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• EditorialVolume 8, Issue 11pp 2605-2606

  Developing cancer therapies – think global

  Relevance score: 0.00

  Andrew D. Hollenbach

  Keywords: Alveolar Rhabdomyosarcoma, pathway analysis, multi-faceted treatment regimen, cancer therapies

  Published in Aging on November 16, 2016

• Research PaperVolume 11, Issue 8pp 2378-2387

  Replicative and radiation-induced aging: a comparison of gene expression profiles

  Relevance score: 0.00

  Alexander M. Aliper, Marine E. Bozdaganyan, Philipp S. Orekhov, Alex Zhavoronkov, Andreyan N. Osipov

  Keywords: replicative aging, ionizing radiation, transcriptome analysis, signal pathway transduction

  Published in Aging on April 19, 2019

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• Research PaperVolume 15, Issue 17pp 8930-8947

  A comprehensive survival and prognosis analysis of GPR55 expression in hepatocellular carcinoma

  Relevance score: 0.00

  Tianyu Wang, Kang Xia, Tao Qiu, Shangting Han, Zhongbao Chen, Xiaoxiong Ma, Long Zhang, Jilin Zou, Yalong Zhang, Bo Yu, Chenyang Kong, Jiayu Guo, Yiting Liu, Jiangqiao Zhou, Shusen Zheng

  Keywords: survival and prognosis analysis, GPR55, hepatocellular carcinoma, mitogen-activated protein kinase signaling pathway

  Published in Aging on September 8, 2023

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• Research PaperVolume 15, Issue 17pp 8976-8992

  Herpesvirus latent infection promotes stroke via activating the OTUD1/NF-κB signaling pathway

  Relevance score: 0.00

  Jiacai Lin, Yangrui Zheng, Ning Zhao, Fang Cui, Siting Wu

  Keywords: cerebral infarction, herpes virus, latent infection, OTUD1/NF-κB signaling pathway, evidence-based medicine meta-analysis, bioinformatics

  Published in Aging on September 9, 2023

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• Research PaperVolume 14, Issue 24pp 10153-10170

  Sevoflurane postconditioning ameliorates cerebral ischemia-reperfusion injury in rats via TLR4/MyD88/TRAF6 signaling pathway

  Relevance score: 0.00

  Zijun Zhao, Yishuai Li, Fei Chi, Li Ma, Yanan Li, Zhiyong Hou, Qiujun Wang

  Keywords: sevoflurane postconditioning, TLR4/MyD88/TRAF6 signaling pathway, erebral ischemia-reperfusion, neuroinflammation, bioinformatics analysis

  Published in Aging on December 29, 2022

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• Research PaperVolume 16, Issue 4pp 3955-3972

  Protective effects of triptolide against oxidative stress in retinal pigment epithelium cells via the PI3K/AKT/Nrf2 pathway: a network pharmacological method and experimental validation

  Relevance score: 0.00

  Fuying Pan, Qinxin Shu, Hao Xie, Long Zhao, Ping Wu, Yong Du, Jing Lu, Yuxia He, Xing Wang, Hui Peng

  Keywords: triptolide, oxidative stress, PI3K/Akt/Nrf2 pathway, network pharmacological analysis

  Published in Aging on February 21, 2024

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• Research PaperVolume 13, Issue 18pp 22474-22489

  Identification of genes and pathways leading to metastasis and poor prognosis in melanoma

  Relevance score: 0.00

  Xin Zhang, Wandong Wang, Yun Wang, Guan Jiang

  Keywords: melanoma, bioinformatics, signaling pathway, survival analysis, regulatory analysis

  Published in Aging on September 28, 2021

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• Research PaperVolume 6, Issue 12pp 1064-1075

  Pathway activation profiling reveals new insights into Age-related Macular Degeneration and provides avenues for therapeutic interventions

  Relevance score: 0.00

  Evgeny Makarev, Charles Cantor, Alex Zhavoronkov, Anton Buzdin, Alexander Aliper, Antonei Benjamin Csoka

  Keywords: AMD, Age-related Macular Degeneration, gene expression, Transcriptome profiling, signaling pathway activation strength

  Published in Aging on December 22, 2014

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• Research PaperVolume 14, Issue 1pp 286-296

  Yes-associated protein reacts differently in vascular smooth muscle cells under different intensities of mechanical stretch

  Relevance score: 0.00

  Xinhao Wang, Xiangdang Liang, Lujun Zhou, Shen Liu, Zhuoqun Fang, Chuanzhong Hu, Yigong Hou, Zhanshe Guo

  Keywords: Hippo pathway, YAP, mechanical stretch, proliferation, apoptosis

  Published in Aging on January 4, 2022

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• Research PaperVolume 7, Issue 1pp 26-37

  Signaling pathway activation drift during aging: Hutchinson-Gilford Progeria Syndrome fibroblasts are comparable to normal middle-age and old-age cells

  Relevance score: 0.00

  Alexander M. Aliper, Antonei Benjamin Csoka, Anton Buzdin, Tomasz Jetka, Sergey Roumiantsev, Alexey Moskalev, Alex Zhavoronkov

  Keywords: Progeria, HGPS, Lamin, LMNA, aging, aging pathway, pathway activation, pathway drift, geroscope, geroprotectors, senescence

