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• Research PaperVolume 12, Issue 2pp 1397-1416

  Activated Drp1-mediated mitochondrial ROS influence the gut microbiome and intestinal barrier after hemorrhagic shock

  Relevance score: 0.00

  Chenyang Duan, Lei Kuang, Xinming Xiang, Jie Zhang, Yu Zhu, Yue Wu, Qingguang Yan, Liangming Liu, Tao Li

  Keywords: Drp1, mitochondrial ROS, SCFA, gut microbiome, intestinal barrier

  Published in Aging on January 18, 2020

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• Research PaperVolume 8, Issue 3pp 484-505

  MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4

  Relevance score: 0.00

  Alexander Lang, Susanne Grether-Beck, Madhurendra Singh, Fabian Kuck, Sascha Jakob, Andreas Kefalas, Simone Altinoluk-Hambüchen, Nina Graffmann, Maren Schneider, Antje Lindecke, Heidi Brenden, Ingo Felsner, Hakima Ezzahoini, Alessandra Marini, Sandra Weinhold, Andrea Vierkötter, Julia Tigges, Stephan Schmidt, Kai Stühler, Karl Köhrer, Markus Uhrberg, Judith Haendeler, Jean Krutmann, Roland P. Piekorz

  Keywords: MicroRNA-15b/miR-15b, nuclear encoded mitochondrial genes, photoaging, reactive oxygen species/ROS, senescence, senescence associated secretory phenotype/SASP, SIRT4/Sirtuin 4, skin

  Published in Aging on February 26, 2016

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• Research PaperVolume 9, Issue 10pp 2163-2189

  SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy

  Relevance score: 0.00

  Alexander Lang, Ruchika Anand, Simone Altinoluk-Hambüchen, Hakima Ezzahoini, Anja Stefanski, Afshin Iram, Laura Bergmann, Jennifer Urbach, Philip Böhler, Jan Hänsel, Manuel Franke, Kai Stühler, Jean Krutmann, Jürgen Scheller, Björn Stork, Andreas S. Reichert, Roland P. Piekorz

  Keywords: Sirtuin-4/SIRT4, mitochondrial quality control, mitochondrial fusion/fission, mitophagy, OPA1, reactive oxygen species/ROS, senescence, fibroblast, aging

  Published in Aging on October 29, 2017

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• Research PaperVolume 1, Issue 9pp 784-802

  Dermal fibroblasts from long-lived Ames dwarf mice maintain their in vivo resistance to mitochondrial generated reactive oxygen species (ROS)

  Relevance score: 0.00

  Ching-Chyuan Hsieh, John Papaconstantinou

  Keywords: dermal fibroblasts, mitochondrial ROS, rotenone, 3-nitropropionic acid, antimycin A, thioredoxin, ASK1, p38 MAPK, resistance to ROS, Ames dwarf mouse, aging

  Published in Aging on July 31, 2009

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• Research PaperVolume 16, Issue 9pp 8070-8085

  KLF4 inhibited the senescence-associated secretory phenotype in ox-LDL-treated endothelial cells via PDGFRA/NAMPT/mitochondrial ROS

  Relevance score: 0.00

  Haoran Ding, Jing Tong, Hao Lin, Fan Ping, Tongqing Yao, Zi Ye, Jiapeng Chu, Deqiang Yuan, Kangwei Wang, Xuebo Liu, Fei Chen

  Keywords: endothelial cells, SASP, KLF4, PDGFRA, NAMPT/mitochondrial ROS

  Published in Aging on May 8, 2024

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• Research PaperVolume 13, Issue 18pp 22588-22610

  GPR43 regulation of mitochondrial damage to alleviate inflammatory reaction in sepsis

  Relevance score: 0.00

  Weiwei Zhang, Wusan Wang, Maodi Xu, Haitang Xie, Zhichen Pu

  Keywords: GPR43, ROS, mitochondrial damage, NLRP3 inflammasome, PPARγ

  Published in Aging on September 28, 2021

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• Research PaperVolume 12, Issue 3pp 2275-2301

  PAS kinase deficiency reduces aging effects in mice

  Relevance score: 0.00

  Pilar Dongil, Ana Pérez-García, Verónica Hurtado-Carneiro, Carmen Herrero-de-Dios, Elvira Álvarez, Carmen Sanz

  Keywords: oxidative stress, mitochondrial function, antioxidant enzymes, liver regeneration, hepatic ROS

  Published in Aging on January 23, 2020

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• Priority Research PaperVolume 12, Issue 7pp 5590-5611

  Down-regulation of AMPK signaling pathway rescues hearing loss in TFB1 transgenic mice and delays age-related hearing loss

  Relevance score: 0.00

  Jingjing Zhao, Gen Li, Xuan Zhao, Xin Lin, Yunge Gao, Nuno Raimundo, Geng-Lin Li, Wei Shang, Hao Wu, Lei Song

  Keywords: mitochondrial deafness, ROS, AMPK, apoptosis, NIHL

  Published in Aging on April 2, 2020

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• Research PaperVolume 16, Issue 10pp 9264-9279

  Bufotalin enhances apoptosis and TMZ chemosensitivity of glioblastoma cells by promoting mitochondrial dysfunction via AKT signaling pathway

  Relevance score: 0.00

  Zhansheng Zhu, Shanwen Liang, Yu Hong, Yangzhi Qi, Qian Sun, Xinyi Zhu, Yuxin Wei, Yang Xu, Qianxue Chen

  Keywords: bufotalin, mitochondrial dysfunction, ROS, AKT, apoptosis, TMZ sensitivity

  Published in Aging on May 28, 2024

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• Research PaperVolume 12, Issue 10pp 8923-8938

