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Page: 12345 of 5

• Research PaperVolume 15, Issue 9pp 3381-3393

  PI3K-Akt signaling pathway based on network pharmacology for the anti-Alzheimer’s disease effect of licorice stem flavonoids

  Relevance score: 0.00

  Hongyan Pei, Lei He, Meiling Shi, Xiangjuan Guo, Weijia Chen, Jianming Li, Zhongmei He, Rui Du

  Keywords: network pharmacology, Alzheimer’s disease, licorice stem flavonoids, PI3K-Akt signalling pathway

  Published in Aging on February 22, 2023

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• Research PaperVolume 15, Issue 20pp 11162-11183

  Machine learning developed a PI3K/Akt pathway-related signature for predicting prognosis and drug sensitivity in ovarian cancer

  Relevance score: 0.00

  Xiaofang Han, Liu Yang, Hui Tian, Yuanyuan Ji

  Keywords: immunotherapy, prognostic signature, ovarian cancer, machine learning, PI3K/Akt pathway

  Published in Aging on October 17, 2023

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• Research PaperVolume 11, Issue 22pp 10697-10710

  MAP2K4 interacts with Vimentin to activate the PI3K/AKT pathway and promotes breast cancer pathogenesis

  Relevance score: 0.00

  Shu Liu, Juan Huang, Yewei Zhang, Yiyi Liu, Shi Zuo, Rong Li

  Keywords: MAP2K4, breast cancer, PI3K/AKT pathway, Vimentin

  Published in Aging on November 25, 2019

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• Research PaperVolume 16, Issue 4pp 3773-3789

  Yangyinghuoxue decoction exerts a treatment effect on hepatic fibrosis by PI3K/AKT pathway in rat model: based on the network pharmacology and molecular docking

  Relevance score: 0.00

  Yan-Ming Bai, Shuang Liang, Bo Zhou

  Keywords: Yangyinghuoxue decoction (YYHXD), hepatic fibrosis (HF), network pharmacology, PI3K-Akt signaling pathway, molecular docking

  Published in Aging on February 15, 2024

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• Research PaperVolume 11, Issue 20pp 8845-8859

  COL6A6 interacted with P4HA3 to suppress the growth and metastasis of pituitary adenoma via blocking PI3K-Akt pathway

  Relevance score: 0.00

  Ruiqing Long, Zhuohui Liu, Jinghui Li, Hualin Yu

  Keywords: pituitary adenoma, COL6A6, P4HA3, PI3K-Akt pathway, invasion

  Published in Aging on October 17, 2019

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• Research PaperVolume 13, Issue 5pp 6945-6956

  Silencing of miR-483-5p alleviates postmenopausal osteoporosis by targeting SATB2 and PI3K/AKT pathway

  Relevance score: 0.00

  Fujiang Zhao, Yier Xu, Yulong Ouyang, Zhexu Wen, Guihao Zheng, Ting Wan, Guicai Sun

  Keywords: postmenopausal osteoporosis, miR-483-5p, SATB2, PI3K/AKT pathway

  Published in Aging on February 17, 2021

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• Research PaperVolume 11, Issue 10pp 3376-3391

  MicroRNA-335/ID4 dysregulation predicts clinical outcome and facilitates leukemogenesis by activating PI3K/Akt signaling pathway in acute myeloid leukemia

  Relevance score: 0.00

  Jing-dong Zhou, Xi-xi Li, Ting-juan Zhang, Zi-jun Xu, Zhi-hui Zhang, Yu Gu, Xiang-mei Wen, Wei Zhang, Run-bi Ji, Zhao-qun Deng, Jiang Lin, Jun Qian

  Keywords: MiR-335, ID4, acute myeloid leukemia, prognosis, PI3K/Akt pathway

  Published in Aging on May 30, 2019

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• Research PaperVolume 16, Issue 4pp 3955-3972

  Protective effects of triptolide against oxidative stress in retinal pigment epithelium cells via the PI3K/AKT/Nrf2 pathway: a network pharmacological method and experimental validation

  Relevance score: 0.00

  Fuying Pan, Qinxin Shu, Hao Xie, Long Zhao, Ping Wu, Yong Du, Jing Lu, Yuxia He, Xing Wang, Hui Peng

  Keywords: triptolide, oxidative stress, PI3K/Akt/Nrf2 pathway, network pharmacological analysis

  Published in Aging on February 21, 2024

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• Research PaperVolume 13, Issue 19pp 22843-22855

  Allicin protects against myocardial I/R by accelerating angiogenesis via the miR-19a-3p/PI3K/AKT axis

  Relevance score: 0.00

  Mengru Liu, Peng Yang, Dongliang Fu, Tong Gao, Xinyi Deng, Mingjing Shao, Jiangquan Liao, Hong Jiang, Xianlun Li

  Keywords: myocardial I/R, miR-19a-3p, PI3K/AKT pathway, angiogenesis, Allicin

  Published in Aging on October 4, 2021

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• Research PaperVolume 13, Issue 16pp 20179-20191

  Long non-coding RNA ABHD11-AS1 promotes colorectal cancer progression and invasion through targeting the integrin subunit alpha 5/focal adhesion kinase/phosphoinositide 3 kinase/Akt signaling pathway

  Relevance score: 0.00

  Jia Luo, Yigui Jiang, Lianhui Wu, Dexiang Zhuo, Shengjun Zhang, Xiang Jiang, Yingming Sun, Yue Huang

  Keywords: colorectal cancer, lncRNA-ABHD11-AS1, PI3K/Akt pathway, oncogene profile

