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Page: 1234567 of 7

• Research PaperVolume 15, Issue 13pp 6073-6099

  Predicting lifespan-extending chemical compounds for C. elegans with machine learning and biologically interpretable features

  Relevance score: 0.00

  Caio Ribeiro, Christopher K. Farmer, João Pedro de Magalhães, Alex A. Freitas

  Keywords: lifespan-extension compounds, longevity drugs, machine learning, feature selection

  Published in Aging on July 13, 2023

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• Research PaperVolume 13, Issue 17pp 21040-21065

  Knock-down of odr-3 and ife-2 additively extends lifespan and healthspan in C. elegans

  Relevance score: 0.00

  Ioan Valentin Matei, Vimbai Netsai Charity Samukange, Gabriela Bunu, Dmitri Toren, Simona Ghenea, Robi Tacutu

  Keywords: lifespan extension, genetic interventions, synergism, ife-2, odr-3

  Published in Aging on September 9, 2021

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• Research PerspectiveVolume 2, Issue 4pp 238-243

  Protein kinase A is a target for aging and the aging heart

  Relevance score: 0.00

  Linda C Enns, Christina Pettan-Brewer, Warren Ladiges

  Keywords: lifespan extension, obesity resistance, enhanced cardiac function, mouse models of aging, AMPK, beta adrenergic receptors, leptin signaling

  Published in Aging on April 25, 2010

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• Research PaperVolume 7, Issue 1pp 1-13

  PCH-2 regulates Caenorhabditis elegans lifespan

  Relevance score: 0.00

  Hong Qian, Xiangru Xu, Laura E Niklason

  Keywords: longevity, lifespan extension, sirtuins, stressors, C. elegans

  Published in Aging on January 15, 2015

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• Priority Research PaperVolume 14, Issue 6pp 2442-2461

  Regulation of mTOR complexes in long-lived growth hormone receptor knockout and Snell dwarf mice

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  Xiaofang Shi, S. Joseph Endicott, Richard A. Miller

  Keywords: aging, lifespan extension, mTOR, TSC, growth hormone receptor

  Published in Aging on March 19, 2022

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• Research PaperVolume 7, Issue 3pp 152-166

  Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro

  Relevance score: 0.00

  Rafael de Cabo, Lijuan Liu, Ahmed Ali, Nathan Price, Jing Zhang, Mingyi Wang, Edward Lakatta, Pablo M. Irusta

  Keywords: human diploid fibroblasts, senescence, caloric restriction, lifespan extension, SIRT1, aging

  Published in Aging on January 13, 2015

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• Research PaperVolume 2, Issue 5pp 298-310

  Comparative transcriptional profiling identifies takeout as a gene that regulates life span

  Relevance score: 0.00

  Johannes Bauer, Michael Antosh, Chengyi Chang, Christoph Schorl, Santharam Kolli, Nicola Neretti, Stephen L. Helfand

  Keywords: Dietary restriction, Calorie restriction, microarrays, Drosophila melanogaster, Sir2, p53, Rpd3, Indy, methuselah (mth), chico, life span extension, and takeout

  Published in Aging on May 11, 2010

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• CorrectionVolume 17, Issue 11pp 2875-2875

  Correction for: Sex-specific longitudinal reversal of aging in old frail mice

  Relevance score: 0.00

  Cameron Kato, Jessica Zheng, Cindy Quang, Sophia Siopack, Joana Cruz, Zachery R. Robinson, Nicole Fong, Zhixin A. Zhang, Patrick Young, Michael J. Conboy, Irina M. Conboy

  Keywords: lifespan, healthspan, Alk5 inhibitor, oxytocin, sex-specific differences

  Published in Aging on November 30, 2025

• Research PaperVolume 17, Issue 10pp 2500-2533

  The role of phenylalanine and tyrosine in longevity: a cohort and Mendelian randomization study

  Relevance score: 0.00

  Jie V. Zhao, Yitang Sun, Junmeng Zhang, Kaixiong Ye

  Keywords: lifespan, phenylalanine, tyrosine, mendelian randomization, sex-specific

  Published in Aging on October 3, 2025

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• Research PaperVolume 17, Issue 9pp 2252-2277

  Sex-specific longitudinal reversal of aging in old frail mice

  Relevance score: 0.00

  Cameron Kato, Jessica Zheng, Cindy Quang, Sophia Siopack, Joana Cruz, Zachery R. Robinson, Nicole Fong, Zhixin A. Zhang, Patrick Young, Michael J. Conboy, Irina M. Conboy

  Keywords: lifespan, healthspan, Alk5 inhibitor, oxytocin, sex-specific differences

  Published in Aging on August 21, 2025

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• Research PaperVolume 16, Issue 18pp 12443-12472

  Single housing of juveniles accelerates early-stage growth but extends adult lifespan in African turquoise killifish

  Relevance score: 0.00

  Chika Takahashi, Emiko Okabe, Masanori Nono, Saya Kishimoto, Hideaki Matsui, Tohru Ishitani, Takuya Yamamoto, Masaharu Uno, Eisuke Nishida

