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• Research PaperVolume 17, Issue 11pp 2717-2743

  Methylglyoxal-induced glycation stress promotes aortic stiffening: putative mechanistic roles of oxidative stress and cellular senescence

  Relevance score: 0.00

  Parminder Singh, Ravinandan Venkatasubramanian, Sophia A. Mahoney, Mary A. Darrah, Katelyn R. Ludwig, Alice Zhang, Kiyomi Kaneshiro, Lizbeth Enriquez Najera, Lauren Wimer, Muniesh M. Shanmugam, Edgard Morazan, James J. Galligan, Marrisa N. Trujillo, Richmond Sarpong, Douglas R. Seals, Pankaj Kapahi, Zachary S. Clayton

  Keywords: glycation stress, methylglyoxal, pulse wave velocity, gly-low, vascular dysfunction

  Published in Aging on November 14, 2025

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• Research PerspectiveVolume 17, Issue 5pp 1082-1090

  Methylation clocks for evaluation of anti-aging interventions

  Relevance score: 0.00

  Josh Mitteldorf

  Keywords: methylation, stochastic, entropy, programmed aging, aging clock, epigenetic clock

  Published in Aging on May 5, 2025

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• Research PaperVolume 17, Issue 2pp 588-606

  Pan-cancer analysis of Methyltransferase-like 16 (METTL16) and validated in colorectal cancer

  Relevance score: 0.00

  Ling Liu, Siying Wang, Xuyu Chen, Qian Luo, Zhaoxia Wang, Juan Li

  Keywords: METTL16, pan-cancer, biomarker, colorectal cancer, tumorigenesis

  Published in Aging on February 27, 2025

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• Research PaperVolume 16, Issue 19pp 12893-12908

  Identification of metabolomic changes and potential therapeutic targets during ovarian aging

  Relevance score: 0.00

  Bo Sun, Lu Li, Xiaoli Chen, Yingpu Sun

  Keywords: metabolomics, ovarian aging, GABA, succinic acid, ART

  Published in Aging on October 9, 2024

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• EditorialVolume 16, Issue 16pp 11773-11775

  Cardiac metabolism in the elderly: effects and consequences

  Relevance score: 0.00

  Mohammad Kasim Fatmi, Nadiyeh Rouhi, Lucian Lozonschi, Ji Li

  Keywords: metabolism, aging, heart failure, Pdk4

  Published in Aging on August 19, 2024

• Research PaperVolume 16, Issue 12pp 10546-10562

  NAT1 inhibits liver metastasis of colorectal cancer by regulating EMT and glycolysis

  Relevance score: 0.00

  Wang Gu, Chen Li, Tingting Shen, Li Tong, Wenkang Yuan, Xiaofei Zheng, Tianqi Wang, Siyu Wang, Benshuai Zhu, Chong Zhang, Chao Zhang

  Keywords: NAT1, colorectal cancer (CRC), liver metastasis, epithelial-mesenchymal transition (EMT), glycolysis, VEGF

  Published in Aging on June 24, 2024

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• Research PaperVolume 16, Issue 11pp 9584-9598

  The association between diabetes mellitus and prostate cancer: a meta-analysis and Mendelian randomization

  Relevance score: 0.00

  Gui-Chen Ye, Yu-Xuan Yang, Kuang-Di Luo, Shao-Gang Wang, Qi-Dong Xia

  Keywords: meta-analysis, diabetes mellitus, prostate cancer, Mendelian randomization, obesity

  Published in Aging on June 4, 2024

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• Research PaperVolume 16, Issue 10pp 8772-8809

  Prediction of prognosis and immunotherapy efficacy based on metabolic landscape in lung adenocarcinoma by bulk, single-cell RNA sequencing and Mendelian randomization analyses

  Relevance score: 0.00

  Yong Liu, Xiangwei Zhang, Zhaofei Pang, Yadong Wang, Haotian Zheng, Guanghui Wang, Kai Wang, Jiajun Du

  Keywords: metabolic reprogramming, prognosis, tumor microenvironment, immunotherapy, lung adenocarcinoma

  Published in Aging on May 20, 2024

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• ReviewVolume 16, Issue 8pp 7487-7504

  HCMMD: systematic evaluation of metabolites in body fluids as liquid biopsy biomarker for human cancers

  Relevance score: 0.00

  Xun Dong, Yaoyao Qu, Tongtong Sheng, Yuanming Fan, Silu Chen, Qinbo Yuan, Gaoxiang Ma, Yuqiu Ge

  Keywords: cancer, liquid biopsy, metabolites, diagnostic biomarker, database

  Published in Aging on April 26, 2024

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• Research PaperVolume 16, Issue 9pp 7668-7682

  Causal association of metformin treatment with diverse cardiovascular diseases: a Mendelian randomization analysis

  Relevance score: 0.00

  Kaiyuan Li, Peng Liu, Jun Ye, Miao Liu, Li Zhu

  Keywords: metformin, cardiovascular disease, diabetes, causal association, Mendelian randomization study

  Published in Aging on April 26, 2024

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• Research PaperVolume 16, Issue 8pp 7217-7248

  Hepatocyte-specific METTL3 ablation by Alb-iCre mice (GPT), but not by Alb-Cre mice (JAX), resulted in acute liver failure (ALF) and postnatal lethality

