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Page: 12345 of 5

• Research PaperVolume 16, Issue 5pp 4789-4810

  SORBS1 inhibits epithelial to mesenchymal transition (EMT) of breast cancer cells by regulating PI3K/AKT signaling and macrophage phenotypic polarization

  Relevance score: 0.00

  Kai Feng, Ya Di, Meng Han, Weitao Yan, Yimin Wang

  Keywords: breast cancer cells, PI3K/AKT signaling pathway, macrophage polarization, epithelial mesenchymal transition, SORBS1

  Published in Aging on March 6, 2024

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• Research PaperVolume 16, Issue 4pp 3773-3789

  Yangyinghuoxue decoction exerts a treatment effect on hepatic fibrosis by PI3K/AKT pathway in rat model: based on the network pharmacology and molecular docking

  Relevance score: 0.00

  Yan-Ming Bai, Shuang Liang, Bo Zhou

  Keywords: Yangyinghuoxue decoction (YYHXD), hepatic fibrosis (HF), network pharmacology, PI3K-Akt signaling pathway, molecular docking

  Published in Aging on February 15, 2024

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• Research PaperVolume 13, Issue 11pp 15078-15099

  Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation

  Relevance score: 0.00

  Peng Zeng, Xiao-Ming Wang, Chao-Yuan Ye, Hong-Fei Su, Ying-Yan Fang, Teng Zhang, Qing Tian

  Keywords: emodin, depression, systems pharmacology, neuroinflammation, PI3K-Akt signaling pathway

  Published in Aging on May 29, 2021

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• Research PaperVolume 12, Issue 24pp 25090-25100

  miR-100-3p inhibits the adipogenic differentiation of hMSCs by targeting PIK3R1 via the PI3K/AKT signaling pathway

  Relevance score: 0.00

  Tao Wang, Donghuo Zhong, Zhongjun Qin, Shan He, Ying Gong, Weidong Li, Xingnuan Li

  Keywords: microRNA-100-3p, hMSCs, adipogenic differentiation, PIK3R1, PI3K/AKT signaling pathway

  Published in Aging on November 20, 2020

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• Research PaperVolume 12, Issue 9pp 8029-8048

  Artesunate promotes the proliferation of neural stem/progenitor cells and alleviates Ischemia-reperfusion Injury through PI3K/Akt/FOXO-3a/p27^kip1 signaling pathway

  Relevance score: 0.00

  Kaiyuan Zhang, Yang Yang, Hongfei Ge, Ju Wang, Xuezhu Chen, Xuejiao Lei, Jun Zhong, Chao Zhang, Jishu Xian, Yongling Lu, Liang Tan, Hua Feng

  Keywords: artesunate, neural stem/progenitor cells, OGD, stroke, PI3K/Akt/FOXO-3a/p27 signaling pathway ^kip1

  Published in Aging on May 7, 2020

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• Research PaperVolume 13, Issue 2pp 2251-2263

  β-Arrestin-2 attenuates hepatic ischemia-reperfusion injury by activating PI3K/Akt signaling

  Relevance score: 0.00

  Xiaolong Chen, Junbin Zhang, Long Xia, Li Wang, Hui Li, Huilin Liu, Jing Zhou, Zhiying Feng, Hai Jin, JianXu Yang, Yang Yang, Bin Wu, Lei Zhang, Guihua Chen, Genshu Wang

  Keywords: hepatic ischemia-reperfusion injury, β-Arrestin-2, PI3K/Akt signaling pathway, liver transplantation, hepatic surgery

  Published in Aging on December 11, 2020

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• Research PaperVolume 12, Issue 10pp 9915-9934

  ZNF139/circZNF139 promotes cell proliferation, migration and invasion via activation of PI3K/AKT pathway in bladder cancer

  Relevance score: 0.00

  Jie Yao, Kaiyu Qian, Chen Chen, Xiaoping Liu, Donghu Yu, Xin Yan, Tongzu Liu, Sheng Li

