonance imaging, cerebral blood flow, brain compensatory mechanism

  Published in Aging on March 12, 2020

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