Volume 15, Issue 12

30 June, 2023
pp 5230—5955

About the Cover

The cover features Figure 4 "Performance of age-predictive models built on various data types" from Salignon et al.

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Editorials

Advancing screening for cognitive impairment: the memtrax continuous recognition test

J. Wesson Ashford, James O. Clifford, Michael F. Bergeron,

https://doi.org/10.18632/aging.204828 pp 5230—5231

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Advances in cancer therapy: clinical benefit of new cancer drugs

Daniel Tobias Michaeli, Julia Caroline Michaeli, Thomas Michaeli,

https://doi.org/10.18632/aging.204839 pp 5232—5234

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A seed and soil model of gut dysbiosis in Alzheimer’s disease

Chun-Che Hung, Kristi M. Crowe-White, Ian M. McDonough,

https://doi.org/10.18632/aging.204840 pp 5235—5237

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Could social relationships be key to reaching healthy longevity?

Antonio Garrido, Mónica De la Fuente,

https://doi.org/10.18632/aging.204871 pp 5238—5239

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Research Papers

Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis

Jérôme Salignon, Omid R. Faridani, Tasso Miliotis, Georges E. Janssens, Ping Chen, Bader Zarrouki, Rickard Sandberg, Pia Davidsson, Christian G. Riedel,

https://doi.org/10.18632/aging.204787 pp 5240—5265

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Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome

Stephen E. Wilkie, Diana E. Marcu, Roderick N. Carter, Nicholas M. Morton, Susana Gonzalo, Colin Selman,

https://doi.org/10.18632/aging.204835 pp 5266—5278

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A novel peptide ‘T14’ reflects age and photo-aging in human skin

Sheila Rocha, Sara Garcia Ratés, Tumisang Moswete, Kristopher Kalleberg, Anna Villa, Jason P. Harcup, Susan A. Greenfield,

https://doi.org/10.18632/aging.204844 pp 5279—5289

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Neuroprotective effect of total flavonoids in stems and leaves of Glycyrrhiza uralensis Fisch. on oxidative stress in HT-22 cells and Caenorhabditis elegans

Weijia Chen, Lei He, Hongyan Pei, Jianming Li, Yan Zhao, Ying Zong, Hong Kan, Zhongmei He, Rui Du,

https://doi.org/10.18632/aging.204627 pp 5290—5303

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Construction and validation of a model based on immunogenic cell death-associated lncRNAs to predict prognosis and direct therapy for kidney renal clear cell carcinoma

Chenxi Cai, Kexin Shu, Wanying Chen, Jiatong Ding, Zishun Guo, Yiping Wei, Wenxiong Zhang,

https://doi.org/10.18632/aging.204741 pp 5304—5338

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Heterogeneity of tumor immune microenvironment in malignant and metastatic change in LUAD is revealed by single-cell RNA sequencing

Haiqiang Wang, Guoliang Han, Jiakuan Chen,

https://doi.org/10.18632/aging.204752 pp 5339—5354

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Construction and experimental validation of a B cell-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer

Ranran Zhou, Jiawei Zhou, Bahaerguli Muhuitijiang, Xiangbo Zeng, Wanlong Tan,

https://doi.org/10.18632/aging.204753 pp 5355—5380

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FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination

Songbai Liu, Peng Liu, Changhao Zhu, Rui Yang, Zhiwei He, Yongning Li, Ying Li, Xiaobin Fei, Junyi Hou, Xing Wang, Yaozhen Pan,

https://doi.org/10.18632/aging.204780 pp 5381—5398

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Comprehensive analysis reveals the involvement of hsa_circ_0037858/miR-5000-3p/FMR1 axis in malignant metastasis of clear cell renal cell carcinoma

Yuan Nianyong, Guowei Li,

https://doi.org/10.18632/aging.204790 pp 5399—5411

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Tumor-suppressive function and mechanism of miR-873-5p in glioblastoma: evidence based on bioinformatics analysis and experimental validation

Xiaobin Zhang, Fangkun Jing, Chen Guo, Xinning Li, Jianan Li, Guobiao Liang,

https://doi.org/10.18632/aging.204800 pp 5412—5425

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Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway

Lin Li, Hangyu Jiang, Yuqi Li, Xiaochong Xiang, Yueming Chu, Jie Tang, Kang Liu, Danqun Huo, Xiaofen Zhang,

https://doi.org/10.18632/aging.204801 pp 5426—5444

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Cross-talk of RNA modification "writers" describes tumor stemness and microenvironment and guides personalized immunotherapy for gastric cancer

