Submit an Article
Online ISSN: 1945-4589
Impact Journals, LLC. is the publisher of Aging: www.impactjournals.com.
Impact Journals is a member of the Wellcome Trust List of Compliant Publishers.
Impact Journals is a member of the Society for Scholarly Publishing.
Learn about our FREE Post-Publication Promotion Services
The cover features Figure 1 "Stemness levels during human aging" from Dos Santos et al.

Volume 16, Issue 7

15 April, 2024
pp 5796—6630

About the Cover

The cover features Figure 1 "Stemness levels during human aging" from Dos Santos et al.


Explore This Issue

Research Papers

Evidence of a pan-tissue decline in stemness during human aging

Gabriel Arantes dos Santos, Gustavo Daniel Vega Magdaleno, João Pedro de Magalhães,
https://doi.org/10.18632/aging.205717 pp 5796—5810
View Abstract PDF Full-Text How to Cite

The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats

Jennifer M. Rutkowsky, Zabrisky Roland, Anthony Valenzuela, An B. Nguyen, Heui Hye Park, Natalie Six, Ilknur Dursun, Kyoungmi Kim, Pamela J. Lein, Jon J. Ramsey,
https://doi.org/10.18632/aging.205741 pp 5811—5828
View Abstract PDF Full-Text How to Cite

The coupling between healthspan and lifespan in Caenorhabditis depends on complex interactions between compound intervention and genetic background

Stephen A. Banse, E. Grace Jackson, Christine A. Sedore, Brian Onken, David Hall, Anna Coleman-Hulbert, Phu Huynh, Theo Garrett, Erik Johnson, Girish Harinath, Delaney Inman, Suzhen Guo, Mackenzie Morshead, Jian Xue, Ron Falkowski, Esteban Chen, Christopher Herrera, Allie J. Kirsch, Viviana I. Perez, Max Guo, Gordon J. Lithgow, Monica Driscoll, Patrick C. Phillips,
https://doi.org/10.18632/aging.205743 pp 5829—5855
View Abstract PDF Full-Text How to Cite

miR-30d-5p inhibits proliferation, invasion and migration of breast cancer cells by targeting SERPINE1 and promoting fatty acid β-oxidation

Lina Zhang, Shuguang Ren, Yang Sang, Yueyang Hu, Cong Wang, Xinrui Wang, Yuntao Li,
https://doi.org/10.18632/aging.205587 pp 5856—5865
View Abstract PDF Full-Text How to Cite

NXPH4 can be used as a biomarker for pan-cancer and promotes colon cancer progression

Zhipeng Zhang, Pengfei Wang, Siwen Chen, Dezhi Xiang, Jinzhen Chen, Wanchang Huang, Xiao Liu, Tongwen Yi, Dawei Wang, Yunfei Pu, Longfu He, Hao Zhang,
https://doi.org/10.18632/aging.205648 pp 5866—5886
View Abstract PDF Full-Text How to Cite

Cordyceps sinensis extract protects against acute kidney injury by inhibiting perforin expression in NK cells via the STING/IRF3 pathway

Shuang Li, Wei Pang, Yuzhu Wang, Yiting Zhang,
https://doi.org/10.18632/aging.205676 pp 5887—5904
View Abstract PDF Full-Text How to Cite

Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway

Yunfang Yang, Changjiang Li, Sijin Yang, Zhuo Zhang, Xue Bai, Hongmei Tang, Jiang Huang,
https://doi.org/10.18632/aging.205678 pp 5905—5915
View Abstract PDF Full-Text How to Cite

Downregulating miRNA-199a-5p exacerbates fluorouracil-induced cardiotoxicity by activating the ATF6 signaling pathway

Wei Wang, Liang Dong, Hengxu Lv, Yonghui An, Changwang Zhang, Zheng Zheng, Ying Guo, Li He, Libin Wang, Jinmei Wang, Xinlei Shi, Na Li, Mingqi Zheng,
https://doi.org/10.18632/aging.205679 pp 5916—5928
View Abstract PDF Full-Text How to Cite

RNA splicing regulator EIF3D regulates the tumor microenvironment through immunogene-related alternative splicing in head and neck squamous cell carcinoma

Dandan Lu, Mijti Mihoayi, Yimin Ablikim, Abdeyrim Arikin,
https://doi.org/10.18632/aging.205681 pp 5929—5948
View Abstract PDF Full-Text How to Cite

Identification of key pathways and mRNAs in interstitial cystitis/bladder pain syndrome treatment with quercetin through bioinformatics analysis of mRNA-sequence data

Guang Wang, Pei Li, Si-Wei Su, Rui Xu, Zi-Ye Huang, Tong-Xin Yang, Jiong-Ming Li,
https://doi.org/10.18632/aging.205682 pp 5949—5966
View Abstract PDF Full-Text How to Cite

