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Page: 1234 of 4

• Research PaperVolume 13, Issue 21pp 24136-24154

  Mutations in DNA damage response pathways as a potential biomarker for immune checkpoint blockade efficacy: evidence from a seven-cancer immunotherapy cohort

  Relevance score: 0.00

  Wenjing Zhang, Liwen Zhang, Hao Jiang, Yuting Li, Suzhen Wang, Qinghua Wang

  Keywords: immunotherapy, DDR mutations, predictive biomarker, microenvironment, clinical practice

  Published in Aging on November 8, 2021

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• Research PaperVolume 12, Issue 1pp 808-824

  Low-abundance mutations in colorectal cancer patients and healthy adults

  Relevance score: 0.00

  Yanfei Li, Zhengsheng Dai, Gang Huang, Yueling Jin, Zhongping Ning, Junwei Shen

  Keywords: mutation, colorectal cancer, health, low-abundance

  Published in Aging on January 12, 2020

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• Research PaperVolume 8, Issue 11pp 2702-2712

  Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer

  Relevance score: 0.00

  Anton M.F. Kalsbeek, Eva F.K. Chan, Judith Grogan, Desiree C. Petersen, Weerachai Jaratlerdsiri, Ruta Gupta, Ruth J. Lyons, Anne-Maree Haynes, Lisa G. Horvath, James G. Kench, Phillip D. Stricker, Vanessa M. Hayes

  Keywords: prostate cancer, mitochondrial genome, prognostic biomarkers, mutational load

  Published in Aging on October 5, 2016

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• Research PaperVolume 15, Issue 23pp 13753-13775

  PBRM1 mutation and WDR72 expression as potential combinatorial biomarker for predicting the response to Nivolumab in patients with ccRCC: a tumor marker prognostic study

  Relevance score: 0.00

  Qinzheng Chang, Jiajia Sun, Shuo Zhao, Luchao Li, Nianzhao Zhang, Lei Yan, Yidong Fan, Jikai Liu

  Keywords: clear cell renal cell carcinoma, immune checkpoint therapy, PBRM1 mutation, Nivolumab, treg cell, WDR72

  Published in Aging on November 30, 2023

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• Research PaperVolume 15, Issue 19pp 10767-10784

  Modified iPOND revealed the role of mutant p53 in promoting helicase function and telomere maintenance

  Relevance score: 0.00

  Qianqian Wang, Kailong Hou, Jun Yang, Haili Li, Cui Li, Yanduo Zhang, Jie Tian, Chuanbiao Li, Bing Guo, Shuting Jia, Ying Luo

  Keywords: p53 mutation, DNA replication stress, DNA helicase, G-quadruplex structure, telomere

  Published in Aging on October 12, 2023

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• Research PaperVolume 15, Issue 15pp 7476-7495

  SETBP1 mutation determines sensitivity to immune checkpoint inhibitors in melanoma and NSCLC

  Relevance score: 0.00

  Fengxiao An, Wenjing Zhang, Yuxian Guo, Fuyan Shi, Yujia Kong, Liguo Tang, Caijing Han, Qinghua Wang

  Keywords: SETBP1 mutation, ICI treatment, melanoma, NSCLC, clinical biomarker

  Published in Aging on August 2, 2023

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• Research PaperVolume 13, Issue 22pp 24686-24709

  Genomic mutation features identify distinct BRCA-associated mutation characteristics in endometrioid carcinoma and endometrioid ovarian carcinoma

  Relevance score: 0.00

  Canhui Cao, Ruidi Yu, Wenjian Gong, Dan Liu, Xiaoxue Zhang, Yong Fang, Yu Xia, Wei Zhang, Qinglei Gao

  Keywords: endometrioid carcinoma, endometrioid ovarian carcinoma, genome mutation, BRCA, immune response

  Published in Aging on November 27, 2021

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• Research PaperVolume 13, Issue 6pp 8563-8587

  A novel panel based on immune infiltration and tumor mutational burden for prognostic prediction in hepatocellular carcinoma

  Relevance score: 0.00

  Chan Xie, Hewei Wu, Tao Pan, Xingrong Zheng, Xiaoan Yang, Genglin Zhang, Yunwen Lian, Jiaxin Lin, Liang Peng

  Keywords: tumor mutation burden, hepatocellular carcinoma, immune infiltration, neoplasm recurrence, vascular invasion

  Published in Aging on March 10, 2021

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• Research PaperVolume 13, Issue 1pp 750-768

  KRAS mutations are negatively correlated with immunity in colon cancer

  Relevance score: 0.00

  Xiaorui Fu, Xinyi Wang, Jinzhong Duanmu, Taiyuan Li, Qunguang Jiang

  Keywords: KRAS mutations, immunity, colon cancer, tumor-infiltrating immune cells, inflammation

  Published in Aging on November 26, 2020

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• Research PaperVolume 12, Issue 19pp 19316-19324

  SYNE1 mutation may enhance the response to immune checkpoint blockade therapy in clear cell renal cell carcinoma patients