  Influence of human amylin on the membrane stability of rat primary hippocampal neurons

  Relevance score: 0.00

  Nan Zhang, Yuan Xing, Yongzhou Yu, Chao Liu, Baohua Jin, Lifang Huo, Dezhi Kong, Zuxiao Yang, Xiangjian Zhang, Ruimao Zheng, Zhanfeng Jia, Lin Kang, Wei Zhang

  Keywords: hAmylin, hippocampal neurons, mitochondrial membrane potential (mtΔΨ), Integrity of plasma membrane, ROS

  Published in Aging on May 28, 2020

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• ReviewVolume 17, Issue 9pp 2430-2448

  Mitochondrial proteins as biomarkers of cellular senescence and age-associated diseases

  Relevance score: 0.00

  Anna Panfilova, Tatiana Zubareva, Ekaterina Mironova, Gianluigi Mazzoccoli, Maria Greta Pia Marasco, Sofya Balazovskaia, Peter Yablonsky, Igor Kvetnoy

  Keywords: mitochondria, mitochondrial proteins, biomarkers, cellular senescence, age-associated diseases

  Published in Aging on August 25, 2025

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• Research PaperVolume 17, Issue 2pp 365-392

  Mitochondrial dysfunction, iron accumulation, lipid peroxidation, and inflammasome activation in cellular models derived from patients with multiple sclerosis

  Relevance score: 0.00

  Raquel García-Salas, Paula Cilleros-Holgado, Anna Di Spirito, David Gómez-Fernández, Rocío Piñero-Pérez, José Manuel Romero-Domínguez, Mónica Álvarez-Córdoba, Diana Reche-López, Ana Romero-González, Alejandra López-Cabrera, José Antonio Sánchez-Alcázar

  Keywords: multiple sclerosis, iron accumulation, lipid peroxidation, inflammasome, mitochondrial dysfunction

  Published in Aging on February 6, 2025

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• Research PaperVolume 16, Issue 11pp 9649-9679

  A novel mitochondrial metabolism-related gene signature for predicting the prognosis of oesophageal squamous cell carcinoma

  Relevance score: 0.00

  Wenhao Lin, Changchun Ye, Liangzhang Sun, Zilu Chen, Chao Qu, Minxia Zhu, Jianzhong Li, Ranran Kong, Zhengshui Xu

  Keywords: mitochondrial metabolism, oesophageal squamous cell carcinoma, prognosis, nomogram

  Published in Aging on June 5, 2024

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• Research PaperVolume 16, Issue 8pp 7387-7404

  New insights from bidirectional Mendelian randomization: causal relationships between telomere length and mitochondrial DNA copy number in aging biomarkers

  Relevance score: 0.00

  Xinyu Yan, Peixuan Yang, Yani Li, Ting Liu, Yawen Zha, Ting Wang, Jingjing Zhang, Zhijun Feng, Minying Li

  Keywords: mitochondrial DNA copy number, causal relationship, telomere length, bidirectional two-sample Mendelian randomization

  Published in Aging on April 24, 2024

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• Research PaperVolume 15, Issue 19pp 10428-10452

  Mitochondrial dysfunction following repeated administration of alprazolam causes attenuation of hippocampus-dependent memory consolidation in mice

  Relevance score: 0.00

  Siqing Zhu, Jingjing Shi, Qian Jin, Yi Zhang, Ruihua Zhang, Xuejun Chen, Chen Wang, Tong Shi, Liqin Li

  Keywords: proteomics, alprazolam, repeated administration, mitochondrial damage, memory consolidation

  Published in Aging on October 5, 2023

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• Research PaperVolume 15, Issue 19pp 10347-10369

  Mitochondrial-related genes markers that predict survival in patients with head and neck squamous cell carcinoma affect immunomodulation through hypoxia, glycolysis, and angiogenesis pathways

  Relevance score: 0.00

  Zhonghua Li, Haoxi Cai, Jinyang Zheng, Xun Chen, Guancheng Liu, Yunxia Lv, Hui Ye, Gengming Cai

  Keywords: mitochondrial-related genes, head and neck squamous cell carcinoma, immunomodulation, risk score, prognostic model, predicting survival

  Published in Aging on October 4, 2023

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• EditorialVolume 15, Issue 13pp 5956-5958

  Mitochondrial fitness sustains healthy muscle aging

  Relevance score: 0.00

  Andrea Irazoki, Antonio Zorzano, David Sebastián

  Keywords: mitochondria, mitophagy, mitochondrial dynamics, aging, sarcopenia

  Published in Aging on June 24, 2023

• EditorialVolume 15, Issue 8pp 2817-2818

  Mitochondrial redox signaling: a key player in aging and disease

  Relevance score: 0.00

  Maria Vitale, Alberto Sanz, Filippo Scialò

  Keywords: mitochondrial reactive oxygen species, redox signaling, electron transport chain, reverse electron transport, mtROS propagation

  Published in Aging on April 10, 2023

• Research PaperVolume 14, Issue 22pp 8900-8913

  Denervation induces mitochondrial decline and exacerbates lysosome dysfunction in middle-aged mice

  Relevance score: 0.00

  Matthew Triolo, Debasmita Bhattacharya, David A. Hood

  Keywords: mitochondrial biogenesis, autophagy, mitophagy, lysosomes, muscle

  Published in Aging on November 4, 2022

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• EditorialVolume 12, Issue 17pp 16665-16666

  Mitochondrial oxidative phosphorylation is linked to T-cell exhaustion

  Relevance score: 0.00

  Shuai Jiang

  Keywords: mitochondrial oxidative phosphorylation, T cell exhaustion, NFAT, N-acetylcysteine

  Published in Aging on September 7, 2020