Identification and validation of DHCR7 as a diagnostic biomarker involved in the proliferation and mitochondrial function of breast cancer

Yanfeng Wang, Jiaxin Fan, Yongcheng Liu, Jie Du, Boyu Liang, Huxia Wang, Zhangjun Song,
https://doi.org/10.18632/aging.205683 pp 5967—5986
View Abstract PDF Full-Text How to Cite

Identification and validation of the biomarkers related to ferroptosis in calcium oxalate nephrolithiasis

Chao Hou, Bing Zhong, Shuo Gu, Yunyan Wang, Lu Ji,
https://doi.org/10.18632/aging.205684 pp 5987—6007
View Abstract PDF Full-Text How to Cite

Novel insights into the pathogenesis of thyroid eye disease through ferroptosis-related gene signature and immune infiltration analysis

Yunyan Ye, Lei Dai, Joseph Mugaanyi, Weina Fu, Feng Hu,
https://doi.org/10.18632/aging.205685 pp 6008—6034
View Abstract PDF Full-Text How to Cite

Exploration of signature based on T cell-related genes in stomach adenocarcinoma by analysis of single cell sequencing data

Huimei Wang, Nan An, Aiyue Pei, Yongxiao Sun, Shuo Li, Si Chen, Nan Zhang,
https://doi.org/10.18632/aging.205687 pp 6035—6053
View Abstract PDF Full-Text How to Cite

Identification of a novel disulfideptosis-related gene signature for prognostic implication in lower-grade gliomas

Fuqiang Zhang, Meihong Lv, Yi He,
https://doi.org/10.18632/aging.205688 pp 6054—6067
View Abstract PDF Full-Text How to Cite

Associations of PD-1 and PD-L1 gene polymorphisms with cancer risk: a meta-analysis based on 50 studies

Maoquan Yang, Yan Liu, Shuangshuang Zheng, Peizhen Geng, Tianhao He, Linan Lu, Yikuan Feng, Qiqi Jiang,
https://doi.org/10.18632/aging.205689 pp 6068—6097
View Abstract PDF Full-Text How to Cite

The necroptosis-related signature and tumor microenvironment immune characteristics associated with clinical prognosis and drug sensitivity analysis in stomach adenocarcinoma

Biao Yang, Yingnan Wang, Tao Liu, Meijing Zhang, Tianhang Luo,
https://doi.org/10.18632/aging.205690 pp 6098—6117
View Abstract PDF Full-Text How to Cite

A novel risk signature based on liquid-liquid phase separation-related genes reveals prognostic and tumour microenvironmental features in clear cell renal cell carcinoma

Qing Lu, Ping Xi, Suling Xu, Zhicheng Zhang, Binbin Gong, Ji Liu, Qiqi Zhu, Ting Sun, Shaoxing Zhu, Ru Chen,
https://doi.org/10.18632/aging.205691 pp 6118—6134
View Abstract PDF Full-Text How to Cite

Lifibrate attenuates blood-brain barrier damage following ischemic stroke via the MLCK/p-MLC/ZO-1 axis

Yu Duan, Yao Deng, Feng Tang, Jian Li,
https://doi.org/10.18632/aging.205692 pp 6135—6146
View Abstract PDF Full-Text How to Cite

Poria cocos polysaccharides improve alcoholic liver disease by interfering with ferroptosis through NRF2 regulation

Xiangyu Zhou, Jincheng Wang, Sufang Zhou,
https://doi.org/10.18632/aging.205693 pp 6147—6162
View Abstract PDF Full-Text How to Cite

KIF3C: an emerging biomarker with prognostic and immune implications across pan-cancer types and its experiment validation in gastric cancer

Qiangqiang Zhong, Wenbo Hong, Lina Xiong,
https://doi.org/10.18632/aging.205694 pp 6163—6187
View Abstract PDF Full-Text How to Cite

Potential value of expression of receptor accessory protein 4 for evaluating the prognosis of lower-grade glioma patients

Shuping Luo, Zhendong Liu, Haigang Chang, Xingbo Cheng, Rongjun Qian, Yanzheng Gao, Chaofeng Hou,
https://doi.org/10.18632/aging.205695 pp 6188—6211
View Abstract PDF Full-Text How to Cite

A retrospective study on the effect of Chinese patent medicine combined with conventional treatment on the survival outcomes of 313 patients with stage II–III NSCLC

Kegang Jia, Chenxu Zhang, Fang Li, Bin He, Shenglong Xie, Jun Du, Gang Feng,
https://doi.org/10.18632/aging.205697 pp 6212—6228
View Abstract PDF Full-Text How to Cite