Zhuoqi Li, Xuehong Zhang, Wenjie Weng, Ge Zhang, Qianwen Ren, Yuan Tian,

https://doi.org/10.18632/aging.204802 pp 5445—5481

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Dissecting the alternation landscape of mitochondrial metabolism-related genes in lung adenocarcinoma and their latent mechanisms

Xing Jin, Di Liu, Demiao Kong, Xiaojiang Zhou, Liken Zheng, Chuan Xu,

https://doi.org/10.18632/aging.204803 pp 5482—5496

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Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke

Longhui Fu, Beibei Yu, Yongfeng Zhang, Shuai Cao, Boqiang Lv, Yunze Tian, Huangtao Chen, Shijie Yang, Yutian Hu, Jinghua Hua, Pengyu Ren, Jianzhong Li, Shouping Gong,

https://doi.org/10.18632/aging.204804 pp 5497—5513

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hucMSCs treatment prevents pulmonary fibrosis by reducing circANKRD42-YAP1-mediated mechanical stiffness

Haitong Zhang, Qi Zhu, Yunxia Ji, Meirong Wang, Qian Zhang, Weili Liu, Ruiqiong Li, Jinjin Zhang, Pan Xu, Xiaodong Song, Changjun Lv,

https://doi.org/10.18632/aging.204805 pp 5514—5534

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Galectin-1-mediated high NCAPG expression correlates with poor prognosis in gastric cancer

Tingrui Zheng, Tao Qian, Haihua Zhou, Zhiyi Cheng, Guiyuan Liu, Chuanjiang Huang, Rongrong Dou, Fuxing Liu, Xiaolan You,

https://doi.org/10.18632/aging.204806 pp 5535—5549

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Mettl3-mediated m⁶A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression

Guanqi Dai, Shihao Huang, Yonglong Li, Xueyi Tu, Jiawei Xia, Zhihao Zhou, Wanyi Chen, Ao Zhang, Jintao Lin, Yingchun Li, Danhua He, Taoyan Lin, Jinge Cong, Ye Lei, Liuxin Han, Zhenxia Yao, Weiwei Liu, Ying Zhou, Qiwen Li, Jing Li, Yuqin Zhang, Aibing Wu, Dong Xiao, Wanshan Wang, Wentao Zhao, Junshuang Jia, Xiaolin Lin,

https://doi.org/10.18632/aging.204810 pp 5550—5568

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Expression, prognostic value and mechanism of SP100 family in pancreatic adenocarcinoma

Yunjie Duan, Yongxing Du, Yongrun Mu, Zongting Gu, Chengfeng Wang,

https://doi.org/10.18632/aging.204811 pp 5569—5591

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Significance of liquid-liquid phase separation (LLPS)-related genes in breast cancer: a multi-omics analysis

Jiaheng Xie, Liang Chen, Dan Wu, Shengxuan Liu, Shengbin Pei, Qikai Tang, Yue Wang, Mengmeng Ou, Zhechen Zhu, Shujie Ruan, Ming Wang, Jingping Shi,

https://doi.org/10.18632/aging.204812 pp 5592—5610

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Identifying the role of NUDCD1 in human tumors from clinical and molecular mechanisms: a study based on comprehensive bioinformatics and experimental validation

Bin Han, Jinsong He, Qing Chen, Min Yuan, Xi Zeng, Yuanting Li, Yan Zeng, Meibo He, Dan Feng, Daiyuan Ma,

https://doi.org/10.18632/aging.204813 pp 5611—5649

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Development and validation of a MUC16 mutation-associated immune prognostic model for lung adenocarcinoma

Honggang Liu, Tao Xin, Hongtao Duan, Yuanyong Wang, Changjian Shao, Yifang Zhu, Jiansheng Wang, Jianjun He,

https://doi.org/10.18632/aging.204814 pp 5650—5661

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Exploration of the effect of PUM1/Cripto-1 pathway on ferroptosis by regulating macrophage polarization in allogeneic blood transfused mice

Man-Di Wu, Yan Zhang, Huan Wang, Ke Yue, Yu Bai, Lai-Wei You, Ying-Hui Cui, Jian-Rong Guo,

https://doi.org/10.18632/aging.204818 pp 5662—5672

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DUSP10 is a novel immune-related biomarker connected with survival and cellular proliferation in lower-grade glioma

Feng Xiao, Hong Zhu, Yun Guo, Zhe Zhang, Gufeng Sun, Kai Huang, Hua Guo, Guowen Hu,

https://doi.org/10.18632/aging.204821 pp 5673—5697

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Sevoflurane upregulates neuron death process-related Ddit4 expression by NMDAR in the hippocampus

