Volume 16, Issue 1

January 15, 2024pp 1—984

About the Cover

The cover features Figure 4 "Resveratrol increases in vitro rhythmic gene mRNA expression of core clock components in human adipose-derived progenitor cells (APCs) from older participants" from Kapar et al.

Research Papers

Effects of resveratrol on in vitro circadian clock gene expression in young and older human adipose-derived progenitor cells

Sophie G.C. Kapar, Maria F. Pino, Fanchao Yi, Miguel A. Gutierrez-Monreal, Karyn A. Esser, Lauren M. Sparks, Melissa L. Erickson

https://doi.org/10.18632/aging.205292pp 1—14

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Composite dietary antioxidant index associated with delayed biological aging: a population-based study

Huiqin He, Xin Chen, Yiming Ding, Xiaoli Chen, Xingkang He

https://doi.org/10.18632/aging.205232pp 15—27

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High expression of integrin-binding sialoprotein (IBSP) is associated with poor prognosis of osteosarcoma

Yihang Ma, Bing Chen, Boyin Zhang, Chao Zhang, Qingsan Zhu, Xu Wang, Zhengang Liu, Haochuan Liu

https://doi.org/10.18632/aging.205235pp 28—42

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An endoplasmic reticulum stress-related signature featuring ASNS for predicting prognosis and immune landscape in prostate cancer

Zhenyu Wu, Zhenquan Wu, Jie Zeng, Yaxuan Liu, Yue Wang, Huixin Li, Taolin Xia, Weitao Liu, Zhe Lin, Wenfeng Xu

https://doi.org/10.18632/aging.205280pp 43—65

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Overexpression of MTFR1 promotes cancer progression and drug-resistance on cisplatin and is related to the immune microenvironment in lung adenocarcinoma

Qian-Yun Li, Qiang Guo, Wei-Min Luo, Xiang-Yu Luo, Yan-Mei Ji, Li-Qiang Xu, Jia-Long Guo, Rong-Shu Shi, Feng Li, Cheng-Yi Lin, Jun Zhang, Di Ke

https://doi.org/10.18632/aging.205338pp 66—88

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Characterization of m6A methylation modifications in gastric cancer

Wei Yin, Zhanwei Huo, Jiawei Zuo, Haixiao Wang, Bi Chen, Liqing Zhou

https://doi.org/10.18632/aging.205341pp 89—105

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Jian-Pi-Yi-Shen formula alleviates renal fibrosis by restoring NAD+ biosynthesis in vivo and in vitro

Liwen Gao, Xi Huang, Ruyu Deng, Shanshan Wu, Yu Peng, Guoliang Xiong, Jiandong Lu, Xinhui Liu

https://doi.org/10.18632/aging.205352pp 106—128

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Systematic analysis of the prognostic value and immunological function of LTBR in human cancer

Yinteng Wu, Shijian Zhao, Wenliang Guo, Ying Liu, Marìa Del Mar Requena Mullor, Raquel Alarcòn Rodrìguez, Ruqiong Wei

https://doi.org/10.18632/aging.205356pp 129—152

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Identification of aging-related genes in diagnosing osteoarthritis via integrating bioinformatics analysis and machine learning

Jian Huang, Jiangfei Zhou, Xiang Xue, Tianming Dai, Weicong Zhu, Songsong Jiao, Hang Wu, Qingqi Meng

https://doi.org/10.18632/aging.205357pp 153—168

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Impact of macrophage differentiation on hematopoietic function enhancement by Shenzhu ErKang Syrup

Yuan Li, Meng Teng, Hongxin Yang, Siyu Li, Xin Liu, Jicheng Zhang, Ye Qiu, Lanzhou Li

https://doi.org/10.18632/aging.205358pp 169—190

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Manganese and IL-12 treatment alters the ovarian tumor microenvironment

Yan Xu, Xin Huang, Xiao-Cui Nie, Yan-Song Liu, Yang Zhou, Ju-Min Niu

https://doi.org/10.18632/aging.205361pp 191—206

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Signatures of tumor-associated macrophages correlate with treatment response in ovarian cancer patients

Yang Gao, Yuwen Qi, Yin Shen, Yaxing Zhang, Dandan Wang, Min Su, Xuelian Liu, Anjin Wang, Wenwen Zhang, Can He, Junyuan Yang, Mengyuan Dai, Hua Wang, Hongbing Cai

https://doi.org/10.18632/aging.205362pp 207—225

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Aberrant RBMX expression is relevant for cancer prognosis and immunotherapy response

