Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

Volume 14, Issue 16

31 August, 2022
pp 6379—6841

About the Cover

The cover features Figure 1 "Scheme of the experimental setup and data analysis" from Rysanek et al.

Explore This Issue

Editorial

Looking at IGF-1 through the hourglass

William B. Zhang, Sofiya Milman,

https://doi.org/10.18632/aging.204257 pp 6379—6380

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Research Papers

Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells

David Rysanek, Pavla Vasicova, Jayaprakash Narayana Kolla, David Sedlak, Ladislav Andera, Jiri Bartek, Zdenek Hodny,

https://doi.org/10.18632/aging.204207 pp 6381—6414

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Heritability of R2* iron in the basal ganglia and cortex

Edith Hofer, Lukas Pirpamer, Christian Langkammer, Christian Tinauer, Sudha Seshadri, Helena Schmidt, Reinhold Schmidt,

https://doi.org/10.18632/aging.204212 pp 6415—6426

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An aqueous extract of the brown alga Eisenia bicyclis extends lifespan in a sex-specific manner by interfering with the Tor-FoxO axis

Navid Tahanzadeh, Mirjam Knop, Yvonne Seidler, Sebastian Dirndorfer, Kai Lürsen, Iris Bruchhaus, Roman Lang, Gerald Rimbach, Thomas Roeder,

https://doi.org/10.18632/aging.204218 pp 6427—6448

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Fecal microbiota transplantation can improve cognition in patients with cognitive decline and Clostridioides difficile infection

Soo-Hyun Park, Jung-Hwan Lee, Jun-Seob Kim, Tae Jung Kim, Jongbeom Shin, Jae Hyoung Im, Boram Cha, Suhjoon Lee, Kye Sook Kwon, Yong Woon Shin, Sang-Bae Ko, Seong Hye Choi,

https://doi.org/10.18632/aging.204230 pp 6449—6466

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Effect of BBT-877, a novel inhibitor of ATX, on a mouse model of type 1 diabetic nephropathy

Jong Han Lee, Phyu Phyu Khin, GwangHee Lee, Oh Kyung Lim, Hee-Sook Jun,

https://doi.org/10.18632/aging.204249 pp 6467—6480

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Systemic lipolysis promotes physiological fitness in Drosophila melanogaster

Linshan Shang, Elizabeth Aughey, Huiseon Kim, Timothy D. Heden, Lu Wang, Charles P. Najt, Nicholas Esch, Sophia Brunko, Juan E. Abrahante, Marissa Macchietto, Mara T. Mashek, Todd Fairbanks, Daniel E. L. Promislow, Thomas P. Neufeld, Douglas G. Mashek,

https://doi.org/10.18632/aging.204251 pp 6481—6506

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miR-141 exacerbates lung ischemia-reperfusion injury by targeting EGFR/β-catenin axis-mediated autophagy

Miao Yang, Xiaomei Ling, Jinfang Xiao,

https://doi.org/10.18632/aging.204137 pp 6507—6519

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Dicer-mediated miR-200b expression contributes to cell migratory/invasive abilities and cancer stem cells properties of breast cancer cells

Tung-Wei Hsu, Hsin-An Chen,, Po-Hsiang Liao, Yen-Hao Su, Ching-Feng Chiu, Chih-Yang Huang, Yu-Jung Lin, Chih-Chiang Hung, Ming-Hsin Yeh, Shian-Ying Sung, Chih-Ming Su,

https://doi.org/10.18632/aging.204205 pp 6520—6536

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Alterations of gut viral signals in atrial fibrillation: complex linkage with gut bacteriome

Kun Zuo, Jing Li, Chen Fang, Jiuchang Zhong, Li Xu, Xinchun Yang,

https://doi.org/10.18632/aging.204222 pp 6537—6553

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Distinct microglia alternative splicing in Alzheimer's disease

Yanjun Lu, Lu Tan, Jiazhao Xie, Liming Cheng, Xiong Wang,

https://doi.org/10.18632/aging.204223 pp 6554—6566

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Correlation of the systemic immune-inflammation index with short- and long-term prognosis after acute ischemic stroke

Nan Wang, Yingying Yang, Baoshan Qiu, Ying Gao, Anxin Wang, Qin Xu, Xia Meng, Yuming Xu, Bo Song, Yongjun Wang, Yilong Wang,

https://doi.org/10.18632/aging.204228 pp 6567—6578

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ALKBH family members as novel biomarkers and prognostic factors in human breast cancer

Hongxi Chen, Lei Zhou, Juanni Li, Kuan Hu,

https://doi.org/10.18632/aging.204231 pp 6579—6593

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MiR-375 mitigates retinal angiogenesis by depressing the JAK2/STAT3 pathway

Ruowen Gong, Ruyi Han, Xiaonan Zhuang, Wenyi Tang, Gezhi Xu, Lei Zhang, Jihong Wu, Jun Ma,

https://doi.org/10.18632/aging.204232 pp 6594—6604

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Transcriptomic signature associated with RNA-binding proteins for survival stratification of laryngeal cancer

Yujie Shen, Huijun Chen, Qiang Huang, Huaidong Du, Liang Zhou,

https://doi.org/10.18632/aging.204234 pp 6605—6625

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Oxypeucedanin relieves LPS-induced acute lung injury by inhibiting the inflammation and maintaining the integrity of the lung air-blood barrier

