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• Research PaperVolume 17, Issue 8pp 2079-2088

  What is the clinical evidence to support off-label rapamycin therapy in healthy adults?

  Relevance score: 0.00

  Jacob M. Hands, Michael S. Lustgarten, Leigh A. Frame, Bradley Rosen

  Keywords: rapamycin, aging, mTOR

  Published in Aging on August 7, 2025

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• Research PaperVolume 17, Issue 4pp 908-936

  Influence of rapamycin on safety and healthspan metrics after one year: PEARL trial results

  Relevance score: 0.00

  Mauricio Moel, Girish Harinath, Virginia Lee, Andy Nyquist, Stefanie L. Morgan, Anar Isman, Sajad Zalzala

  Keywords: rapamycin, aging, healthspan, longevity, geroscience

  Published in Aging on April 4, 2025

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• Research PaperVolume 17, Issue 2pp 550-562

  Variability in radiotherapy outcomes across cancer types: a comparative study of glioblastoma multiforme and low-grade gliomas

  Relevance score: 0.00

  Alexander Veviorskiy, Garik V. Mkrtchyan, Andreyan N. Osipov, Evgeny Izumchenko, Ivan V. Ozerov, Alex Aliper, Alex Zhavoronkov, Morten Scheibye-Knudsen

  Keywords: cancer, biomarkers, radiotherapy, GBM, LGG, survival

  Published in Aging on February 27, 2025

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• Priority ReviewVolume 17, Issue 1pp 1-15

  Mikhail ‘Misha’ Blagosklonny’s enduring legacy in geroscience: the hyperfunction theory and the therapeutic potential of rapamycin

  Relevance score: 0.00

  David A. Barzilai

  Keywords: rapamycin, longevity medicine, healthspan, geroscience, hyperfunction

  Published in Aging on January 12, 2025

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• Research PaperVolume 16, Issue 5pp 4169-4190

  RAB22A as a predictor of exosome secretion in the progression and relapse of multiple myeloma

  Relevance score: 0.00

  Bingjie Fan, Li Wang, Jishi Wang

  Keywords: RAB22A, exosome secretion, EMT, multiple myeloma, immune regulation

  Published in Aging on March 1, 2024

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• Research PaperVolume 16, Issue 2pp 1696-1711

  Therapeutic strategies and predictive models for Xp11.2 translocation/TFE3 gene fusion renal cell carcinoma in adults based on data of two Chinese medical centers

  Relevance score: 0.00

  Yunkai Yang, Changfeng Zhao, Zhida Wang, Feng Liu, Ming Zhao, Huiwen Yang, Jun Chen, Xuejing Chen, Min Shi, Dixing Jiang, Xiaoting Luo, Yue Duan, Yuchen Bai

  Keywords: rare cancer, TFE3-RCC, Xp11.2 translocation, predict, prognosis

  Published in Aging on January 22, 2024

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• Research PaperVolume 15, Issue 21pp 11831-11844

  RAI2 acts as a tumor suppressor with functional significance in gastric cancer

  Relevance score: 0.00

  Xiaoli Lou, Wei Deng, Lixiong Shuai, Yijing Chen, Mengmeng Xu, Jingze Xu, Yongsheng Zhang, Yongyou Wu, Zhifei Cao

  Keywords: RAI2, gastric cancer, PD-L1, immune infiltration, metastasis

  Published in Aging on October 25, 2023

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• Research PaperVolume 15, Issue 8pp 2999-3020

  Upregulation of RasGRF1 ameliorates spatial cognitive dysfunction in mice after chronic cerebral hypoperfusion

  Relevance score: 0.00

  Li-Jie Yang, Wei Wu, Wan-Rong Jiang, Cheng-Liang Zhu, Zhao-Hui Yao

  Keywords: RasGRF1, cognition impairment, chronic cerebral hypoperfusion, synaptic plasticity, vascular cognitive impairment

  Published in Aging on April 12, 2023

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• Research PaperVolume 15, Issue 6pp 2347-2357

  MiR-320b aberrant expression enhances the radioresistance of human glioma via upregulated expression of ALDH1A3

  Relevance score: 0.00

  Ping Mao, Tuo Wang, Ke Gao, Yi Li, Changwang Du, Maode Wang

  Keywords: radioresistance, miRNA-320b, ALDH1A3, human glioma, miRNAs

  Published in Aging on March 29, 2023

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• Research PaperVolume 15, Issue 5pp 1237-1256

  Senescence-associated exosomes transfer miRNA-induced fibrosis to neighboring cells

