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Page: 12 of 2

• Research PaperVolume 16, Issue 7pp 6364-6383

  Metabolic score for insulin resistance predicts major adverse cardiovascular event in premature coronary artery disease

  Relevance score: 0.00

  Dachuan Guo, Chong Zhang, Mingyan Zhang, Zhenguo Wu, Xiaoyu Liu, Yerui Zhang, Li Liu, Meili Sun, Jianmin Yang

  Keywords: premature coronary artery disease, insulin resistance, major adverse cardiovascular events, prognosis, metabolic score for insulin resistance

  Published in Aging on April 1, 2024

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• Research PaperVolume 16, Issue 1pp 844-856

  Melatonin regulates autophagy in granulosa cells from patients with premature ovarian insufficiency via activating Foxo3a

  Relevance score: 0.00

  Pengfen Li, Qian Dou, Dan Zhang, Yungai Xiang, Li Tan

  Keywords: melatonin, autophagy, granulosa cells, premature ovarian insufficiency, forkhead box O-3A

  Published in Aging on January 10, 2024

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• EditorialVolume 15, Issue 15pp 7336-7337

  Insights into aging from progeroid syndrome epigenetics

  Relevance score: 0.00

  Yosra Bejaoui, Junko Oshima, Nady El Hajj

  Keywords: premature aging, epigenetics, progeroid syndromes, epigenetic clocks, DNA methylation

  Published in Aging on August 5, 2023

• Research PaperVolume 14, Issue 4pp 1651-1664

  Mitochondrial dysfunction in mandibular hypoplasia, deafness and progeroid features with concomitant lipodystrophy (MDPL) patients

  Relevance score: 0.00

  Michela Murdocca, Paola Spitalieri, Angela Cappello, Fiorella Colasuonno, Sandra Moreno, Eleonora Candi, Maria Rosaria D'Apice, Giuseppe Novelli, Federica Sangiuolo

  Keywords: premature aging syndrome, MDPL syndrome, mitochondria, SOD2, ROS production, metformin, autophagy, FIB/SEM

  Published in Aging on February 23, 2022

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• Research PaperVolume 13, Issue 11pp 15193-15213

  TRDMT1 participates in the DNA damage repair of granulosa cells in premature ovarian failure

  Relevance score: 0.00

  Chunli Sha, Lu Chen, Li Lin, Taoqiong Li, Hong Wei, Meiling Yang, Wujiang Gao, Dan Zhao, Qi Chen, Yueqin Liu, Xiaofang Chen, Wenlin Xu, Yuefeng Li, Xiaolan Zhu

  Keywords: premature ovarian failure, ROS, TRDMT1, DNA damage, granulosa cells

  Published in Aging on June 8, 2021

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• EditorialVolume 12, Issue 3pp 2022-2023

  Lessons for aging from Werner syndrome epigenetics

  Relevance score: 0.00

  George M. Martin, Martin Poot, Thomas Haaf

  Keywords: premature aging, developmental origins, epigenetic changes, transcriptional disease, Werner syndrome

  Published in Aging on February 5, 2020

• Research PaperVolume 11, Issue 1pp 127-159

  Premature aging and cancer development in transgenic mice lacking functional CYLD

  Relevance score: 0.00

  Josefa P. Alameda, Ángel Ramírez, Rosa A. García-Fernández, Manuel Navarro, Angustias Page, José C. Segovia, Rebeca Sanchez, Cristian Suárez-Cabrera, Jesús M. Paramio, Ana Bravo, M. Jesús Fernández-Aceñero, M. Llanos Casanova

  Keywords: CYLD, premature aging, tumor suppressor, NF-κB, keratinocyte differentiation, skin, inflammation

  Published in Aging on January 10, 2019

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• Research PaperVolume 8, Issue 10pp 2392-2406

  Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice

  Relevance score: 0.00

  Joohwee Kim, Vivek Vaish, Mingxiao Feng, Kevin Field, Ioulia Chatzistamou, Minsub Shim

  Keywords: premature aging, COX2, TP53, p16, prostaglandin

  Published in Aging on October 7, 2016

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• Research PaperVolume 18, Issue 1pp 262-281

  Modeling premature aging in yeast via the expression of Progerin

  Relevance score: 0.00

  Zachery R. Belak, Christopher Ptak, Rachel E. Harris, Rick Wozniak, Christopher H. Eskiw, Troy AA. Harkness

  Keywords: Hutchinson-Gilford Progeria Syndrome, yeast, Progerin, Lamin A, premature aging

  Published in Aging on April 3, 2026

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• Research Paper

  Chronic stress promotes premature ovarian failure in mice by inhibiting ovarian granulosa cell autophagy through PI3K-AKTmTOR pathway

  Relevance score: 0.00

  Zhibin Zhao, Xuefei Yuan, Baohua Zhao, Kai He

  Keywords: PI3K-AKT-mTOR pathway, premature ovarian failure (POF), ovarian granulosa cells (OGCs), chronic stress

  Published in Aging on October 8, 2024

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• Research PaperVolume 12, Issue 2pp 1910-1927

  Effect of antioxidants on the H₂O₂-induced premature senescence of human fibroblasts

  Relevance score: 0.00

  Natalia Pieńkowska, Grzegorz Bartosz, Monika Pichla, Michalina Grzesik-Pietrasiewicz, Martyna Gruchala, Izabela Sadowska-Bartosz

