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The cover features Figure 6 "Senescent cell elimination drug BPTES improves the skin senescence phenotype of transplanted aged human skin" from Takaya et al.

Volume 14, Issue 22

30 November, 2022
pp 8882—9383

About the Cover

The cover features Figure 6 "Senescent cell elimination drug BPTES improves the skin senescence phenotype of transplanted aged human skin" from Takaya et al.


Explore This Issue

Editorials

Isoaspartate and neurodegeneration

Jijing Wang, Sourav Mukherjee, Roman A. Zubarev,
https://doi.org/10.18632/aging.204420 pp 8882—8883
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Racial and ethnic disparities in Alzheimer’s dementia

Unhee Lim, Song-Yi Park,
https://doi.org/10.18632/aging.204421 pp 8884—8885
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Research Papers

Phosphoglycerate kinase 1 protects against ischemic damage in the gerbil hippocampus

Kyu Ri Hahn, Hyun Jung Kwon, Yeo Sung Yoon, Dae Won Kim, In Koo Hwang,
https://doi.org/10.18632/aging.204343 pp 8886—8899
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Denervation induces mitochondrial decline and exacerbates lysosome dysfunction in middle-aged mice

Matthew Triolo, Debasmita Bhattacharya, David A. Hood,
https://doi.org/10.18632/aging.204365 pp 8900—8913
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Glutaminase inhibitors rejuvenate human skin via clearance of senescent cells: a study using a mouse/human chimeric model

Kento Takaya, Tatsuyuki Ishii, Toru Asou, Kazuo Kishi,
https://doi.org/10.18632/aging.204391 pp 8914—8926
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The potential benefit of metformin to reduce delirium risk and mortality: a retrospective cohort study

Takehiko Yamanashi, Zoe-Ella EM Anderson, Manisha Modukuri, Gloria Chang, Tammy Tran, Pedro S. Marra, Nadia E. Wahba, Kaitlyn J. Crutchley, Eleanor J. Sullivan, Sydney S. Jellison, Katie R. Comp, Cade C. Akers, Alissa A. Meyer, Sangil Lee, Masaaki Iwata, Hyunkeun R. Cho, Eri Shinozaki, Gen Shinozaki,
https://doi.org/10.18632/aging.204393 pp 8927—8943
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JAK2/STAT3 pathway mediates neuroprotective and pro-angiogenic treatment effects of adult human neural stem cells in middle cerebral artery occlusion stroke animal models

Geun-Hyoung Ha, Eun Ji Kim, Jee Soo Park, Ji Eun Kim, Hyun Nam, Je Young Yeon, Sun-Ho Lee, Kyunghoon Lee, Chung Kwon Kim, Kyeung Min Joo,
https://doi.org/10.18632/aging.204410 pp 8944—8969
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Antrodia Camphorata Polysaccharide activates autophagy and regulates NLRP3 degradation to improve liver injury-related inflammatory response

Shuiliang Ruan, Yi Yang, Wenyan Li,
https://doi.org/10.18632/aging.204330 pp 8970—8981
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Protective effect of total saponins of ginseng stems and leaves (GSLS) on chlorpyrifos-induced brain toxicity in mice through the PTEN/PI3K/AKT axis

Hong Wu, Hongyan Pei, Jinze Liu, Jianning Zeng, Silu Liu, Weijia Chen, Zhongmei He, Rui Du,
https://doi.org/10.18632/aging.204374 pp 8982—8999
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NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway

Rui Zhao, Yuzhen Ge, Yongjun Gong, Bo Li, Benli Xiao, Shi Zuo,
https://doi.org/10.18632/aging.204377 pp 9000—9019
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Molecular subtypes identified by pyroptosis-related genes are associated with tumor microenvironment cell infiltration in colon cancer

Yiting Ling, Yinda Wang, Chenxi Cao, Lianzhong Feng, Binzhong Zhang, Senjuan Li,
https://doi.org/10.18632/aging.204379 pp 9020—9036
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Development and validation of a novel model for predicting the survival of bladder cancer based on ferroptosis-related genes

Lianjun Li, Leizuo Zhao, Bin Li, Tengteng Wang, Weiting Kang, Zilian Cui, Dongjian Liu, Da Gu,
https://doi.org/10.18632/aging.204385 pp 9037—9055
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Circadian rhythm-related factors of PER and CRY family genes function as novel therapeutic targets and prognostic biomarkers in lung adenocarcinoma

Chin-Chou Wang, Wei-Hsun Lin, Su-Chi Ku, Wan-Jou Shen, Hoang Dang Khoa Ta, Gangga Anuraga, Fang-Wen Liu, Chiu-Fan Shen, Shu-He Wang, Chia-Chen Yang, Chih-Yang Wang, Wei-Jan Wang,
https://doi.org/10.18632/aging.204386 pp 9056—9089
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A novel risk score model based on four angiogenesis long non-coding RNAs for prognosis evaluation of pancreatic adenocarcinoma