  Published in Aging on January 9, 2015

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• Research PaperVolume 6, Issue 3pp 207-214

  Hexosamine pathway but not interstitial changes mediates glucotoxicity in pancreatic β-cells as assessed by cytosolic Ca²⁺ response to glucose

  Relevance score: 0.00

  Kazuhiro Yanagida, Yuko Maejima, Putra Santoso, Zesemdorj Otgon-Uul, Yifei Yang, Kazuya Sakuma, Kenju Shimomura, Toshihiko Yada

  Keywords: Glucotoxicity, hexosamine pathway, insulin secretion

  Published in Aging on March 29, 2014

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• Research PaperVolume 4, Issue 10pp 715-722

  New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53^−/− mice by delaying carcinogenesis

  Relevance score: 0.00

  Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski, Olga B. Chernova, Alexander Polinsky, Mikhail V. Blagosklonny, Andrei V. Gudkov, Marina P. Antoch

  Keywords: mTOR pathway, p53−/−, lifespan, rapamycin, oral formulation, cancer prevention

  Published in Aging on October 29, 2012

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• Research Paper

  Chronic stress promotes premature ovarian failure in mice by inhibiting ovarian granulosa cell autophagy through PI3K-AKTmTOR pathway

  Relevance score: 0.00

  Zhibin Zhao, Xuefei Yuan, Baohua Zhao, Kai He

  Keywords: PI3K-AKT-mTOR pathway, premature ovarian failure (POF), ovarian granulosa cells (OGCs), chronic stress

  Published in Aging on October 8, 2024

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• Research PaperVolume 16, Issue 2pp 1516-1535

  Molecular map of cGAS-STING pathway-related genes in bladder cancer: the perspective toward immune microenvironment and prognosis

  Relevance score: 0.00

  Dong Wei, Ying Liu, Ying Yuan, Yishuai Li, Fangchao Zhao, Xuebo Qin

  Keywords: cGAS-STING pathway, bladder cancer, tumor immune, immune microenvironment, immune checkpoint inhibitors

  Published in Aging on January 17, 2024

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• Research PaperVolume 15, Issue 12pp 5426-5444

  Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway

  Relevance score: 0.00

  Lin Li, Hangyu Jiang, Yuqi Li, Xiaochong Xiang, Yueming Chu, Jie Tang, Kang Liu, Danqun Huo, Xiaofen Zhang

  Keywords: esophageal squamous cell carcinoma, chaetocin, ROS, Hippo pathway, apoptosis

  Published in Aging on June 14, 2023

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• Research PaperVolume 15, Issue 4pp 1210-1227

  Inhibition of apoptosis through AKT-mTOR pathway in ovarian cancer and renal cancer

  Relevance score: 0.00

  Hongrun Chen, Lianfeng Zhang, Meini Zuo, Xiaowen Lou, Bin Liu, Taozhu Fu

  Keywords: Akt-mTOR pathway, renal cancer, ovarian cancer, bioinformatics, verification, biomarker

  Published in Aging on February 27, 2023

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• Research PaperVolume 15, Issue 9pp 3381-3393

  PI3K-Akt signaling pathway based on network pharmacology for the anti-Alzheimer’s disease effect of licorice stem flavonoids

  Relevance score: 0.00

  Hongyan Pei, Lei He, Meiling Shi, Xiangjuan Guo, Weijia Chen, Jianming Li, Zhongmei He, Rui Du

  Keywords: network pharmacology, Alzheimer’s disease, licorice stem flavonoids, PI3K-Akt signalling pathway

  Published in Aging on February 22, 2023

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• Research PaperVolume 14, Issue 12pp 5250-5270

  TRPM7 via calcineurin/NFAT pathway mediates metastasis and chemotherapeutic resistance in head and neck squamous cell carcinoma

  Relevance score: 0.00

  Tsung-Ming Chen, Chih-Ming Huang, Ming-Shou Hsieh, Chun-Shu Lin, Wei-Hwa Lee, Chi-Tai Yeh, Shao-Cheng Liu

  Keywords: HNSCC, transient receptor potential cation channel subfamily M member 7, chemoresistance, calcineurin/NFAT pathway, cancer stem cell

  Published in Aging on June 29, 2022

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• Research PaperVolume 13, Issue 1pp 1096-1119

  The endothelial nitric oxide synthase/cyclic guanosine monophosphate/protein kinase G pathway activates primordial follicles

  Relevance score: 0.00

  Peikun Zhao, Zidai Song, Yan Wang, Han Cai, Xiaoyan Du, Changlong Li, Jianyi Lv, Xin Liu, Meng Guo, Zhenwen Chen

  Keywords: eNOS/cGMP/PKG pathway, mTOR, FBXW7, primordial follicle activation, ubiquitination

  Published in Aging on December 3, 2020

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• Research PaperVolume 12, Issue 10pp 9311-9327

  Single nucleotide polymorphisms within the Wnt pathway predict the risk of bone metastasis in patients with non-small cell lung cancer

  Relevance score: 0.00

  Yiquan Xu, Hongru Li, Lihong Weng, Yanqin Qiu, Junqiong Zheng, Huaqiang He, Dongmei Zheng, Junfan Pan, Fan Wu, Yusheng Chen

  Keywords: Wnt signaling pathway, polymorphisms, bone metastasis, risk, biomarker

  Published in Aging on May 26, 2020

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