Li Du, Jinrong Zhang, Xiyue Zhang, Chunyan Li, Qi Wang, Guangping Meng, Xingchi Kan, Jie Zhang, Yuxi Jia,

https://doi.org/10.18632/aging.204235 pp 6626—6641

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Rhein promotes TRAIL-induced apoptosis in bladder cancer cells by up-regulating DR5 expression

Liang Ma, Hong-Ling Wei, Ke-Jie Wang, Xiang-Yu Meng, Sai-Qi Ni, Cheng Zhou, Yi Li, Rui Yu, Qi Ma,

https://doi.org/10.18632/aging.204236 pp 6642—6655

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Gene expression profile of human colorectal cancer identified NKTR as a biomarker for liver metastasis

Rui Bai, Zhong Shi, Dan Li, Donger Zhou, Wei-Ting Ge, Shu Zheng,

https://doi.org/10.18632/aging.204242 pp 6656—6667

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MicroRNA-148a induces apoptosis and prevents angiogenesis with bevacizumab in colon cancer through direct inhibition of ROCK1/c-Met via HIF-1α under hypoxia

Hsiang-Lin Tsai, Yueh-Chiao Tsai, Yen-Cheng Chen, Ching-Wen Huang, Po-Jung Chen, Ching-Chun Li, Wei-Chih Su, Tsung-Kun Chang, Yung-Sung Yeh, Tzu-Chieh Yin, Jaw-Yuan Wang,

https://doi.org/10.18632/aging.204243 pp 6668—6688

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Prognostic alternative splicing events related splicing factors define the tumor microenvironment and pharmacogenomic landscape in lung adenocarcinoma

Jichang Liu, Yadong Wang, Xiaogang Zhao, Kai Wang, Chao Wang, Jiajun Du,

https://doi.org/10.18632/aging.204244 pp 6689—6715

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Psoralen downregulates osteoarthritis chondrocyte inflammation via an estrogen-like effect and attenuates osteoarthritis

Kui Huang, Bo Wu, Zhuhu Hou, Akhlaq Ahmad, Mushtaq Ahmed, Ayesha Ali Khan, Feng Tian, Fan Cheng, Wei Chu, Ke Deng,

https://doi.org/10.18632/aging.204245 pp 6716—6726

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Induction versus adjuvant chemotherapy combined with concurrent chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma: a retrospective cohort study

Xiaoli Mu, Hongyan Liu, Juan Wu, Shi Chen, Xingchen Peng, Jingjing Wang, Zhigong Wei, Ling He, Jiyan Liu, Zejun Lu, Yonglin Su,

https://doi.org/10.18632/aging.204246 pp 6727—6739

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Sulforaphane inhibits angiotensin II-induced cardiomyocyte apoptosis by acetylation modification of Nrf2

Huanhuan Wang, Ge Yang, Yuan Tian, Jinjie Li, Lingbin Meng, Xin Jiang, Ying Xin,

https://doi.org/10.18632/aging.204247 pp 6740—6755

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The risk of developing second primary malignancies among colorectal cancer patients

Songtao Du, Yayun Li, Huiyan Sun, Guangtong Deng, Siyuan Tang, Furong Zeng, Bomiao Zhang, Binbin Cui,

https://doi.org/10.18632/aging.204250 pp 6756—6779

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High expression of CCNB1 driven by ncRNAs is associated with a poor prognosis and tumor immune infiltration in breast cancer

Hongtao Fu, Kun Li, Shui Wang, Yuming Li,

https://doi.org/10.18632/aging.204253 pp 6780—6795

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MiR-217-5p inhibits smog (PM2.5)-induced inflammation and oxidative stress response of mouse lung tissues and macrophages through targeting STAT1

Jianli Xie, Shaohua Li, Xiaoning Ma, Rongqin Li, Huiran Zhang, Jingwen Li, Xixin Yan,

https://doi.org/10.18632/aging.204254 pp 6796—6808

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LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis

Sixuan Wang, Jun Duan, Jiangquan Liao, Yan Wang, Xiang Xiao, Lin Li, Yi Liu, Huan Gu, Peng Yang, Dongliang Fu, Jinhang Du, Xianlun Li, Mingjing Shao,

https://doi.org/10.18632/aging.204256 pp 6809—6828

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Review

New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

Tomas Schmauck-Medina, Adrian Molière, Sofie Lautrup, Jianying Zhang, Stefan Chlopicki, Helena Borland Madsen, Shuqin Cao, Casper Soendenbroe, Els Mansell, Mark Bitsch Vestergaard, Zhiquan Li, Yosef Shiloh, Patricia L. Opresko, Jean-Marc Egly, Thomas Kirkwood, Eric Verdin, Vilhelm A. Bohr, Lynne S. Cox, Tinna Stevnsner, Lene Juel Rasmussen, Evandro F. Fang,

https://doi.org/10.18632/aging.204248 pp 6829—6839

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Correction

Correction for: Characterization of the expression and prognostic value of 14-3-3 isoforms in breast cancer

Jie Mei, Yan Liu, Rui Xu, Leiyu Hao, An Qin, Chunqiang Chu, Yichao Zhu, Xiao Liu,

https://doi.org/10.18632/aging.204272 pp 6840—6841

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