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Page: 12 of 2

• Research PaperVolume 14, Issue 4pp 1651-1664

  Mitochondrial dysfunction in mandibular hypoplasia, deafness and progeroid features with concomitant lipodystrophy (MDPL) patients

  Relevance score: 0.00

  Michela Murdocca, Paola Spitalieri, Angela Cappello, Fiorella Colasuonno, Sandra Moreno, Eleonora Candi, Maria Rosaria D'Apice, Giuseppe Novelli, Federica Sangiuolo

  Keywords: premature aging syndrome, MDPL syndrome, mitochondria, SOD2, ROS production, metformin, autophagy, FIB/SEM

  Published in Aging on February 23, 2022

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• Research PaperVolume 18, Issue 1pp 234-260

  A manually curated gene–phenotype catalogue for progeroid syndromes and premature aging

  Relevance score: 0.00

  Nuša Likar, Tanja Kunej

  Keywords: aging, premature aging, progeroid syndromes, DNA repair, LMNA gene

  Published in Aging on March 30, 2026

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• Research PaperVolume 3, Issue 4pp 417-429

  Accelerated in vivo epidermal telomere loss in Werner syndrome

  Relevance score: 0.00

  Naoshi Ishikawa, Ken-Ichi Nakamura, Naotaka Izumiyama-Shimomura, Junko Aida, Akio Ishii, Makoto Goto, Yuichi Ishikawa, Reimi Asaka, Masaaki Matsuura, Atsushi Hatamochi, Mie Kuroiwa, Kaiyo Takubo

  Keywords: telomere, terminal restriction fragment, Werner syndrome, WRN helicase, skin, muscle, premature aging, segmental progeroid syndrome

  Published in Aging on April 25, 2011

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• EditorialVolume 15, Issue 15pp 7336-7337

  Insights into aging from progeroid syndrome epigenetics

  Relevance score: 0.00

  Yosra Bejaoui, Junko Oshima, Nady El Hajj

  Keywords: premature aging, epigenetics, progeroid syndromes, epigenetic clocks, DNA methylation

  Published in Aging on August 5, 2023

• EditorialVolume 12, Issue 3pp 2022-2023

  Lessons for aging from Werner syndrome epigenetics

  Relevance score: 0.00

  George M. Martin, Martin Poot, Thomas Haaf

  Keywords: premature aging, developmental origins, epigenetic changes, transcriptional disease, Werner syndrome

  Published in Aging on February 5, 2020

• Research PaperVolume 18, Issue 1pp 262-281

  Modeling premature aging in yeast via the expression of Progerin

  Relevance score: 0.00

  Zachery R. Belak, Christopher Ptak, Rachel E. Harris, Rick Wozniak, Christopher H. Eskiw, Troy AA. Harkness

  Keywords: Hutchinson-Gilford Progeria Syndrome, yeast, Progerin, Lamin A, premature aging

  Published in Aging on April 3, 2026

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• Research PaperVolume 15, Issue 19pp 9948-9964

  Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome

  Relevance score: 0.00

  Daisuke Sawada, Hisaya Kato, Hiyori Kaneko, Daisuke Kinoshita, Shinichiro Funayama, Takuya Minamizuka, Atsushi Takasaki, Katsushi Igarashi, Masaya Koshizaka, Aki Takada-Watanabe, Rito Nakamura, Kazuto Aono, Ayano Yamaguchi, Naoya Teramoto, Yukari Maeda, Tomohiro Ohno, Aiko Hayashi, Kana Ide, Shintaro Ide, Mayumi Shoji, Takumi Kitamoto, Yusuke Endo, Hideyuki Ogata, Yoshitaka Kubota, Nobuyuki Mitsukawa, Atsushi Iwama, Yasuo Ouchi, Naoya Takayama, Koji Eto, Katsunori Fujii, Tomozumi Takatani, Tadashi Shiohama, Hiromichi Hamada, Yoshiro Maezawa, Koutaro Yokote

  Keywords: Werner syndrome, premature aging, lipodystrophy, stromal vascular fraction, SASP

  Published in Aging on October 3, 2023

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• ReviewVolume 1, Issue 1pp 28-37

  Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A

  Relevance score: 0.00

  Phillip R. Musich, Yue Zou

  Keywords: Lamin A, Hutchinson-Gilford progeria syndrome, premature aging, Genome instability, DNA damage responses, XPA, DNA double strand breaks, DNA repair

  Published in Aging on January 16, 2009

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• Research PaperVolume 17, Issue 4pp 937-959

  Decreased mitochondrial NAD+ in WRN deficient cells links to dysfunctional proliferation

  Relevance score: 0.00

  Sofie Lautrup, Shi-Qi Zhang, Shinichiro Funayama, Lisa Lirussi, Tina Visnovska, Hoi-Hung Cheung, Marc Niere, Yuyao Tian, Hilde Loge Nilsen, Geir Selbæk, Janna Saarela, Yoshiro Maezawa, Koutaro Yokote, Per Nilsson, Wai-Yee Chan, Hisaya Kato, Mathias Ziegler, Vilhelm A. Bohr, Evandro F. Fang

  Keywords: Werner syndrome, premature aging, NAD+, mitochondria, proliferation

  Published in Aging on April 2, 2025

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• Research PaperVolume 12, Issue 24pp 24940-24956

  Time gap between the onset and diagnosis in Werner syndrome: a nationwide survey and the 2020 registry in Japan

