Aging
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Volume 8, Issue 3

March 2016pp 418—564

About the Cover

The cover for issue 3 of Aging features Figure 5, 'Expression of amyloid-β in mouse cochlear hair cells causes an early-onset auditory defect in high-frequency sound perception' from Omata et al.

Editorials

HIF repressors under chronic hypoxia

Weibo Luo, Yingfei Wang

https://doi.org/10.18632/aging.100922pp 418—419
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The double face of mitochondrial dysfunction

Dmitry Knorre, Anna Zyrina, Fedor Severin

https://doi.org/10.18632/aging.100923pp 420
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Genetics of renal cancer: focus on MTOR

Arindam P. Ghosh, Sunil Sudarshan

https://doi.org/10.18632/aging.100937pp 421—422
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Telomere length connects melanoma and glioma predispositions

Alyson A. Endicott, Jennie W. Taylor, Kyle M. Walsh

https://doi.org/10.18632/aging.100935pp 423—424
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Research Papers

Expression of amyloid-β in mouse cochlear hair cells causes an early-onset auditory defect in high-frequency sound perception

Yasuhiro Omata, Suganya Tharasegaran, Young-Mi Lim, Yasutoyo Yamasaki, Yasuhito Ishigaki, Takanori Tatsuno, Mitsuo Maruyama, Leo Tsuda

https://doi.org/10.18632/aging.100899pp 427—439
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Altered lipid metabolism in the aging kidney identified by three layered omic analysis

Fabian Braun, Markus M. Rinschen, Valerie Bartels, Peter Frommolt, Bianca Habermann, Jan H.J. Hoeijmakers, Björn Schumacher, Martijn E.T. Dollé, Roman-Ulrich Müller, Thomas Benzing, Bernhard Schermer, Christine E. Kurschat

https://doi.org/10.18632/aging.100900pp 441—454
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Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo−/− mice

Lucie Aumailley, Alessandra Warren, Chantal Garand, Marie Julie Dubois, Eric R. Paquet, David G. Le Couteur, André Marette, Victoria C. Cogger, Michel Lebel

https://doi.org/10.18632/aging.100902pp 458—483
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MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4

Alexander Lang, Susanne Grether-Beck, Madhurendra Singh, Fabian Kuck, Sascha Jakob, Andreas Kefalas, Simone Altinoluk-Hambüchen, Nina Graffmann, Maren Schneider, Antje Lindecke, Heidi Brenden, Ingo Felsner, Hakima Ezzahoini, Alessandra Marini, Sandra Weinhold, Andrea Vierkötter, Julia Tigges, Stephan Schmidt, Kai Stühler, Karl Köhrer, Markus Uhrberg, Judith Haendeler, Jean Krutmann, Roland P. Piekorz

https://doi.org/10.18632/aging.100905pp 484—505
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Centenarians’ offspring as a model of healthy aging: a reappraisal of the data on Italian subjects and a comprehensive overview

Laura Bucci, Rita Ostan, Elisa Cevenini, Elisa Pini, Maria Scurti, Giovanni Vitale, Daniela Mari, Calogero Caruso, Paolo Sansoni, Flaminia Fanelli, Renato Pasquali, Paola Gueresi, Claudio Franceschi, Daniela Monti

https://doi.org/10.18632/aging.100912pp 510—519
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Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid

Yuanyuan Li, Xing Yuan, Yunheng Shen, Jing Zhao, Rongcai Yue, Fang Liu, Weiwei He, Rui Wang, Lei Shan, Weidong Zhang

https://doi.org/10.18632/aging.100913pp 521—533
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Measuring aging rates of mice subjected to caloric restriction and genetic disruption of growth hormone signaling

Jacob J.E. Koopman, Diana van Heemst, David van Bodegom, Michael S. Bonkowski, Liou Y. Sun, Andrzej Bartke

https://doi.org/10.18632/aging.100919pp 539—546
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Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants

Luke C. Pilling, Janice L. Atkins, Kirsty Bowman, Samuel E. Jones, Jessica Tyrrell, Robin N. Beaumont, Katherine S. Ruth, Marcus A. Tuke, Hanieh Yaghootkar, Andrew R. Wood, Rachel M. Freathy, Anna Murray, Michael N. Weedon, Luting Xue, Kathryn Lunetta, Joanne M. Murabito, Lorna W. Harries, Jean-Marie Robine, Carol Brayne, George A. Kuchel, Luigi Ferrucci, Timothy M. Frayling, David Melzer

https://doi.org/10.18632/aging.100930pp 547—560
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Erratum

Erratum: Wound healing and longevity: Lessons from long-lived αMUPA mice

Hagai Yanai, Dimitri Toren, Klemens Vierlinger, Manuela Hofner, Christa Nöhammer, Marco Chilosi, Arie Budovsky, Vadim E Fraifeld

https://doi.org/10.18632/aging.100916pp 564
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