Volume 15, Issue 12

June 30, 2023pp 5230—5955

About the Cover

The cover features Figure 4 "Performance of age-predictive models built on various data types" from Salignon et al.

Editorials

Advancing screening for cognitive impairment: the memtrax continuous recognition test

J. Wesson Ashford, James O. Clifford, Michael F. Bergeron

https://doi.org/10.18632/aging.204828pp 5230—5231

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Advances in cancer therapy: clinical benefit of new cancer drugs

Daniel Tobias Michaeli, Julia Caroline Michaeli, Thomas Michaeli

https://doi.org/10.18632/aging.204839pp 5232—5234

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A seed and soil model of gut dysbiosis in Alzheimer’s disease

Chun-Che Hung, Kristi M. Crowe-White, Ian M. McDonough

https://doi.org/10.18632/aging.204840pp 5235—5237

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Could social relationships be key to reaching healthy longevity?

Antonio Garrido, Mónica De la Fuente

https://doi.org/10.18632/aging.204871pp 5238—5239

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Research Papers

Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis

Jérôme Salignon, Omid R. Faridani, Tasso Miliotis, Georges E. Janssens, Ping Chen, Bader Zarrouki, Rickard Sandberg, Pia Davidsson, Christian G. Riedel

https://doi.org/10.18632/aging.204787pp 5240—5265

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Hepatic hydrogen sulfide levels are reduced in mouse model of Hutchinson-Gilford progeria syndrome

Stephen E. Wilkie, Diana E. Marcu, Roderick N. Carter, Nicholas M. Morton, Susana Gonzalo, Colin Selman

https://doi.org/10.18632/aging.204835pp 5266—5278

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A novel peptide ‘T14’ reflects age and photo-aging in human skin

Sheila Rocha, Sara Garcia Ratés, Tumisang Moswete, Kristopher Kalleberg, Anna Villa, Jason P. Harcup, Susan A. Greenfield

https://doi.org/10.18632/aging.204844pp 5279—5289

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Neuroprotective effect of total flavonoids in stems and leaves of Glycyrrhiza uralensis Fisch. on oxidative stress in HT-22 cells and Caenorhabditis elegans

Weijia Chen, Lei He, Hongyan Pei, Jianming Li, Yan Zhao, Ying Zong, Hong Kan, Zhongmei He, Rui Du

https://doi.org/10.18632/aging.204627pp 5290—5303

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Construction and validation of a model based on immunogenic cell death-associated lncRNAs to predict prognosis and direct therapy for kidney renal clear cell carcinoma

Chenxi Cai, Kexin Shu, Wanying Chen, Jiatong Ding, Zishun Guo, Yiping Wei, Wenxiong Zhang

https://doi.org/10.18632/aging.204741pp 5304—5338

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Heterogeneity of tumor immune microenvironment in malignant and metastatic change in LUAD is revealed by single-cell RNA sequencing

Haiqiang Wang, Guoliang Han, Jiakuan Chen

https://doi.org/10.18632/aging.204752pp 5339—5354

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Construction and experimental validation of a B cell-related gene signature to predict the prognosis and immunotherapeutic sensitivity in bladder cancer

Ranran Zhou, Jiawei Zhou, Bahaerguli Muhuitijiang, Xiangbo Zeng, Wanlong Tan

https://doi.org/10.18632/aging.204753pp 5355—5380

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FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination

Songbai Liu, Peng Liu, Changhao Zhu, Rui Yang, Zhiwei He, Yongning Li, Ying Li, Xiaobin Fei, Junyi Hou, Xing Wang, Yaozhen Pan

https://doi.org/10.18632/aging.204780pp 5381—5398

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Comprehensive analysis reveals the involvement of hsa_circ_0037858/miR-5000-3p/FMR1 axis in malignant metastasis of clear cell renal cell carcinoma

Yuan Nianyong, Guowei Li

https://doi.org/10.18632/aging.204790pp 5399—5411

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Tumor-suppressive function and mechanism of miR-873-5p in glioblastoma: evidence based on bioinformatics analysis and experimental validation

Xiaobin Zhang, Fangkun Jing, Chen Guo, Xinning Li, Jianan Li, Guobiao Liang

https://doi.org/10.18632/aging.204800pp 5412—5425

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Chaetocin exhibits anticancer effects in esophageal squamous cell carcinoma via activation of Hippo pathway

