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Volume 17, Issue 10

October 31, 2025pp 2452—2654

About the Cover

The cover features Figure 4 " Cortical transcriptomic perturbations under SNCA overload include myelination-linked genes in rat and PD patients" from Hoof et al.

Editorial

Longevity clinics: between promise and peril

Marco Demaria

https://doi.org/10.18632/aging.206330pp 2452—2454

Research Papers

Longitudinal associations of epigenetic aging with cognitive aging in Hispanic/Latino adults from the Hispanic Community Health Study/Study of Latinos

Myriam Fornage, Wassim Tarraf, Rui Xia, Adriana Ordonez, Tamar Sofer, Freddie Márquez, Bharat Thyagarajan, Gregory A. Talavera, Linda C. Gallo, Charles DeCarli, Hector M. González

https://doi.org/10.18632/aging.206317pp 2455—2474

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L-β-aminoisobutyric acid (L-BAIBA) in combination with voluntary wheel running exercise enhances musculoskeletal properties in middle-age male mice

Julian A. Vallejo, Yukiko Kitase, Thiagarajan Ganesh, Mark Dallas, Yixia Xie, David S. Moore, Mark L. Johnson, Lynda F. Bonewald, Michael J. Wacker

https://doi.org/10.18632/aging.206325pp 2475—2499

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The role of phenylalanine and tyrosine in longevity: a cohort and Mendelian randomization study

Jie V. Zhao, Yitang Sun, Junmeng Zhang, Kaixiong Ye

https://doi.org/10.18632/aging.206326pp 2500—2533

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Growth hormone excess drives liver aging via increased glycation stress

Parminder Singh, Anil Gautam, Marissa N. Trujillo, Praveen Singh, Lizbeth Enriquez Najera, James J. Galligan, Lisa Hensley, Pankaj Kapahi, Andrzej Bartke

https://doi.org/10.18632/aging.206327pp 2534—2551

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Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos

Andres Reig, Emre Seli

https://doi.org/10.18632/aging.206328pp 2552—2560

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Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis

Wei Yu Chua, Jia Dong James Wang, Claire Kar Min Chan, Ling-Ling Chan, Eng-King Tan

https://doi.org/10.18632/aging.206329pp 2561—2581

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Identification of key genes with differential correlations in prostate cancer

Zepai Chi, Yuanfeng Zhang, Xuwei Hong, Tenghao Yang, Qingchun Xu, Weiqiang Lin, Yueying Huang, Yonghai Zhang

https://doi.org/10.18632/aging.206323pp 2582—2597

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Brain region-specific and systemic transcriptomic alterations in a human alpha-synuclein overexpressing rat model

Vivien Hoof, Nicolas Casadei, Olaf Riess, Julia Schulze-Hentrich, Thomas Hentrich

https://doi.org/10.18632/aging.206331pp 2598—2636

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Establishment of an optimized chemotherapy-induced mouse model for premature ovarian failure: protocol and findings

Negar Yavari, Narges Zaeemzadeh, Behrouz Gharesi-Fard, Negar Ajabi Ardehjani, Tayebeh Rastegar, Fardin Amidi

https://doi.org/10.18632/aging.206332pp 2637—2649

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Correction

Correction for: ESRP1 regulates alternative splicing of CARM1 to sensitize small cell lung cancer cells to chemotherapy by inhibiting TGF-β/Smad signaling

Meng Zheng, Yuchun Niu, Junguo Bu, Shumei Liang, Zhilin Zhang, Jianhua Liu, Linlang Guo, Zhihua Zhang, Qiongyao Wang

https://doi.org/10.18632/aging.206334pp 2650—2651

Retraction

Retraction of: Extracellular vesicle derived miR-544 downregulates expression of tumor suppressor promyelocytic leukemia zinc finger resulting in increased peritoneal metastasis in gastric cancer

Wencheng Kong, Xinchun Liu, Guang Yin, Sixin Zheng, Akao Zhu, Panpan Yu, Yuqiang Shan, Rongchao Ying, Jian Zhang

https://doi.org/10.18632/aging.206324pp 2652—2654