Volume 4, Issue 10

October 2012pp 660—722

Editorials

Rapamycin as longevity enhancer and cancer preventative agent in the context of p53 deficiency

Lawrence A. Donehower

https://doi.org/10.18632/aging.100494pp 660—661

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Models of longevity (Calorie Restriction and AC5 KO): Result of three bad hypotheses

Stephen F. Vatner, Dorothy E. Vatner, Lin Yan

https://doi.org/10.18632/aging.100495pp 662—663

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Research Papers

Cystathionine beta synthase modulates senescence of human endothelial cells

Eva Albertini, Rafał Kozieł, Angela Dürr, Michael Neuhaus, Pidder Jansen-Dürr

https://doi.org/10.18632/aging.100491pp 664—673

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Coordination of DNA repair by NEIL1 and PARP-1: a possible link to aging

Nicole Noren Hooten, Megan Fitzpatrick, Kari Kompaniez, Kimberly D. Jacob, Brittany R. Moore, Julia Nagle, Janice Barnes, Althaf Lohani, Michele K. Evans

https://doi.org/10.18632/aging.100492pp 674—685

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The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats

Nataliya G. Kolosova, Natalia A. Stefanova, Natalia A. Muraleva, Vladimir P. Skulachev

https://doi.org/10.18632/aging.100493pp 686—694

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NF90 coordinately represses the senescence-associated secretory phenotype

Kumiko Tominaga-Yamanaka, Kotb Abdelmohsen, Jennifer L. Martindale, Xiaoling Yang, Dennis D. Taub, Myriam Gorospe

https://doi.org/10.18632/aging.100497pp 695—708

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Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

Elena A. Komarova, Marina P. Antoch, Liliya R. Novototskaya, Olga B. Chernova, Geraldine Paszkiewicz, Olga V. Leontieva, Mikhail V. Blagosklonny, Andrei V. Gudkov

https://doi.org/10.18632/aging.100498pp 709—714

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New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53^−/− mice by delaying carcinogenesis

Maria Comas, Ilia Toshkov, Karen K. Kuropatwinski, Olga B. Chernova, Alexander Polinsky, Mikhail V. Blagosklonny, Andrei V. Gudkov, Marina P. Antoch

https://doi.org/10.18632/aging.100496pp 715—722

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