Role of CCR1/5/7 in hepatocellular carcinoma: a study on prognostic evaluation, molecular subtyping, and association with immune infiltration

Huasheng Huang, Chenlu Lan, Yongguang Wei, Jusen Nong, Xiwen Liao, Xinping Ye, Ganlu Deng, Tao Peng, Xin Zhou,
https://doi.org/10.18632/aging.205698 pp 6229—6261
View Abstract PDF Full-Text How to Cite

Identification and characterization of circular RNAs expression profiles in obstructive sleep apnea-induced liver injury

Chaowei Li, Jinhuang Lin, Qingshi Chen, Yueyong Zhu,
https://doi.org/10.18632/aging.205701 pp 6262—6272
View Abstract PDF Full-Text How to Cite

Human umbilical cord-derived mesenchymal stem cells and auto-crosslinked hyaluronic acid gel complex for treatment of intrauterine adhesion

Jiaying Fan, Jingying Xie, Yunsheng Liao, Baoyu Lai, Guixin Zhou, Wenqin Lian, Jian Xiong,
https://doi.org/10.18632/aging.205704 pp 6273—6289
View Abstract PDF Full-Text How to Cite

Identifying an immunogenic cell death-related gene signature contributes to predicting prognosis, immunotherapy efficacy, and tumor microenvironment of lung adenocarcinoma

Xue Li, Dengfeng Zhang, Pengfei Guo, Shaowei Ma, Shaolin Gao, Shujun Li, Yadong Yuan,
https://doi.org/10.18632/aging.205705 pp 6290—6313
View Abstract PDF Full-Text How to Cite

Machine learning identifies novel coagulation genes as diagnostic and immunological biomarkers in ischemic stroke

Jinzhi Liu, Zhihua Si, Ju Liu, Xu Zhang, Cong Xie, Wei Zhao, Aihua Wang, Zhangyong Xia,
https://doi.org/10.18632/aging.205706 pp 6314—6333
View Abstract PDF Full-Text How to Cite

Lactobacillus plantarum 45 activates SHP2 through inhibition of oxidative stress to regulate osteoblast and osteoclast differentiation

Yaming Yang, Zheng Yan, Qi Xie, Yong Wang, Zhiying Liu, Min Lei,
https://doi.org/10.18632/aging.205708 pp 6334—6347
View Abstract PDF Full-Text How to Cite

Inflammatory risk of albumin combined with C-reactive protein predicts long-term cardiovascular risk in patients with diabetes

Xiaoqun Xu, Houyong Zhu, Hanxin Wang, Xinyu Zhu, Libin Liu, Fengwei Zhang, Hongjuan Zhou, Mingzhi Zhu, Lingshan Dai, Long Cai,
https://doi.org/10.18632/aging.205709 pp 6348—6363
View Abstract PDF Full-Text How to Cite

Metabolic score for insulin resistance predicts major adverse cardiovascular event in premature coronary artery disease

Dachuan Guo, Chong Zhang, Mingyan Zhang, Zhenguo Wu, Xiaoyu Liu, Yerui Zhang, Li Liu, Meili Sun, Jianmin Yang,
https://doi.org/10.18632/aging.205710 pp 6364—6383
View Abstract PDF Full-Text How to Cite

Using genetics and proteomics data to identify proteins causally related to COVID-19, healthspan and lifespan: a Mendelian randomization study

Jie V. Zhao, Minhao Yao, Zhonghua Liu,
https://doi.org/10.18632/aging.205711 pp 6384—6416
View Abstract PDF Full-Text How to Cite

Pan-cancer analysis of Sushi domain-containing protein 4 (SUSD4) and validated in colorectal cancer

Yuchen Zhong, Chaojing Zheng, Weiyuan Zhang, Hongyu Wu, Qian Zhang, Dechuan Li, Haixing Ju, Haiyang Feng, Yinbo Chen, Yongtian Fan, Weiping Chen, Meng Wang, Guiyu Wang,
https://doi.org/10.18632/aging.205712 pp 6417—6444
View Abstract PDF Full-Text How to Cite

Risk assessment of extra-uterine involvement and prognosis in young type I endometrial carcinoma with high or moderate differentiation and less than 1/2 myometrial invasion

Yi Sun, Pin Han, Yuanpei Wang, Xiaoran Cheng, Weijia Wu, Qianwen Liu, Fang Ren,
https://doi.org/10.18632/aging.205714 pp 6445—6454
View Abstract PDF Full-Text How to Cite

Machine learning for identifying tumor stemness genes and developing prognostic model in gastric cancer

