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Volume 4, Issue 9

September 2012pp 578—659

Editorial

Complementary roles of mitochondrial respiration and ROS signaling on cellular aging and longevity

Antoni Barrientos

https://doi.org/10.18632/aging.100485pp 578—579

Research Papers

Low circulating IGF-I bioactivity is associated with human longevity: Findings in centenarians’ offspring

Giovanni Vitale, Michael P Brugts, Giulia Ogliari, Davide Castaldi, Letizia M. Fatti, Aimee J. Varewijck, Steven W. Lamberts, Daniela Monti, Laura Bucci, Elisa Cevenini, Francesco Cavagnini, Claudio Franceschi, Leo J Hofland, Daniela Mari, Joseph A.M.J.L. Janssen

https://doi.org/10.18632/aging.100484pp 580—589

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Plasma microRNA biomarkers for detection of mild cognitive impairment

Kira S. Sheinerman, Vladimir G. Tsivinsky, Fiona Crawford, Michael J. Mullan, Laila Abdullah, Samuil R. Umansky

https://doi.org/10.18632/aging.100486pp 590—605

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Aging induced decline in T-lymphopoiesis is primarily dependent on status of progenitor niches in the bone marrow and thymus

Liguang Sun, Robert Brown, Shande Chen, Qichuan Zhuge, Dong-Ming Su

https://doi.org/10.18632/aging.100487pp 606—619

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RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice

Ravindar R. Thomas, Shaharyar M. Khan, Rafal M. Smigrodzki, Isaac G. Onyango, Jameel Dennis, Omer M. Khan, Francisco R. Portell, James P. Bennett Jr.

https://doi.org/10.18632/aging.100488pp 620—635

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Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging

Alexandra Dallaire, Chantal Garand, Eric R. Paquet, Sarah J. Mitchell, Rafael de Cabo, Martin J. Simard, Michel Lebel

https://doi.org/10.18632/aging.100489pp 636—647

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Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity

Anshu Agrawal, Houfen Su, Justine Chen, Kathryn Osann, Sudhanshu Agrawal, Sudhir Gupta

https://doi.org/10.18632/aging.100490pp 648—659

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