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• Research PaperVolume 17, Issue 2pp 365-392

  Mitochondrial dysfunction, iron accumulation, lipid peroxidation, and inflammasome activation in cellular models derived from patients with multiple sclerosis

  Relevance score: 0.00

  Raquel García-Salas, Paula Cilleros-Holgado, Anna Di Spirito, David Gómez-Fernández, Rocío Piñero-Pérez, José Manuel Romero-Domínguez, Mónica Álvarez-Córdoba, Diana Reche-López, Ana Romero-González, Alejandra López-Cabrera, José Antonio Sánchez-Alcázar

  Keywords: multiple sclerosis, iron accumulation, lipid peroxidation, inflammasome, mitochondrial dysfunction

  Published in Aging on February 6, 2025

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• Research PaperVolume 11, Issue 21pp 9424-9441

  Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

  Relevance score: 0.00

  Chao Guo, Junrong Zhu, Jingwen Wang, Jialin Duan, Shanbo Ma, Ying Yin, Wei Quan, Wei Zhang, Yue Guan, Yi Ding, Aidong Wen, Yingdong Zhang

  Keywords: protocatechuic aldehyde, reactive oxygen species, mitochondrial dysfunction, Parkinson's disease, PLK2-Nrf2 pathway

  Published in Aging on November 6, 2019

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• Priority Research PaperVolume 10, Issue 8pp 1856-1866

  GRSF1 suppresses cell senescence

  Relevance score: 0.00

  Ji Heon Noh, Kyoung Mi Kim, M. Laura Idda, Jennifer L. Martindale, Xiaoling Yang, Kotb Abdelmohsen, Myriam Gorospe

  Keywords: mitochondrial dysfunction, cellular senescence, DNA damage response, IL6 secretion

  Published in Aging on August 7, 2018

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• Research PaperVolume 13, Issue 6pp 8421-8439

  PGC-1α alleviates mitochondrial dysfunction via TFEB-mediated autophagy in cisplatin-induced acute kidney injury

  Relevance score: 0.00

  Longhui Yuan, Yujia Yuan, Fei Liu, Lan Li, Jingping Liu, Younan Chen, Jingqiu Cheng, Yanrong Lu

  Keywords: PGC-1α, TFEB, autophagy, acute kidney injury, mitochondrial dysfunction

  Published in Aging on March 10, 2021

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• Research PaperVolume 12, Issue 1pp 193-203

  Interleukin-12p35 deficiency enhances mitochondrial dysfunction and aggravates cardiac remodeling in aging mice

  Relevance score: 0.00

  Jing Ye, Yuan Wang, Zhen Wang, Ling Liu, Zicong Yang, Di Ye, Menglong Wang, Yao Xu, Jishou Zhang, Mengmeng Zhao, Jianfang Liu, Yingzhong Lin, Qingwei Ji, Jun Wan

  Keywords: aging, cardiac remodeling, mitochondrial dysfunction, apoptosis-inducing factor, cardiomyocyte apoptosis

  Published in Aging on January 4, 2020

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• Research PaperVolume 11, Issue 10pp 3117-3137

  Exploration of age-related mitochondrial dysfunction and the anti-aging effects of resveratrol in zebrafish retina

  Relevance score: 0.00

  Ning Wang, Zhiwen Luo, Ming Jin, Weiwei Sheng, Han-Tsing Wang, Xinyi Long, Yue Wu, Piaopiao Hu, Hong Xu, Xu Zhang

  Keywords: aging zebrafish, retina, mitochondrial dysfunction, mitophagy, mTOR, resveratrol

  Published in Aging on May 19, 2019

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• Research PaperVolume 16, Issue 8pp 7141-7152

  Aberrant expression of thyroidal hormone receptor α exasperating mitochondrial dysfunction induced sarcopenia in aged mice

  Relevance score: 0.00

  Yunlu Sheng, Xiaoxia Zhu, Lijun Wei, Yuxin Zou, Xinyu Qi, Runqing Shi, Wenli Xu, Xiaodong Wang, Guoxian Ding, Yu Duan