Yilei Sheng, Kunjian Lei, Chengpeng Sun, Jia Liu, Zewei Tu, Xingen Zhu, Kai Huang

https://doi.org/10.18632/aging.205363pp 226—245

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The potential value of the Purinergic pathway in the prognostic assessment and clinical application of kidney renal clear cell carcinoma

Deqian Xie, Shijin Wang, Bowen Jiang, Guandu Li, Guangzhen Wu

https://doi.org/10.18632/aging.205364pp 246—266

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A novel disulfidptosis-related lncRNAs signature for predicting survival and immune response in hepatocellular carcinoma

Zhoubo Guo, Yan Xie, Li Zhang, Shuaichen Liu, Wentao Jiang

https://doi.org/10.18632/aging.205367pp 267—284

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MAGE-A11 is a potential prognostic biomarker and immunotherapeutic target in gastric cancer

Zhi-Wen Wang, Qi-Ying Yu, Meng-Jiao Xu, Chuan-Yi Zhou, Jia-Peng Li, Xing-Hua Liao

https://doi.org/10.18632/aging.205368pp 285—298

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METTL3-dependent N6-methyladenosine modification is involved in berberine-mediated neuroprotection in ischemic stroke by enhancing the stability of NEAT1 in astrocytes

Junya Hu, Huijie Duan, Junqing Zou, Wangli Ding, Ziqiao Wei, Qiang Peng, Zhongyuan Li, Rui Duan, Jianguo Sun, Junrong Zhu

https://doi.org/10.18632/aging.205369pp 299—321

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Clinical significance and immune characteristics analysis of miR-221-3p and its key target genes related to epithelial-mesenchymal transition in breast cancer

Yutong Fang, Qunchen Zhang, Zexiao Chen, Cuiping Guo, Jundong Wu

https://doi.org/10.18632/aging.205370pp 322—347

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SNRPB promotes the progression of hepatocellular carcinoma via regulating cell cycle, oxidative stress, and ferroptosis

Xiaoyan Wang, Hao Zhang, Zehao Guo, Junyuan Wang, Chuntao Lu, Junhua Wang, Rongzhong Jin, Zhijing Mo

https://doi.org/10.18632/aging.205371pp 348—366

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Multidimensional comprehensive and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status

Ping Xi, Zhicheng Zhang, Yifu Liu, Yechen Nie, Binbin Gong, Ji Liu, Hao Huang, Ziwen Liu, Ting Sun, Wenjie Xie

https://doi.org/10.18632/aging.205372pp 367—388

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The predictive value of sarcopenia and myosteatosis in trans-arterial (chemo)-embolization treated HCC patients

Jing Long, Xin Zhang, Wei Mi, Jianjun Shi, Hongwei Ren, Qiang Wang

https://doi.org/10.18632/aging.205375pp 389—401

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Deciphering the prognostic significance of anoikis-related lncRNAs in invasive breast cancer: from comprehensive bioinformatics analysis to functional experimental validation

Wenge Dong, Jiejing Li, Zhigang Zhuang

https://doi.org/10.18632/aging.205376pp 402—430

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TBC1D1 represses glioma progression by altering the integrity of the cytoskeleton

Jiahong Cai, Yong’an Jiang, Peng Chen, Jiawei Liang, Yi Zhang, Raorao Yuan, Hengyi Fan, Yuefei Zhong, Jianhui Cai, Shiqi Cheng, Yan Zhang

https://doi.org/10.18632/aging.205377pp 431—444

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Tumor-associated macrophages and PD-L1 in prostate cancer: a possible key to unlocking immunotherapy efficacy

Jinhuan Wang, Wenqi Wu, Tian Yuan, Lili Wang, Li Zang, Qing Liu, Lei Wang, Xiaodong Huo, Bin Huo, Yong Tang, Haitao Wang, Zhigang Zhao

https://doi.org/10.18632/aging.205378pp 445—465

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G6PD is a prognostic biomarker correlated with immune infiltrates in lung adenocarcinoma and pulmonary arterial hypertension

Rongzhen Ding, Shuliu Sang, Jian Yi, Haiping Xie, Feiying Wang, Aiguo Dai

https://doi.org/10.18632/aging.205381pp 466—492

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Predicting prognosis and immune status in sarcomas by identifying necroptosis-related lncRNAs

Zhen Wang, Anfang He, Zhengyu Lu, Wenli Xu, Gang Wu, Tingsheng Peng

https://doi.org/10.18632/aging.205383pp 493—517

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New perspectives on the potential of tetrandrine in the treatment of non-small cell lung cancer: bioinformatics, Mendelian randomization study and experimental investigation