Lin Li, Hangyu Jiang, Yuqi Li, Xiaochong Xiang, Yueming Chu, Jie Tang, Kang Liu, Danqun Huo, Xiaofen Zhang

https://doi.org/10.18632/aging.204801pp 5426—5444

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Cross-talk of RNA modification "writers" describes tumor stemness and microenvironment and guides personalized immunotherapy for gastric cancer

Zhuoqi Li, Xuehong Zhang, Wenjie Weng, Ge Zhang, Qianwen Ren, Yuan Tian

https://doi.org/10.18632/aging.204802pp 5445—5481

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Dissecting the alternation landscape of mitochondrial metabolism-related genes in lung adenocarcinoma and their latent mechanisms

Xing Jin, Di Liu, Demiao Kong, Xiaojiang Zhou, Liken Zheng, Chuan Xu

https://doi.org/10.18632/aging.204803pp 5482—5496

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Integrative analysis of single-cell and bulk RNA sequencing unveils the senescence landscape in ischemic stroke

Longhui Fu, Beibei Yu, Yongfeng Zhang, Shuai Cao, Boqiang Lv, Yunze Tian, Huangtao Chen, Shijie Yang, Yutian Hu, Jinghua Hua, Pengyu Ren, Jianzhong Li, Shouping Gong

https://doi.org/10.18632/aging.204804pp 5497—5513

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hucMSCs treatment prevents pulmonary fibrosis by reducing circANKRD42-YAP1-mediated mechanical stiffness

Haitong Zhang, Qi Zhu, Yunxia Ji, Meirong Wang, Qian Zhang, Weili Liu, Ruiqiong Li, Jinjin Zhang, Pan Xu, Xiaodong Song, Changjun Lv

https://doi.org/10.18632/aging.204805pp 5514—5534

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Galectin-1-mediated high NCAPG expression correlates with poor prognosis in gastric cancer

Tingrui Zheng, Tao Qian, Haihua Zhou, Zhiyi Cheng, Guiyuan Liu, Chuanjiang Huang, Rongrong Dou, Fuxing Liu, Xiaolan You

https://doi.org/10.18632/aging.204806pp 5535—5549

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Mettl3-mediated m⁶A modification plays a role in lipid metabolism disorders and progressive liver damage in mice by regulating lipid metabolism-related gene expression

Guanqi Dai, Shihao Huang, Yonglong Li, Xueyi Tu, Jiawei Xia, Zhihao Zhou, Wanyi Chen, Ao Zhang, Jintao Lin, Yingchun Li, Danhua He, Taoyan Lin, Jinge Cong, Ye Lei, Liuxin Han, Zhenxia Yao, Weiwei Liu, Ying Zhou, Qiwen Li, Jing Li, Yuqin Zhang, Aibing Wu, Dong Xiao, Wanshan Wang, Wentao Zhao, Junshuang Jia, Xiaolin Lin

https://doi.org/10.18632/aging.204810pp 5550—5568

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Expression, prognostic value and mechanism of SP100 family in pancreatic adenocarcinoma

Yunjie Duan, Yongxing Du, Yongrun Mu, Zongting Gu, Chengfeng Wang

https://doi.org/10.18632/aging.204811pp 5569—5591

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Significance of liquid-liquid phase separation (LLPS)-related genes in breast cancer: a multi-omics analysis

Jiaheng Xie, Liang Chen, Dan Wu, Shengxuan Liu, Shengbin Pei, Qikai Tang, Yue Wang, Mengmeng Ou, Zhechen Zhu, Shujie Ruan, Ming Wang, Jingping Shi

https://doi.org/10.18632/aging.204812pp 5592—5610

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Identifying the role of NUDCD1 in human tumors from clinical and molecular mechanisms: a study based on comprehensive bioinformatics and experimental validation

Bin Han, Jinsong He, Qing Chen, Min Yuan, Xi Zeng, Yuanting Li, Yan Zeng, Meibo He, Dan Feng, Daiyuan Ma

https://doi.org/10.18632/aging.204813pp 5611—5649

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Development and validation of a MUC16 mutation-associated immune prognostic model for lung adenocarcinoma

Honggang Liu, Tao Xin, Hongtao Duan, Yuanyong Wang, Changjian Shao, Yifang Zhu, Jiansheng Wang, Jianjun He

https://doi.org/10.18632/aging.204814pp 5650—5661

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Exploration of the effect of PUM1/Cripto-1 pathway on ferroptosis by regulating macrophage polarization in allogeneic blood transfused mice