  Keywords: thyroid hormone receptor α, mitochondrial dysfunction, mitophagy, skeletal muscles, aging mice

  Published in Aging on April 18, 2024

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• Research PaperVolume 12, Issue 4pp 3175-3189

  Ligustilide improves aging-induced memory deficit by regulating mitochondrial related inflammation in SAMP8 mice

  Relevance score: 0.00

  Wen-Li Zhu, Jia-Yi Zheng, Wei-Wu Cai, Zhao Dai, Ben-Yue Li, Ting-Ting Xu, Hao-Fei Liu, Xiao-Qi Liu, Su-Fen Wei, Yi Luo, Hong Wang, Hua-Feng Pan, Qi Wang, Shi-Jie Zhang

  Keywords: Alzheimer’s disease, ligustilide, SAMP8 mice, mitochondrial dysfunction, neuroinflammation

  Published in Aging on February 16, 2020

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• ReviewVolume 17, Issue 5pp 1340-1367

  Age-associated changes in the heart: implications for COVID-19 therapies

  Relevance score: 0.00

  Colby Wood, Wm. Zachary Salter, Isaiah Garcia, Michelle Nguyen, Andres Rios, Jacqui Oropeza, Destiny Ugwa, Upasana Mukherjee, Ujala Sehar, P. Hemachandra Reddy

  Keywords: cardiac aging, mitochondrial dysfunction, oxidative stress, COVID-19 cardiovascular complications, health disparities

  Published in Aging on May 13, 2025

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• Research PaperVolume 16, Issue 10pp 9264-9279

  Bufotalin enhances apoptosis and TMZ chemosensitivity of glioblastoma cells by promoting mitochondrial dysfunction via AKT signaling pathway

  Relevance score: 0.00

  Zhansheng Zhu, Shanwen Liang, Yu Hong, Yangzhi Qi, Qian Sun, Xinyi Zhu, Yuxin Wei, Yang Xu, Qianxue Chen

  Keywords: bufotalin, mitochondrial dysfunction, ROS, AKT, apoptosis, TMZ sensitivity

  Published in Aging on May 28, 2024

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• Research PaperVolume 16, Issue 4pp 3302-3331

  Exosomes as nanostructures deliver miR-204 in alleviation of mitochondrial dysfunction in diabetic nephropathy through suppressing methyltransferase-like 7A-mediated CIDEC N6-methyladenosine methylation

  Relevance score: 0.00

  Juan Jin, Yiwei Shang, Siqiang Zheng, Limiao Dai, Jiyu Tang, Xueyan Bian, Qiang He

  Keywords: diabetic nephropathy, exosome, microRNA-204, mitochondrial dysfunction, methyltransferase-like 7A

  Published in Aging on February 8, 2024

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• Research PaperVolume 12, Issue 8pp 7299-7312

  Melatonin improves mitochondrial biogenesis through the AMPK/PGC1α pathway to attenuate ischemia/reperfusion-induced myocardial damage

  Relevance score: 0.00

  Xueyan Qi, Jin Wang

  Keywords: melatonin, mitochondrial biogenesis, mitochondrial dysfunction, ischemia-reperfusion injury

  Published in Aging on April 19, 2020

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• Research PaperVolume 8, Issue 8pp 1718-1734

  Biological and biophysics aspects of metformin-induced effects: cortex mitochondrial dysfunction and promotion of toxic amyloid pre-fibrillar aggregates

  Relevance score: 0.00

  Pasquale Picone, Silvia Vilasi, Fabio Librizzi, Marco Contardi, Domenico Nuzzo, Luca Caruana, Sara Baldassano, Antonella Amato, Flavia Mulè, Pier Luigi San Biagio, Daniela Giacomazza, Marta Di Carlo

  Keywords: Alzheimer’s disease, metformin, mitochondrial dysfunction, cell degeneration, mitochondrial pores, β-amyloid aggregation