Jihang Luo, Xiaocong Mo, Di Hu, Yin Li, Meng Xu

https://doi.org/10.18632/aging.205384pp 518—537

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RBCK1 overexpression is associated with immune cell infiltration and poor prognosis in hepatocellular carcinoma

Jingjing Yu, Tianming Liu, Mingjiang Liu, Hu Jin, Zaiwa Wei

https://doi.org/10.18632/aging.205393pp 538—549

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Effectiveness and safety of afatinib, gefitinib, and erlotinib for treatment-naïve elderly patients with epidermal growth factor receptor-mutated advanced non-small-cell lung cancer: a multi-institute retrospective study

Ling-Jen Hung, Ping-Chih Hsu, Cheng-Ta Yang, Chih-Hsi Scott Kuo, John Wen-Cheng Chang, Chen-Yang Huang, Ching-Fu Chang, Chiao-En Wu

https://doi.org/10.18632/aging.205395pp 550—567

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Immune landscape and heterogeneity of cervical squamous cell carcinoma and adenocarcinoma

Binghan Liu, Yashi Xu, Bai Hu, Xiaole Song, Shitong Lin, Jiaxuan Wang, Lingfang Wang, Tian Chu, Ting Peng, Miaochun Xu, Wencheng Ding, Canhui Cao, Peng Wu, Li Li

https://doi.org/10.18632/aging.205397pp 568—592

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Integrated multi-omics analyses reveal the TM4SF family genes with prognostic and therapeutic relevance in hepatocellular carcinoma

Qiang Tang, Shurui Wang, Huimin Li, Junzhi Liu, Xin Hu, Dong Zhao, Maojun Di

https://doi.org/10.18632/aging.205398pp 593—616

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GDF15 restrains myocardial ischemia-reperfusion injury through inhibiting GPX4 mediated ferroptosis

Qingfeng Gao, Chao Li, Peiqi Zhong, Yunqiang Yu, Zhurong Luo, Hao Chen

https://doi.org/10.18632/aging.205402pp 617—626

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Targeting of FSP1 regulates iron homeostasis in drug-tolerant persister head and neck cancer cells via lipid-metabolism-driven ferroptosis

Yang-Che Wu, Chin-Sheng Huang, Ming-Shou Hsieh, Chih-Ming Huang, Syahru Agung Setiawan, Chi-Tai Yeh, Kuang-Tai Kuo, Shao-Cheng Liu

https://doi.org/10.18632/aging.205409pp 627—647

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Danggui-Shaoyao-San (DSS) ameliorates the progression of osteoarthritis via suppressing the NF-κB signaling pathway: an in vitro and in vivo study combined with bioinformatics analysis

Shuai Chen, Pan Kang, Zhuanglin Zhao, Hongyi Zhang, Jianliang Li, Kun Xu, Dawei Gong, Feng Jiao, Haibin Wang, Meng Zhang

https://doi.org/10.18632/aging.205410pp 648—664

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The anoikis-related gene signature predicts survival and correlates with immune infiltration in osteosarcoma

Junqing Li, Hui Wang, Feiran Wu, Jie Yao, Huimin Zhu, Meng Zhang

https://doi.org/10.18632/aging.205411pp 665—684

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ZIP4 upregulation aggravates nucleus pulposus cell degradation by promoting inflammation and oxidative stress by mediating the HDAC4-FoxO3a axis

Mingkui Shen, Kuankuan Li, Lulu Wang, Li Feng, Xinyu Zhang, Haoping Zhang, Honggang Zhou, Guoxian Pei

https://doi.org/10.18632/aging.205412pp 685—700

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Platelet-derived growth factor subunit-B mediating the effect of dickkopf-1 on acute myocardial infarction risk: a two-step Mendelian randomization study

Jun-Shan Li, Peng-Fei Zheng, Jing-Jing Rong, Zhao-Fen Zheng, Zheng-Yu Liu, Chang-Lu Wang

https://doi.org/10.18632/aging.205413pp 701—713

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LAMP3 is a potent uterine corpus endometrial carcinoma prognostic biomarker associated with immune behavior

Bidong Fu, Minqin Zhou, Xitong Geng, Yike Jiang, Hong Zeng, Xuanrui Zhou, Zichuan Yu, Jingying Pan, Yanting Zhu, Hao Zheng, Shuhan Huang, Yiyang Gong, Da Huang, Yanying Zhong

https://doi.org/10.18632/aging.205414pp 714—745

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