Volume 8, Issue 10

October 2016
pp 2256—2604

About the Cover

The cover for issue 10 of Aging features Figure 2G, ''Transgenic expression of cyclooxygenase‐2 (COX2) causes premature aging phenotypes in mice" from Kim et al.

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Editorials

p63 role in breast cancer

Simone Di Franco, Gianluca Sala, Matilde Todaro,

https://doi.org/10.18632/aging.101042 pp 2256—2257

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Combinations of targeted therapies in human cancers

Didier Decaudin, Christophe Le Tourneau,

https://doi.org/10.18632/aging.101085 pp 2258—2259

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Genomic profiling of collecting duct renal carcinoma

Sreenivasulu Chintala, Roberto Pili,

https://doi.org/10.18632/aging.101109 pp 2260—2261

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Widening the concept of oncogene

Sergio Casas-Tintó, Marta Portela, Alberto Ferrús,

https://doi.org/10.18632/aging.101111 pp 2262—2263

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Reviews

The role of hydrogen sulfide in aging and age-related pathologies

Bernard W. Perridon, Henri G.D. Leuvenink, Jan-Luuk Hillebrands, Harry van Goor, Eelke M. Bos,

https://doi.org/10.18632/aging.101026 pp 2264—2289

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The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis

Munehiro Kitada, Yoshio Ogura, Daisuke Koya,

https://doi.org/10.18632/aging.101068 pp 2290—2307

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Research Papers

SIRT6 delays cellular senescence by promoting p27Kip1 ubiquitin-proteasome degradation

Ganye Zhao, Hui Wang, Chenzhong Xu, Pan Wang, Jun Chen, Pengfeng Wang, Zhaomeng Sun, Yuanyuan Su, Zhao Wang, Limin Han, Tanjun Tong,

https://doi.org/10.18632/aging.101038 pp 2308—2323

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A comprehensive transcriptomic analysis of differentiating embryonic stem cells in response to the overexpression of Mesogenin 1

Dahai Liu, Qiang Zhang, Hong Zhang, Ling Tang, Wei Li, Dongming Zhang, Guoying Wu, Shoudong Ye, Qian Ban, Kan He,

https://doi.org/10.18632/aging.101049 pp 2324—2336

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TGF-β and NF-κB signaling pathway crosstalk potentiates corneal epithelial senescence through an RNA stress response

Zhi-Yuan Li, Zhao-Li Chen, Ting Zhang, Chao Wei, Wei-Yun Shi,

https://doi.org/10.18632/aging.101050 pp 2337—2354

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Caveolin-1 controls mitochondrial function through regulation of m-AAA mitochondrial protease

Daniela Volonte, Zhongmin Liu, Sruti Shiva, Ferruccio Galbiati,

https://doi.org/10.18632/aging.101051 pp 2355—2369

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A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated

Kathleen E. Fischer, Jessica M. Hoffman, Lauren B. Sloane, Jonathan A.L. Gelfond, Vanessa Y. Soto, Arlan G. Richardson, Steven N. Austad,

https://doi.org/10.18632/aging.101059 pp 2370—2391

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Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice

Joohwee Kim, Vivek Vaish, Mingxiao Feng, Kevin Field, Ioulia Chatzistamou, Minsub Shim,

https://doi.org/10.18632/aging.101060 pp 2392—2406

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Height indicates hematopoietic capacity in elderly Japanese men

Yuji Shimizu, Shimpei Sato, Jun Koyamatsu, Hirotomo Yamanashi, Mako Nagayoshi, Koichiro Kadota, Takahiro Maeda,

https://doi.org/10.18632/aging.101061 pp 2407—2413

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Lower circulating insulin-like growth factor-I is associated with better cognition in females with exceptional longevity without compromise to muscle mass and function

Leland Perice, Nir Barzilai, Joe Verghese, Erica F. Weiss, Roee Holtzer, Pinchas Cohen, Sofiya Milman,

https://doi.org/10.18632/aging.101063 pp 2414—2424

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Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration

Amelia Pollard, Freya Shephard, James Freed, Susan Liddell, Lisa Chakrabarti,

https://doi.org/10.18632/aging.101064 pp 2425—2436

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Clustering of geriatric deficits emerges to be an essential feature of ageing - results of a cross-sectional study in Poland

Karolina Piotrowicz, Agnieszka Pac, Anna Barbara Skalska, Jerzy Chudek, Alicja Klich-Rączka, Aleksandra Szybalska, Jean-Pierre Michel, Tomasz Grodzicki,

https://doi.org/10.18632/aging.101055 pp 2437—2448

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Inducing cellular senescence in vitro by using genetically encoded photosensitizers

Nadezhda V. Petrova, Artem V. Luzhin, Ekaterina O. Serebrovskaya, Alina P. Ryumina, Artem K. Velichko, Sergey V. Razin, Omar L. Kantidze,

https://doi.org/10.18632/aging.101065 pp 2449—2462

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Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury

Thomas Broggini, Lisa Schnell, Ali Ghoochani, José María Mateos, Michael Buchfelder, Kurt Wiendieck, Michael K. Schäfer, Ilker Y. Eyupoglu, Nicolai E. Savaskan,

https://doi.org/10.18632/aging.101066 pp 2463—2487

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Dissociation between iron accumulation and ferritin upregulation in the aged substantia nigra: attenuation by dietary restriction

Thomas Walker, Christos Michaelides, Antigoni Ekonomou, Kalotina Geraki, Harold G Parkes, Maria Suessmilch, Amy H Herlihy, William R Crum, Po-Wah So,

https://doi.org/10.18632/aging.101069 pp 2488—2508

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MicroRNA-346 facilitates cell growth and metastasis, and suppresses cell apoptosis in human non-small cell lung cancer by regulation of XPC/ERK/Snail/E-cadherin pathway

Cheng-Cao Sun, Shu-Jun Li, Zhan-Peng Yuan, De-Jia Li,

https://doi.org/10.18632/aging.101080 pp 2509—2524

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Impaired autophagy activity is linked to elevated ER-stress and inflammation in aging adipose tissue

Amiya Kumar Ghosh, Theresa Mau, Martin O’Brien, Sanjay Garg, Raymond Yung,

https://doi.org/10.18632/aging.101083 pp 2525—2537

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Prenatal hyperbaric normoxia treatment improves healthspan and regulates chitin metabolic genes in Drosophila melanogaster

Suyeun Yu, Eunil Lee, Bodokhsuren Tsogbadrakh, Gwang-Ic Son, Mari Kim,

https://doi.org/10.18632/aging.101084 pp 2538—2550

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Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria

Satomi Miwa, Rafal Czapiewski, Tengfei Wan, Amy Bell, Kirsten N. Hill, Thomas von Zglinicki, Gabriele Saretzki,

https://doi.org/10.18632/aging.101089 pp 2551—2567

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Empirical verification of evolutionary theories of aging

Pavlo Kyryakov, Alejandra Gomez-Perez, Anastasia Glebov, Nimara Asbah, Luigi Bruno, Carolynne Meunier, Tatiana Iouk, Vladimir I. Titorenko,

https://doi.org/10.18632/aging.101090 pp 2568—2589

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Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice

Brian C. Grieb, Kelli Boyd, Ramkrishna Mitra, Christine M. Eischen,

https://doi.org/10.18632/aging.101092 pp 2590—2602

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Letter to the Editor

Lower mortality rates in those living at moderate altitude

Martin Burtscher,

https://doi.org/10.18632/aging.101057 pp 2603—2604

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