  Published in Aging on July 28, 2016

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• Research PaperVolume 16, Issue 3pp 2047-2060

  Disruption of mitochondrial unfolded protein response results in telomere shortening in mouse oocytes and somatic cells

  Relevance score: 0.00

  Mauro Cozzolino, Yagmur Ergun, Emma Ristori, Akanksha Garg, Gizem Imamoglu, Emre Seli

  Keywords: telomere length, aging, Clpp, mitochondrial dysfunction, unfolded protein response

  Published in Aging on February 12, 2024

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• Research PaperVolume 6, Issue 12pp 1094-1108

  Aged iPSCs display an uncommon mitochondrial appearance and fail to undergo in vitro neurogenesis

  Relevance score: 0.00

  Andrea Masotti, Antonella Celluzzi, Stefania Petrini, Enrico Bertini, Ginevra Zanni, Claudia Compagnucci

  Keywords: induced pluripotent stem cells, mitochondria, stem cell aging, mitochondrial dysfunction, in vitro neurogenesis

  Published in Aging on December 30, 2014

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• EditorialVolume 15, Issue 16pp 7863-7865

  Mitochondria: between aging, frailty and sarcopenia

  Relevance score: 0.00

  Annalisa Davin, Riccardo Rocco Ferrari, Orietta Pansarasa

  Keywords: frailty, sarcopenia, mitochondrial dysfunction, mtDNA, biomarkers

  Published in Aging on August 22, 2023

• CorrectionVolume 15, Issue 6pp 2358-2360

  Correction for: Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF

  Relevance score: 0.00

  Xiao-Lin Jiang, He Tai, Jin-Song Kuang, Jing-Yi Zhang, Shi-Chao Cui, Yu-Xuan Lu, Shu-Bo Qi, Shi-Yu Zhang, Shun-Min Li, Jian-Ping Chen, Xian-Sheng Meng

  Keywords: Jian-Pi-Yi-Shen, premature ovarian failure, mitochondrial dysfunction, granulosa cell, apoptosis

  Published in Aging on March 30, 2023

• Research PaperVolume 14, Issue 20pp 8321-8345

  Jian-Pi-Yi-Shen decoction inhibits mitochondria-dependent granulosa cell apoptosis in a rat model of POF

  Relevance score: 0.00

  Xiao-Lin Jiang, He Tai, Jin-Song Kuang, Jing-Yi Zhang, Shi-Chao Cui, Yu-Xuan Lu, Shu-Bo Qi, Shi-Yu Zhang, Shun-Min Li, Jian-Ping Chen, Xian-Sheng Meng

  Keywords: Jian-Pi-Yi-Shen, premature ovarian failure, mitochondrial dysfunction, granulosa cell, apoptosis

  Published in Aging on October 27, 2022

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• Research PaperVolume 12, Issue 7pp 6401-6414

  Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice

  Relevance score: 0.00

  Ting-Ting Xu, Han Li, Zhao Dai, George K. Lau, Ben-Yue Li, Wen-Li Zhu, Xiao-Qi Liu, Hao-Fei Liu, Wei-Wu Cai, Shui-Qing Huang, Qi Wang, Shi-Jie Zhang

  Keywords: polyamine, aging, mitochondrial dysfunction, autophagy

  Published in Aging on April 8, 2020

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• Research PaperVolume 11, Issue 2pp 448-466

  miRNA-mRNA crosstalk in myocardial ischemia induced by calcified aortic valve stenosis

  Relevance score: 0.00

  Chenyang Duan, Zhezhe Cao, Fuqin Tang, Zhao Jian, Chunshui Liang, Hong Liu, Yingbin Xiao, Liangming Liu, Ruiyan Ma

  Keywords: calcified aortic valve stenosis (CAVS), myocardial ischemia, mitochondrial dysfunction, hub genes, miRNA-mRNA crosstalk

  Published in Aging on January 16, 2019

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