Guangbiao Cao, Yihang Chang, Guang Yang, Yong Jiang, Keqiang Han,
https://doi.org/10.18632/aging.204387 pp 9090—9102
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Exploring the mechanisms underlying the therapeutic effect of the Radix Bupleuri-Rhizoma Cyperi herb pair on hepatocellular carcinoma using multilevel data integration and molecular docking

Luzhi Qing, Botao Pan, Yanjun He, Yu Liu, Minhong Zhao, Bo Niu, Xiuan Gao,
https://doi.org/10.18632/aging.204388 pp 9103—9127
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Prognostic value and immunological role of FOXM1 in human solid tumors

Guohua Wei, Xin Yang, Huangzhou Lu, Lan Zhang, Yong Wei, Hai Li, Mingxia Zhu, Xin Zhou,
https://doi.org/10.18632/aging.204394 pp 9128—9148
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LINC00629, a KLF10-responsive lncRNA, promotes the anticancer effects of apigenin by decreasing Mcl1 stability in oral squamous cell carcinoma

Chun Shi, Changhong Ma, Chunmei Ren, Na Li, Xiaotong Liu, Yahan Zhang, Yulong Wang, Xiaodong Li, Peng Lv, Chuanchun Han, Xiaojie Li,
https://doi.org/10.18632/aging.204396 pp 9149—9166
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Minichromosome maintenance gene family: potential therapeutic targets and prognostic biomarkers for lung squamous cell carcinoma

Xuejie Yang, Chunrong Wang, Hui Nie, Jianhua Zhou, Xiaoyun He, Chunlin Ou,
https://doi.org/10.18632/aging.204399 pp 9167—9185
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Restraint stress of female mice during oocyte development facilitates oocyte postovulatory aging

Ren-Ren Chen, Jia Wang, Min Zhang, Qiao-Qiao Kong, Guang-Yi Sun, Chun-Hui Jin, Ming-Jiu Luo, Jing-He Tan,
https://doi.org/10.18632/aging.204400 pp 9186—9199
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Rapamycin improves the quality and developmental competence of in vitro matured oocytes in aged mice and humans

Qiyu Yang, Juan Hu, Meng Wang, Na Guo, Liu Yang, Qingsong Xi, Lixia Zhu, Lei Jin,
https://doi.org/10.18632/aging.204401 pp 9200—9209
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Resident intruder paradigm-induced PMDD rat model of premenstrual irritability: behavioral phenotypes, drug intervention, and biomarkers

Mingzhou Gao, Hao Zhang, Zhan Gao, Ya Sun, Guanghao Xu, Fengqin Wei, Jieqiong Wang, Dongmei Gao,
https://doi.org/10.18632/aging.204402 pp 9210—9220
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Comprehensive analysis of the expression profile and clinical implications of regulator of chromosome condensation 2 in pan-cancers

Xuanxuan Li, Kuo Kang, Yuanhao Peng, Lin Shen, Liangfang Shen, Yangying Zhou,
https://doi.org/10.18632/aging.204403 pp 9221—9242
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System analysis based on the ER stress-related genes identifies WFS1 as a novel therapy target for colon cancer

Xianguang Yang, Chaoyang Zhang, Cheng Yan, Liukai Ma, Jiahao Ma, Xiaoke Meng,
https://doi.org/10.18632/aging.204404 pp 9243—9263
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CD229 interacts with RASAL3 to activate RAS/ERK pathway in multiple myeloma proliferation

Zigen Lin, Xiaozhu Tang, Yuhao Cao, Lijin Yang, Mingmei Jiang, Xinying Li, Jie Min, Bing Chen, Ye Yang, Chunyan Gu,
https://doi.org/10.18632/aging.204405 pp 9264—9279
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The circRNA expression profile of colorectal inflammatory cancer transformation revealed potential predictive biomarkers

Lu Lu, Yujing Liu, Guangtao Zhang, Yangxian Xu, Dan Hu, Guang Ji, Hanchen Xu,
https://doi.org/10.18632/aging.204406 pp 9280—9299
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The roles of CPSF6 in proliferation, apoptosis and tumorigenicity of lung adenocarcinoma

Yukun Zu, Dao Wang, Wei Ping, Wei Sun,
https://doi.org/10.18632/aging.204407 pp 9300—9316
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High SURF4 expression is associated with poor prognosis of breast cancer

Jingtong Zhai, Jiashu Han, Cong Li, Fengzhu Guo, Fei Ma, Binghe Xu,
https://doi.org/10.18632/aging.204409 pp 9317—9337
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Review

Organotypic cultures as aging associated disease models

Martina M. Sanchez, Isabella A. Bagdasarian, William Darch, Joshua T. Morgan,
https://doi.org/10.18632/aging.204361 pp 9338—9383
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Volume 14, Issue 22  
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