Shuai Li, Qi Hou, Runjia Wang, Yu Hou, Qiang Wang, Bo Zhang, Cheng Ni, Hui Zheng,

https://doi.org/10.18632/aging.204822 pp 5698—5712

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MAGOH is correlated with poor prognosis and is essential for cell proliferation in lower-grade glioma

Feng Xiao, Zhenli Long, Yun Guo, Hong Zhu, Zhe Zhang, Yao Xiao, Guowen Hu, Qing Yang, Kai Huang, Hua Guo,

https://doi.org/10.18632/aging.204823 pp 5713—5733

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lncSNHG3 drives breast cancer progression by epigenetically increasing CSNK2A1 expression level

Zhenlin Nie, Mu Xu, Linpeng Zhou, Bei Pan, Tao Xu, Bangshun He, Shukui Wang,

https://doi.org/10.18632/aging.204824 pp 5734—5750

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Construction of a T-cell exhaustion-related gene signature for predicting prognosis and immune response in hepatocellular carcinoma

Tianrui Kuang, Lilong Zhang, Dongqi Chai, Chen Chen, Weixing Wang,

https://doi.org/10.18632/aging.204830 pp 5751—5774

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Astaxanthin prevents osteoarthritis by blocking Rspo2-mediated Wnt/β-catenin signaling in chondrocytes and abolishing Rspo2-related inflammatory factors in macrophages

Chunhui Zhu, Gang Liu, Weiding Cui, Zhongjie Yu, Wei Chen, Yao Qin, Jiuxiang Liu, Yaojun Lu, Weimin Fan, Wenwei Liang,

https://doi.org/10.18632/aging.204837 pp 5775—5797

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Comprehensive analysis of the prognostic and immunological signature of eight Tripartitemotif (TRIM) family molecules in human gliomas

Jiajie Lu, Kairong Liang, Renheng Zou, Yuecheng Peng, Haojian Wang, Rihong Huang, Zhaorong Zeng, Zejia Feng, Yongyang Fan, Shizhen Zhang, Yunxiang Ji, Xiao Pang, Yezhong Wang, Hongri Zhang, Zhaotao Wang,

https://doi.org/10.18632/aging.204841 pp 5798—5825

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Identification and validation of a 7-genes prognostic signature for adult acute myeloid leukemia based on aging-related genes

Peng Ke, Qian Zhu, Ting Xu, Xiaofei Yang, Ying Wang, Huiying Qiu, Depei Wu, Xiebing Bao, Suning Chen,

https://doi.org/10.18632/aging.204843 pp 5826—5853

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iPSC-derived exosomes promote angiogenesis in naturally aged mice

Xingyu Li, Heng Zhang, Xuemeng Wang, Meng Lu, Qianqian Ding, Alex F. Chen, Meng Xiang, Sifeng Chen,

https://doi.org/10.18632/aging.204845 pp 5854—5872

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Identification of prognosis value and immune microenvironment features of ceRNAs in NSCLC with distinct gene mutation

Jiangtao You, Qingshi Wang, Longlong Cong, Rui Zhao, Wei Cui, Huan Chen,

https://doi.org/10.18632/aging.204846 pp 5873—5886

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Swertia cincta Burkill alleviates LPS/D-GalN-induced acute liver failure by modulating apoptosis and oxidative stress signaling pathways

Xinyan Wu, Xiaomei Zheng, Qiqi Wen, Yang Zhang, Huaqiao Tang, Ling Zhao, Fei Shi, Yinglun Li, Zhongqiong Yin, Yuanfeng Zou, Xu Song, Lixia Li, Xinghong Zhao, Gang Ye,

https://doi.org/10.18632/aging.204848 pp 5887—5916

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Review

Shared biological mechanisms of depression and obesity: focus on adipokines and lipokines

Xiying Fu, Yicun Wang, Fangyi Zhao, Ranji Cui, Wei Xie, Qianqian Liu, Wei Yang,

https://doi.org/10.18632/aging.204847 pp 5917—5950

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Corrections

Correction for: Efficacy and safety of recombinant human follicle-stimulating hormone in patients undergoing in vitro fertilization-embryo transfer

Linli Hu, Songying Zhang, Song Quan, Jieqiang Lv, Weiping Qian, Yuanhua Huang, Weiying Lu, Yingpu Sun,

https://doi.org/10.18632/aging.204490 pp 5951—5953

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Correction for: Catalpol enhanced physical exercise-mediated brain functional improvement in post-traumatic stress disorder model via promoting adult hippocampal neurogenesis

Lina Sun, Weiwei Zhang, Ruiqi Ye, Lei Liu, Lili Jiang, Chao Xi,

https://doi.org/10.18632/aging.204873 pp 5954—5955

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