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• Priority Research PaperVolume 14, Issue 10pp 4195-4210

  Long-term treatment with chloroquine increases lifespan in middle-aged male mice possibly via autophagy modulation, proteasome inhibition and glycogen metabolism

  Relevance score: 0.00

  Thorsten R. Doeppner, Cristin Coman, Daiana Burdusel, Diana-Larisa Ancuta, Ulf Brockmeier, Daniel Nicolae Pirici, Kuang Yaoyun, Dirk M. Hermann, Aurel Popa-Wagner

  Keywords: chloroquine, longevity, middle-aged mice, toxicity, autophagy, proteasome

  Published in Aging on May 23, 2022

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• Research PaperVolume 15, Issue 6pp 1734-1747

  Selenium as a predictor of metabolic syndrome in middle age women

  Relevance score: 0.00

  Daria Schneider-Matyka, Anna Maria Cybulska, Małgorzata Szkup, Bogumiła Pilarczyk, Mariusz Panczyk, Agnieszka Tomza-Marciniak, Elżbieta Grochans

  Keywords: selenium, metabolic syndrome, PPAR-γ, middle aged women

  Published in Aging on March 21, 2023

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• Research PaperVolume 17, Issue 7pp 1868-1880

  Assessment of lipid parameters and its association with risk of stage 1 hypertension: a cohort study in middle-aged and elderly Chinese

  Relevance score: 0.00

  Jiabin Lin, Junyan Yu, Chulin Huang, Diaozhu Lin, Feng Li, Yiqin Qi, Ying Liang, Chuan Wang, Leiqin Cai, Yongfeng Huang, Wanting Feng, Na Li, Guojuan Lao, Huisheng Xiao, Chuan Yang, Li Yan, Meng Ren, Kan Sun

  Keywords: stage 1 hypertension, dyslipidemia, TG to HDL-C ratio, middle-aged and elderly Chinese, cohort study

  Published in Aging on July 14, 2025

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• Research PaperVolume 18, Issue 1pp 138-158

  Plant-based dietary patterns are associated with slower epigenetic aging

  Relevance score: 0.00

  Hyunju Kim, Christina A. Castellani, Jiantao Ma, Alexis C. Wood, Audrey Ting, Morgan E. Grams, Bing Yu, Kelly Ruggles, James S. Floyd, Dan E. Arking, Casey M. Rebholz

  Keywords: plant-based diets, DNA methylation, epigenetic aging, all-cause mortality, middle-aged adults

  Published in Aging on March 20, 2026

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• Research PaperVolume 14, Issue 19pp 8061-8076

  Higher platelet count, even within normal range, is associated with increased arterial stiffness in young and middle-aged adults

  Relevance score: 0.00

  Yu-Tsung Chou, Hung-Yu Chen, I-Hsuan Wu, Fei-Lin Su, Wen-Huang Li, Hung-Lung Hsu, Jui-Ting Tai, Ting-Hsing Chao

  Keywords: arterial stiffness, brachial-ankle pulse wave velocity, platelet count, mean platelet volume, middle-aged adult

  Published in Aging on October 14, 2022

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• Research PaperVolume 10, Issue 6pp 1206-1222

  The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese

  Relevance score: 0.00

  Xin Zhao, Xiaomin Liu, Aiping Zhang, Huashuai Chen, Qing Huo, Weiyang Li, Rui Ye, Zhihua Chen, Liping Liang, Qiong A. Liu, Juan Shen, Xin Jin, Wenwen Li, Marianne Nygaard, Xiao Liu, Yong Hou, Ting Ni, Lars Bolund, William Gottschalk, Wei Tao, Jun Gu, Xiao-Li Tian, Huanming Yang, Jian Wang, Xun Xu, Michael W. Lutz, Junxia Min, Yi Zeng, Chao Nie

  Keywords: copy number variation, longevity, Han Chinese, genome association study, long-lived, middle-aged controls

  Published in Aging on June 5, 2018

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• Research PaperVolume 13, Issue 16pp 20149-20163

  25-Hydroxycholesterol protecting from cerebral ischemia-reperfusion injury through the inhibition of STING activity

  Relevance score: 0.00

  Feihong Lin, Xinyu Yao, Chang Kong, Xia Liu, Zhangfan Zhao, Suhuan Rao, Lu Wang, Shan Li, Junlu Wang, Qinxue Dai