  Relevance score: 0.00

  Shihao Huang, Yingchun Li, Bingjie Wang, Zhihao Zhou, Yonglong Li, Lingjun Shen, Jinge Cong, Liuxin Han, Xudong Xiang, Jiawei Xia, Danhua He, Zhanlin Zhao, Ying Zhou, Qiwen Li, Guanqi Dai, Hanzhang Shen, Taoyan Lin, Aibing Wu, Junshuang Jia, Dong Xiao, Jing Li, Wentao Zhao, Xiaolin Lin

  Keywords: METTL3, Alb-iCre mice (GPT), Alb-Cre mice (JAX), acute liver failure (ALF), postnatal lethality

  Published in Aging on April 22, 2024

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• Research PaperVolume 16, Issue 7pp 6364-6383

  Metabolic score for insulin resistance predicts major adverse cardiovascular event in premature coronary artery disease

  Relevance score: 0.00

  Dachuan Guo, Chong Zhang, Mingyan Zhang, Zhenguo Wu, Xiaoyu Liu, Yerui Zhang, Li Liu, Meili Sun, Jianmin Yang

  Keywords: premature coronary artery disease, insulin resistance, major adverse cardiovascular events, prognosis, metabolic score for insulin resistance

  Published in Aging on April 1, 2024

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• Research PaperVolume 16, Issue 6pp 4948-4964

  Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging

  Relevance score: 0.00

  Sher Bahadur Poudel, Dorra Frikha-Benayed, Ryan R. Ruff, Gozde Yildirim, Manisha Dixit, Ron Korstanje, Laura Robinson, Richard A. Miller, David E. Harrison, John R. Strong, Mitchell B. Schaffler, Shoshana Yakar

  Keywords: methylene blue, mitoquinone, bone, micro-CT, antioxidants

  Published in Aging on March 25, 2024

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• Research PaperVolume 16, Issue 3pp 2638-2656

  Serum metabolome and gut microbiome alterations are associated with low handgrip strength in older adults

  Relevance score: 0.00

  Yan Guo, Qin Wang, Yifan Lv, Fan Xia, Xin Chen, Yan Mao, Xiaodong Wang, Guoxian Ding, Jing Yu

  Keywords: metabolomics, metabolites, gut microbiota, omics integration, handgrip strength

  Published in Aging on February 1, 2024

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• Research PaperVolume 16, Issue 1pp 191-206

  Manganese and IL-12 treatment alters the ovarian tumor microenvironment

  Relevance score: 0.00

  Yan Xu, Xin Huang, Xiao-Cui Nie, Yan-Song Liu, Yang Zhou, Ju-Min Niu

  Keywords: metal immunotherapy, Mn²⁺, IL-12, macrophage, ovarian tumor

  Published in Aging on January 3, 2024

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• Research PaperVolume 15, Issue 24pp 14720-14732

  Meteorin-like protein elevation post-exercise improved vascular inflammation among coronary artery disease patients by downregulating NLRP3 inflammasome activity

  Relevance score: 0.00

  Jingjin Liu, Liwei Diao, Weiyi Xia, Xiaoyi Zeng, Wen Li, Jieru Zou, Tiansheng Liu, Xinli Pang, Yongshun Wang

  Keywords: coronary artery disease, meteorin-like protein, moderate intensity continuous training exercises, NLR family pyrin domain containing 3 inflammasome, inflammatory cytokines

  Published in Aging on December 4, 2023

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• Research PaperVolume 15, Issue 21pp 11831-11844

  RAI2 acts as a tumor suppressor with functional significance in gastric cancer

  Relevance score: 0.00

  Xiaoli Lou, Wei Deng, Lixiong Shuai, Yijing Chen, Mengmeng Xu, Jingze Xu, Yongsheng Zhang, Yongyou Wu, Zhifei Cao

  Keywords: RAI2, gastric cancer, PD-L1, immune infiltration, metastasis

  Published in Aging on October 25, 2023

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• Research PaperVolume 15, Issue 15pp 7551-7564

  Metastasis-related long non-coding RNAs AL359220.1, SH3BP5-AS1 and ZF-AS1 are significant for prognostic assessment of lung adenocarcinoma

  Relevance score: 0.00

  Jianjun Tan, Weilin Mao, Shuzi Long, Tao Zhang

  Keywords: lung adenocarcinoma, metastasis, long non-coding RNA, risk model

  Published in Aging on August 10, 2023

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• Research PaperVolume 15, Issue 14pp 7219-7236

  Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma

  Relevance score: 0.00

  Sen Qin, Lei Li, Da Liu

  Keywords: metastasis-related gene, immunity, osteosarcoma, immunotherapy, drug screening

  Published in Aging on July 25, 2023

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• Research PaperVolume 15, Issue 14pp 6690-6709

  Parallel shift of DNA methylation and gene expression toward the mean in mouse spleen with aging

  Relevance score: 0.00

  Sangkyun Jeong, Sunwha Cho, Seung Kyoung Yang, Soo A. Oh, Yong-Kook Kang

  Keywords: methylation shift/drift, hypermethylation, hypomethylation, SiNG-PCR-seq, RRBS

  Published in Aging on July 25, 2023

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