  Published in Aging on August 10, 2021

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• Research PaperVolume 13, Issue 15pp 19643-19656

  The protective effect of allicin on myocardial ischemia-reperfusion by inhibition of Ca²⁺ overload-induced cardiomyocyte apoptosis via the PI3K/GRK2/PLC-γ/IP3R signaling pathway

  Relevance score: 0.00

  Tong Gao, Peng Yang, Dongliang Fu, Mengru Liu, Xinyi Deng, Mingjing Shao, Jiangquan Liao, Hong Jiang, Xianlun Li

  Keywords: allicin, apoptosis, PI3K/Akt pathway, myocardial ischemia/reperfusion, gene expression profiling, calcium signaling pathway, GRK2, GPCR

  Published in Aging on August 3, 2021

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• Research PaperVolume 12, Issue 10pp 9915-9934

  ZNF139/circZNF139 promotes cell proliferation, migration and invasion via activation of PI3K/AKT pathway in bladder cancer

  Relevance score: 0.00

  Jie Yao, Kaiyu Qian, Chen Chen, Xiaoping Liu, Donghu Yu, Xin Yan, Tongzu Liu, Sheng Li

  Keywords: circular RNA, ZNF139, bladder cancer, PI3K/AKT signaling pathway, bioinformatics

  Published in Aging on May 26, 2020

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• Research PaperVolume 13, Issue 2pp 2251-2263

  β-Arrestin-2 attenuates hepatic ischemia-reperfusion injury by activating PI3K/Akt signaling

  Relevance score: 0.00

  Xiaolong Chen, Junbin Zhang, Long Xia, Li Wang, Hui Li, Huilin Liu, Jing Zhou, Zhiying Feng, Hai Jin, JianXu Yang, Yang Yang, Bin Wu, Lei Zhang, Guihua Chen, Genshu Wang

  Keywords: hepatic ischemia-reperfusion injury, β-Arrestin-2, PI3K/Akt signaling pathway, liver transplantation, hepatic surgery

  Published in Aging on December 11, 2020

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• Research PaperVolume 16, Issue 9pp 7979-7999

  Mechanistic exploration and experimental validation of the Xiaochaihu decoction for the treatment of breast cancer by network pharmacology

  Relevance score: 0.00

  Qinglong Liu, Zehua Luo, Mei Sun, Wenjun Li, Songqing Liu

  Keywords: Xiaochaihu decoction, breast cancer, network pharmacology, PI3K/Akt pathway, Q Exactive Orbitrap LC-MS/MS

  Published in Aging on May 13, 2024

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• Research PaperVolume 13, Issue 15pp 19375-19396

  THBS4/integrin α2 axis mediates BM-MSCs to promote angiogenesis in gastric cancer associated with chronic Helicobacter pylori infection

  Relevance score: 0.00

  LingNan He, WeiJun Wang, HuiYing Shi, Chen Jiang, HaiLing Yao, YuRui Zhang, Wei Qian, Rong Lin

  Keywords: bone marrow-derived mesenchymal stem cells (BM-MSCs), gastric cancer (GC), tumor angiogenesis, THBS4/Integrin α2 axis, PI3K/AKT pathway

  Published in Aging on August 14, 2021

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• Research PaperVolume 13, Issue 4pp 5607-5620

  Calreticulin: a potential diagnostic and therapeutic biomarker in gallbladder cancer

  Relevance score: 0.00

  Jianwen Ye, Lei Qi, Zhicheng Du, Long Yu, Kunlun Chen, Renfeng Li, Ruo Feng, Wenlong Zhai

  Keywords: gallbladder cancer, calreticulin, biomarker, PI3K/Akt pathway

  Published in Aging on February 11, 2021

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• Research Paper

  Chronic stress promotes premature ovarian failure in mice by inhibiting ovarian granulosa cell autophagy through PI3K-AKTmTOR pathway

  Relevance score: 0.00

  Zhibin Zhao, Xuefei Yuan, Baohua Zhao, Kai He

  Keywords: PI3K-AKT-mTOR pathway, premature ovarian failure (POF), ovarian granulosa cells (OGCs), chronic stress

  Published in Aging on October 8, 2024

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• Research PaperVolume 13, Issue 10pp 13626-13643

  E2F2 inhibition induces autophagy via the PI3K/Akt/mTOR pathway in gastric cancer

  Relevance score: 0.00

  Hui Li, Shufen Zhao, Liwei Shen, Peige Wang, Shihai Liu, Yingji Ma, Zhiwei Liang, Gongjun Wang, Jing Lv, Wensheng Qiu

  Keywords: gastric cancer, E2F2, autophagy, metastasis, PI3K/Akt/mTOR pathway

  Published in Aging on April 21, 2021

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• Research PaperVolume 16, Issue 5pp 4789-4810

  SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization

  Relevance score: 0.00

  Kai Feng, Ya Di, Meng Han, Weitao Yan, Yimin Wang

  Keywords: breast cancer cells, PI3K/AKT signaling pathway, macrophage polarization, epithelial mesenchymal transition, SORBS1

  Published in Aging on March 6, 2024

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• Research PaperVolume 15, Issue 8pp 2920-2936

  ESM1 promotes angiogenesis in colorectal cancer by activating PI3K/Akt/mTOR pathway, thus accelerating tumor progression

  Relevance score: 0.00

  Liqun Yang, Zhigang Dong, Shuyu Li, Tieliang Chen

  Keywords: ESM1, PI3K/Akt/mTOR pathway, CRC, angiogenesis

  Published in Aging on March 7, 2023

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