  Relevance score: 0.00

  Pengju Li, Jeifei Xiao, Bangfen Zhou, Jinhuan Wei, Junhang Luo, Wei Chen

  Keywords: SYNE1 mutation, tumor mutation burden, immune response, immune cells infiltration

  Published in Aging on October 8, 2020

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• Research PaperVolume 12, Issue 18pp 17863-17894

  Epigenetic mutation load is weakly correlated with epigenetic age acceleration

  Relevance score: 0.00

  Qi Yan, Kimberly C. Paul, Ake T. Lu, Cynthia Kusters, Alexandra M. Binder, Steve Horvath, Beate Ritz

  Keywords: stochastic epigenetic mutation, epigenetic mutation load, aging, epigenetic clock, DNA methylation

  Published in Aging on September 29, 2020

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• Research PaperVolume 12, Issue 17pp 17288-17294

  Male patients with TERT mutation may be more likely to benefit from immunotherapy, especially for melanoma

  Relevance score: 0.00

  Jia Li, Zhaoyan Li, Chenyue Zhang, Chenxing Zhang, Haiyong Wang

  Keywords: sex disparity, TERT mutation, immunotherapy, melanoma

  Published in Aging on September 10, 2020

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• Research PaperVolume 12, Issue 11pp 10827-10843

  High mutation load, immune-activated microenvironment, favorable outcome, and better immunotherapeutic efficacy in melanoma patients harboring MUC16/CA125 mutations

  Relevance score: 0.00

  Qinghua Wang, Yichen Yang, Meng Yang, Xiangchun Li, Kexin Chen

  Keywords: MUC16, tumor mutation load, immune microenvironment, survival outcome, immunotherapeutic efficacy

  Published in Aging on June 3, 2020

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• Research PaperVolume 12, Issue 4pp 3140-3155

  Comparison of BRCA versus non-BRCA germline mutations and associated somatic mutation profiles in patients with unselected breast cancer

  Relevance score: 0.00

  Bo Chen, Guochun Zhang, Xuerui Li, Chongyang Ren, Yulei Wang, Kai Li, Hsiaopei Mok, Li Cao, Lingzhu Wen, Minghan Jia, Cheukfai Li, Liping Guo, Guangnan Wei, Jiali Lin, Yingzi Li, Yuchen Zhang, Han Han-Zhang, Jing Liu, Analyn Lizaso, Ning Liao

  Keywords: germline mutations, BRCA, non-BRCA, somatic mutations, breast cancer

  Published in Aging on February 24, 2020

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• Research PaperVolume 12, Issue 3pp 2132-2141

  EP300 mutation is associated with tumor mutation burden and promotes antitumor immunity in bladder cancer patients

  Relevance score: 0.00

  Gongmin Zhu, Lijiao Pei, Yuan Li, Xin Gou

  Keywords: bladder cancer, EP300, tumor mutation burden, tumor-infiltrating immune cells, prognosis

  Published in Aging on February 3, 2020

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• Research PaperVolume 12, Issue 2pp 1285-1303

  DNAH10 mutation correlates with cisplatin sensitivity and tumor mutation burden in small-cell lung cancer

  Relevance score: 0.00

  Man Li, Anqi Lin, Peng Luo, Weitao Shen, Dan Xiao, Lanying Gou, Jian Zhang, Linlang Guo

  Keywords: cisplatin, resistance, small cell lung cancer, DNAH10, tumor mutation burden

  Published in Aging on January 20, 2020

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• Research PaperVolume 12, Issue 1pp 756-766

  Germline mutation of TSC1 or TSC2 gene in Chinese patients with bilateral renal angiomyolipomas and mutation spectrum of Chinese TSC patients

  Relevance score: 0.00

  Wang Jiangyi, Guo Gang, Shi Guohai, Ye Dingwei

  Keywords: angiomyolipoma, tuberous sclerosis complex, mutation spectrum, gene test

  Published in Aging on January 12, 2020

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• EditorialVolume 9, Issue 1pp 3-4

  ESR1 mutations in breast cancer

  Relevance score: 0.00

  Florian Clatot, Laetitia Augusto, Frédéric Di Fiore

  Keywords: ESR1 mutations, breast cancer, circulating DNA

  Published in Aging on January 25, 2017

• Research PaperVolume 15, Issue 18pp 9759-9778

  Prognostic significance of CTNNB1 mutation in hepatocellular carcinoma: a systematic review and meta-analysis

  Relevance score: 0.00

  Genlin Lu, Jian Lin, Guoqiang Song, Min Chen

  Keywords: hepatocellular carcinoma, prognosis, CTNNB1, mutation, survival

  Published in Aging on September 20, 2023

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• Research PaperVolume 15, Issue 18pp 9743-9758

  NOTCH2 gene mutation and gamma-secretase inhibitor in mediating the malignancy of ovarian cancer

  Relevance score: 0.00

  Wenjing Wang, Ruiqian Liu, Wei Liao, Landie Ji, Jie Mei, Dan Su

  Keywords: ovarian cancer, cell malignancy, whole-exome sequencing, NOTCH2, mutation

  Published in Aging on September 19, 2023

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