  Relevance score: 0.00

  Masaya Koshizaka, Yoshiro Maezawa, Yukari Maeda, Mayumi Shoji, Hisaya Kato, Hiyori Kaneko, Takahiro Ishikawa, Daisuke Kinoshita, Kazuki Kobayashi, Junji Kawashima, Akiko Sekiguchi, Sei-ichiro Motegi, Hironori Nakagami, Yoshihiko Yamada, Shinji Tsukamoto, Akira Taniguchi, Ken Sugimoto, Yukiko Shoda, Kunihiko Hashimoto, Toru Yoshimura, Daisuke Suzuki, Masafumi Kuzuya, Minoru Takemoto, Koutaro Yokote

  Keywords: Werner syndrome, registry, nationwide survey, premature aging, sarcopenia

  Published in Aging on December 29, 2020

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• Research PaperVolume 6, Issue 3pp 231-245

  Oxidative stress and antioxidant response in fibroblasts from Werner and Atypical Werner Syndromes

  Relevance score: 0.00

  Marta Seco-Cervera, Marta Spis, José Luis García-Giménez, José Santiago Ibañez-Cabellos, Ana Velázquez-Ledesma, Isabel Esmorís, Sergio Bañuls, Giselle Pérez-Machado, Federico V Pallardó

  Keywords: Werner Syndrome, Atypical Werner Syndrome, oxidative stress, antioxidant enzymes, thioredoxin, glutaredoxin, DNA damage, premature aging

  Published in Aging on March 31, 2014

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• Research PaperVolume 11, Issue 1pp 127-159

  Premature aging and cancer development in transgenic mice lacking functional CYLD

  Relevance score: 0.00

  Josefa P. Alameda, Ángel Ramírez, Rosa A. García-Fernández, Manuel Navarro, Angustias Page, José C. Segovia, Rebeca Sanchez, Cristian Suárez-Cabrera, Jesús M. Paramio, Ana Bravo, M. Jesús Fernández-Aceñero, M. Llanos Casanova

  Keywords: CYLD, premature aging, tumor suppressor, NF-κB, keratinocyte differentiation, skin, inflammation

  Published in Aging on January 10, 2019

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• Research PaperVolume 8, Issue 10pp 2392-2406

  Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice

  Relevance score: 0.00

  Joohwee Kim, Vivek Vaish, Mingxiao Feng, Kevin Field, Ioulia Chatzistamou, Minsub Shim

  Keywords: premature aging, COX2, TP53, p16, prostaglandin

  Published in Aging on October 7, 2016

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• Research PaperVolume 16, Issue 8pp 7277-7292

  Medium-chain chlorinated paraffins (MCCPs) induce renal cell aging and ferroptosis

  Relevance score: 0.00

  Dong Zhang, Zongying Li, Yuan Gao, Hailing Sun

  Keywords: MCCPs, premature aging, kidney, ferroptosis, inflammatory response

  Published in Aging on April 19, 2024

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• Research PaperVolume 16, Issue 3pp 2026-2046

  Defining the progeria phenome

  Relevance score: 0.00

  Cecilie Worm, Maya Elena Ramirez Schambye, Garik V. Mkrtchyan, Alexander Veviorskiy, Anastasia Shneyderman, Ivan V. Ozerov, Alex Zhavoronkov, Daniela Bakula, Morten Scheibye-Knudsen

  Keywords: aging, progeria, premature aging, phenome, clinical phenotype

  Published in Aging on February 9, 2024

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• Research PaperVolume 10, Issue 6pp 1223-1238

  Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine

  Relevance score: 0.00

  Megan E. Rowland, Yan Jiang, Frank Beier, Nathalie G. Bérubé

  Keywords: ATRX, premature aging, thyroid hormone, IGF-1, transcription

  Published in Aging on June 7, 2018

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• Research PaperVolume 11, Issue 12pp 4145-4158

  Intestinal stem cells acquire premature senescence and senescence associated secretory phenotype concurrent with persistent DNA damage after heavy ion radiation in mice

  Relevance score: 0.00

  Santosh Kumar, Shubhankar Suman, Albert J Fornace, Kamal Datta

  Keywords: heavy ion radiation, space radiation, radiotherapy, intestinal stem cell, senescence, premature aging, SASP

  Published in Aging on June 25, 2019

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• Research PerspectiveVolume 3, Issue 10pp 943-954

  ‘Relax and Repair’ to restrain aging

  Relevance score: 0.00

  Vaidehi Krishnan, Baohua Liu, Zhongjun Zhou

  Keywords: lamin A, DNA repair, chromatin, prelamin A, premature aging, histone acetylation, epigenetics, senescence, Zmpste24, HGPS

  Published in Aging on October 30, 2011

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• Research PerspectiveVolume 1, Issue 12pp 1028-1032

  The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging

  Relevance score: 0.00

  Daniel Edgar, Aleksandra Trifunovic

  Keywords: mtDNA mutator mice, mtDNA point mutations, mtDNA deletions, oxidative deficiency, premature aging

  Published in Aging on December 11, 2009

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• Research PaperVolume 5, Issue 8pp 607-622

  Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production

  Relevance score: 0.00

  Shubhankar Suman, Olga C. Rodriguez, Thomas A. Winters, Albert J. Fornace, Chris Albanese, Kamal Datta

  Keywords: Radiation, heavy ion radiation, premature aging, senescence, oxidative stress, DNA damage, cerebral cortex, long-term effects

  Published in Aging on August 6, 2013

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