  Keywords: stress-induced premature senescence, fibroblasts, antioxidants, hydrogen peroxide

  Published in Aging on January 21, 2020

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• Research PaperVolume 11, Issue 12pp 4145-4158

  Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice

  Relevance score: 0.00

  Santosh Kumar, Shubhankar Suman, Albert J Fornace, Kamal Datta

  Keywords: heavy ion radiation, space radiation, radiotherapy, intestinal stem cell, senescence, premature aging, SASP

  Published in Aging on June 25, 2019

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• Research PaperVolume 15, Issue 24pp 14553-14573

  Systemic changes induced by autologous stem cell ovarian transplant in plasma proteome of women with impaired ovarian reserves

  Relevance score: 0.00

  Anna Buigues, Noelia Ramírez-Martin, Jessica Martínez, Nuria Pellicer, Marcos Meseguer, Antonio Pellicer, Sonia Herraiz

  Keywords: plasma proteomic profile, autologous stem cell ovarian transplantation, poor ovarian response, premature ovarian insufficiency, aging

  Published in Aging on December 26, 2023

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• Research PaperVolume 15, Issue 19pp 9948-9964

  Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome

  Relevance score: 0.00

  Daisuke Sawada, Hisaya Kato, Hiyori Kaneko, Daisuke Kinoshita, Shinichiro Funayama, Takuya Minamizuka, Atsushi Takasaki, Katsushi Igarashi, Masaya Koshizaka, Aki Takada-Watanabe, Rito Nakamura, Kazuto Aono, Ayano Yamaguchi, Naoya Teramoto, Yukari Maeda, Tomohiro Ohno, Aiko Hayashi, Kana Ide, Shintaro Ide, Mayumi Shoji, Takumi Kitamoto, Yusuke Endo, Hideyuki Ogata, Yoshitaka Kubota, Nobuyuki Mitsukawa, Atsushi Iwama, Yasuo Ouchi, Naoya Takayama, Koji Eto, Katsunori Fujii, Tomozumi Takatani, Tadashi Shiohama, Hiromichi Hamada, Yoshiro Maezawa, Koutaro Yokote

  Keywords: Werner syndrome, premature aging, lipodystrophy, stromal vascular fraction, SASP

  Published in Aging on October 3, 2023

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• Research PaperVolume 14, Issue 24pp 10137-10152

  Moderate-vigorous physical activity attenuates premature senescence of immune cells in sedentary adults with obesity: a pilot randomized controlled trial

  Relevance score: 0.00

  Xiang-Ke Chen, Chen Zheng, Stephen Heung-Sang Wong, Alvin Chun-Hang Ma

  Keywords: physical inactivity, obesity, immune aging, premature senescence, senolytic

  Published in Aging on December 29, 2022

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• Research PaperVolume 12, Issue 24pp 26080-26094

  Postprandial triglyceride-rich lipoproteins-induced premature senescence of adipose-derived mesenchymal stem cells via the SIRT1/p53/Ac-p53/p21 axis through oxidative mechanism

  Relevance score: 0.00

  Qun-yan Xiang, Feng Tian, Xiao Du, Jin Xu, Li-yuan Zhu, Li-ling Guo, Tie Wen, You-shuo Liu, Ling Liu

  Keywords: triglyceride-rich lipoproteins, adipose-derived mesenchymal stem cells, premature senescence, SIRT1, oxidative stress

  Published in Aging on December 9, 2020

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• ReviewVolume 1, Issue 1pp 28-37

  Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A

  Relevance score: 0.00

  Phillip R. Musich, Yue Zou

  Keywords: Lamin A, Hutchinson-Gilford progeria syndrome, premature aging, Genome instability, DNA damage responses, XPA, DNA double strand breaks, DNA repair

  Published in Aging on January 16, 2009

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• Research PaperVolume 18, Issue 1pp 234-260

  A manually curated gene–phenotype catalogue for progeroid syndromes and premature aging

  Relevance score: 0.00

  Nuša Likar, Tanja Kunej

  Keywords: aging, premature aging, progeroid syndromes, DNA repair, LMNA gene

  Published in Aging on March 30, 2026

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• Research PaperVolume 17, Issue 10pp 2637-2649

  Establishment of an optimized chemotherapy-induced mouse model for premature ovarian failure: protocol and findings

  Relevance score: 0.00

  Negar Yavari, Narges Zaeemzadeh, Behrouz Gharesi-Fard, Negar Ajabi Ardehjani, Tayebeh Rastegar, Fardin Amidi

  Keywords: Busulfan, Cyclophosphamide, mice, premature ovarian failure

  Published in Aging on October 28, 2025

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• Research PaperVolume 17, Issue 4pp 937-959

  Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferation

  Relevance score: 0.00

  Sofie Lautrup, Shi-Qi Zhang, Shinichiro Funayama, Lisa Lirussi, Tina Visnovska, Hoi-Hung Cheung, Marc Niere, Yuyao Tian, Hilde Loge Nilsen, Geir Selbæk, Janna Saarela, Yoshiro Maezawa, Koutaro Yokote, Per Nilsson, Wai-Yee Chan, Hisaya Kato, Mathias Ziegler, Vilhelm A. Bohr, Evandro F. Fang

  Keywords: Werner syndrome, premature aging, NAD+, mitochondria, proliferation

  Published in Aging on April 2, 2025

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