  Keywords: middle cerebral artery occlusion, 25-hydroxycholesterol, STING, autophagy, mTOR

  Published in Aging on August 18, 2021

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• Research PaperVolume 15, Issue 15pp 7844-7852

  Correlation of the middle cerebral artery atherosclerotic plaque characteristics with ischemic stroke recurrence: a vessel wall magnetic resonance imaging study

  Relevance score: 0.00

  Fangbing Li, Yilin Wang, Ying Du, Tianxiang Hu, Yejun Wu

  Keywords: vessel wall magnetic resonance imaging, atherosclerotic plaques, middle cerebral artery, ischemic stroke recurrence, plaque

  Published in Aging on August 10, 2023

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• Research PaperVolume 11, Issue 15pp 5518-5534

  Frailty in middle age is associated with frailty status and race-specific changes to the transcriptome

  Relevance score: 0.00

  Calais S. Prince, Nicole Noren Hooten, Nicolle A. Mode, Yongqing Zhang, Ngozi Ejiogu, Kevin G. Becker, Alan B. Zonderman, Michele K. Evans

  Keywords: frailty, race, gene expression, sequencing, health disparities, middle age

  Published in Aging on August 8, 2019

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• Research PaperVolume 12, Issue 6pp 5121-5139

  EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke

  Relevance score: 0.00

  Anthony Patrizz, Sarah J. Doran, Anjali Chauhan, Hilda Ahnstedt, Meaghan Roy-O’Reilly, Yun-Ju Lai, Gillian Weston, Sami Tarabishy, Anita R. Patel, Rajkumar Verma, Ilene Staff, Julia K. Kofler, Jun Li, Fudong Liu, Rodney M. Ritzel, Louise D. McCullough

  Keywords: stroke, middle cerebral artery occlusion, CD147, EMMPRIN, aging

  Published in Aging on March 19, 2020

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• Research PaperVolume 9, Issue 1pp 173-186

  Impaired fasting blood glucose is associated to cognitive impairment and cerebral atrophy in middle-aged non-human primates

  Relevance score: 0.00

  Fathia Djelti, Marc Dhenain, Jérémy Terrien, Jean-Luc Picq, Isabelle Hardy, Delphine Champeval, Martine Perret, Esther Schenker, Jacques Epelbaum, Fabienne Aujard

  Keywords: blood glucose, middle age, spatial memory performance, hippocampal/septal atrophy, spontaneous models, Microcebus murinus

  Published in Aging on December 28, 2016

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• Research PaperVolume 14, Issue 22pp 8944-8969

  JAK2/STAT3 pathway mediates neuroprotective and pro-angiogenic treatment effects of adult human neural stem cells in middle cerebral artery occlusion stroke animal models

  Relevance score: 0.00

  Geun-Hyoung Ha, Eun Ji Kim, Jee Soo Park, Ji Eun Kim, Hyun Nam, Je Young Yeon, Sun-Ho Lee, Kyunghoon Lee, Chung Kwon Kim, Kyeung Min Joo

  Keywords: adult human neural stem cells, middle cerebral artery occlusion, stroke, neuroprotection, pro-angiogenic effects

  Published in Aging on November 29, 2022

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• Research PaperVolume 16, Issue 4pp 3750-3762

  Suppression of cerebral ischemia injury induced blood brain barrier breakdown by dexmedetomidine via promoting CCN1

  Relevance score: 0.00

  Shuangmei Liu, Xuepeng Jia, Bo Liu, Yue Liu, Hong Yin

  Keywords: dexmedetomidine, cerebral ischemia injury, blood brain barrier, CCN1, middle cerebral artery occlusion

  Published in Aging on February 15, 2024

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• Research PaperVolume 8, Issue 5pp 1049-1060

  Ischemic stroke induces gut permeability and enhances bacterial translocation leading to sepsis in aged mice

  Relevance score: 0.00

  Joshua Crapser, Rodney Ritzel, Rajkumar Verma, Venugopal R. R. Venna, Fudong Liu, Anjali Chauhan, Edward Koellhoffer, Anita Patel, Austin Ricker, Kendra Maas, Joerg Graf, Louise D. D. McCullough

  Keywords: aging, inflammation, infection, experimental stroke, middle cerebral artery occlusion

  Published in Aging on April 25, 2016

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