Guo-Xing Li, Yun-Peng Chen, You-Yang Hu, Wen-Jing Zhao, Yun-Yan Lu, Fu-Jian Wan, Zhi-Jun Wu, Xiang-Qian Wang, Qi-Ying Yu,
https://doi.org/10.18632/aging.205715 pp 6455—6477
View Abstract PDF Full-Text How to Cite

Stigmasterol alleviates airway inflammation in OVA-induced asthmatic mice via inhibiting the TGF-β1/Smad2 and IL-17A signaling pathways

Sihong Huang, Rong Zhou, Yuyun Yuan, Yiyun Shen,
https://doi.org/10.18632/aging.205716 pp 6478—6487
View Abstract PDF Full-Text How to Cite

Multidimensional data analysis revealed thyroiditis-associated TCF19 SNP rs2073724 as a highly ranked protective variant in thyroid cancer

Xianhui Ruan, Yu Liu, Shuping Wu, Guiming Fu, Mei Tao, Yue Huang, Dapeng Li, Songfeng Wei, Ming Gao, Shicheng Guo, Junya Ning, Xiangqian Zheng,
https://doi.org/10.18632/aging.205718 pp 6488—6509
View Abstract PDF Full-Text How to Cite

has-miR-134-5p inhibits the proliferation and migration of glioma cells by regulating the BDNF/ERK signaling pathway

Zeshang Guo, Pingxv An, Xinyu Hong,
https://doi.org/10.18632/aging.205720 pp 6510—6520
View Abstract PDF Full-Text How to Cite

Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H2S generation

Tursunay Dilxat, Qiang Shi, Xiaofan Chen, Xuxin Liu,
https://doi.org/10.18632/aging.205721 pp 6521—6536
View Abstract PDF Full-Text How to Cite

A prognostic signature established based on genes related to tumor microenvironment for patients with hepatocellular carcinoma

Zhongfeng Cui, Ge Li, Yanbin Shi, Xiaoli Zhao, Juan Wang, Shanlei Hu, Chunguang Chen, Guangming Li,
https://doi.org/10.18632/aging.205722 pp 6537—6549
View Abstract PDF Full-Text How to Cite

Single-cell data revealed exhaustion of characteristic NK cell subpopulations and T cell subpopulations in hepatocellular carcinoma

Zhongfeng Cui, Hongzhi Li, Chunli Liu, Juan Wang, Chunguang Chen, Shanlei Hu, Xiaoli Zhao, Guangming Li,
https://doi.org/10.18632/aging.205723 pp 6550—6565
View Abstract PDF Full-Text How to Cite

Transcranial direct current stimulation promotes angiogenesis and improves neurological function via the OXA-TF-AKT/ERK signaling pathway in traumatic brain injury

Bingkai Ren, Junwei Kang, Yan Wang, Xiangqiang Meng, Ying Huang, Yang Bai, Zhen Feng,
https://doi.org/10.18632/aging.205724 pp 6566—6587
View Abstract PDF Full-Text How to Cite

TGF-β downstream of Smad3 and MAPK signaling antagonistically regulate the viability and partial epithelial–mesenchymal transition of liver progenitor cells

Yi-Min Sun, Yu Wu, Gan-Xun Li, Hui-Fang Liang, Tu-Ying Yong, Zifu Li, Bixiang Zhang, Xiao-Ping Chen, Guan-Nan Jin, Ze-Yang Ding,
https://doi.org/10.18632/aging.205725 pp 6588—6612
View Abstract PDF Full-Text How to Cite

Review

The mechanism of USP43 in the development of tumor: a literature review

Ziqi Zhao, Meichen Liu, Zhikun Lin, Mengru Zhu, Linlin Lv, Xinqing Zhu, Rui Fan, Abdullah Al-Danakh, Hui He, Guang Tan,
https://doi.org/10.18632/aging.205731 pp 6613—6626
View Abstract PDF Full-Text How to Cite

Corrections

Correction for: Inhibition of circulating exosomal microRNA-15a-3p accelerates diabetic wound repair

Yuan Xiong, Lang Chen, Tao Yu, Chenchen Yan, Wu Zhou, Faqi Cao, Xiaomeng You, Yingqi Zhang, Yun Sun, Jing Liu, Hang Xue, Yiqiang Hu, Dong Chen, Bobin Mi, Guohui Liu,
https://doi.org/10.18632/aging.205514 pp 6627—6628
PDF Full-Text How to Cite

Correction for: MTDH promotes metastasis of clear cell renal cell carcinoma by activating SND1-mediated ERK signaling and epithelial-mesenchymal transition

Anbang He, Shiming He, Cong Huang, Zhicong Chen, Yucai Wu, Yanqing Gong, Xuesong Li, Liqun Zhou,
https://doi.org/10.18632/aging.205603 pp 6629—6630
PDF Full-Text How to Cite
Volume 16, Issue 7  
Table of Contents