  Keywords: circular RNA, ZNF139, bladder cancer, PI3K/AKT signaling pathway, bioinformatics

  Published in Aging on May 26, 2020

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• Research PaperVolume 15, Issue 4pp 1052-1073

  TIPE2 acts as a tumor suppressor and correlates with tumor microenvironment immunity in epithelial ovarian cancer

  Relevance score: 0.00

  Shuai Xu, Xiaolin Gao, Jianqing Qiu, Fanzhen Hong, Fufeng Gao, Xia Wang, Shiqian Zhang

  Keywords: epithelial ovarian cancer, TIPE2, progression, PI3K/Akt signaling pathway, tumor microenvironment

  Published in Aging on February 17, 2023

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• Research PaperVolume 13, Issue 21pp 24290-24312

  Decoding the chemical composition and pharmacological mechanisms of Jiedu Tongluo Tiaogan Formula using high-performance liquid chromatography coupled with network pharmacology-based investigation

  Relevance score: 0.00

  Qi Zhang, Chunli Piao, Wenqi Jin, De Jin, Han Wang, Cheng Tang, Xiaohua Zhao, Naiwen Zhang, Shengnan Gao, Fengmei Lian

  Keywords: Jiedu Tongluo Tiaogan Formula, type 2 diabetes mellitus, network pharmacology, PI3K/Akt signaling pathway, traditional Chinese medicine

  Published in Aging on November 5, 2021

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• Research PaperVolume 16, Issue 13pp 10799-10812

  G-CSF promotes the development of hepatocellular carcinoma by activating the PI3K/AKT/mTOR pathway in TAM

  Relevance score: 0.00

  Heng Cao, Shunxiang Wang

  Keywords: hepatocellular carcinoma, granulocyte colony-stimulating factor, PI3K/AKT/mTOR signaling pathway, tumor-associated macrophages

  Published in Aging on July 1, 2024

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• Research PaperVolume 14, Issue 9pp 3887-3909

  Ox-LDL-mediated ILF3 overexpression in gastric cancer progression by activating the PI3K/AKT/mTOR signaling pathway

  Relevance score: 0.00

  Danping Sun, Mingxiang Zhang, Meng Wei, Zhaoyang Wang, Wen Qiao, Peng Liu, Xin Zhong, Yize Liang, Yuanyuan Chen, Yadi Huang, Wenbin Yu

  Keywords: gastric cancer, dyslipidemia, interleukin-enhancer binding factor 3 (ILF3), ox-LDL, PI3K/AKT/mTOR signaling pathway, biomarkers

  Published in Aging on May 4, 2022

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• Research Paper

  Ginsenoside Rh4 reverses ABCB1-induced doxorubicin resistance via the PI3Kδ/AKT axis in osteosarcoma

  Relevance score: 0.00

  Tianqi Xia, Xinyan Shen, Huidong Chen, Yan Zhang, Yi Xu, Shen Zan, Daliu Min, Yonggang Wang

  Keywords: osteosarcoma, multidrug resistance, ginsenoside Rh4, ABCB1, PI3Kδ/AKT signaling pathway

  Published in Aging on July 15, 2024

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• Research PaperVolume 14, Issue 3pp 1253-1264

  Puerarin inhibits FUNDC1-mediated mitochondrial autophagy and CSE-induced apoptosis of human bronchial epithelial cells by activating the PI3K/AKT/mTOR signaling pathway

  Relevance score: 0.00

  Li Wang, Weizhou Jiang, Jing Wang, Yuanyuan Xie, Weisi Wang

  Keywords: chronic obstructive pulmonary disease, puerarin, mitochondrial autophagy, FUNDC1, PI3K/AKT/mTOR signaling pathway

  Published in Aging on February 8, 2022

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• Research PaperVolume 16, Issue 8pp 6937-6953