  Relevance score: 0.00

  Amy H. Lee, Deepraj Ghosh, Ivy L. Koh, Michelle R. Dawson

  Keywords: radiation-induced senescence, exosomes (EXOs), microRNA (miRNA), transforming growth factor-β (TGF-β), mesenchymal stem cells (MSCs)

  Published in Aging on February 23, 2023

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• ReviewVolume 15, Issue 4pp 905-913

  Cellular senescence: when growth stimulation meets cell cycle arrest

  Relevance score: 0.00

  Mikhail V. Blagosklonny

  Keywords: rapamycin, mTOR, hyperfunction theory of aging, cell volume and enlargement, gerogenic conversion

  Published in Aging on February 19, 2023

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• EditorialVolume 14, Issue 22pp 8884-8885

  Racial and ethnic disparities in Alzheimer’s dementia

  Relevance score: 0.00

  Unhee Lim, Song-Yi Park

  Keywords: Alzheimer’s disease and related dementias, racial and ethnic disparities, population-based cohort studies

  Published in Aging on November 29, 2022

• Research PaperVolume 14, Issue 22pp 9200-9209

  Rapamycin improves the quality and developmental competence of in vitro matured oocytes in aged mice and humans

  Relevance score: 0.00

  Qiyu Yang, Juan Hu, Meng Wang, Na Guo, Liu Yang, Qingsong Xi, Lixia Zhu, Lei Jin

  Keywords: rapamycin, in vitro maturation, oocyte quality, aged population, DNA damage

  Published in Aging on November 26, 2022

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• Priority Research PaperVolume 14, Issue 3pp 1068-1086

  Senescence-associated tumor growth is promoted by 12-Lipoxygenase

  Relevance score: 0.00

  Shilpa Patil, Jessica L. Reedy, Bradley T. Scroggins, Ayla O. White, Seokjoo Kwon, Uma Shankavaram, Alfonso López-Coral, Eun Joo Chung, Deborah E. Citrin

  Keywords: senescence, radiation, senolytic, metastasis, Alox12

  Published in Aging on February 14, 2022

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• EditorialVolume 13, Issue 23pp 24922-24923

  Raman microspectroscopy: sub-cellular chemical imaging of aging

  Relevance score: 0.00

  Lisa Liendl, Markus Schosserer

  Keywords: aging, cellular senescence, Raman microspectroscopy, correlated multimodal imaging, chemical imaging

  Published in Aging on December 13, 2021

• Research PaperVolume 13, Issue 21pp 24071-24085

  LncRNA MIR31HG is induced by tocilizumab and ameliorates rheumatoid arthritis fibroblast-like synoviocyte-mediated inflammation via miR-214-PTEN-AKT signaling pathway

  Relevance score: 0.00

  Liang Cao, Haifeng Jiang, Jing Yang, Jun Mao, Guofeng Wei, Xiangyun Meng, Hongmei Zang

  Keywords: RA-FLS, tocilizumab, MIR31HG, miR-214, PTEN

  Published in Aging on November 9, 2021

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• Research PaperVolume 13, Issue 21pp 24219-24235

  Construction and external validation of a 5-gene random forest model to diagnose non-obstructive azoospermia based on the single-cell RNA sequencing of testicular tissue

  Relevance score: 0.00

  Ranran Zhou, Xianyuan Lv, Tianle Chen, Qi Chen, Hu Tian, Cheng Yang, Wenbin Guo, Cundong Liu

  Keywords: non-obstructive azoospermia, diagnosis, scRNA-seq, random forest, machine learning

  Published in Aging on November 4, 2021

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• Research PaperVolume 13, Issue 20pp 23769-23779

  Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis

  Relevance score: 0.00

  Yiqiong Yang, Jing Wang, Yu Zhang, Xiuxiu Hu, Li Li, Pingsheng Chen

  Keywords: Rab7, MMP-2

  Published in Aging on October 25, 2021

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• EditorialVolume 13, Issue 16pp 19948-19949

  Microbiota-associated molecular genotoxicity

  Relevance score: 0.00

  Irene Maier

  Keywords: radiation, microbiota, bacterial indicator phylotypes, bone loss, microstructure, interleukin-17

  Published in Aging on August 18, 2021

• Research PaperVolume 13, Issue 14pp 18223-18237

  Combination of rapamycin and SAHA enhanced radiosensitization by inducing autophagy and acetylation in NSCLC

  Relevance score: 0.00

  Yong Wang, Fen Liu, Chen Fang, Liyao Xu, Lin Chen, Zeyao Xu, Jiaquan Chen, Wei Peng, Biqi Fu, Yong Li

  Keywords: autophagy, DNA damage, histone deacetylase inhibitor, radiation, rapamycin

  Published in Aging on July 28, 2021

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