  Keywords: lifespan, aging, growth, housing density, African turquoise killifish

  Published in Aging on September 16, 2024

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• Research PaperVolume 15, Issue 10pp 3967-3983

  Vascular endothelial growth factor receptor 1 gene (FLT1) longevity variant increases lifespan by reducing mortality risk posed by hypertension

  Relevance score: 0.00

  Brian J. Morris, Randi Chen, Timothy A. Donlon, Kalpana J. Kallianpur, Kamal H. Masaki, Bradley J. Willcox

  Keywords: lifespan, genetics, hypertension, coronary heart disease, diabetes

  Published in Aging on May 12, 2023

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• Research PaperVolume 14, Issue 17pp 7065-7092

  The general law of plasma proteome alterations occurring in the lifetime of Chinese individuals reveals the importance of immunity

  Relevance score: 0.00

  Xiaolin Ni, Juan Jiao, Ze Yang, Zhaoping Wang, Nan Nan, Danni Gao, Liang Sun, Xiaoquan Zhu, Qi Zhou, Nan Zhang, Zhu Wu, Shenqi Zhang, Huiping Yuan

  Keywords: lifespan, proteomics, biological processes, immune system, aging

  Published in Aging on September 7, 2022

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• Research PaperVolume 14, Issue 16pp 6427-6448

  An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis

  Relevance score: 0.00

  Navid Tahanzadeh, Mirjam Knop, Yvonne Seidler, Sebastian Dirndorfer, Kai Lürsen, Iris Bruchhaus, Roman Lang, Gerald Rimbach, Thomas Roeder

  Keywords: lifespan, alga, Tor, sex-specific

  Published in Aging on August 16, 2022

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• Research PaperVolume 13, Issue 6pp 7953-7974

  Lifespan extension conferred by mitogen-activated protein kinase kinase kinase 5 (MAP3K5) longevity-associated gene variation is confined to at-risk men with a cardiometabolic disease

  Relevance score: 0.00

  Brian J. Morris, Randi Chen, Timothy A. Donlon, Kamal H. Masaki, D. Craig Willcox, Richard C. Allsopp, Bradley J. Willcox

  Keywords: lifespan, genetics, diabetes, hypertension, coronary heart disease

  Published in Aging on March 19, 2021

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• Research PaperVolume 11, Issue 18pp 7746-7779

  Inadequate control of thyroid hormones sensitizes to hepatocarcinogenesis and unhealthy aging

  Relevance score: 0.00

  Livia López-Noriega, Vivian Capilla-González, Nadia Cobo-Vuilleumier, Eugenia Martin-Vazquez, Petra Isabel Lorenzo, Enrique Martinez-Force, Mario Soriano-Navarro, María García-Fernández, Silvana Yanina Romero-Zerbo, Francisco Javier Bermúdez-Silva, Irene Díaz-Contreras, Ana Sánchez-Cuesta, Carlos Santos-Ocaña, Abdelkrim Hmadcha, Bernat Soria, Franz Martín, Benoit Raymond Gauthier, Alejandro Martin-Montalvo

  Keywords: lifespan, healthspan, thyroid hormones, hyperthyroidism, hypothyroidism, glucose metabolism

  Published in Aging on September 13, 2019

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• Research PaperVolume 11, Issue 13pp 4611-4640

  The role of commensal microbes in the lifespan of Drosophila melanogaster

  Relevance score: 0.00

  Hye-Yeon Lee, Shin-Hae Lee, Ji-Hyeon Lee, Won-Jae Lee, Kyung-Jin Min

  Keywords: lifespan, commensal microbe, abundance, composition, Drosophila melanogaster

  Published in Aging on July 12, 2019

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• Research PaperVolume 8, Issue 10pp 2370-2391

  A cross-sectional study of male and female C57BL/6Nia mice suggests lifespan and healthspan are not necessarily correlated

  Relevance score: 0.00

  Kathleen E. Fischer, Jessica M. Hoffman, Lauren B. Sloane, Jonathan A.L. Gelfond, Vanessa Y. Soto, Arlan G. Richardson, Steven N. Austad

  Keywords: healthspan, lifespan, physiological function, aging, longevity, sex differences

  Published in Aging on October 2, 2016

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• Research PaperVolume 7, Issue 2pp 133-143

  Distinct regulation of Maf1 for lifespan extension by Protein kinase A and Sch9

  Relevance score: 0.00

  Ying Cai, Yue-Hua Wei

  Keywords: lifespan, yeast, Protein Kinase A (PKA), Sch9, Maf1

  Published in Aging on February 22, 2015

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• Research PaperVolume 6, Issue 12pp 1076-1093

  Embryonic expression of shuttle craft, a Drosophila gene involved in neuron development, is associated with adult lifespan

  Relevance score: 0.00

  Natalia V. Roshina, Alexander V. Symonenko, Anna V. Krementsova, Mikhail V. Trostnikov, Elena G. Pasyukova

  Keywords: lifespan, aging, embryonic gene expression, locomotion, reproduction, synaptic function, Drosophila melanogaster

  Published in Aging on December 28, 2014

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