  High-dose Vitamin C injection ameliorates against sepsis-induced myocardial injury by anti-apoptosis, anti-inflammatory and pro-autophagy through regulating MAPK, NF-κB and PI3K/AKT/mTOR signaling pathways in rats

  Relevance score: 0.00

  Ya-Nan Cui, Na Tian, Yan-Hai Luo, Ji-Jun Zhao, Cheng-Fei Bi, Yi Gou, Jia Liu, Ke Feng, Jun-Fei Zhang

  Keywords: High-dose Vitamin C, sepsis-induced myocardial injury, apoptosis, autophagy, inflammatory, MAPK, NF-κB and PI3K/AKT/mTOR signaling pathways

  Published in Aging on April 19, 2024

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• Research PaperVolume 13, Issue 22pp 24829-24849

  Bone morphogenetic protein 9 enhances osteogenic and angiogenic responses of human amniotic mesenchymal stem cells cocultured with umbilical vein endothelial cells through the PI3K/AKT/m-TOR signaling pathway

  Relevance score: 0.00

  Ziming Liu, Yuwan Li, Jianye Yang, Jiaxing Huang, Changqi Luo, Jun Zhang, Wenqiang Yan, Yingfang Ao

  Keywords: bone morphogenetic protein 9, human amniotic mesenchymal stem cells, umbilical vein endothelial cells, PI3K/AKT/m-TOR signaling pathway

  Published in Aging on November 27, 2021

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• Research PaperVolume 12, Issue 18pp 18127-18136

  GHR knockdown enhances the sensitivity of HCC cells to sorafenib

  Relevance score: 0.00

  Shuang Gao, Qianwen Ni, Xiuli Wu, Tieliu Cao

  Keywords: hepatocellular carcinoma, sorafenib, GHR, resistance, PI3K/AKT/ERK1/2 signaling pathway

  Published in Aging on September 24, 2020

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• Research PaperVolume 13, Issue 15pp 19643-19656

  The protective effect of allicin on myocardial ischemia-reperfusion by inhibition of Ca²⁺ overload-induced cardiomyocyte apoptosis via the PI3K/GRK2/PLC-γ/IP3R signaling pathway

  Relevance score: 0.00

  Tong Gao, Peng Yang, Dongliang Fu, Mengru Liu, Xinyi Deng, Mingjing Shao, Jiangquan Liao, Hong Jiang, Xianlun Li

  Keywords: allicin, apoptosis, PI3K/Akt pathway, myocardial ischemia/reperfusion, gene expression profiling, calcium signaling pathway, GRK2, GPCR

  Published in Aging on August 3, 2021

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• Research PaperVolume 15, Issue 20pp 11654-11671

  PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway

  Relevance score: 0.00

  Jiacheng Zhong, Chao Yuan, Lin Liu, Yang Du, Yumin Hui, Zhiyuan Chen, Changhui Diao, Rui Yang, Guiyong Liu, Xiuheng Liu

  Keywords: PCMT1, prostate cancer, PI3K/AKT/GSK-3β signaling pathway

  Published in Aging on October 27, 2023

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• Research PaperVolume 12, Issue 13pp 13115-13127

  ROR2 knockdown suppresses breast cancer growth through PI3K/ATK signaling

  Relevance score: 0.00

  Muhong Guo, Ge Ma, Xiaolan Zhang, Weiwei Tang, Junfeng Shi, Qian Wang, Ye Cheng, Bin Zhang, Jin Xu

  Keywords: ROR2, breast cancer cell, proliferation, apoptosis, PI3K/AKT signaling

  Published in Aging on July 2, 2020

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• Research PaperVolume 15, Issue 19pp 10540-10548

  Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling

  Relevance score: 0.00

  Jianhua Wang, Hongyan Zhan, Mingming Wang, Hua Song, Jianhua Sun, Gang Zhao

  Keywords: pressure ulcer, EPCs, SHH signaling, angiogenesis, PI3K/AKT/eNOS signaling

  Published in Aging on October 9, 2023

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