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Volume 3, Issue 4

April 2011pp 329—454

Commentaries

A role for the cancer-associated miR-106b~25 cluster in neuronal stem cells

Barrie Peck, Almut Schulze

https://doi.org/10.18632/aging.100302pp 329—331

Put on your thinking cap: G-quadruplexes, helicases, and telomeres

Robert M. Brosh Jr.

https://doi.org/10.18632/aging.100307pp 332—335

A role for Ras signaling in modulating mammalian aging by the GH/IGF1 axis

João Pedro de Magalhães

https://doi.org/10.18632/aging.100309pp 336—337

A new look at old compounds

Silvestre Alavez, Gordon J. Lithgow

https://doi.org/10.18632/aging.100317pp 338—339

Conserved role of Ras-GEFs in promoting aging: from yeast to mice

Mario G. Mirisola, Valter D. Longo

https://doi.org/10.18632/aging.100320pp 340—343

Ku circles the telomere?

Christian Sell

https://doi.org/10.18632/aging.100321pp 344—345

Commentaries and Editorials

mTOR pathway activation in age-related retinal disease

Chen Zhao, Douglas Vollrath

https://doi.org/10.18632/aging.100303pp 346—347

Gerosuppressant Metformin: less is more

Javier A. Menendez, Sílvia Cufí, Cristina Oliveras-Ferraros, Luciano Vellon, Jorge Joven, Alejandro Vazquez-Martin

https://doi.org/10.18632/aging.100316pp 348—362

Review

Insights from model organisms on the functions of the tumor suppressor protein LKB1: Zebrafish chips in

Yme U. van der Velden, Anna-Pavlina G. Haramis

https://doi.org/10.18632/aging.100319pp 363—367

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Research Papers

Association of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population

Daria Zhebrun, Yulia Kudryashova, Alina Babenko, Alexei Maslyansky, Natalya Kunitskaya, Daria Popcova, Alexandra Klushina, Elena Grineva, Anna Kostareva, Evgeny Shlyakhto

https://doi.org/10.18632/aging.100305pp 368—373

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Long-term calorie restriction, but not endurance exercise, lowers core body temperature in humans

Andreea Soare, Roberto Cangemi, Daniela Omodei, John O. Holloszy, Luigi Fontana

https://doi.org/10.18632/aging.100280pp 374—379

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Generation of induced pluripotent stem cell lines from 3 distinct laminopathies bearing heterogeneous mutations in lamin A/C

Jenny CY Ho, Ting Zhou, Wing-Hon Lai, Yinghua Huang, Yau-Chi Chan, Xingyan Li, Navy LY Wong, Yanhua Li, Ka-Wing Au, Dongsheng Guo, Jianyong Xu, Chung-Wah Siu, Duanqing Pei, Hung-Fat Tse, Miguel Angel Esteban

https://doi.org/10.18632/aging.100277pp 380—390

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Pharmacological inhibition of NF-κB prolongs lifespan of Drosophila melanogaster

Alexey Moskalev, Mikhail Shaposhnikov

https://doi.org/10.18632/aging.100314pp 391—394

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Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells

Baomin Li, Sita Reddy, Lucio Comai

https://doi.org/10.18632/aging.100308pp 395—406

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Reversing the aging stromal phenotype prevents carcinoma initiation

Davina A. Lewis, Jeffrey B. Travers, Christiane Machado, Ally-Khan Somani, Dan F Spandau

https://doi.org/10.18632/aging.100318pp 407—416

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Accelerated in vivo epidermal telomere loss in Werner syndrome

Naoshi Ishikawa, Ken-Ichi Nakamura, Naotaka Izumiyama-Shimomura, Junko Aida, Akio Ishii, Makoto Goto, Yuichi Ishikawa, Reimi Asaka, Masaaki Matsuura, Atsushi Hatamochi, Mie Kuroiwa, Kaiyo Takubo

https://doi.org/10.18632/aging.100315pp 417—429

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Research Perspectives

The physiological roles of Sirt1 in skeletal muscle

Patricia S. Pardo, Aladin M. Boriek

https://doi.org/10.18632/aging.100312pp 430—437

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Reversing B cell aging

Ramit Mehr, Doron Melamed

https://doi.org/10.18632/aging.100313pp 438—443

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Resveratrol-activated SIRT1 in liver and pancreatic β-cells: a Janus head looking to the same direction of metabolic homeostasis

Laurène Vetterli, Pierre Maechler

https://doi.org/10.18632/aging.100304pp 444—449

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Hyperactive when young, hypoactive and overweight when aged: Connecting the dots in the story about locomotor activity, body mass, and aging in Trpv1 knockout mice

Samuel P. Wanner, Andras Garami, Andrej A. Romanovsky

https://doi.org/10.18632/aging.100306pp 450—454

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