Man-Di Wu, Yan Zhang, Huan Wang, Ke Yue, Yu Bai, Lai-Wei You, Ying-Hui Cui, Jian-Rong Guo

https://doi.org/10.18632/aging.204818pp 5662—5672

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DUSP10 is a novel immune-related biomarker connected with survival and cellular proliferation in lower-grade glioma

Feng Xiao, Hong Zhu, Yun Guo, Zhe Zhang, Gufeng Sun, Kai Huang, Hua Guo, Guowen Hu

https://doi.org/10.18632/aging.204821pp 5673—5697

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Sevoflurane upregulates neuron death process-related Ddit4 expression by NMDAR in the hippocampus

Shuai Li, Qi Hou, Runjia Wang, Yu Hou, Qiang Wang, Bo Zhang, Cheng Ni, Hui Zheng

https://doi.org/10.18632/aging.204822pp 5698—5712

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MAGOH is correlated with poor prognosis and is essential for cell proliferation in lower-grade glioma

Feng Xiao, Zhenli Long, Yun Guo, Hong Zhu, Zhe Zhang, Yao Xiao, Guowen Hu, Qing Yang, Kai Huang, Hua Guo

https://doi.org/10.18632/aging.204823pp 5713—5733

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lncSNHG3 drives breast cancer progression by epigenetically increasing CSNK2A1 expression level

Zhenlin Nie, Mu Xu, Linpeng Zhou, Bei Pan, Tao Xu, Bangshun He, Shukui Wang

https://doi.org/10.18632/aging.204824pp 5734—5750

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Construction of a T-cell exhaustion-related gene signature for predicting prognosis and immune response in hepatocellular carcinoma

Tianrui Kuang, Lilong Zhang, Dongqi Chai, Chen Chen, Weixing Wang

https://doi.org/10.18632/aging.204830pp 5751—5774

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Astaxanthin prevents osteoarthritis by blocking Rspo2-mediated Wnt/β-catenin signaling in chondrocytes and abolishing Rspo2-related inflammatory factors in macrophages

Chunhui Zhu, Gang Liu, Weiding Cui, Zhongjie Yu, Wei Chen, Yao Qin, Jiuxiang Liu, Yaojun Lu, Weimin Fan, Wenwei Liang

https://doi.org/10.18632/aging.204837pp 5775—5797

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Comprehensive analysis of the prognostic and immunological signature of eight Tripartitemotif (TRIM) family molecules in human gliomas

Jiajie Lu, Kairong Liang, Renheng Zou, Yuecheng Peng, Haojian Wang, Rihong Huang, Zhaorong Zeng, Zejia Feng, Yongyang Fan, Shizhen Zhang, Yunxiang Ji, Xiao Pang, Yezhong Wang, Hongri Zhang, Zhaotao Wang

https://doi.org/10.18632/aging.204841pp 5798—5825

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Identification and validation of a 7-genes prognostic signature for adult acute myeloid leukemia based on aging-related genes

Peng Ke, Qian Zhu, Ting Xu, Xiaofei Yang, Ying Wang, Huiying Qiu, Depei Wu, Xiebing Bao, Suning Chen

https://doi.org/10.18632/aging.204843pp 5826—5853

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iPSC-derived exosomes promote angiogenesis in naturally aged mice

Xingyu Li, Heng Zhang, Xuemeng Wang, Meng Lu, Qianqian Ding, Alex F. Chen, Meng Xiang, Sifeng Chen

https://doi.org/10.18632/aging.204845pp 5854—5872

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Identification of prognosis value and immune microenvironment features of ceRNAs in NSCLC with distinct gene mutation

Jiangtao You, Qingshi Wang, Longlong Cong, Rui Zhao, Wei Cui, Huan Chen

https://doi.org/10.18632/aging.204846pp 5873—5886

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Swertia cincta Burkill alleviates LPS/D-GalN-induced acute liver failure by modulating apoptosis and oxidative stress signaling pathways

Xinyan Wu, Xiaomei Zheng, Qiqi Wen, Yang Zhang, Huaqiao Tang, Ling Zhao, Fei Shi, Yinglun Li, Zhongqiong Yin, Yuanfeng Zou, Xu Song, Lixia Li, Xinghong Zhao, Gang Ye

https://doi.org/10.18632/aging.204848pp 5887—5916

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